{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T15:16:18Z","timestamp":1774019778404,"version":"3.50.1"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Schmerz"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1007\/s00482-026-00928-7","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T11:59:38Z","timestamp":1773748778000},"page":"132-143","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Regionalan\u00e4sthesie unter Antikoagulation","Regional anesthesia under anticoagulation"],"prefix":"10.1007","volume":"40","author":[{"given":"Simon-Friedrich","family":"Buhrmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Heubner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Vicent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter Markus","family":"Spieth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,17]]},"reference":[{"key":"928_CR1","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1097\/EJA.0b013e32833f6f6f","volume":"27","author":"W Gogarten","year":"2010","unstructured":"Gogarten\u00a0W, Vandermeulen\u00a0E, Van Aken\u00a0H et\u00a0al (2010) Regional anaesthesia and antithrombotic agents: recommendations of the European Society of Anaesthesiology. Eur J Anaesthesiol 27:999\u20131015. https:\/\/doi.org\/10.1097\/EJA.0b013e32833f6f6f","journal-title":"Eur J Anaesthesiol"},{"key":"928_CR2","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.sjpain.2016.11.008","volume":"15","author":"M Lagerkranser","year":"2017","unstructured":"Lagerkranser\u00a0M (2017) Neuraxial blocks and spinal haematoma: Review of 166 case reports published 1994\u20132015. Part\u00a01: Demographics and risk-factors. Scand J Pain 15:118\u2013129. https:\/\/doi.org\/10.1016\/j.sjpain.2016.11.008","journal-title":"Scandinavian Journal of Pain"},{"key":"928_CR3","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1007\/s12630-020-01827-w","volume":"68","author":"K Makito","year":"2021","unstructured":"Makito\u00a0K (2021) Spinal epidural hematoma and abscess after neuraxial anesthesia: a historical cohort study using the Japanese Diagnosis Procedure Combination database. Canadian Journal of Anesthesia\/Journal canadien d\u2019anesth\u00e9sie 68:42\u201352. https:\/\/doi.org\/10.1007\/s12630-020-01827-w","journal-title":"Canadian Journal of Anesthesia\/Journal canadien d\u2019anesth\u00e9sie"},{"key":"928_CR4","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1136\/rapm-2023-104864","volume":"50","author":"MR Schieber","year":"2025","unstructured":"Schieber\u00a0MR, Schubert\u00a0AK, Hubner\u00a0W et\u00a0al (2025) Influence of antithrombotic medication on size and neurological outcome of spinal epidural hematoma after neuraxial anesthesia: a systematic review. Reg Anesth Pain Med 50:20\u201325. https:\/\/doi.org\/10.1136\/rapm-2023-104864","journal-title":"Reg Anesth Pain Med"},{"key":"928_CR5","doi-asserted-by":"publisher","first-page":"111","DOI":"10.4103\/aca.aca_160_23","volume":"27","author":"P Laferri\u00e8re-Langlois","year":"2024","unstructured":"Laferri\u00e8re-Langlois\u00a0P, Jeffries\u00a0S, Harutyunyan\u00a0R et\u00a0al (2024) Epidural Catheterization in Cardiac Surgery: A Systematic Review and Risk Assessment of Epidural Hematoma. Annals of Cardiac Anaesthesia 27:111\u2013120. https:\/\/doi.org\/10.4103\/aca.aca_160_23","journal-title":"Annals of Cardiac Anaesthesia"},{"key":"928_CR6","unstructured":"Waurick (2021) \u201eR\u00fcckenmarksnahe Regionalan\u00e4sthesien und Thrombembolieprophylaxe\/antithrombotische Medikation\u201c."