{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:34:12Z","timestamp":1761129252256},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"S8","license":[{"start":{"date-parts":[[2015,4,28]],"date-time":"2015-04-28T00:00:00Z","timestamp":1430179200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2015,4,28]],"date-time":"2015-04-28T00:00:00Z","timestamp":1430179200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Wien Klin Wochenschr"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1007\/s00508-015-0773-z","type":"journal-article","created":{"date-parts":[[2015,4,27]],"date-time":"2015-04-27T06:24:40Z","timestamp":1430115880000},"page":"614-619","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Variables determining the development of colistin-associated renal impairment"],"prefix":"10.1007","volume":"128","author":[{"given":"Bahad\u0131r","family":"Ceylan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00fcd\u00fcr","family":"Tani\u015f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammed Emin","family":"Akkoyunlu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"\u00c7\u0131nar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ay\u015fe Ruhkar","family":"Kurt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasemin","family":"Akkoyunlu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didem","family":"Ozkan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatice Kutbay","family":"Ozcelik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Turan","family":"Aslan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muzaffer","family":"Fincanc\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u015eule","family":"Vatansever","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kadir","family":"\u0130din","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emine","family":"Guler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harun","family":"Uysal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,4,28]]},"reference":[{"issue":"4","key":"773_CR1","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1097\/00003246-200104001-00004","volume":"29","author":"GW Waterer","year":"2001","unstructured":"Waterer GW, Wunderink RG. Increasing threat of gram-negative bacteria. Crit Care Med. 2001;29(4):75\u201381.","journal-title":"Crit Care Med"},{"issue":"9","key":"773_CR2","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1093\/cid\/cir611","volume":"53","author":"JM Pogue","year":"2011","unstructured":"Pogue JM, Lee J, Marchaim D, et al. Incidence of and risk factors for colistin-associated nephrotoxicity in a large academic health system. Clin Infect Dis. 2011;53(9):879\u201384.","journal-title":"Clin Infect Dis"},{"issue":"5","key":"773_CR3","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1016\/j.ijantimicag.2009.12.002","volume":"35","author":"JA Kwon","year":"2010","unstructured":"Kwon JA, Lee JE, Huh W, et al. Predictors of acute kidney injury associated with intravenous colistin treatment. Int J Antimicrob Agents. 2010;35(5):473\u20137.","journal-title":"Int J Antimicrob Agents"},{"issue":"1","key":"773_CR4","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.jinf.2012.01.015","volume":"65","author":"CJ Kubin","year":"2012","unstructured":"Kubin CJ, Ellman TM, Phadke V, Haynes LJ, Calfee DP, Yin MT. Incidence and predictors of acute kidney injury associated with intravenous polymyxin B therapy. J Infect. 2012;65(1):80\u20137.","journal-title":"J Infect"},{"issue":"9","key":"773_CR5","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.2169\/internalmedicine.50.4270","volume":"50","author":"N Durakovic","year":"2011","unstructured":"Durakovic N, Radojcic V, Boban A, et al. Efficacy and safety of colistin in the treatment of infections caused by multidrug-resistant Pseudomonas aeruginosa in patients with hematologic malignancy: a matched pair analysis. Intern Med. 2011;50(9):1009\u201313.","journal-title":"Intern Med"},{"issue":"5","key":"773_CR6","doi-asserted-by":"publisher","first-page":"2392","DOI":"10.1128\/AAC.00028-12","volume":"56","author":"TP Gauthier","year":"2012","unstructured":"Gauthier TP, Wolowich WR, Reddy A, Cano E, Abbo L, Smith LB. Incidence and predictors of nephrotoxicity associated with intravenous colistin in overweight and obese patients. Antimicrob Agents Chemother. 2012;56(5):2392\u20136.","journal-title":"Antimicrob Agents Chemother"},{"issue":"5","key":"773_CR7","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1007\/s15010-009-8342-x","volume":"37","author":"M Montero","year":"2009","unstructured":"Montero M, Horcajada JP, Sorl\u00ed L, et al. Effectiveness and safety of colistin for the treatment of multidrug-resistant Pseudomonas aeruginosa infections. Infection. 