{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:11:49Z","timestamp":1792782709317,"version":"4.5.0"},"reference-count":5,"publisher":"Springer Science and Business Media LLC","issue":"19-20","license":[{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Medical University of Graz","id":[{"id":"https:\/\/ror.org\/02n0bts35","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Wien Klin Wochenschr"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Amelanotic acral melanoma is an uncommon melanoma subtype often associated with delayed diagnosis due to its nonpigmented and clinically inconspicuous presentation. We report the case of a\u00a061-year-old man presenting with a\u00a0painful erythematous nodule on the plantar aspect of the second toe persisting for 1\u00a0year and initially presumed benign. Histopathological evaluation confirmed acral amelanotic melanoma (pT3a) with micrometastatic sentinel lymph node involvement. The patient underwent partial toe amputation followed by adjuvant immunotherapy with nivolumab. This case underscores the importance of early biopsy of persistent acral lesions to reduce diagnostic delay and improve outcomes.<\/jats:p>","DOI":"10.1007\/s00508-026-02732-w","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T16:08:16Z","timestamp":1773763696000},"page":"642-644","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Masked pressure lesion on the tip of the toe, a\u00a0diagnostic challenge"],"prefix":"10.1007","volume":"138","author":[{"given":"Regina","family":"Fink-Puches","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Irmler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Zarfl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,17]]},"reference":[{"issue":"1","key":"2732_CR1","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1590\/abd1806-4841.20197568","volume":"94","author":"W Deng","year":"2019","unstructured":"Deng\u00a0W, Yu\u00a0R, Cui\u00a0Y, Zheng\u00a0Z. Amelanotic acral melanoma misdiagnosed as verruca plantaris. An Bras Dermatol. 2019;94(1):86\u20138.","journal-title":"An Bras Dermatol"},{"issue":"21","key":"2732_CR2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms252111502","volume":"25","author":"P Misi\u0105g","year":"2024","unstructured":"Misi\u0105g\u00a0P, Molik\u00a0K, Kisielewska\u00a0M, Typek\u00a0P, Skowron\u00a0I, Karwowska\u00a0A, et\u00a0al. Amelanotic Melanoma\u2014Biochemical and Molecular Induction Pathways. Int J Mol Sci. 2024;25(21)11502.","journal-title":"Int J Mol Sci"},{"issue":"5","key":"2732_CR3","doi-asserted-by":"publisher","first-page":"518","DOI":"10.3390\/jpm14050518","volume":"14","author":"F Cassalia","year":"2024","unstructured":"Cassalia\u00a0F, Danese\u00a0A, Cocchi\u00a0E, Danese\u00a0E, Ambrogio\u00a0F, Cazzato\u00a0G, et\u00a0al. Misdiagnosis and Clinical Insights into Acral Amelanotic Melanoma\u2014A Systematic Review. J\u00a0Pers Med. 2024;14(5):518\u2013518.","journal-title":"J Pers Med"},{"issue":"6","key":"2732_CR4","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1097\/01.SAP.0000041481.21471.A9","volume":"50","author":"P Parodi","year":"2003","unstructured":"Parodi\u00a0P, Scott\u00a0CA, De Biasio\u00a0F, Pezzini\u00a0I, Pertoldi\u00a0B, Beltrami\u00a0CA. Desmoplastic Melanoma of the Nail. Ann Plast Surg. 2003;50(6):658\u201362.","journal-title":"Ann Plast Surg"},{"issue":"5","key":"2732_CR5","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1046\/j.1610-0387.2003.02042.x","volume":"1","author":"I Zalaudek","year":"2003","unstructured":"Zalaudek\u00a0I, Argenziano\u00a0G, Kerl\u00a0H, Soyer\u00a0HP, Hofmann-Wellenhof\u00a0R. Amelanotic\/Hypomelanotic Melanoma \u2013 Is Dermatoscopy Useful For Diagnosis?: Amelanotisches\/Hypopigmentiertes Melanom \u2013 Ist die Auflichtmikroskopie hilfreich f\u00fcr die Diagnose? JDDG J Dtsch Dermatol Ges. 2003;1(5):369\u201373. https:\/\/doi.org\/10.1046\/j.1610-0387.2003.02042.x.","journal-title":"JDDG J Dtsch Dermatol Ges"}],"container-title":["Wiener klinische Wochenschrift"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00508-026-02732-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00508-026-02732-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00508-026-02732-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T22:28:37Z","timestamp":1792103317000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00508-026-02732-w"}},"subtitle":["Case report"],"short-title":[],"issued":{"date-parts":[[2026,3,17]]},"references-count":5,"journal-issue":{"issue":"19-20","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["2732"],"URL":"https:\/\/doi.org\/10.1007\/s00508-026-02732-w","relation":{},"ISSN":["0043-5325","1613-7671"],"issn-type":[{"value":"0043-5325","type":"print"},{"value":"1613-7671","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,17]]},"assertion":[{"value":"23 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"R.\u00a0Fink-Puches, L.\u00a0Irmler and M.\u00a0Zarfl declare that they have no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Ethics"}},{"value":"Written informed consent for publication of the clinical details and images was obtained from the patient.","order":2,"name":"Ethics","label":"Patient consent","group":{"name":"EthicsHeading","label":"Ethics"}}]}}