},{"key":"928_CR7","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.1097\/ALN.0000000000000253","volume":"120","author":"R D\u2019Angelo","year":"2014","unstructured":"D\u2019Angelo\u00a0R, Smiley\u00a0RM, Riley\u00a0ET et\u00a0al (2014) Serious Complications Related to Obstetric Anesthesia: The Serious Complication Repository Project of the Society for Obstetric Anesthesia and Perinatology. Anesthesiology 120:1505\u20131512. https:\/\/doi.org\/10.1097\/ALN.0000000000000253","journal-title":"Anesthesiology"},{"key":"928_CR8","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1515\/sjpain-2018-0041","volume":"18","author":"H Breivik","year":"2018","unstructured":"Breivik\u00a0H, Norum\u00a0H, Fenger-Eriksen\u00a0C et\u00a0al (2018) Reducing risk of spinal haematoma from spinal and epidural pain procedures. Scand J Pain 18:129\u2013150. https:\/\/doi.org\/10.1515\/sjpain-2018-0041","journal-title":"Scandinavian Journal of Pain"},{"key":"928_CR9","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1097\/EJA.0000000000001600","volume":"39","author":"S Kietaibl","year":"2022","unstructured":"Kietaibl\u00a0S, Ferrandis\u00a0R, Godier\u00a0A et\u00a0al (2022) Regional anaesthesia in patients on antithrombotic drugs: Joint ESAIC-ESRA\/ESRA guidelines. European Journal of Anaesthesiology 39:100\u2013132. https:\/\/doi.org\/10.1097\/EJA.0000000000001600","journal-title":"European Journal of Anaesthesiology"},{"key":"928_CR10","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-2024-105766","volume":"2025","author":"SL Kopp","year":"2025","unstructured":"Kopp\u00a0SL, Vandermeulen\u00a0E, McBane\u00a0RD et\u00a0al (2025) Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (fifth edition). Reg Anesth Pain Med 2025:rapm-2024-105766. https:\/\/doi.org\/10.1136\/rapm-2024-105766","journal-title":"Reg Anesth Pain Med"},{"key":"928_CR11","unstructured":"Feurstein\u00a0T Empfehlung der Arbeitsgruppe Perioperative Gerinnung der \u00d6GARI zum Thema: Regionalan\u00e4sthesie unter Gerinnungshemmung. https:\/\/www.oegari.at\/web_files\/cms_daten\/empfehlung_der_arbeitsgruppe_perioperative_gerinnung_der_ogari_zum_thema_regionalanasthesie_unter_gerinnungshemmung.pdf Heruntergeladen am 22.04.2025"},{"key":"928_CR12","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/j.accpm.2018.12.009","volume":"38","author":"F Joubert","year":"2019","unstructured":"Joubert\u00a0F, Gillois\u00a0P, Bouaziz\u00a0H et\u00a0al (2019) Bleeding complications following peripheral regional anaesthesia in patients treated with anticoagulants or antiplatelet agents: A systematic review. Anaesth Crit Care Pain Med 38:507\u2013516. https:\/\/doi.org\/10.1016\/j.accpm.2018.12.009","journal-title":"Anaesthesia Critical Care Pain Medicine"},{"key":"928_CR13","doi-asserted-by":"publisher","first-page":"1691","DOI":"10.1097\/00000539-200212000-00041","volume":"95","author":"TT Horlocker","year":"2002","unstructured":"Horlocker\u00a0TT, Bajwa\u00a0ZH, Ashraf\u00a0Z et\u00a0al (2002) Risk Assessment of Hemorrhagic Complications Associated with Nonsteroidal Antiinflammatory Medications in Ambulatory Pain Clinic Patients Undergoing Epidural Steroid Injection. Anesthesia Analgesia 95:1691\u20131697. https:\/\/doi.org\/10.1097\/00000539-200212000-00041","journal-title":"Anesthesia Analgesia"},{"key":"928_CR14","doi-asserted-by":"publisher","unstructured":"Gaus\u00a0P, Kutz\u00a0Ph, Bachtler\u00a0JA, et\u00a0al. Cave: Interskalenuskatheter. Anaesthesist 2017; 66: 961\u2013968. https:\/\/doi.org\/10.1007\/s00101-017-0365-6","DOI":"10.1007\/s00101-017-0365-6"},{"key":"928_CR15","unstructured":"Gemeinsamer Bundesausschuss, \u201eRichtlinie zur Versorgung der h\u00fcftgelenknahen Femurfraktur\/QSFFx-RL\u201c."