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Patients were divided into groups according to visual improvement after surgical treatment (yes\/no). Following clinical parameters were compared between groups: perioperative steroid use, evidence of optic nerve affection in preoperative neuroimaging, additional optic nerve sheath incision, surgery delay and preoperative C-reactive protein (CRP) levels. Further subgroups analyses were conducted based on etiology (trauma\/tumor).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Among 32 included cases, 16\u00a0patients (50%) reported visual improvement after endoscopic optic nerve decompression. There was no significant difference in visual improvement between etiology subgroups (trauma: <jats:italic>n<\/jats:italic>\u202f=\u20099\/20 (45%) vs. tumor: <jats:italic>n<\/jats:italic>\u202f=\u20097\/12 (58.3%), <jats:italic>p<\/jats:italic>\u202f=\u20090.465). Tumor subgroup patients with visual improvement had a\u00a0significantly higher prevalence of optic nerve affection in preoperative neuroimaging than those without visual improvement (<jats:italic>p<\/jats:italic>\u202f=\u20090.018, \u03c6\u202f=\u20090.683). Perioperative steroid administration was negatively associated with visual outcome (<jats:italic>p<\/jats:italic>\u202f=\u20090.034, \u03c6\u202f=\u20090.375). Nerve sheath incision, surgery delay and preoperative CRP levels did not have a\u00a0significant impact on visual outcome (<jats:italic>p<\/jats:italic>\u202f&gt;\u20090.05).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Radiological findings can help as an indicator for surgical treatment since an affected optic nerve in preoperative neuroimaging resulted in better visual outcome after surgery. The use of steroids should be considered more carefully since it did not show any beneficial effect.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00508-021-01915-x","type":"journal-article","created":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T12:03:49Z","timestamp":1627992229000},"page":"185-194","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Optic nerve injury in preoperative imaging is associated with visual improvement outcome in endoscopic optic nerve decompression"],"prefix":"10.1007","volume":"134","author":[{"given":"Isabella","family":"Leitner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2530-9931","authenticated-orcid":false,"given":"Alexandros","family":"Andrianakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Verena","family":"Gellner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Kiss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damianos","family":"Andrianakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter Valentin","family":"Tomazic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,8,3]]},"reference":[{"key":"1915_CR1","first-page":"233","volume":"1","author":"R Behbehani","year":"2007","unstructured":"Behbehani\u00a0R. 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