{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T17:42:28Z","timestamp":1792172548212,"version":"4.4.0"},"reference-count":63,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2013,2,23]],"date-time":"2013-02-23T00:00:00Z","timestamp":1361577600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1007\/s00520-013-1732-8","type":"journal-article","created":{"date-parts":[[2013,2,22]],"date-time":"2013-02-22T02:41:29Z","timestamp":1361500889000},"page":"1461-1474","source":"Crossref","is-referenced-by-count":42,"title":["Pharmacological and non-hormonal treatment of hot flashes in breast cancer survivors: CEPO review and recommendations"],"prefix":"10.1007","volume":"21","author":[{"name":"Comit\u00e9 de l\u2019\u00e9volution des pratiques en oncologie (CEPO)","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvain","family":"L\u2019Esp\u00e9rance","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne","family":"Frenette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Dionne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Yves","family":"Dionne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,2,23]]},"reference":[{"key":"1732_CR1","unstructured":"Comit\u00e9 Directeur de la Soci\u00e9t\u00e9 Canadienne du Cancer. Statistiques Canadiennes sur le Cancer 2012. Soci\u00e9t\u00e9 Canadienne du Cancer, Toronto"},{"issue":"6","key":"1732_CR2","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1634\/theoncologist.11-6-641","volume":"11","author":"AH Boekhout","year":"2006","unstructured":"Boekhout AH, Beijnen JH, Schellens JH (2006) Symptoms and treatment in cancer therapy-induced early menopause. Oncologist 11(6):641\u2013654. doi: 10.1634\/theoncologist.11-6-641","journal-title":"Oncologist"},{"issue":"4","key":"1732_CR3","first-page":"339","volume":"91","author":"P Debourdeau","year":"2004","unstructured":"Debourdeau P, Bachelot T, Zammit C, Aletti M, Gallineau C, Gligorov J (2004) Treatment of hot flashes in women with a previous diagnosis of breast cancer. Bull Cancer 91(4):339\u2013349","journal-title":"Bull Cancer"},{"issue":"7","key":"1732_CR4","first-page":"315","volume":"4","author":"S Dalal","year":"2006","unstructured":"Dalal S, Zhukovsky DS (2006) Pathophysiology and management of hot flashes. J Support Oncol 4(7):315\u2013320, 325","journal-title":"J Support Oncol"},{"issue":"6","key":"1732_CR5","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/S0885-3924(01)00353-0","volume":"22","author":"JS Carpenter","year":"2001","unstructured":"Carpenter JS (2001) The hot flash related daily interference scale: a tool for assessing the impact of hot flashes on quality of life following breast cancer. J Pain Symptom Manag 22(6):979\u2013989","journal-title":"J Pain Symptom Manag"},{"issue":"3","key":"1732_CR6","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0378-5122(96)82006-8","volume":"24","author":"JR Hilditch","year":"1996","unstructured":"Hilditch JR, Lewis J, Peter A, van Maris B, Ross A, Franssen E, Guyatt GH, Norton PG, Dunn E (1996) A menopause-specific quality of life questionnaire: development and psychometric properties. Maturitas 24(3):161\u2013175","journal-title":"Maturitas"},{"issue":"1","key":"1732_CR7","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/BF00435972","volume":"5","author":"K Thirlaway","year":"1996","unstructured":"Thirlaway K, Fallowfield L, Cuzick J (1996) The sexual activity questionnaire: a measure of women\u2019s sexual functioning. Qual Life Res 5(1):81\u201390","journal-title":"Qual Life Res"},{"issue":"3","key":"1732_CR8","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0378-5122(92)90116-L","volume":"14","author":"I Wiklund","year":"1992","unstructured":"Wiklund I, Holst J, Karlberg J, Mattsson LA, Samsioe G, Sandin K, Uvebrant M, von Schoultz B (1992) A new methodological approach to the evaluation of quality of life in postmenopausal women. Maturitas 14(3):211\u2013224","journal-title":"Maturitas"},{"issue":"3","key":"1732_CR9","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1001\/jama.288.3.321","volume":"288","author":"JE Rossouw","year":"2002","unstructured":"Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, Jackson RD, Beresford SA, Howard BV, Johnson KC, Kotchen JM, Ockene J (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women\u2019s Health Initiative randomized controlled trial. JAMA 288(3):321\u2013333","journal-title":"JAMA"},{"issue":"9382","key":"1732_CR10","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0140-6736(03)14065-2","volume":"362","author":"V Beral","year":"2003","unstructured":"Beral V (2003) Breast cancer and hormone-replacement therapy in the Million Women Study. Lancet 362(9382):419\u2013427","journal-title":"Lancet"},{"issue":"8","key":"1732_CR11","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1200\/JCO.2001.19.8.2357","volume":"19","author":"NF