{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T20:46:29Z","timestamp":1785357989881,"version":"3.55.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"7-8","license":[{"start":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T00:00:00Z","timestamp":1607472000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T00:00:00Z","timestamp":1607472000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Wien Klin Wochenschr"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1007\/s00508-020-01780-0","type":"journal-article","created":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T10:07:30Z","timestamp":1607508450000},"page":"292-297","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Effect of early oseltamivir on outpatients without hypoxia with suspected COVID-19"],"prefix":"10.1007","volume":"133","author":[{"given":"Satoru","family":"Chiba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,12,9]]},"reference":[{"key":"1780_CR1","doi-asserted-by":"publisher","first-page":"105924","DOI":"10.1016\/j.ijantimicag.2020.105924","volume":"55","author":"CC Lai","year":"2020","unstructured":"Lai\u00a0CC, Shih\u00a0TP, Ko\u00a0WC, Tang\u00a0HJ, Hsueh\u00a0PR. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): the epidemic and the challenges. Int J Antimicrob Agents. 2020;55:105924.","journal-title":"Int J Antimicrob Agents"},{"key":"1780_CR2","doi-asserted-by":"publisher","first-page":"105948","DOI":"10.1016\/j.ijantimicag.2020.105948","volume":"19","author":"LS Wang","year":"2020","unstructured":"Wang\u00a0LS, Wang\u00a0YR, Ye\u00a0DW, Liu\u00a0QQ. A review of the 2019 Novel Coronavirus (COVID-19) based on current evidence. Int J Antimicrob Agents. 2020;19:105948.","journal-title":"Int J Antimicrob Agents"},{"key":"1780_CR3","unstructured":"WHO. Director-General\u2019s opening remarks at the media briefing on COVID-19\u201411 March. 2020. https:\/\/www.who.int\/director-general\/speeches\/detail\/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020."},{"issue":"13","key":"1780_CR4","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1001\/jama.2020.2648","volume":"323","author":"Z Wu","year":"2020","unstructured":"Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a\u00a0report of 72 314\u00a0cases from the Chinese Center for Disease Control and Prevention. JAMA. 2020;323(13):1239\u201342.","journal-title":"JAMA"},{"issue":"3","key":"1780_CR5","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1038\/d41573-020-00016-0","volume":"19","author":"L Guangdi","year":"2020","unstructured":"Guangdi\u00a0L, De Clercq\u00a0E. Therapeutic options for the 2019 novel coronavirus (2019-nCoV). Nat Rev Drug Discov. 2020;19(3):149\u201350.","journal-title":"Nat Rev Drug Discov"},{"issue":"4","key":"1780_CR6","first-page":"9","volume":"53","author":"RA Khamitov","year":"2008","unstructured":"Khamitov\u00a0RA, Loginova\u00a0SLA, Shchukina\u00a0VN, Borisevich\u00a0SV, Maksimov\u00a0VA, Shuster\u00a0AM. Antiviral activity of arbidol and its derivatives against the pathogen of severe acute respiratory syndrome in the cell cultures [in Russian. Vopr Virusol. 2008;53(4):9\u201313.","journal-title":"Vopr Virusol"},{"key":"1780_CR7","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.tmaid.2017.10.004","volume":"20","author":"JA Al-Tawfiq","year":"2017","unstructured":"Al-Tawfiq\u00a0JA, Rabaan\u00a0AA, Hinedi\u00a0K. Influenza is more common than Middle East Respiratory Syndrome Coronavirus (MERS-CoV) among hospitalized adult Saudi patients. Travel Med Infect Dis. 2017;20:56\u201360.","journal-title":"Travel Med Infect Dis"},{"issue":"11","key":"1780_CR8","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1001\/jama.2020.1585","volume":"323","author":"D Wang","year":"2020","unstructured":"Wang\u00a0D, Hu\u00a0B, Hu\u00a0C, Zhu\u00a0F, Liu\u00a0X, Zhang\u00a0J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel Coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323(11):1061\u20139.","journal-title":"China. JAMA."},{"key":"1780_CR9","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1111\/irv.12358","volume":"10","author":"T Yamanaka","year":"2016","unstructured":"Yamanaka\u00a0T, Nemoto\u00a0M, Bannai\u00a0H, Tsujimura\u00a0K, Kondo\u00a0T, Matsumura\u00a0T, et al. Evaluation of twenty-two rapid antigen detection tests in the diagnosis of Equine Influenza caused by viruses of H3N8 subtype. Influenza Other Respir Viruses. 2016;10:127\u201333.","journal-title":"Influenza Other Respir Viruses"},{"key":"1780_CR10","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1093\/jac\/dkg007","volume":"51","author":"FY Aoki","year":"2003","unstructured":"IMPACT Study Group, Aoki\u00a0FY, Macleod\u00a0MD, Paggiaro\u00a0P, et\u00a0al. Early administration of oral oseltamivir increases the benefits of influenza treatment. J\u00a0Antimicrob Chemother. 2003;51:123\u20139.","journal-title":"J Antimicrob Chemother"},{"issue":"5","key":"1780_CR11","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1016\/j.jinf.2020.03.004","volume":"80","author":"J Chen","year":"2020","unstructured":"Chen\u00a0J, Qi\u00a0T, Liu\u00a0L, Ling\u00a0Y, Qian\u00a0Z, Li\u00a0T, et al. Clinical progression of patients with COVID-19 in Shanghai, China. J\u00a0Infect. 