{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:04:38Z","timestamp":1784192678790,"version":"3.55.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"13-14","license":[{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["No. 82100715"],"award-info":[{"award-number":["No. 82100715"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the Basic and Applied Basic Research Project of Zhengzhou Science and Technology Bureau","award":["No. 2024ZZJCYJ034"],"award-info":[{"award-number":["No. 2024ZZJCYJ034"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Wien Klin Wochenschr"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1007\/s00508-025-02683-8","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T14:23:19Z","timestamp":1766413399000},"page":"416-426","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy and safety of pleural infusion of elemene in the treatment of peritoneal dialysis complicated with pleuroperitoneal communication"],"prefix":"10.1007","volume":"138","author":[{"given":"Panpan","family":"Cao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kangle","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanghua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenming","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,22]]},"reference":[{"issue":"9818","key":"2683_CR1","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1016\/s0140-6736(12)60033-6","volume":"379","author":"L Zhang","year":"2012","unstructured":"Zhang\u00a0L, Wang\u00a0F, Wang\u00a0L, et\u00a0al. Prevalence of chronic kidney disease in China: a\u00a0cross-sectional survey. Lancet. 2012;379(9818):815\u201322. https:\/\/doi.org\/10.1016\/s0140-6736(12)60033-6.","journal-title":"Lancet"},{"issue":"4","key":"2683_CR2","doi-asserted-by":"publisher","first-page":"e160","DOI":"10.1097\/RLU.0000000000004581","volume":"48","author":"SY Kang","year":"2023","unstructured":"Kang\u00a0SY, Moon\u00a0BS, Yoo\u00a0MY, et\u00a0al. Clinical Impact of SPECT\/CT in Evaluation of Abdominothoracic Fistula. Clin Nucl Med. 2023;48(4):e160\u2013e2. https:\/\/doi.org\/10.1097\/RLU.0000000000004581.","journal-title":"Clin Nucl Med"},{"issue":"12","key":"2683_CR3","doi-asserted-by":"publisher","first-page":"3023","DOI":"10.1681\/asn.2007070796","volume":"18","author":"BB McCormick","year":"2007","unstructured":"McCormick\u00a0BB, Bargman\u00a0JM. Noninfectious complications of peritoneal dialysis: implications for patient and technique survival. J\u00a0Am Soc Nephrol. 2007;18(12):3023\u20135. https:\/\/doi.org\/10.1681\/asn.2007070796.","journal-title":"J Am Soc Nephrol"},{"key":"2683_CR4","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1186\/1752-1947-4-355","volume":"4","author":"Y Cho","year":"2010","unstructured":"Cho\u00a0Y, D\u2019Intini\u00a0V, Ranganathan\u00a0D. Acute hydrothorax complicating peritoneal dialysis: a\u00a0case report. J\u00a0Med Case Rep. 2010;4:355. https:\/\/doi.org\/10.1186\/1752-1947-4-355.","journal-title":"J Med Case Rep"},{"issue":"4","key":"2683_CR5","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1093\/ndt\/gfg042","volume":"18","author":"S Tang","year":"2003","unstructured":"Tang\u00a0S, Chui\u00a0WH, Tang\u00a0AW, et\u00a0al. Video-assisted thoracoscopic talc pleurodesis is effective for maintenance of peritoneal dialysis in acute hydrothorax complicating peritoneal dialysis. Nephrol Dial Transplant. 2003;18(4):804\u20138. https:\/\/doi.org\/10.1093\/ndt\/gfg042.","journal-title":"Nephrol Dial Transplant"},{"issue":"3","key":"2683_CR6","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1177\/089686080702700315","volume":"27","author":"RG Krishnan","year":"2007","unstructured":"Krishnan\u00a0RG, Ognjanovic\u00a0MV, Crosier\u00a0J, et\u00a0al. Acute hydrothorax complicating peritoneal dialysis. Perit Dial Int. 2007;27(3):296\u20139.","journal-title":"Perit Dial Int"},{"issue":"14","key":"2683_CR7","first-page":"1857","volume":"37","author":"WU Huijie","year":"2021","unstructured":"Huijie\u00a0WU, Haiying\u00a0XU, Lingyun\u00a0Z, et\u00a0al. Effect of intracavitary infusion of elemene combined with nedaplatin on clinical efficacy and quality of life of patients with malignant ascites. J\u00a0Pract Med. 2021;37(14):1857\u201360.","journal-title":"J Pract Med"},{"issue":"44","key":"2683_CR8","doi-asserted-by":"publisher","first-page":"e12542","DOI":"10.1097\/MD.0000000000012542","volume":"97","author":"QT Wang","year":"2018","unstructured":"Wang\u00a0QT, Zhang\u00a0ZL, Xiong\u00a0H, et\u00a0al. Evaluation of the efficacy and safety of elemene in treating malignant pleural effusion caused by tumors: A\u00a0PRISMA guided meta-analysis. Med (baltimore). 