{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:58:14Z","timestamp":1761541094050},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"9-10","license":[{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wien Klin Wochenschr"],"published-print":{"date-parts":[[2012,5]]},"DOI":"10.1007\/s00508-012-0171-8","type":"journal-article","created":{"date-parts":[[2012,5,10]],"date-time":"2012-05-10T11:45:02Z","timestamp":1336650302000},"page":"320-325","source":"Crossref","is-referenced-by-count":14,"title":["Heparin-induced effects of prothrombin complex concentrates in thromboelastometry"],"prefix":"10.1007","volume":"124","author":[{"given":"Gisela","family":"Scharbert","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"Thaler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Weilnb\u00f6ck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e9onore","family":"Wetzel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sibylle","family":"Kozek-Langenecker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,5,11]]},"reference":[{"key":"171_CR1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0049-3848(99)00077-8","volume":"95","author":"P Hellstern","year":"1999","unstructured":"Hellstern P, Halbmayer WM, Kohler M, Seitz R, Muller-Berghaus G. Prothrombin complex concentrates: indications, contraindications, and risks: a task force summary. Thromb Res. 1999;95:3\u20136.","journal-title":"Thromb Res."},{"key":"171_CR2","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1111\/j.1538-7836.2006.01815.x","volume":"4","author":"MW Lankiewicz","year":"2006","unstructured":"Lankiewicz MW, Hays J, Friedman KD, Tinkoff G, Blatt PM. Urgent reversal of warfarin with prothrombin complex concentrate. J Thromb Haemost. 2006;4:967\u201370.","journal-title":"J Thromb Haemost."},{"key":"171_CR3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.mbc.0000256021.16453.de","volume":"18","author":"M Takeyama","year":"2007","unstructured":"Takeyama M, Sakurai Y, Shima M, Matsumoto T, Nogami K, Tanaka I, et al. Heparin-induced inhibitory effects of a prothrombin complex concentrate on global tests of haemostasis. Blood Coagul Fibrinolysis. 2007;18:1\u20137.","journal-title":"Blood Coagul Fibrinolysis."},{"key":"171_CR4","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1111\/j.1538-7836.2008.02904.x","volume":"6","author":"I Pabinger","year":"2008","unstructured":"Pabinger I, Brenner B, Kalina U, Knaub S, Nagy A, Ostermann H. Prothrombin complex concentrate (Beriplex P\/N) for emergency anticoagulation reversal: a prospective multinational clinical trial. J Thromb Haemost. 2008;6:622\u201331.","journal-title":"J Thromb Haemost."},{"key":"171_CR5","first-page":"121","volume":"57","author":"E Lavenne-Pardonge","year":"2006","unstructured":"Lavenne-Pardonge E, Itegwa MA, Kalaai M, Klinkenberg G, Loncke JL, Pelgrims K, et al. Emergency reversal of oral anticoagulation through PPSB-SD: the fastest procedure in Belgium. Acta Anaesthesiol Belg. 2006;57:121\u20135.","journal-title":"Acta Anaesthesiol Belg."},{"key":"171_CR6","first-page":"401","volume":"73","author":"S. Kozek-Langenecker","year":"2007","unstructured":"Kozek-Langenecker S. Management of massive operative blood loss. Minerva Anestesiol. 2007;73:401\u201315.","journal-title":"Minerva Anestesiol."},{"key":"171_CR7","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1111\/j.1742-1241.2008.01859.x","volume":"62","author":"U Kalina","year":"2008","unstructured":"Kalina U, Bickhard H, Schulte S. Biochemical comparison of seven commercially available prothrombin complex concentrates. Int J Clin Pract. 2008;62:1614\u201322.","journal-title":"Int J Clin Pract."},{"issue":"6","key":"171_CR8","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1097\/00000539-200212000-00008","volume":"95","author":"VG Nielsen","year":"2002","unstructured":"Nielsen VG. The detection of changes in heparin activity in the rabbit: a comparison of anti-Xa activity, thromboelastography, activated partial thromboplastin time, and activated coagulation time. Anesth analg. 2002;95(6):1503\u20136.","journal-title":"Anesth analg."},{"issue":"5","key":"171_CR9","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1213\/00000539-200011000-00009","volume":"91","author":"SM Klein","year":"2000","unstructured":"Klein SM, Slaughter TF, Vail PT, Ginsberg B, El-Moalem HE, Alexander R, et al. Thromboelastography as a perioperative measure of anticoagulation resulting from low molecular weight heparin: a comparison with anti-Xa concentrations. Anesth analg. 