{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T14:03:58Z","timestamp":1776780238989,"version":"3.51.2"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100010109","name":"Medical University of Graz","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100010109","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Wien Klin Wochenschr"],"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Plexiform fibromyxoma is a\u00a0very rare gastrointestinal tumor, usually located in the stomach, predominantly in the antrum region. There are some cases reporting the tumor location in the small intestine, whereas originating from the esophagus has been described only twice up to now. This is the first report of a\u00a0fast growing and symptomatic giant esophageal plexiform fibromyxoma requiring transthoracic esophagectomy and reconstruction by gastric pull-up.<\/jats:p>\n                  <jats:p>A\u00a073-year-old patient was admitted with the clinical symptoms of dysphagia, chest pain, fever and weight loss for at least 2 months. A computed tomography (CT) scan revealed a\u00a0giant mediastinal tumor measuring 11\u202f\u00d7\u20097\u202f\u00d7\u20097\u202fcm with subsequent compression of the esophagus, the trachea and the heart. Endoscopy showed an ulcerated esophagus with signs of necrosis and obstruction of the esophageal lumen. A 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) scan detected a\u00a0massive tracer uptake of this esophageal tumor suggesting malignancy.<\/jats:p>\n                  <jats:p>After discussion in the interdisciplinary tumor board transthoracic esophagectomy and reconstruction by gastric pull-up were performed. The patient fully recovered and was discharged on the 12th\u00a0postoperative day. Contrary to the intraoperative frozen section indicating an esophageal sarcoma the final histopathological examination confirmed a\u00a0giant esophageal plexiform fibromyxoma.<\/jats:p>","DOI":"10.1007\/s00508-026-02740-w","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T13:05:35Z","timestamp":1776776735000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Giant plexiform fibromyxoma of the esophagus"],"prefix":"10.1007","author":[{"given":"Paul","family":"Swatek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8358-4225","authenticated-orcid":false,"given":"Edin","family":"Ahmic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iva","family":"Brcic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iurii","family":"Mykoliuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anton","family":"Busau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrej","family":"Roj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rg","family":"Lindenmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,4,21]]},"reference":[{"issue":"11","key":"2740_CR1","doi-asserted-by":"publisher","first-page":"1624","DOI":"10.1097\/PAS.0b013e3181ae666a","volume":"33","author":"M Miettinen","year":"2009","unstructured":"Miettinen\u00a0M, Makhlouf\u00a0HR, Sobin\u00a0LH, Lasota\u00a0J. Plexiform fibromyxoma: a\u00a0distinctive benign gastric antral neoplasm not to be confused with a\u00a0myxoid GIST. Am J Surg Pathol. 2009;33(11):1624\u201332. https:\/\/doi.org\/10.1097\/PAS.0b013e3181ae666a.","journal-title":"Am J Surg Pathol"},{"issue":"11","key":"2740_CR2","first-page":"10926","volume":"10","author":"G Hu","year":"2017","unstructured":"Hu\u00a0G, Chen\u00a0H, Liu\u00a0Q, Wei\u00a0J, Feng\u00a0Y, Fu\u00a0W, Zhang\u00a0M, Wu\u00a0H, Gu\u00a0B, Ren\u00a0J. Plexiform fibromyxoma of the stomach: a clinicopathological study of 10 cases. Int J Clin Exp Pathol. 