2020;80(5):e1\u2013e6.","journal-title":"J Infect"},{"issue":"1","key":"1780_CR12","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1111\/bcpt.12058","volume":"113","author":"H Ono","year":"2013","unstructured":"Ono\u00a0H, Iwajima\u00a0Y, Nagano\u00a0Y, Chazono\u00a0K, Maeda\u00a0Y, Ohsawa\u00a0M, et al. Reduction in sympathetic nerve activity as a\u00a0possible mechanism for the hypothermic effect of oseltamivir, an anti-influenza virus drug, in normal mice. Basic Clin Pharmacol Toxicol. 2013;113(1):25\u201330.","journal-title":"Basic Clin Pharmacol Toxicol"},{"issue":"4","key":"1780_CR13","first-page":"e7560","volume":"12","author":"P Kakodkar","year":"2020","unstructured":"Kakodkar\u00a0P, Kaka\u00a0N, Baig\u00a0MN. A comprehensive literature review on the clinical presentation, and management of the pandemic Coronavirus disease 2019 (COVID-19). Cureus. 2020;12(4):e7560.","journal-title":"Cureus"},{"key":"1780_CR14","unstructured":"Some Drugs for COVID-19, Med Lett Drugs Ther 2020 Apr 6;62(1595):49\u201350."},{"issue":"696","key":"1780_CR15","doi-asserted-by":"publisher","first-page":"e444","DOI":"10.3399\/bjgp20X711941","volume":"70","author":"S Coenen","year":"2020","unstructured":"Coenen\u00a0S, van der Velden\u00a0AW, Cianci\u00a0D, Goossens\u00a0H, Bongard\u00a0E, Saville\u00a0BR, et al. Oseltamivir for coronavirus illness: post-hoc exploratory analysis of an open-label, pragmatic, randomised controlled trial in European primary care from 2016 to 2018. Br J Gen Pract. 2020;70(696):e444\u2013e9.","journal-title":"Br J Gen Pract"},{"issue":"6","key":"1780_CR16","doi-asserted-by":"publisher","first-page":"1248","DOI":"10.1002\/ptr.6614","volume":"34","author":"JK Patra","year":"2020","unstructured":"Patra\u00a0JK, Das\u00a0G, Bose\u00a0S, Banerjee\u00a0S, Vishnuprasad\u00a0CN, Del Pilar Rodriguez-Torres\u00a0M, et al. Star anise (Illicium verum): chemical compounds, antiviral properties, and clinical relevance. Phytother Res. 2020;34(6):1248\u201367.","journal-title":"Phytother Res"},{"issue":"10223","key":"1780_CR17","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/S0140-6736(20)30211-7","volume":"395","author":"N Chen","year":"2020","unstructured":"Chen\u00a0N, Zhou\u00a0M, Dong\u00a0X, Qu\u00a0J, Gong\u00a0F, Han\u00a0Y, et\u00a0al. Epidemiological\u00a0and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a\u00a0descriptive study. Lancet. 2020;395(10223):507\u201313.","journal-title":"Lancet"},{"issue":"39","key":"1780_CR18","doi-asserted-by":"publisher","first-page":"16416","DOI":"10.1073\/pnas.1111179108","volume":"108","author":"ZM Sheng","year":"2011","unstructured":"Sheng\u00a0ZM, Chertow\u00a0DS, Ambroggio\u00a0X, McCall\u00a0S, Przygodzki\u00a0RM, Cunningham\u00a0RE, et\u00a0al. Autopsy series of 68 cases dying before and during the 1918 influenza pandemic peak. Proc Natl Acad Sci U S\u00a0A. 2011;108(39):16416\u201321.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"1780_CR19","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1186\/s12974-019-1538-9","volume":"16","author":"M Zusso","year":"2019","unstructured":"Zusso\u00a0M, Lunardi\u00a0V, Franceschini\u00a0D, Pagetta\u00a0A, Lo\u00a0R, Stifani\u00a0S, et al. Ciprofloxacin and levofloxacin attenuate microglia inflammatory response via TLR4\/NF-kB pathway. J\u00a0Neuroinflammation. 2019;16(1):148.","journal-title":"J Neuroinflammation"}],"container-title":["Wiener klinische Wochenschrift"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00508-020-01780-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00508-020-01780-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00508-020-01780-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,23]],"date-time":"2021-04-23T02:24:25Z","timestamp":1619144665000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00508-020-01780-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,9]]},"references-count":19,"journal-issue":{"issue":"7-8","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["1780"],"URL":"https:\/\/doi.org\/10.1007\/s00508-020-01780-0","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-34210\/v1","asserted-by":"object"},{"id-type":"doi","id":"10.21203\/rs.3.rs-33046\/v1","asserted-by":"object"}]},"ISSN":["0043-5325","1613-7671"],"issn-type":[{"value":"0043-5325","type":"print"},{"value":"1613-7671","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,9]]},"assertion":[{"value":"10 August 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 November 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical guidelines"}},{"value":"S.\u00a0Chiba declares that he has no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the Ethics in Research Committee of Sapporo Suzuki Hospital (No. 2020-001, 14 February 2020) and the procedures were in accordance with institutional guidelines. Verbal informed consent was obtained from each study patient. Before analyzing the data all identifiable information was deleted and specific individuals cannot be identified by these data. Therefore, this was approved by the ethics committee.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}