2000;91(5):1091\u20135.","journal-title":"Anesth analg."},{"issue":"5","key":"171_CR10","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1309\/Q4AE-BMCW-CQ7J-NUVT","volume":"113","author":"K Zmuda","year":"2000","unstructured":"Zmuda K, Neofotistos D, Ts\u2019ao CH. Effects of unfractionated heparin, low-molecular-weight heparin, and heparinoid on thromboelastographic assay of blood coagulation. Am J clin pathol. 2000;113(5):725\u201331.","journal-title":"Am J clin pathol"},{"key":"171_CR11","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1007\/s00101-007-1182-0","volume":"56","author":"G Pfanner","year":"2007","unstructured":"Pfanner G, Koscielny J, Pernerstorfer T, Gutl M, Perger P, Fries D, et al. Preoperative evaluation of the bleeding history. Recommendations of the working group on perioperative coagulation of the Austrian Society for Anaesthesia, Resuscitation and Intensive Care. Anaesthesist. 2007;56:604\u201311.","journal-title":"Anaesthesist."},{"key":"171_CR12","doi-asserted-by":"crossref","first-page":"R55","DOI":"10.1186\/cc8948","volume":"14","author":"H Schochl","year":"2010","unstructured":"Schochl H, Nienaber U, Hofer G, Voelckel W, Jambor C, Scharbert G, et al. Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM)-guided administration of fibrinogen concentrate and prothrombin complex concentrate. Crit Care. 2010;14:R55.","journal-title":"Crit Care."},{"issue":"3\u20134","key":"171_CR13","doi-asserted-by":"crossref","first-page":"266","DOI":"10.2119\/molmed.2010.00159","volume":"17","author":"H Schochl","year":"2011","unstructured":"Schochl H, Solomon C, Schulz A, Voelckel W, Hanke A, Van Griensven M,et al. Thromboelastometry (Tem) findings in disseminated intravascular coagulation in a pig model of endotoxinemia. Mol Med. 2011;17(3\u20134):266\u201372.","journal-title":"Mol Med."},{"key":"171_CR14","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1097\/00000539-200005000-00015","volume":"90","author":"VA Bowbrick","year":"2000","unstructured":"Bowbrick VA, Mikhailidis DP, Stansby G. The use of citrated whole blood in thromboelastography. Anesth Analg. 2000;90:1086\u20138.","journal-title":"Anesth Analg."},{"key":"171_CR15","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1365-2257.2005.00681.x","volume":"27","author":"RJ Luddington","year":"2005","unstructured":"Luddington RJ. Thrombelastography\/thromboelastometry. Clin Lab Haematol. 2005;27:81\u201390.","journal-title":"Clin Lab Haematol."},{"key":"171_CR16","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1097\/01.mbc.0000169225.31173.19","volume":"16","author":"T Lang","year":"2005","unstructured":"Lang T, Bauters A, Braun SL, Potzsch B, von Pape KW, Kolde HJ, et al. Multi-centre investigation on reference ranges for ROTEM thromboelastometry. Blood Coagul Fibrinolysis. 2005;16:301\u201310.","journal-title":"Blood Coagul Fibrinolysis."},{"key":"171_CR17","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.thromres.2005.08.005","volume":"118","author":"L van Aart","year":"2006","unstructured":"van Aart L, Eijkhout HW, Kamphuis JS, Dam M, Schattenkerk ME, Schouten TJ, et al. Individualized dosing regimen for prothrombin complex concentrate more effective than standard treatment in the reversal of oral anticoagulant therapy: an open, prospective randomized controlled trial. Thromb Res. 2006;118:313\u201320.","journal-title":"Thromb Res."},{"key":"171_CR18","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1007\/s001340051019","volume":"25","author":"T Staudinger","year":"1999","unstructured":"Staudinger T, Frass M, Rintelen C, Quehenberger P, Wagner O, Stoiser B,et al. Influence of prothrombin complex concentrates on plasma coagulation in critically ill patients. Intensive Care Med. 1999;25:1105\u201310.","journal-title":"Intensive Care Med."},{"key":"171_CR19","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/S0140-6736(76)91794-3","volume":"2","author":"PM Mannucci","year":"1976","unstructured":"Mannucci PM, Franchi F, Dioguardi N. Correction of abnormal coagulation in chronic liver disease by combined use of fresh-frozen plasma and prothrombin complex concentrates. Lancet. 1976;2:542\u20135.","journal-title":"Lancet."