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Die CKD stellt eine bedeutende Herausforderung f\u00fcr das Gesundheitssystem dar, insbesondere aufgrund der geringen Erkrankungskenntnis der Betroffenen sowie der hohen Morbidit\u00e4t, Mortalit\u00e4t und Kosten.<\/jats:p>\n                  <jats:p>Im Fokus stehen zwei zentrale diagnostische Parameter \u2013\u00a0die gesch\u00e4tzte glomerul\u00e4re Filtrationsrate (eGFR) und die Albumin-Kreatinin-Ratio im Urin (uACR)\u00a0\u2013 als Grundlage f\u00fcr Fr\u00fcherkennung, Diagnosestellung und Verlaufs\u00fcberwachung. Das Papier identifiziert bestehende Defizite, insbesondere die unzureichende Nutzung der uACR im Screening sowie Probleme durch fehlende Standardisierung und methodische Heterogenit\u00e4t.<\/jats:p>\n                  <jats:p>Es werden konkrete Empfehlungen zur analytischen und pr\u00e4analytischen Standardisierung, zu einheitlichen Berechnungsmethoden insbesondere die Empfehlung zur Verwendung der EKFC-Formel zur Berechnung der eGFR, zur strukturierten Befunddarstellung sowie zur Integration von Risikobewertungen wie der Kidney Failure Risk Equation (KFRE) gegeben. Dar\u00fcber hinaus werden Ma\u00dfnahmen zur Qualit\u00e4tssicherung, einschlie\u00dflich externer Ringversuche, sowie die Bedeutung harmonisierter Befundformate f\u00fcr die klinische Interpretation hervorgehoben.<\/jats:p>\n                  <jats:p>Abschlie\u00dfend fordert das Konsensuspapier die systematische Integration der CKD-Fr\u00fcherkennung in die Prim\u00e4rversorgung, eine verbesserte Abrechenbarkeit diagnostischer Leistungen und eine st\u00e4rkere digitale Integration von Labordaten. Ziel ist es, die Fr\u00fcherkennung zu verbessern, die Vergleichbarkeit von Befunden sicherzustellen und die Versorgung von Patient:innen nachhaltig zu optimieren.<\/jats:p>","DOI":"10.1007\/s00508-026-02749-1","type":"journal-article","created":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T09:03:13Z","timestamp":1781254993000},"page":"611-622","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Konsensuspapier zur standardisierten Labordiagnostik der chronischen Nierenerkrankung (CKD) im Kontext kardiovaskul\u00e4r-renal-metabolischer Gesundheit (\u00d6GLMKC, \u00d6QUASTA, \u00d6GN)","Consensus paper for the standardized laboratory diagnostics of chronic kidney disease (CKD) in the context of cardiovascular-renal-metabolic health (\u00d6GLMKC, \u00d6QUASTA, \u00d6GN)"],"prefix":"10.1007","volume":"138","author":[{"given":"Kathrin","family":"Eller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Koller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Buchta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Exner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Greiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Griesmacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina","family":"Hellbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Karimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Mache","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"S\u00e4emann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Mustafa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,12]]},"reference":[{"key":"2749_CR1","doi-asserted-by":"publisher","first-page":"2461","DOI":"10.1016\/S0140-6736(25)01853-7","volume":"406","author":"GBD 2023 Chronic Kidney Disease Collaborators","year":"2025","unstructured":"GBD 2023 Chronic Kidney Disease Collaborators. 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