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A\u00a0comparison of medical parameters between survivors and non-survivors, as well as to published literature was conducted.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>During the observational period 66\u00a0patients were diagnosed with congenital diaphragmatic hernia. Overall survival was 84.6%. Left-sided hernia occurred in 51\u00a0patients (78.5%) with a\u00a0mortality of 7.8%. In comparison, right-sided hernia occurred less frequently (<jats:italic>n<\/jats:italic>\u202f=\u200912) but showed a higher mortality (33.3%, <jats:italic>p<\/jats:italic>\u202f=\u20090.000). Critically instable patients were provided with venoarterial extracorporeal membrane oxygenation (ECMO, 32.3%, <jats:italic>n<\/jats:italic>\u202f=\u200921). Survival rate among these patients was 66.7%. Right-sided hernia, treatment with inhaled nitric oxide (iNO) over 15\u00a0days and the use of ECMO over 10\u00a0days were significant risk factors for mortality.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The survival rate in this cohort is comparable to the current literature. Parameters such as the side of the diaphragmatic defect, duration of ECMO and inhaled nitric oxide were assessed as mortality risk factors. This analysis of patients with congenital diaphragmatic hernia enhances understanding of risk factors for mortality, helping to improve management and enabling further evaluation in prospective clinical trials.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00508-021-01843-w","type":"journal-article","created":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T11:02:28Z","timestamp":1617102148000},"page":"674-679","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Risk factors for mortality in infants with congenital diaphragmatic hernia: a\u00a0single center experience"],"prefix":"10.1007","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5517-9381","authenticated-orcid":false,"given":"Jennifer Bettina","family":"Brandt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Werther","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Groth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"K\u00fcng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johann","family":"Golej","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelika","family":"Berger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,30]]},"reference":[{"issue":"4","key":"1843_CR1","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1007\/s00431-008-0904-x","volume":"168","author":"AS de Buys Roessingh","year":"2009","unstructured":"de Buys Roessingh\u00a0AS, Dinh-Xuan\u00a0AT. 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