},{"key":"171_CR20","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1161\/01.STR.0000221786.81354.d6","volume":"37","author":"HB Huttner","year":"2006","unstructured":"Huttner HB, Schellinger PD, Hartmann M, Kohrmann M, Juettler E, Wikner J, et al. Hematoma growth and outcome in treated neurocritical care patients with intracerebral hemorrhage related to oral anticoagulant therapy: comparison of acute treatment strategies using vitamin K, fresh frozen plasma, and prothrombin complex concentrates. Stroke. 2006;37:1465\u201370.","journal-title":"Stroke."},{"key":"171_CR21","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1378\/chest.08-0677","volume":"133","author":"TE Warkentin","year":"2008","unstructured":"Warkentin TE, Greinacher A, Koster A, Lincoff AM. Treatment and prevention of heparin-induced thrombocytopenia: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133:340\u201380.","journal-title":"Chest."},{"key":"171_CR22","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1111\/j.1538-7836.2008.03054.x","volume":"6","author":"H Buller","year":"2008","unstructured":"Buller H, Deitchman D, Prins M, Segers A. Efficacy and safety of the oral direct factor Xa inhibitor apixaban for symptomatic deep vein thrombosis. The Botticelli DVT dose-ranging study. J Thromb Haemost. 2008;6:1313\u20138.","journal-title":"J Thromb Haemost."},{"key":"171_CR23","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.1182\/blood-2008-05-160143","volume":"112","author":"HR Buller","year":"2008","unstructured":"Buller HR, Lensing AW, Prins MH, Agnelli G, Cohen A, Gallus AS, et al. A dose-ranging study evaluating once-daily oral administration of the factor Xa inhibitor rivaroxaban in the treatment of patients with acute symptomatic deep vein thrombosis: the Einstein-DVT dose-ranging study. Blood. 2008;112:2242\u20137.","journal-title":"Blood."},{"key":"171_CR24","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/nrd2622","volume":"7","author":"BI Eriksson","year":"2008","unstructured":"Eriksson BI, Smith H, Yasothan U, Kirkpatrick P. Dabigatran etexilate. Nat Rev Drug Discov. 2008;7:557\u20138.","journal-title":"Nat Rev Drug Discov."},{"key":"171_CR25","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/S0140-6736(07)61445-7","volume":"370","author":"BI Eriksson","year":"2007","unstructured":"Eriksson BI, Dahl OE, Rosencher N, Kurth AA, van Dijk CN, Frostick SP, et al. Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial. Lancet. 2007;370:949\u201356.","journal-title":"Lancet."},{"key":"171_CR26","first-page":"68","volume":"68","author":"MM Levi","year":"2010","unstructured":"Levi MM, Eerenberg E, Lowenberg E, Kamphuisen PW. Bleeding in patients using new anticoagulants or antiplatelet agents: risk factors and management. Neth J Med. 2010;68:68\u201376.","journal-title":"Neth J Med."},{"key":"171_CR27","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1213\/01.ANE.0000155290.86795.12","volume":"100","author":"DJ McCrath","year":"2005","unstructured":"McCrath DJ, Cerboni E, Frumento RJ, Hirsh AL, Bennett-Guerrero E. Thromboelastography maximum amplitude predicts postoperative thrombotic complications including myocardial infarction. Anesth Analg. 2005;100:1576\u201383.","journal-title":"Anesth Analg."},{"key":"171_CR28","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1093\/bja\/aei197","volume":"95","author":"M Mittermayr","year":"2005","unstructured":"Mittermayr M, Margreiter J, Velik-Salchner C, Klingler A, Streif W, Fries D, et al. Effects of protamine and heparin can be detected and easily differentiated by modified thrombelastography (Rotem): an in vitro study. Br J Anaesth. 2005;95:310\u20136.","journal-title":"Br J Anaesth."}],"container-title":["Wiener klinische Wochenschrift"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00508-012-0171-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00508-012-0171-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00508-012-0171-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,28]],"date-time":"2019-06-28T10:00:22Z","timestamp":1561716022000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00508-012-0171-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5]]},"references-count":28,"journal-issue":{"issue":"9-10","published-print":{"date-parts":[[2012,5]]}},"alternative-id":["171"],"URL":"https:\/\/doi.org\/10.1007\/s00508-012-0171-8","relation":{},"ISSN":["0043-5325","1613-7671"],"issn-type":[{"value":"0043-5325","type":"print"},{"value":"1613-7671","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5]]}}}