{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T10:34:18Z","timestamp":1761647658380},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2009,3,5]],"date-time":"2009-03-05T00:00:00Z","timestamp":1236211200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2009,11]]},"DOI":"10.1007\/s00520-009-0596-4","type":"journal-article","created":{"date-parts":[[2009,3,4]],"date-time":"2009-03-04T09:58:37Z","timestamp":1236160717000},"source":"Crossref","is-referenced-by-count":13,"title":["Longitudinal oncology registry of head and neck carcinoma (LORHAN\u00ae): initial supportive care findings"],"prefix":"10.1007","volume":"17","author":[{"given":"Barbara A.","family":"Murphy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Walter J.","family":"Curran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam S.","family":"Garden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul M.","family":"Harari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart J.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. Kian","family":"Ang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,3,5]]},"reference":[{"key":"596_CR1","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1200\/JCO.2003.01.008","volume":"21","author":"DJ Adelstein","year":"2003","unstructured":"Adelstein DJ, Adams G, Wagner H, Kish JA, Ensley JF, Schuller DE, Forastiere A (2003) An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer. J Clin Oncol 21:92\u201398 doi:\n                    10.1200\/JCO.2003.01.008","journal-title":"J Clin Oncol"},{"key":"596_CR2","first-page":"2a","volume":"20","author":"A Forastiere","year":"2001","unstructured":"Forastiere A, Berkey B, Maor M (2001) Phase III trial to preserve the larynx: induction chemotherapy and radiotherapy versus concomitant chemotherapy versus radiotherapy alone, intergroup trial R91\u201311. Proc Amer Soc Clin Oncol 20:2a, abstract # 4","journal-title":"Proc Amer Soc Clin Oncol"},{"key":"596_CR3","unstructured":"Bonner JA, Harari P, Giralt N, Azaria R, Cohen D, Raben C, Jones MS, Kies MS, Baselga J, Ang KK, Phase III study of high dose radiation with or without cetuximab in the treatment of locoregionally advanced squamous cell cancer of the head and neck. Proc Amer Soc Clin Oncol 204. 23: p. late breaking abstract"},{"key":"596_CR4","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1200\/JCO.1996.14.3.838","volume":"14","author":"S El-Sayed","year":"1996","unstructured":"El-Sayed S, Nelson N (1996) Adjuvant and adjunctive chemotherapy in the management of squamous cell carcinoma of the head and neck region. A meta-analysis of prospective and randomized trials. Clin Oncol 14:838\u2013847","journal-title":"Clin Oncol"},{"issue":"10","key":"596_CR5","first-page":"807","volume":"5","author":"BA Murphy","year":"2007","unstructured":"Murphy BA et al (2007) Symptom control issues and supportive care of patients with head and neck cancers. Clin Adv Hematol Oncol 5(10):807\u2013822","journal-title":"Clin Adv Hematol Oncol"},{"key":"596_CR6","doi-asserted-by":"crossref","unstructured":"Murphy BA, Chen A, Harari P, Curran W, Wong S, Bellm L, Gamber D, Dawson D, Garden A, Ang K (2007) Longitudinal oncology registry of head and neck carcinoma: (LORHAN), A new national cancer registry. Proceedings Multidisciplinary Head and Neck Cancer Symposium, p. Presentation #7.","DOI":"10.1016\/j.ijrobp.2007.06.008"},{"issue":"21","key":"596_CR7","doi-asserted-by":"publisher","first-page":"3582","DOI":"10.1200\/JCO.2007.14.8841","volume":"26","author":"M Machtay","year":"2008","unstructured":"Machtay M et al (2008) Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis. J Clin Oncol 26(21):3582\u20133589 doi:\n                    10.1200\/JCO.2007.14.8841","journal-title":"J Clin Oncol"},{"key":"596_CR8","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1097\/00005537-200004000-00011","volume":"110","author":"J Piccirillo","year":"2000","unstructured":"Piccirillo J (2000) Importance of comorbidity in head and neck cancer. Laryngoscope 110:593\u2013602 doi:\n                    10.1097\/00005537\u2013200004000\u201300011","journal-title":"Laryngoscope"},{"issue":"27","key":"596_CR9","doi-asserted-by":"publisher","first-page":"2061","DOI":"10.1056\/NEJM199912303412706","volume":"341","author":"LF