2018;97(44):e12542. https:\/\/doi.org\/10.1097\/MD.0000000000012542.","journal-title":"Med (baltimore)"},{"issue":"1","key":"2683_CR9","doi-asserted-by":"publisher","first-page":"55","DOI":"10.3760\/cma.j.issn.1001-7097.2020.01.012","volume":"36","author":"X Lan","year":"2020","unstructured":"Lan\u00a0X, Xianming\u00a0W, Meili\u00a0X, et\u00a0al. Intrapleural infusion of elemene for peritoneal dialysis complicating pleuroperitoneal communication: four cases report. Chin J Nephrol. 2020;36(1):55\u20137. https:\/\/doi.org\/10.3760\/cma.j.issn.1001-7097.2020.01.012.","journal-title":"Chin J Nephrol"},{"issue":"1","key":"2683_CR10","doi-asserted-by":"publisher","first-page":"56","DOI":"10.31491\/APT.2025.03.167","volume":"7","author":"R Joshi","year":"2025","unstructured":"Joshi R, Tetgure C, & Shah Y. Effect of dual task training versus analogy training on gait speed and balance in older adults\u2014randomized controlled trial. Aging Pathobiology and Therapeutics. 2025;7(1):56\u201363. https:\/\/doi.org\/10.31491\/APT.2025.03.167","journal-title":"Aging Pathobiology and Therapeutics"},{"issue":"11","key":"2683_CR11","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1001\/jama.1967.03120110125031","volume":"199","author":"SR Edwards","year":"1967","unstructured":"Edwards\u00a0SR, Unger\u00a0AM. Acute hydrothorax\u2014a new complication of peritoneal dialysis. JAMA. 1967;199(11):853\u20135.","journal-title":"JAMA"},{"issue":"1","key":"2683_CR12","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1177\/089686089801800101","volume":"18","author":"R Garcia Ramon","year":"1998","unstructured":"Garcia Ramon\u00a0R, Carrasco\u00a0AM. Hydrothorax in peritoneal dialysis. Perit Dial Int. 1998;18(1):5\u201310.","journal-title":"Perit Dial Int"},{"issue":"1","key":"2683_CR13","doi-asserted-by":"publisher","first-page":"13","DOI":"10.3747\/pdi.2008.00168","volume":"30","author":"LSQ Hydrothorax","year":"2010","unstructured":"Hydrothorax\u00a0LSQ. pleural effusion associated with peritoneal dialysis. Perit Dial Int. 2010;30(1):13\u20138. https:\/\/doi.org\/10.3747\/pdi.2008.00168.","journal-title":"Perit Dial Int"},{"issue":"1","key":"2683_CR14","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1046\/j.1525-139x.2001.00014.x","volume":"14","author":"M Leblanc","year":"2001","unstructured":"Leblanc\u00a0M, Ouimet\u00a0D, Pichette\u00a0V. Dialysate leaks in peritoneal dialysis. Semin Dial. 2001;14(1):50\u20134. https:\/\/doi.org\/10.1046\/j.1525-139x.2001.00014.x.","journal-title":"Semin Dial"},{"issue":"3","key":"2683_CR15","doi-asserted-by":"publisher","first-page":"1212","DOI":"10.1093\/ndt\/gfr393","volume":"27","author":"N Momenin","year":"2012","unstructured":"Momenin\u00a0N, Colletti\u00a0PM, Kaptein\u00a0EM. Low pleural fluid-to-serum glucose gradient indicates pleuroperitoneal communication in peritoneal dialysis patients: presentation of two cases and a\u00a0review of the literature. Nephrol Dial Transplant. 2012;27(3):1212\u20139. https:\/\/doi.org\/10.1093\/ndt\/gfr393.","journal-title":"Nephrol Dial Transplant"},{"issue":"5","key":"2683_CR16","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1111\/j.1525-139X.2011.00859.x","volume":"24","author":"K Tapawan","year":"2011","unstructured":"Tapawan\u00a0K, Chen\u00a0E, Selk\u00a0N, et\u00a0al. A\u00a0large pleural effusion in a\u00a0patient receiving peritoneal dialysis. Semin Dial. 2011;24(5):560\u20133. https:\/\/doi.org\/10.1111\/j.1525-139X.2011.00859.x.","journal-title":"Semin Dial"},{"issue":"11","key":"2683_CR17","doi-asserted-by":"publisher","first-page":"2451","DOI":"10.1093\/ndt\/gfg408","volume":"18","author":"P Mangana","year":"2003","unstructured":"Mangana\u00a0P, Arvanitis\u00a0D, Vlassopoulos\u00a0D. Acute hydrothorax in peritoneal dialysis patients: diagnosis and treatment options. Nephrol Dial Transplant. 