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Hybrid imaging by positron emission tomography and computed tomography (PET\/CT) is a\u00a0highly relevant imaging modality for diagnostics and disease surveillance but may be associated with a\u00a0significant amount of radiation dose especially in patients with complications.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Objective<\/jats:title>\n                <jats:p>The aim of this retrospective analysis was to compare the image quality and impact of hybrid imaging methods PET\/CT and PET\/MRI on the potential for dose reduction.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This retrospective single-center study included a\u00a0cohort of 32\u00a0patients who were referred to PET\/MRI for the evaluation of LVV, including graft infections and fever of unknown origin. This cohort was compared to a\u00a0similar cohort of 37\u00a0patients who were examined with PET\/CT in the same period. Mean radiation dose as well as image quality to establish a\u00a0diagnosis were compared between the groups.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The mean radiation dose applied in PET\/MRI was significantly lower when compared to PET\/CT (mean 6.6 mSV vs. 31.7 mSV; <jats:italic>p<\/jats:italic>\u202f&lt;\u20090.001). This effect was based on the partially multiphasic CT protocols. At the same time, diagnostic image quality using a\u00a04-point scale showed similar results for both imaging modalities in the work-up of LVV.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>With PET\/MRI, the radiation exposure can be significantly reduced with similar image quality and diagnostic impact. Patients with LVV have a\u00a0higher risk of receiving a\u00a0clinically relevant cumulative effective dose (CED) and PET\/MRI should be made available to them.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00508-024-02336-2","type":"journal-article","created":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T15:02:11Z","timestamp":1709910131000},"page":"627-635","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Hybrid PET\/MRI of large vessel vasculitis"],"prefix":"10.1007","volume":"136","author":[{"given":"Johanna-Felicia","family":"Brauner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sazan","family":"Rasul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominik","family":"Berzaczy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2573-9426","authenticated-orcid":false,"given":"Daniela","family":"Beitzke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Wollenweber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3179-3827","authenticated-orcid":false,"given":"Dietrich","family":"Beitzke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,3,8]]},"reference":[{"key":"2336_CR1","first-page":"143","volume-title":"Large vessel vasculitis: Is it more common than usually assumed? 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