Hutchins","year":"1999","unstructured":"Hutchins LF et al (1999) Underrepresentation of patients 65\u00a0years of age or older in cancer-treatment trials. N Engl J Med 341(27):2061\u20132067 doi:\n                    10.1056\/NEJM199912303412706","journal-title":"N Engl J Med"},{"issue":"12","key":"596_CR10","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1001\/archotol.125.12.1405","volume":"125","author":"WE Fee Jr","year":"1999","unstructured":"Fee WE Jr (1999) Surgery in the aging population. Arch Otolaryngol Head Neck Surg 125(12):1405, discussion 1406\u20137","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"7","key":"596_CR11","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1001\/archotol.131.7.605","volume":"131","author":"M Boruk","year":"2005","unstructured":"Boruk M et al (2005) Age as a prognostic factor for complications of major head and neck surgery. Arch Otolaryngol Head Neck Surg 131(7):605\u2013609 doi:\n                    10.1001\/archotol.131.7.605","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"3","key":"596_CR12","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1002\/(SICI)1097-0347(199805)20:3<216::AID-HED6>3.0.CO;2-3","volume":"20","author":"GL Clayman","year":"1998","unstructured":"Clayman GL et al (1998) Surgical outcomes in head and neck cancer patients 80 years of age and older. Head Neck 20(3):216\u2013223 doi:\n                    10.1002\/(SICI)1097-0347(199805)20:3<216::AID-HED6>3.0.CO;2-3","journal-title":"Head Neck"},{"key":"596_CR13","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1097\/01.PRS.0000152424.91250.A5","volume":"115","author":"O Koray Coskunfirat","year":"2005","unstructured":"Koray Coskunfirat O, Chen CH, Spanio S, Tang Y (2005) The safety of microvascular free tissue transfer in the elderly population. Plast Reconstr Surg 115:771\u2013775 doi:\n                    10.1097\/01.PRS.0000152424.91250.A5","journal-title":"Plast Reconstr Surg"},{"issue":"5","key":"596_CR14","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/S0748-7983(98)92186-2","volume":"24","author":"T Pignon","year":"1998","unstructured":"Pignon T, Scalliet P (1998) Radiotherapy in the elderly. Eur J Surg Oncol 24(5):407\u2013411 doi:\n                    10.1016\/S0748\u20137983(98)92186\u20132","journal-title":"Eur J Surg Oncol"},{"issue":"3","key":"596_CR15","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1002\/(SICI)1097-0142(20000201)88:3<648::AID-CNCR23>3.0.CO;2-R","volume":"88","author":"AS Allal","year":"2000","unstructured":"Allal AS et al (2000) Feasibility and early results of accelerated radiotherapy for head and neck carcinoma in the elderly. Cancer 88(3):648\u2013652 doi:\n                    10.1002\/(SICI)1097-0142(20000201)88:3<648::AID-CNCR23>3.0.CO;2-R","journal-title":"Cancer"},{"issue":"1","key":"596_CR16","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/S0167-8140(03)00249-4","volume":"69","author":"CP Schofield","year":"2003","unstructured":"Schofield CP et al (2003) Radiotherapy for head and neck cancer in elderly patients. Radiother Oncol 69(1):37\u201342 doi:\n                    10.1016\/S0167-8140(03)00249-4","journal-title":"Radiother Oncol"},{"issue":"9538","key":"596_CR17","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1016\/S0140-6736(06)69121-6","volume":"368","author":"J Bourhis","year":"2006","unstructured":"Bourhis J et al (2006) Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis. Lancet 368(9538):843\u2013854 doi:\n                    10.1016\/S0140-6736(06)69121-6","journal-title":"Lancet"},{"issue":"3","key":"596_CR18","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1097\/CCO.0b013e3280f01010","volume":"19","author":"J Bourhis","year":"2007","unstructured":"Bourhis J et al (2007) Individual patients\u2019 data meta-analyses in head and neck cancer. Curr Opin Oncol 19(3):188\u2013194 doi:\n                    10.1097\/CCO.0b013e3280f01010","journal-title":"Curr Opin Oncol"},{"issue":"10","key":"596_CR19","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1001\/archotol.128.10.1172","volume":"128","author":"JF