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Es besteht breiter Konsens, dass eine effiziente Diabetes-Pr\u00e4vention und Therapie in den meisten F\u00e4llen auch von einer Modifikation des Lebensstils begleitet sein muss. Ziele der F\u00f6rderung der k\u00f6rperlichen Aktivit\u00e4t sind zun\u00e4chst das Training des Herz-Kreislauf-Systems, Kr\u00e4ftigung der Muskulatur, Steigerung des Energieumsatzes und die Reduktion von Inaktivit\u00e4t. F\u00fcr einen substanziellen gesundheitlichen Nutzen sind w\u00f6chentlich mindestens 150\u202fmin aerobe k\u00f6rperliche Aktivit\u00e4t mit mittlerer oder 75\u202fmin h\u00f6herer Intensit\u00e4t und zus\u00e4tzlich muskelkr\u00e4ftigende Bewegungen erforderlich. Das Ausma\u00df des positiven Effektes von Bewegung steht in direktem Verh\u00e4ltnis zum Grad der erreichten kardiorespiratorischen Fitness und kann nur durch entsprechendes Training aufrechterhalten werden. K\u00f6rperliches Training ist in jedem Alter f\u00fcr beide Geschlechter wirksam und effektiv. Durch die Reduktion der Insulinresistenz und funktionelle Verbesserung der Insulinsekretion hat k\u00f6rperliches Training positiven Einfluss auf die Glyk\u00e4mie, und zus\u00e4tzlich wird das kardiovaskul\u00e4re Risiko gesenkt. Im Speziellen hat k\u00f6rperliches Training nicht nur einen positiven Einfluss auf die Glyk\u00e4mie, indem es die Insulinresistenz verringert und die funktionelle Insulinsekretion verbessert, sondern es kann auch das kardiovaskul\u00e4re Risiko senken. K\u00f6rperliche Inaktivit\u00e4t gilt unabh\u00e4ngig von Art und Umfang k\u00f6rperlicher Aktivit\u00e4t als eigenst\u00e4ndiger Risikofaktor. Insbesondere langandauernde sitzende T\u00e4tigkeiten sollten daher vermieden werden.<\/jats:p>","DOI":"10.1007\/s00508-025-02651-2","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T22:12:29Z","timestamp":1779315149000},"page":"142-147","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lebensstil: k\u00f6rperliche Aktivit\u00e4t und Training in der Pr\u00e4vention und Therapie des Typ 2 Diabetes mellitus (Update 2026)","Lifestyle: physical activity and training in the prevention and treatment of type\u00a02 diabetes mellitus (Update 2026)"],"prefix":"10.1007","volume":"138","author":[{"given":"Claudia","family":"Francesconi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Othmar","family":"Moser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raimund","family":"Weitgasser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Lackinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"issue":"25","key":"2651_CR1","doi-asserted-by":"publisher","first-page":"3244","DOI":"10.1161\/CIRCULATIONAHA.109.192521","volume":"119","author":"TH Marwick","year":"2009","unstructured":"Marwick\u00a0TH, Hordern\u00a0MD, Miller\u00a0T, Chyun\u00a0DA, Bertoni\u00a0AG, Blumenthal\u00a0RS, et\u00a0al. 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