2009;37(5):461\u20135.","journal-title":"Infection"},{"issue":"5","key":"773_CR8","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1016\/j.ijantimicag.2009.06.028","volume":"34","author":"J Kim","year":"2009","unstructured":"Kim J, Lee KH, Yoo S, Pai H. Clinical characteristics and risk factors of colistin-induced nephrotoxicity. Int J Antimicrob Agents. 2009;34(5):434\u20138.","journal-title":"Int J Antimicrob Agents"},{"issue":"3","key":"773_CR9","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.ijantimicag.2009.11.016","volume":"35","author":"CY Cheng","year":"2010","unstructured":"Cheng CY, Sheng WH, Wang JT, Chen YC, Chang SC. Safety and efficacy of intravenous colistin (colistin methanesulphonate) for severe multidrug-resistant gram-negative bacterial infections. Int J Antimicrob Agents. 2010;35(3):297\u2013300.","journal-title":"Int J Antimicrob Agents"},{"issue":"5","key":"773_CR10","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1093\/jac\/dkq069","volume":"65","author":"M Paul","year":"2010","unstructured":"Paul M, Bishara J, Levcovich A, et al. Effectiveness and safety of colistin: prospective comparative cohort study. J Antimicrob Chemother. 2010;65(5):1019\u201327.","journal-title":"J Antimicrob Chemother"},{"issue":"10","key":"773_CR11","doi-asserted-by":"publisher","first-page":"4503","DOI":"10.1128\/AAC.01707-09","volume":"54","author":"CA Deryke","year":"2010","unstructured":"Deryke CA, Crawford AJ, Uddin N, Wallace MR. Colistin dosing and nephrotoxicity in a large community teaching hospital. Antimicrob Agents Chemother. 2010;54(10):4503\u20135.","journal-title":"Antimicrob Agents Chemother"},{"issue":"2","key":"773_CR12","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1093\/jac\/dkm509","volume":"61","author":"M Bassetti","year":"2008","unstructured":"Bassetti M, Repetto E, Righi E, et al. Colistin and rifampicin in the treatment of multidrug-resistant Acinetobacter baumannii infections. J Antimicrob Chemother. 2008;61(2):417\u201320.","journal-title":"J Antimicrob Chemother"},{"issue":"7","key":"773_CR13","doi-asserted-by":"publisher","first-page":"1162","DOI":"10.1007\/s00134-007-0675-2","volume":"33","author":"H Kallel","year":"2007","unstructured":"Kallel H, Hergafi L, Bahloul M, et al. Safety and efficacy of colistin compared with imipenem in the treatment of ventilator-associated pneumonia: a matched case-control study. Intensive Care Med. 2007;33(7):1162\u20137.","journal-title":"Intensive Care Med"},{"issue":"9","key":"773_CR14","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1086\/374337","volume":"36","author":"J Garnacho-Montero","year":"2003","unstructured":"Garnacho-Montero J, Ortiz-Leyba C, Jim\u00e9nez-Jim\u00e9nez FJ, et al. Treatment of multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia (VAP) with intravenous colistin: a comparison with imipenem-susceptible VAP. Clin Infect Dis. 2003;36(9):1111\u20138.","journal-title":"Clin Infect Dis"},{"issue":"5","key":"773_CR15","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1086\/514732","volume":"28","author":"AS Levin","year":"1999","unstructured":"Levin AS, Barone AA, Pen\u00e7o J, et al. Intravenous colistin as therapy for nosocomial infections caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii. Clin Infect Dis. 1999;28(5):1008\u201311.","journal-title":"Clin Infect Dis"},{"issue":"2","key":"773_CR16","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/j.ijantimicag.2009.10.005","volume":"35","author":"ME Falagas","year":"2010","unstructured":"Falagas ME, Rafailidis PI, Ioannidou E, et al. Colistin therapy for microbiologically documented multidrug-resistant gram-negative bacterial infections: a retrospective cohort study of 258 patients. Int J Antimicrob Agents. 2010;35(2):194\u20139.","journal-title":"Int J Antimicrob Agents"},{"issue":"6","key":"773_CR17","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.1128\/AAC.01015-06","volume":"51","author":"RY Hachem","year":"2007","unstructured":"Hachem RY, Chemaly RF, Ahmar CA, et al. Colistin is effective in treatment of infections caused by multidrug-resistant Pseudomonas aeruginosa in cancer patients. Antimicrob Agents Chemother. 2007;51(6):1905\u201311.","journal-title":"Antimicrob Agents Chemother"},{"issue":"6","key":"773_CR18","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1093\/jac\/dkn128","volume":"61","author":"MS Oliveira","year":"2008","unstructured":"Oliveira MS, Prado GV, Costa SF, Grinbaum RS, Levin AS. Ampicillin\/sulbactam compared with polymyxins for the treatment of infections caused by carbapenem-resistant Acinetobacter spp. J Antimicrob Chemother. 