{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T05:35:37Z","timestamp":1790919337698,"version":"4.1.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"11-12","license":[{"start":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T00:00:00Z","timestamp":1646784000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T00:00:00Z","timestamp":1646784000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100010109","name":"Medical University of Graz","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100010109","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Wien Klin Wochenschr"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>The number of dialysis patients is steadily increasing. Associated comorbidities include impaired bone and mineral metabolism, termed chronic kidney disease-mineral and bone disorder (CKD-MBD), leading to a\u00a0high fracture risk, increased morbidity and mortality and impaired quality of life. While the bone density is assessed with dual-energy X\u2011ray absorptiometry (DXA), the trabecular bone score (TBS) captures the image texture as a\u00a0potential index of skeletal microarchitecture. The aim of this study was to evaluate the clinical relevance of DXA and TBS in dialysis patients with and without prevalent fractures.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Bone disorders were evaluated in 82\u00a0dialysis patients (37% female) at the University Hospital of Graz, Austria, by DXA including the assessment of the TBS based on a\u00a0patient interview and the local routine patient database software. The patient cohort was stratified by having sustained a\u00a0fragility fracture in the past or not. Descriptive statistics, t\u2011tests for continuous variables and \u03c7<jats:sup>2<\/jats:sup>-tests for nominal variables including results of DXA and TBS were performed to compare these groups considering the dialysis modality and duration as well as the number of kidney transplantations.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Of the 82 patients, 32 (39%) had a\u00a0positive history of fractures. There was a\u00a0significant association between dialysis duration and fracture prevalence (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.05) as well as musculoskeletal pain (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.01). No significant correlation between DXA\/TBS parameters and musculoskeletal pain could be established. The DXA scores did not correlate with fracture prevalence with the exception of DXA radius measurements; however, fracture prevalence significantly correlated inversely with TBS (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The use of DXA has a\u00a0limited role in fracture prediction in dialysis patients; however, the TBS seems to add information as an additional tool for fracture risk estimation in this patient population.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00508-022-02011-4","type":"journal-article","created":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T09:02:47Z","timestamp":1646816567000},"page":"442-448","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Usefulness of the trabecular bone score in maintenance dialysis patients"],"prefix":"10.1007","volume":"134","author":[{"given":"Oliver","family":"Malle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Bergthaler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Krisper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Amrein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans Peter","family":"Dimai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander H.","family":"Kirsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander R.","family":"Rosenkranz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Pieber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Obermayer-Pietsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrid","family":"Fahrleitner-Pammer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,9]]},"reference":[{"issue":"1","key":"2011_CR1","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/BF03350919","volume":"27","author":"L Dalle Carbonare","year":"2004","unstructured":"Dalle Carbonare\u00a0L, Giannini\u00a0S. 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