2003;18(11):2451. https:\/\/doi.org\/10.1093\/ndt\/gfg408.","journal-title":"Nephrol Dial Transplant"},{"issue":"4","key":"2683_CR18","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1177\/089686080202200416","volume":"22","author":"KM Chow","year":"2002","unstructured":"Chow\u00a0KM, Szeto\u00a0CC, Wong\u00a0TY, et\u00a0al. Hydrothorax complicating peritoneal dialysis: diagnostic value of glucose concentration in pleural fluid aspirate. Perit Dial Int. 2002;22(4):525\u20138.","journal-title":"Perit Dial Int"},{"issue":"10","key":"2683_CR19","doi-asserted-by":"publisher","first-page":"1035","DOI":"10.1093\/ndt\/7.10.1035","volume":"7","author":"R Scanziani","year":"1992","unstructured":"Scanziani\u00a0R, Dozio\u00a0B, Caimi\u00a0F, et\u00a0al. Peritoneography and peritoneal computerized tomography: a\u00a0new approach to non-infectious complications of CAPD. Nephrol Dial Transplant. 1992;7(10):1035\u20138.","journal-title":"Nephrol Dial Transplant"},{"issue":"1","key":"2683_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3760\/cma.j.cn101548-20230927-00067","volume":"7","author":"SZ Zang Yuansheng","year":"2024","unstructured":"Zang Yuansheng\u00a0SZ. Jiao Xiaodong, et\u00a0al. Chinese expert consensus on anti-tumor clinical application of elemene injection. Chin J Metastatic Cancer. 2024;7(1):1\u20139. https:\/\/doi.org\/10.3760\/cma.j.cn101548-20230927-00067.","journal-title":"Chin J Metastatic Cancer"},{"issue":"2","key":"2683_CR21","first-page":"117","volume":"16","author":"B Jiao","year":"2017","unstructured":"Jiao\u00a0B, Rong-bo\u00a0L, Hui\u00a0Z. Value of CT peritoneography in the diagnosis of continuous ambulatory peritoneal dialysis-related. Chin J Blood Purif. 2017;16(2):117\u201320.","journal-title":"Chin J Blood Purif"},{"issue":"1","key":"2683_CR22","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1159\/000506119","volume":"10","author":"CG Ambarsari","year":"2020","unstructured":"Ambarsari\u00a0CG, Bermanshah\u00a0EK, Putra\u00a0MA, et\u00a0al. Effective Management of Peritoneal Dialysis-Associated Hydrothorax in a\u00a0Child: A\u00a0Case Report. Case Rep Nephrol Dial. 2020;10(1):18\u201325. https:\/\/doi.org\/10.1159\/000506119.","journal-title":"Case Rep Nephrol Dial"},{"issue":"6","key":"2683_CR23","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1007\/s00261-008-9468-5","volume":"34","author":"TW Kang","year":"2009","unstructured":"Kang\u00a0TW, Kim\u00a0CK. Pleuroperitoneal communication of peritoneal dialysis demonstrated by multidetector-row CT peritoneography. Abdom Imaging. 2009;34(6):780\u20132. https:\/\/doi.org\/10.1007\/s00261-008-9468-5.","journal-title":"Abdom Imaging"},{"issue":"1","key":"2683_CR24","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/s0003-4975(02)03648-2","volume":"74","author":"SK Mak","year":"2002","unstructured":"Mak\u00a0SK, Nyunt\u00a0K, Wong\u00a0PN, et\u00a0al. Long-term follow-up of thoracoscopic pleurodesis for hydrothorax complicating peritoneal dialysis. Ann Thorac Surg. 2002;74(1):218\u201321. https:\/\/doi.org\/10.1016\/s0003-4975(02)03648-2.","journal-title":"Ann Thorac Surg"},{"issue":"3","key":"2683_CR25","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1046\/j.1440-1843.2001.00327.x","volume":"6","author":"A Brant","year":"2001","unstructured":"Brant\u00a0A, Eaton\u00a0T. Serious complications with talc slurry pleurodesis. Respirology. 