2008;61(6):1369\u201375.","journal-title":"J Antimicrob Chemother"},{"key":"773_CR19","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/1471-2334-9-26","volume":"9","author":"R Gounden","year":"2009","unstructured":"Gounden R, Bamford C, van Zyl-Smit R, Cohen K, Maartens G. Safety and effectiveness of colistin compared with tobramycin for multi-drug resistant Acinetobacter baumannii infections. BMC Infect Dis. 2009;9:26.","journal-title":"BMC Infect Dis"},{"issue":"3","key":"773_CR20","doi-asserted-by":"publisher","first-page":"325","DOI":"10.3346\/jkms.2011.26.3.325","volume":"26","author":"SK Lim","year":"2011","unstructured":"Lim SK, Lee SO, Choi SH, et al. The outcomes of using colistin for treating multidrug resistant Acinetobacter species bloodstream infections. J Korean Med Sci. 2011;26(3):325\u201331.","journal-title":"J Korean Med Sci"},{"issue":"1","key":"773_CR21","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1093\/jac\/dkq390","volume":"66","author":"CH Kvitko","year":"2011","unstructured":"Kvitko CH, Rigatto MH, Moro AL, Zavascki AP. Polymyxin B versus other antimicrobials for the treatment of Pseudomonas aeruginosa bacteraemia. J Antimicrob Chemother. 2011;66(1):175\u20139.","journal-title":"J Antimicrob Chemother"},{"issue":"8","key":"773_CR22","doi-asserted-by":"publisher","first-page":"2659","DOI":"10.1128\/AAC.47.8.2659-2662.2003","volume":"47","author":"JP Ouderkirk","year":"2003","unstructured":"Ouderkirk JP, Nord JA, Turett GS, Kislak JW. Polymyxin B nephrotoxicity and efficacy against nosocomial infections caused by multiresistant gram-negative bacteria. Antimicrob Agents Chemother. 2003;47(8):2659\u201362.","journal-title":"Antimicrob Agents Chemother"},{"issue":"3","key":"773_CR23","doi-asserted-by":"publisher","first-page":"1442","DOI":"10.1128\/AAC.01329-12","volume":"57","author":"MM Mostardeiro","year":"2013","unstructured":"Mostardeiro MM, Pereira CA, Marra AR, Pestana JO, Camargo LF. Nephrotoxicity and efficacy assessment of polymyxin use in 92 transplant patients. Antimicrob Agents Chemother. 2013;57(3):1442\u20136.","journal-title":"Antimicrob Agents Chemother"},{"issue":"12","key":"773_CR24","doi-asserted-by":"publisher","first-page":"1724","DOI":"10.1086\/599225","volume":"48","author":"JD Hartzell","year":"2009","unstructured":"Hartzell JD, Neff R, Ake J, Wortmann G. et al. Nephrotoxicity associated with intravenous colistin (colistimethate sodium) treatment at a tertiary care medical center. Clin Infect Dis. 2009;48(12):1724\u20138.","journal-title":"Clin Infect Dis"},{"issue":"3","key":"773_CR25","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1159\/000320746","volume":"117","author":"Hj Ko","year":"2011","unstructured":"Ko Hj, Jeon Mh, Choo Ej, et al. Early acute kidney injury is a risk factor that predicts mortality in patients treated with colistin. Nephron Clin Pract. 2011;117(3):284\u20138.","journal-title":"Nephron Clin Pract"},{"issue":"4","key":"773_CR26","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1159\/000142926","volume":"109","author":"JA Kellum","year":"2008","unstructured":"Kellum JA, Bellomo R, Ronco C. Definition and classification of acute kidney injury. Nephron Clin Pract. 2008;109(4):182\u20137.","journal-title":"Nephron Clin Pract"},{"key":"773_CR27","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/S0140-6736(74)91639-0","volume":"2","author":"G Teasdale","year":"1974","unstructured":"Teasdale G, Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet. 1974;2:81\u20134.","journal-title":"Lancet"},{"issue":"2","key":"773_CR28","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1152\/ajpcell.00213.2006","volume":"292","author":"A Navarro","year":"2007","unstructured":"Navarro A, Boveris A. The mitochondrial energy transduction system and the aging process. Am J Physiol Cell Physiol. 2007;292(2):670\u201386.","journal-title":"Am J Physiol Cell Physiol"},{"issue":"4","key":"773_CR29","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1016\/j.cell.2005.02.001","volume":"120","author":"RS Balaban","year":"2005","unstructured":"Balaban RS, Nemoto S, Finkel T. Mitochondria, oxidants, and aging. Cell. 2005;120(4):483\u201395.","journal-title":"Cell"},{"issue":"9","key":"773_CR30","doi-asserted-by":"publisher","first-page":"4044","DOI":"10.1128\/AAC.00328-11","volume":"55","author":"JM Yousef","year":"2011","unstructured":"Yousef JM, Chen G, Hill PA, Nation RL, Li J. Melatonin attenuates colistin-induced nephrotoxicity in rats. Antimicrob Agents Chemother. 