Piccirillo","year":"2002","unstructured":"Piccirillo JF et al (2002) Development of a new head and neck cancer-specific comorbidity index. Arch Otolaryngol Head Neck Surg 128(10):1172\u20131179","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"1","key":"596_CR20","first-page":"61","volume":"15","author":"W Breitbart","year":"1988","unstructured":"Breitbart W, Holland J (1988) Psychosocial aspects of head and neck cancer. Semin Oncol 15(1):61\u201369","journal-title":"Semin Oncol"},{"key":"596_CR21","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/S0194-5998(99)70287-1","volume":"120","author":"MF DeBoer","year":"1999","unstructured":"DeBoer MF et al (1999) Physical and psychosocial correlates of head and neck cancer: a review of the literature. Otolaryngol Head Neck Surg 120:427\u2013436 doi:\n                    10.1016\/S0194-5998(99)70287-1","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"1","key":"596_CR22","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/oxfordjournals.annonc.a058365","volume":"4","author":"Y Rapoport","year":"1993","unstructured":"Rapoport Y, Kreitler S, Chaitchik S, Algor R, Weissler K (1993) Psychosocial problems in head-and-neck cancer patients and their change with time since diagnosis. Ann Oncol 4(1):69\u201373","journal-title":"Ann Oncol"},{"issue":"5","key":"596_CR23","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1002\/pon.656","volume":"12","author":"D Devine","year":"2003","unstructured":"Devine D, Parker P, Fouladi RT, Cohen L (2003) The association between social support, intrusive thoughts, avoidance, and adjustment following an experimental cancer treatment. Psychooncology 12(5):453\u2013462 doi:\n                    10.1002\/pon.656","journal-title":"Psychooncology"},{"issue":"5","key":"596_CR24","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1054\/bjom.2001.0652","volume":"39","author":"KA Hassanein","year":"2001","unstructured":"Hassanein KA, Musgrove B, Bradbury E (2001) Functional status of patients with oral cancer and its relation to style of coping, social support and psychological status. Br J Oral Maxillofac Surg 39(5):340\u2013345 doi:\n                    10.1054\/bjom.2001.0652","journal-title":"Br J Oral Maxillofac Surg"},{"issue":"26","key":"596_CR25","doi-asserted-by":"publisher","first-page":"4096","DOI":"10.1200\/JCO.2007.13.3983","volume":"25","author":"SM Bentzen","year":"2007","unstructured":"Bentzen SM, Trotti A (2007) Evaluation of early and late toxicities in chemoradiation trials. J Clin Oncol 25(26):4096\u20134103 doi:\n                    10.1200\/JCO.2007.13.3983","journal-title":"J Clin Oncol"},{"issue":"9 Suppl 4","key":"596_CR26","first-page":"13","volume":"5","author":"BA Murphy","year":"2007","unstructured":"Murphy BA (2007) Clinical and economic consequences of mucositis induced by chemotherapy and\/or radiation therapy. J Support Oncol 5(9 Suppl 4):13\u201321","journal-title":"J Support Oncol"},{"key":"596_CR27","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/S0167-8140(02)00404-8","volume":"66","author":"A Trotti","year":"2003","unstructured":"Trotti A, Bellm L, Epstein JB, Frame D, Fuchs HJ, Gwede CK, Komaroff E, Nalysnyk L, Zilbergerg MD (2003) Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: a systematic literature review. Radiother Oncol 66:253\u2013262 doi:\n                    10.1016\/S0167\u20138140(02)00404\u20138","journal-title":"Radiother Oncol"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-009-0596-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00520-009-0596-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-009-0596-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-009-0596-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,18]],"date-time":"2020-02-18T02:46:20Z","timestamp":1581993980000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00520-009-0596-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3,5]]},"references-count":27,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["596"],"URL":"https:\/\/doi.org\/10.1007\/s00520-009-0596-4","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,3,5]]},"article-number":"1393"}}