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This meta-analysis and systematic review aimed to assess the effectiveness of burnout prevention programs and to evaluate whether one approach is superior to other programs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients, material and methods<\/jats:title>\n                    <jats:p>The methods were based on the Cochrane Handbook of Systematic Reviews. We searched the literature in five medical databases from October 2019 to June 2022. We included randomized controlled trials that examined the effect of burnout prevention programs on physicians.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A\u00a0total of 22\u00a0studies were included in our analysis, with 20\u00a0studies targeting individual interventions and 2\u00a0studies targeting structural interventions. Mindfulness-based stress reduction (MBSR) or similar programs were the most common interventions. The main analysis showed a\u00a0significant reduction of burnout in the intervention groups with an standardised mean difference (SMD) of \u22120.32 (95% confidence interval, CI: \u22120.41 to \u22120.22), which suggests a\u00a0small to moderate effect. MBSR did not appear superior to other interventions in the subgroup analysis SMD \u22120.25 (95% CI: \u22120.48 to \u22120.02) versus SMD \u22120.61 (95% CI: \u22121.19 to 0.03).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This analysis shows that individual burnout prevention programs may reduce burnout rates in physicians; however, the effect was relatively small. The effect was reduced even further when removing studies causing severe heterogeneity and those with a\u00a0high risk of bias. Future research programs should focus on structural programs that address the lack of mentoring, rising administrative tasks, or long working hours, which may be more effective in reducing burnout in physicians.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00508-025-02601-y","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T07:07:26Z","timestamp":1762758446000},"page":"167-178","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Prevention of burnout syndrome in physicians: a\u00a0systematic review and meta-analysis"],"prefix":"10.1007","volume":"138","author":[{"given":"Lea","family":"Krebs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1669-2334","authenticated-orcid":false,"given":"Jasmin","family":"Arrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,10]]},"reference":[{"key":"2601_CR1","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1146\/annurev.psych.52.1.397","volume":"52","author":"C Maslach","year":"2001","unstructured":"Maslach\u00a0C, Schaufeli\u00a0WB, Leiter\u00a0MP. 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