},{"key":"928_CR16","doi-asserted-by":"publisher","DOI":"10.1111\/liv.70378","volume":"45","author":"K Ferdinande","year":"2025","unstructured":"Ferdinande\u00a0K, Campello\u00a0E, Simioni\u00a0P et\u00a0al (2025) Haemostatic Balance and Transfusion Strategies in Acute Liver Failure and Acute-On-Chronic Liver Failure: A Systematic Review. Liver Int 45:e70378. https:\/\/doi.org\/10.1111\/liv.70378","journal-title":"Liver International"},{"key":"928_CR17","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1111\/anae.15254","volume":"76","author":"D Oberladst\u00e4tter","year":"2021","unstructured":"Oberladst\u00e4tter\u00a0D, Voelckel\u00a0W, Schlimp\u00a0C et\u00a0al (2021) A prospective observational study of the rapid detection of clinically-relevant plasma direct oral anticoagulant levels following acute traumatic injury. Anaesthesia 76:373\u2013380. https:\/\/doi.org\/10.1111\/anae.15254","journal-title":"Anaesthesia"},{"key":"928_CR18","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1007\/s00101-025-01524-7","volume":"74","author":"M Mirus","year":"2025","unstructured":"Mirus\u00a0M, Sch\u00f6chl\u00a0H, Groene\u00a0P et\u00a0al (2025) Point-of-care-Gerinnungsdiagnostik \u2013 zwingend notwendig oder nur eine sinnvolle Erg\u00e4nzung? Anaesthesiologie 74:264\u2013274. https:\/\/doi.org\/10.1007\/s00101-025-01524-7","journal-title":"Anaesthesiologie"},{"key":"928_CR19","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1055\/s-0039-1700545","volume":"120","author":"J Harenberg","year":"2020","unstructured":"Harenberg\u00a0J, Beyer-Westendorf\u00a0J, Crowther\u00a0M et\u00a0al (2020) Accuracy of a Rapid Diagnostic Test for the Presence of Direct Oral Factor Xa or Thrombin Inhibitors in Urine\u2014A Multicenter Trial. J\u00a0Neurol Surg B Skull Base 120:132\u2013140. https:\/\/doi.org\/10.1055\/s-0039-1700545","journal-title":"Thromb Haemost"},{"key":"928_CR20","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1055\/s-0039-1700545","volume":"120","author":"J Harenberg","year":"2020","unstructured":"Harenberg\u00a0J, Beyer-Westendorf\u00a0J, Crowther\u00a0M et\u00a0al (2020) Accuracy of a Rapid Diagnostic Test for the Presence of Direct Oral Factor Xa or Thrombin Inhibitors in Urine\u2014A Multicenter Trial. J\u00a0Neurol Surg B Skull Base 120:132\u2013140. https:\/\/doi.org\/10.1055\/s-0039-1700545","journal-title":"Thromb Haemost"},{"key":"928_CR21","doi-asserted-by":"publisher","first-page":"1723","DOI":"10.1055\/s-0042-1750327","volume":"122","author":"AE Merrelaar","year":"2022","unstructured":"Merrelaar\u00a0AE, B\u00f6gl\u00a0MS, Buchtele\u00a0N et\u00a0al (2022) Performance of a Qualitative Point-of-Care Strip Test to Detect DOAC Exposure at the Emergency Department: A Cohort-Type Cross-Sectional Diagnostic Accuracy Study. Z Geburtshilfe Neonatol 122:1723\u20131731. https:\/\/doi.org\/10.1055\/s-0042-1750327","journal-title":"Thromb Haemost"},{"key":"928_CR22","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1016\/j.bja.2017.11.105","volume":"120","author":"EME