2011;55(9):4044\u20139.","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"773_CR31","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1007\/s00134-010-2038-7","volume":"37","author":"E Ozyilmaz","year":"2010","unstructured":"Ozyilmaz E, Ebinc FA, Derici U, et al. Could nephrotoxicity due to colistin be ameliorated with the use of N-acetylcysteine? Intensive Care Med. 2010;37(1):141\u20136.","journal-title":"Intensive Care Med"},{"issue":"2","key":"773_CR32","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1093\/jac\/dkr483","volume":"67","author":"JM Yousef","year":"2012","unstructured":"Yousef JM, Chen G, Hill PA, Nation RL, Li J. Ascorbic acid protects against the nephrotoxicity and apoptosis caused by colistin and affects its pharmacokinetics. J Antimicrob Chemother. 2012;67(2):452\u20139.","journal-title":"J Antimicrob Chemother"},{"issue":"9","key":"773_CR33","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1086\/429323","volume":"40","author":"ME Falagas","year":"2005","unstructured":"Falagas ME, Kasiakou SK. Colistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections. Clin Infect Dis. 2005;40(9):1333\u201341.","journal-title":"Clin Infect Dis"},{"issue":"1","key":"773_CR34","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/0002-9343(88)90501-3","volume":"85","author":"TK Desai","year":"1988","unstructured":"Desai TK, Tsang TK. Aminoglycoside nephrotoxicity in obstructive jaundice. Am J Med. 1988;85(1):47\u201350.","journal-title":"Am J Med"},{"issue":"7","key":"773_CR35","doi-asserted-by":"publisher","first-page":"2887","DOI":"10.1128\/AAC.01430-08","volume":"53","author":"JF Oliveira","year":"2009","unstructured":"Oliveira JF, Silva JA, Barbieri CD, Oliveira GM, Zanetta DM, Burdmann EA. Prevalence and risk factors for aminoglycoside nephrotoxicity in intensive care units. Antimicrob Agents Chemother. 2009;53(7):2887\u201391.","journal-title":"Antimicrob Agents Chemother"},{"issue":"12","key":"773_CR36","doi-asserted-by":"publisher","first-page":"2645","DOI":"10.1093\/jac\/dkq360","volume":"65","author":"P Rattanaumpawan","year":"2010","unstructured":"Rattanaumpawan P, Lorsutthitham J, Ungprasert P, Angkasekwinai N, Thamlikitkul V. Randomized controlled trial of nebulized colistimethate sodium as adjunctive therapy of ventilator-associated pneumonia caused by gram-negative bacteria. J Antimicrob Chemother. 2010;65(12):2645\u20139.","journal-title":"J Antimicrob Chemother"},{"issue":"6","key":"773_CR37","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1016\/j.jinf.2008.04.002","volume":"56","author":"AP Betrosian","year":"2008","unstructured":"Betrosian AP, Frantzeskaki F, Xanthaki A, Douzinas EE. Efficacy and safety of high-dose ampicillin\/sulbactam vs. colistin as monotherapy for the treatment of multidrug resistant Acinetobacter baumannii ventilator-associated pneumonia. J Infect. 2008;56(6):432\u20136.","journal-title":"J Infect"},{"issue":"8","key":"773_CR38","doi-asserted-by":"publisher","first-page":"1058","DOI":"10.1007\/s00134-005-2691-4","volume":"31","author":"R Reina","year":"2005","unstructured":"Reina R, Estenssoro E, S\u00e1enz G, et al. Safety and efficacy of colistin in Acinetobacter and Pseudomonas infections: a prospective cohort study. Intensive Care Med. 2005;31(8):1058\u201365.","journal-title":"Intensive Care Med"},{"issue":"2","key":"773_CR39","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1183\/09031936.00156906","volume":"30","author":"FG Rios","year":"2007","unstructured":"Rios FG, Luna CM, Maskin B, et al. Ventilator-associated pneumonia due to colistin susceptible-only microorganisms. Eur Respir J. 2007;30(2):307\u201313.","journal-title":"Eur Respir J"}],"container-title":["Wiener klinische Wochenschrift"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00508-015-0773-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00508-015-0773-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00508-015-0773-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00508-015-0773-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T18:03:32Z","timestamp":1589479412000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00508-015-0773-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,28]]},"references-count":39,"journal-issue":{"issue":"S8","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["773"],"URL":"https:\/\/doi.org\/10.1007\/s00508-015-0773-z","relation":{},"ISSN":["0043-5325","1613-7671"],"issn-type":[{"value":"0043-5325","type":"print"},{"value":"1613-7671","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,28]]},"assertion":[{"value":"31 May 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 February 2015","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2015","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}