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Although advocated as an aid to smoking cessation, there is increasing evidence of harm not just to the respiratory system, but to all other organs in the body. To give a\u00a0clearer picture on how e\u2011cigarettes can affect our health, we gathered an overview of the literature on the various health effects of e\u2011cigarettes and categorized them into how they specifically affect organ systems.<\/jats:p>\n                <jats:p>E\u2011cigarette exposure has produced a\u00a0range of stress and inflammatory reactions in the pulmonary system, including shortness of breath, coughing, wheezing, bronchial and pulmonary irritations, and impaired pulmonary function. In the oral and gastrointestinal system, gingival inflammation, sore throat, nausea, vomiting, and diarrhea have been reported. Increased tachycardia and blood pressure were reported reactions in the cardiovascular system. In the neurological system headaches, irritability, anxiety, dependence and insomnia were observed. Other effects included ocular irritation, contact dermatitis, acute renal insufficiency, toxicity and potential carcinogenicity. Nevertheless, studies have found improvements in time-based memory and nicotine withdrawal associated with the cessation of conventional cigarette smoking and switching to e\u2011cigarette use. Also, toxic and carcinogenic metabolites were reportedly lower in e\u2011cigarette smokers than in conventional cigarette smokers.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>A\u00a0growing number of studies are showing the adverse effects caused by e\u2011cigarettes on all human organ systems. Further research on the chemical components, the diverse flavors, and the long-term effects on active and passive users are needed to clarify the implications of e\u2011cigarette use on individual and public health.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00508-020-01711-z","type":"journal-article","created":{"date-parts":[[2020,7,20]],"date-time":"2020-07-20T07:03:33Z","timestamp":1595228613000},"page":"1020-1027","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":66,"title":["Health effects of electronic cigarette (e\u2011cigarette) use on organ systems and its implications for public health"],"prefix":"10.1007","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0647-1105","authenticated-orcid":false,"given":"Radhika","family":"Seiler-Ramadas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabell","family":"Sandner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Haider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Grabovac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas Ernst","family":"Dorner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,7,20]]},"reference":[{"issue":"1","key":"1711_CR1","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1586\/ers.11.92","volume":"6","author":"P Caponnetto","year":"2014","unstructured":"Caponnetto\u00a0P, et\u00a0al. 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