Bos","year":"2018","unstructured":"Bos\u00a0EME, Haumann\u00a0J, De Quelerij\u00a0M et\u00a0al (2018) Haematoma and abscess after neuraxial anaesthesia: a review of 647 cases. Br J Anaesth 120:693\u2013704. https:\/\/doi.org\/10.1016\/j.bja.2017.11.105","journal-title":"British Journal of Anaesthesia"},{"key":"928_CR23","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24054665","volume":"24","author":"DH Pozza","year":"2023","unstructured":"Pozza\u00a0DH, Tavares\u00a0I, Cruz\u00a0CD et\u00a0al (2023) Spinal Cord Injury and Complications Related to Neuraxial Anaesthesia Procedures: A Systematic Review. International Journal of Molecular Sciences 24:4665. https:\/\/doi.org\/10.3390\/ijms24054665","journal-title":"IJMS"},{"key":"928_CR24","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1001\/archsurg.143.10.990","volume":"143","author":"DM P\u00f6pping","year":"2008","unstructured":"P\u00f6pping\u00a0DM, Elia\u00a0N, Marret\u00a0E et\u00a0al (2008) Protective effects of epidural analgesia on pulmonary complications after abdominal and thoracic surgery: a meta-- analysis. Arch Surg 143:990\u2013999","journal-title":"Arch Surg"},{"key":"928_CR25","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1097\/00000542-200410000-00021","volume":"101","author":"V Moen","year":"2004","unstructured":"Moen\u00a0V, Dahlgren\u00a0N, Irestedt\u00a0L (2004) Severe Neurological Complications after Central Neuraxial Blockades in Sweden 1990\u20131999. Anesthesiology 101:950\u2013959","journal-title":"Anesthesiology"},{"key":"928_CR26","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1213\/00000539-196707000-00017","volume":"46","author":"JE Usubiaga","year":"1967","unstructured":"Usubiaga\u00a0JE, Wikinski\u00a0JA, Usubiaga\u00a0LE (1967) Epidural pressure and its relation to spread of anesthetic solutions in epidural space. Anesth Analg 46:440\u2013446","journal-title":"Anesth Analg"}],"container-title":["Der Schmerz"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00482-026-00928-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00482-026-00928-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00482-026-00928-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T13:51:35Z","timestamp":1774014695000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00482-026-00928-7"}},"subtitle":["Leitlinienabgleich und Handlungsempfehlungen","Comparison of guidelines and recommendations for action"],"short-title":[],"issued":{"date-parts":[[2026,3,17]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["928"],"URL":"https:\/\/doi.org\/10.1007\/s00482-026-00928-7","relation":{},"ISSN":["0932-433X","1432-2129"],"issn-type":[{"value":"0932-433X","type":"print"},{"value":"1432-2129","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,17]]},"assertion":[{"value":"5 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"Gem\u00e4\u00df den Richtlinien des Springer Medizin Verlags werden Autoren und Wissenschaftliche Leitung im Rahmen der Manuskripterstellung und Manuskriptfreigabe aufgefordert, eine vollst\u00e4ndige Erkl\u00e4rung zu ihren finanziellen und nichtfinanziellen Interessen abzugeben.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"S.-F.\u00a0Buhrmann\n                      : A.\u00a0Finanzielle Interessen: S.-F.\u00a0Buhrmann gibt an, dass kein finanzieller Interessenkonflikt besteht. \u2013\u00a0B.