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Except for one participant with a\u00a0pre-existing diagnosis of rheumatoid arthritis, all other participants were previously healthy. We determined anti-viral binding antibodies at 2\u201310\u00a0weeks, 3\u00a0months, and 6\u00a0months after disease onset as well as neutralizing antibodies at 6\u00a0months. Two binding antibody assays were used, targeting the S1 subunit of the spike protein, and the receptor binding domain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All participants fully recovered spontaneously except for one who had persisting hyposmia. Antibodies to the receptor binding domain persisted for 6\u00a0months in all cases with a\u00a0slight increase of titers, whereas antibodies to S1 dropped below the cut-off point in 2\u00a0participants and showed a\u00a0minimal decrease on average, mainly at month\u00a03 of follow-up in males; however, neutralizing antibodies were detected in all samples at 6 months of follow-up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There is a\u00a0stable and persisting antibody response against acute respiratory syndrome coronavirus\u00a02 at 6\u00a0months after infection. Neutralizing antibodies confirm virus specificity. As the number of coronavirus disease 2019 convalescent cases is increasing sharply, antibody testing should be implemented to identify immunized individuals. 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