2017;10(11):10926\u201333.","journal-title":"Int J Clin Exp Pathol"},{"issue":"1","key":"2740_CR3","doi-asserted-by":"publisher","DOI":"10.1002\/deo2.291","volume":"4","author":"N Sugimura","year":"2023","unstructured":"Sugimura\u00a0N, Kubota\u00a0E, Sasaki\u00a0M, Fukusada\u00a0S, Mizuno\u00a0Y, Iwasaki\u00a0H, Tanaka\u00a0M, Ozeki\u00a0K, Shimura\u00a0T, Kataoka\u00a0H. A case of asymptomatic gastric plexiform fibromyxoma followed up for 3 years. DEN Open. 2023;4(1)e291. https:\/\/doi.org\/10.1002\/deo2.291.","journal-title":"DEN Open"},{"issue":"31","key":"2740_CR4","doi-asserted-by":"publisher","first-page":"5817","DOI":"10.3748\/wjg.v23.i31.5817","volume":"23","author":"K Szurian","year":"2017","unstructured":"Szurian\u00a0K, Till\u00a0H, Amerstorfer\u00a0E, Hinteregger\u00a0N, Mischinger\u00a0HJ, Liegl-Atzwanger\u00a0B, Brcic\u00a0I. Rarity among benign gastric tumors: Plexiform fibromyxoma - Report of two cases. World J Gastroenterol. 2017;23(31):5817\u201322. https:\/\/doi.org\/10.3748\/wjg.v23.i31.5817.","journal-title":"World J Gastroenterol"},{"issue":"1","key":"2740_CR5","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2350\/13-09-1373-OA.1","volume":"17","author":"LV Duckworth","year":"2014","unstructured":"Duckworth\u00a0LV, Gonzalez\u00a0RS, Martelli\u00a0M, Liu\u00a0C, Coffin\u00a0CM, Reith\u00a0JD. Plexiform fibromyxoma: report of two pediatric cases and review of the literature. Pediatr Dev Pathol. 2014;17(1):21\u20137. https:\/\/doi.org\/10.2350\/13-09-1373-OA.1.","journal-title":"Pediatr Dev Pathol"},{"issue":"5","key":"2740_CR6","doi-asserted-by":"publisher","first-page":"648","DOI":"10.14309\/ajg.0000000000000491","volume":"115","author":"J Tang","year":"2020","unstructured":"Tang\u00a0J, Liu\u00a0F. Plexiform Fibromyxoma: A Rare Mesenchymal Tumor Found in the Esophagus. Am J Gastroenterol. 2020;115(5):648\u2013648. https:\/\/doi.org\/10.14309\/ajg.0000000000000491.","journal-title":"Am J Gastroenterol"},{"issue":"1","key":"2740_CR7","doi-asserted-by":"publisher","DOI":"10.1002\/deo2.291","volume":"4","author":"N Sugimura","year":"2023","unstructured":"Sugimura\u00a0N, Kubota\u00a0E, Sasaki\u00a0M, Fukusada\u00a0S, Mizuno\u00a0Y, Iwasaki\u00a0H, Tanaka\u00a0M, Ozeki\u00a0K, Shimura\u00a0T, Kataoka\u00a0H. A\u00a0case of asymptomatic gastric plexiform fibromyxoma followed up for 3\u00a0years. DEN Open. 2023;4(1)e291. https:\/\/doi.org\/10.1002\/deo2.291.","journal-title":"DEN Open"},{"issue":"3","key":"2740_CR8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0092001","volume":"9","author":"YW Wu","year":"2014","unstructured":"Wu\u00a0YW, Tseng\u00a0PH, Lee\u00a0YC, Wang\u00a0SY, Chiu\u00a0HM, Tu\u00a0CH, Wang\u00a0HP, Lin\u00a0JT, Wu\u00a0MS, Yang\u00a0WS. Association of esophageal inflammation, obesity and gastroesophageal reflux disease: from FDG PET\/CT perspective. PLoS One. 2014;9(3)e92001. https:\/\/doi.org\/10.1371\/journal.pone.0092001.","journal-title":"PLoS One"},{"issue":"36","key":"2740_CR9","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000027164","volume":"100","author":"M Lin","year":"2021","unstructured":"Lin\u00a0M, Song\u00a0L, Qin\u00a0S, Li\u00a0D, Hou\u00a0G, Li\u00a0X. Plexiform fibromyxoma: Case report and literature review. 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Int J Cancer. 2021;149(1):177\u201385. https:\/\/doi.org\/10.1002\/ijc.33536.","journal-title":"Int J Cancer"}],"container-title":["Wiener klinische Wochenschrift"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00508-026-02740-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00508-026-02740-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00508-026-02740-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T13:05:36Z","timestamp":1776776736000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00508-026-02740-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,21]]},"references-count":10,"alternative-id":["2740"],"URL":"https:\/\/doi.org\/10.1007\/s00508-026-02740-w","relation":{},"ISSN":["0043-5325","1613-7671"],"issn-type":[{"value":"0043-5325","type":"print"},{"value":"1613-7671","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,21]]},"assertion":[{"value":"16 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"P.\u00a0Swatek, E.\u00a0Ahmic, I.\u00a0Brcic, I.\u00a0Mykoliuk, A.\u00a0Busau, A.\u00a0Roj and J.\u00a0Lindenmann declare that they have no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Written informed consent was obtained from the patient for publication.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Patient consent"}}]}}