2001;6(3):181\u20135. https:\/\/doi.org\/10.1046\/j.1440-1843.2001.00327.x.","journal-title":"Respirology"},{"issue":"11","key":"2683_CR26","first-page":"963","volume":"67","author":"T Tsuchiya","year":"2014","unstructured":"Tsuchiya\u00a0T, Sano\u00a0A, Fukami\u00a0T, et\u00a0al. Video-assisted thoracoscopic surgery for pleuroperitoneal communications as a\u00a0complication of continuous ambulatory peritoneal dialysis( CAPD). Kyobu Geka. 2014;67(11):963\u20136.","journal-title":"Kyobu Geka"},{"issue":"4","key":"2683_CR27","first-page":"91","volume":"36","author":"M Nishina","year":"2011","unstructured":"Nishina\u00a0M, Iwazaki\u00a0M, Koizumi\u00a0M, et\u00a0al. Case of peritoneal dialysis-related acute hydrothorax, which was successfully treated by thoracoscopic surgery, using collagen fleece. Tokai J Exp Clin Med. 2011;36(4):91\u20134.","journal-title":"Tokai J Exp Clin Med"},{"issue":"4","key":"2683_CR28","doi-asserted-by":"publisher","first-page":"A19","DOI":"10.1053\/j.ajkd.2015.02.022","volume":"65","author":"Z Arabi","year":"2015","unstructured":"Arabi\u00a0Z, Porter\u00a0M, Spaeth\u00a0D, et\u00a0al. Hydrothorax as a\u00a0complication of peritoneal dialysis: still a\u00a0cause for treatment failure. Am J Kidney Dis. 2015;65(4):A19.","journal-title":"Am J Kidney Dis"},{"key":"2683_CR29","doi-asserted-by":"publisher","first-page":"213","DOI":"10.3760\/cma.j.issn.0376-2491.2018.03.011","volume":"98","author":"W Huang","year":"2018","unstructured":"Huang\u00a0W, Xu\u00a0Y, Yang\u00a0Z, et\u00a0al. Diagnosis and thoracoscopic treatment for pleuroperitoneal communication complicating peritoneal dialysis. Chung Hua I Hsueh Tsa Chih. 2018;98:213\u20136. https:\/\/doi.org\/10.3760\/cma.j.issn.0376-2491.2018.03.011.","journal-title":"Chung Hua I Hsueh Tsa Chih"},{"issue":"7","key":"2683_CR30","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1093\/ndt\/9.7.832","volume":"9","author":"S Fletcher","year":"1994","unstructured":"Fletcher\u00a0S, Turney\u00a0JH, Brownjohn\u00a0AM. Increased incidence of hydrothorax complicating peritoneal dialysis in patients with adult polycystic kidney disease. Nephrol Dial Transplant. 1994;9(7):832\u20133.","journal-title":"Nephrol Dial Transplant"},{"key":"2683_CR31","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1186\/1471-2407-11-183","volume":"11","author":"J Liu","year":"2011","unstructured":"Liu\u00a0J, Zhang\u00a0Y, Qu\u00a0J, et\u00a0al. beta-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis. Bmc Cancer. 2011;11:183. https:\/\/doi.org\/10.1186\/1471-2407-11-183.","journal-title":"Bmc Cancer"},{"key":"2683_CR32","doi-asserted-by":"publisher","first-page":"571476","DOI":"10.3389\/fonc.2021.571476","volume":"11","author":"H Cai","year":"2021","unstructured":"Cai\u00a0H, Ren\u00a0L, Wang\u00a0Y, et\u00a0al. Beta-Elemene Reduces the Malignancy of Non-Small Cell Lung Cancer by Enhancing C3orf21 Expression. Front Oncol. 2021;11:571476. https:\/\/doi.org\/10.3389\/fonc.2021.571476.","journal-title":"Front Oncol"},{"issue":"09","key":"2683_CR33","doi-asserted-by":"publisher","first-page":"1430","DOI":"10.4268\/cjcmm20130934","volume":"38","author":"X Xiaowei","year":"2013","unstructured":"Xiaowei\u00a0X, Zhengzhong\u00a0Y, Wenhao\u00a0H, et\u00a0al. Meta-analysis on elemene injection combined with cisplatin chemotherapeutics in treatment of non-small cell lung cancer. CJCMM. 2013;38(09):1430\u20137. https:\/\/doi.org\/10.4268\/cjcmm20130934.","journal-title":"CJCMM"}],"container-title":["Wiener klinische Wochenschrift"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00508-025-02683-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00508-025-02683-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00508-025-02683-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T08:24:39Z","timestamp":1784190279000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00508-025-02683-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,22]]},"references-count":33,"journal-issue":{"issue":"13-14","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["2683"],"URL":"https:\/\/doi.org\/10.1007\/s00508-025-02683-8","relation":{},"ISSN":["0043-5325","1613-7671"],"issn-type":[{"value":"0043-5325","type":"print"},{"value":"1613-7671","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,22]]},"assertion":[{"value":"12 June 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"P.\u00a0Cao, K.\u00a0Su, F.\u00a0Li, X.\u00a0Wang, W.\u00a0Yuan, S.\u00a0Lu and D.\u00a0Liu declare that they have no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Medical Ethics Review Committee of the First Affiliated Hospital of Zhengzhou University (No.: 2018-KY-36).","order":3,"name":"Ethics","label":"Ethical standards","group":{"name":"EthicsHeading","label":"Declarations"}}]}}