\u00a0Nichtfinanzielle Interessen: Arzt in Weiterbildung, Klinik f\u00fcr An\u00e4sthesiologie, operative Intensivmedizin und Schmerzmedizin, Universit\u00e4tsklinikum M\u00fcnster M\u00e4rz 2023 bis M\u00e4rz 2024; Arzt in Weiterbildung, Klinik und Poliklinik f\u00fcr An\u00e4sthesiologie und Intensivtherapie, Universit\u00e4tsklinikum Carl Gustav Carus der Technischen Universit\u00e4t Dresden seit April 2024.\n                      L.\u00a0Heubner\n                      : A.\u00a0Finanzielle Interessen: Forschungsf\u00f6rderung zur pers\u00f6nlichen Verf\u00fcgung: Werfen, Haemonetics, Apiro.\u00a0\u2013 Vortragshonorare von AstraZeneca, CSL Behring, Octapharma, Takeda, Werfen. \u2013\u00a0Apiro: Beratert\u00e4tigkeit; AstraZeneca: Advisory Board, Beratert\u00e4tigkeit; Octapharma: Beratert\u00e4tigkeit; Takeda: Advisory Board.\u00a0\u2013 B.\u00a0Nichtfinanzielle Interessen: Angestellter An\u00e4sthesist, Universit\u00e4tsklinikum Carl Gustav Carus der Technischen Universit\u00e4t Dresden | Mitarbeit an diversen Leitlinien der Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF, u.\u202fa. S3 Polytrauma, S2k r\u00fcckenmarksnahe Regionalan\u00e4sthesien und Thrombembolieprophylaxe\/antithrombotische Medikation, S2k Therapie angeborener thrombozyt\u00e4rer Erkrankungen) | Mitgliedschaften: Deutsche Gesellschaft f\u00fcr An\u00e4sthesiologie und Intensivmedizin (DGAI), Deutsche Interdisziplin\u00e4re Vereinigung f\u00fcr Intensiv- und Notfallmedizin (DIVI), Gesellschaft f\u00fcr Thrombose- und H\u00e4mostaseforschung (GTH).\n                      O.\u00a0Vicent\n                      : A.\u00a0Finanzielle Interessen: Vortragshonorare und Reisekostenerstattung der Firmen CSL Behring und AstraZeneca. \u2013\u00a0B.\u00a0Nichtfinanzielle Interessen: Angestellter An\u00e4sthesist in ober\u00e4rztlicher Position, Klinik und Poliklinik f\u00fcr An\u00e4sthesiologie und Intensivtherapie, Universit\u00e4tsklinikum Carl Gustav Carus der Technischen Universit\u00e4t Dresden | Mitgliedschaften: Deutsche Gesellschaft f\u00fcr Ultraschall in der Medizin (DEGUM), Berufsverband Deutscher An\u00e4sthesistinnen und An\u00e4sthesisten (BDA), DGAI, European Society of Regional Anaesthesia\u00a0& Pain Therapy (ESRA).\n                      P.M.\u00a0Spieth\n                      : A.\u00a0Finanzielle Interessen: P.M.\u00a0Spieth gibt an, dass kein finanzieller Interessenkonflikt besteht.\u00a0\u2013 B.\u00a0Nichtfinanzielle Interessen: Angestellter An\u00e4sthesist, Klinik f\u00fcr An\u00e4sthesiologie und Intensivtherapie, Universit\u00e4tsklinikum Carl Gustav Carus der Technischen Universit\u00e4t Dresden | Mitgliedschaften: DGAI, BDA, European Society of Intensive Care Medicine (ESICM), European Society of Anaesthesiology and Intensive Care (ESAIC), Extracorporeal Life Support Organization (ELSO).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Autoren"}},{"value":"Die vollst\u00e4ndige Erkl\u00e4rung zum Interessenkonflikt der Wissenschaftlichen Leitung finden Sie am Kurs der zertifizierten Fortbildung auf\n                      \n                      .","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Wissenschaftliche Leitung"}},{"value":"erkl\u00e4rt, dass f\u00fcr die Publikation dieser CME-Fortbildung keine Sponsorengelder an den Verlag flie\u00dfen.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Der Verlag"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Der Verlag"}}]}}