{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T22:10:37Z","timestamp":1771971037435,"version":"3.50.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"19-20","license":[{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100010109","name":"Medical University of Graz","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100010109","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Wien Klin Wochenschr"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Summary<\/jats:title>\n          <jats:sec>\n            <jats:title>Purpose<\/jats:title>\n            <jats:p>Bone transport nails (BTN) are increasingly being used for defect reconstruction in orthopedic surgery, including orthopedic oncology. Herein, we report on preliminary outcomes in three adult sarcoma patients undergoing bone defect reconstruction of the lower limbs with a\u00a0BTN.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>In this study three patients were retrospectively included; ID1\u00a0male, 18\u00a0years, Ewing\u2019s sarcoma of the right tibial diaphysis; ID2\u00a0female, 30\u00a0years, G2 periosteal osteosarcoma of the left femoral diaphysis; ID3\u00a0female, 28\u00a0years, epithelioid malignant peripheral nerve sheath tumor (MPNST) originating from the right proximal tibial metaphysis. All patients had been treated at a\u00a0university hospital for primary sarcomas of the lower limbs and underwent defect reconstruction with a\u00a0BTN (Precice\u00ae System, NuVasive GmbH, Globus Medical, Audubon, PA, USA).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Bone defect lengths were 8.5\u202fcm, 14.1\u202fcm and 14.4\u202fcm, respectively. Bone transport time amounted to 5.3 months, 9.1 months and 10.3 months, and time to bony consolidation to 9.1 months, 12.3 months and 14.7 months, respectively (in ID1 and ID3 partially). Patient ID1 required revision surgery for a\u00a0wire breakage (used for two-level transport) and one screw avulsion. Patient ID2 developed a\u00a0peri-implant infection that was successfully treated with prolonged antibiotics. In ID3, an occult intraoperative distal femoral fracture was initially treated conservatively. A\u00a0consecutive varus\/flexion deformity and residual ipsilateral limb length discrepancy was addressed via distal femoral osteotomy and retrograde femoral growing nail implantation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>The Precice\u00ae BTN can be used for reconstruction of diaphyseal long bone defects in patients with primary malignant tumors; however, candidate patients have to be thoroughly counselled regarding the prolonged immobilization and partial weight-bearing period associated with the lengthening procedure as well as risk for complications and revision surgery.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00508-025-02527-5","type":"journal-article","created":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T14:53:47Z","timestamp":1743864827000},"page":"654-660","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Bone transport nails for reconstruction of lower limb diaphyseal defects in patients with bone sarcomas"],"prefix":"10.1007","volume":"137","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1021-0899","authenticated-orcid":false,"given":"Maria Anna","family":"Smolle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Z\u00f6tsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimosthenis","family":"Andreou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marisa","family":"Valentini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Leithner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Lanz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,4,4]]},"reference":[{"issue":"1","key":"2527_CR1","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1302\/0301-620X.105B1.BJJ-2022-0722.R2","volume":"105-b","author":"M San-Juli\u00e1n","year":"2023","unstructured":"San-Juli\u00e1n\u00a0M, G\u00f3mez-\u00c1lvarez\u00a0J, Idoate\u00a0M, Aquerreta\u00a0JD, V\u00e1zquez-Garc\u00eda\u00a0B, Lamo-Espinosa\u00a0JM. 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S.\u00a0Z\u00f6tsch has received payment\/honoraria for lectures by Nuvasive, outside of the submitted work. D.\u00a0Andreou reports the receipt of honoraria from PharmaMar, unrelated to this work. M.\u00a0Valentini has received travel support by Alphamed, outside of the submitted work. A.\u00a0Leithner reports institutional educational grants by Alphamed, Medacta and Johnson&Johnson outside of the submitted work. P.\u00a0Lanz has received payment\/honoraria by Nuvasive and has a\u00a0consulting contract with Nuvasive, outside of the submitted work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was carried out in accordance with national guidelines and the ethical standards by the Declaration of Helsinki. This study was approved by the local institutional review board (IRB-number: 1298\/2024). Given the retrospective design of the study, written informed consent to participate was waived by the local institutional review board.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}