Col","year":"2001","unstructured":"Col NF, Hirota LK, Orr RK, Erban JK, Wong JB, Lau J (2001) Hormone replacement therapy after breast cancer: a systematic review and quantitative assessment of risk. J Clin Oncol 19(8):2357\u20132363","journal-title":"J Clin Oncol"},{"issue":"7","key":"1732_CR12","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1093\/jnci\/dji071","volume":"97","author":"E Schoultz von","year":"2005","unstructured":"von Schoultz E, Rutqvist LE (2005) Menopausal hormone therapy after breast cancer: the Stockholm randomized trial. J Natl Cancer Inst 97(7):533\u2013535. doi: 10.1093\/jnci\/dji071","journal-title":"J Natl Cancer Inst"},{"issue":"9407","key":"1732_CR13","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0140-6736(04)15493-7","volume":"363","author":"L Holmberg","year":"2004","unstructured":"Holmberg L, Anderson H (2004) HABITS (hormonal replacement therapy after breast cancer\u2014is it safe?), a randomised comparison: trial stopped. Lancet 363(9407):453\u2013455. doi: 10.1016\/S0140-6736(04)15493-7","journal-title":"Lancet"},{"issue":"7","key":"1732_CR14","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1093\/jnci\/djn058","volume":"100","author":"L Holmberg","year":"2008","unstructured":"Holmberg L, Iversen OE, Rudenstam CM, Hammar M, Kumpulainen E, Jaskiewicz J, Jassem J, Dobaczewska D, Fjosne HE, Peralta O, Arriagada R, Holmqvist M, Maenpaa J (2008) Increased risk of recurrence after hormone replacement therapy in breast cancer survivors. J Natl Cancer Inst 100(7):475\u2013482. doi: 10.1093\/jnci\/djn058","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"1732_CR15","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1634\/theoncologist.12-1-124","volume":"12","author":"JS Carpenter","year":"2007","unstructured":"Carpenter JS, Storniolo AM, Johns S, Monahan PO, Azzouz F, Elam JL, Johnson CS, Shelton RC (2007) Randomized, double-blind, placebo-controlled crossover trials of venlafaxine for hot flashes after breast cancer. Oncologist 12(1):124\u2013135. doi: 10.1634\/theoncologist.12-1-124","journal-title":"Oncologist"},{"issue":"9247","key":"1732_CR16","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1016\/S0140-6736(00)03403-6","volume":"356","author":"CL Loprinzi","year":"2000","unstructured":"Loprinzi CL, Kugler JW, Sloan JA, Mailliard JA, LaVasseur BI, Barton DL, Novotny PJ, Dakhil SR, Rodger K, Rummans TA, Christensen BJ (2000) Venlafaxine in management of hot flashes in survivors of breast cancer: a randomised controlled trial. Lancet 356(9247):2059\u20132063. doi: 10.1016\/S0140-6736(00)03403-6","journal-title":"Lancet"},{"key":"1732_CR17","doi-asserted-by":"crossref","unstructured":"Boekhout AH, Vincent AD, Dalesio OB, van den Bosch J, Foekema-Tons JH, Adriaansz S, Sprangers S, Nuijen B, Beijnen JH, Schellens JH (2011) Management of hot flashes in patients who have breast cancer with venlafaxine and clonidine: a randomized, double-blind, placebo-controlled trial. J Clin Oncol. doi: 10.1200\/JCO.2010.33.1298","DOI":"10.1200\/JCO.2010.33.1298"},{"issue":"3","key":"1732_CR18","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/s10549-008-0138-7","volume":"115","author":"C Buijs","year":"2009","unstructured":"Buijs C, Mom CH, Willemse PH, Marike Boezen H, Maurer JM, Wymenga AN, de Jong RS, Nieboer P, de Vries EG, Mourits MJ (2009) Venlafaxine versus clonidine for the treatment of hot flashes in breast cancer patients: a double-blind, randomized cross-over study. Breast Cancer Res Treat 115(3):573\u2013580. doi: 10.1007\/s10549-008-0138-7","journal-title":"Breast Cancer Res Treat"},{"issue":"4","key":"1732_CR19","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1093\/annonc\/mdl478","volume":"18","author":"S Loibl","year":"2007","unstructured":"Loibl S, Schwedler K, von Minckwitz G, Strohmeier R, Mehta KM, Kaufmann M (2007) Venlafaxine is superior to clonidine as treatment of hot flashes in breast cancer patients\u2014a double-blind, randomized study. Ann Oncol 18(4):689\u2013693. doi: 10.1093\/annonc\/mdl478","journal-title":"Ann Oncol"},{"issue":"28","key":"1732_CR20","doi-asserted-by":"crossref","first-page":"6919","DOI":"10.1200\/JCO.2005.10.081","volume":"23","author":"V Stearns","year":"2005","unstructured":"Stearns V, Slack R, Greep N, Henry-Tilman R, Osborne M, Bunnell C, Ullmer L, Gallagher A, Cullen J, Gehan E, Hayes DF, Isaacs C (2005) Paroxetine is an effective treatment for hot flashes: results from a prospective randomized clinical trial. J Clin Oncol 23(28):6919\u20136930. doi: 10.1200\/JCO.2005.10.081","journal-title":"J Clin Oncol"},{"issue":"6","key":"1732_CR21","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1200\/JCO.20.6.1578","volume":"20","author":"CL Loprinzi","year":"2002","unstructured":"Loprinzi CL, Sloan JA, Perez EA, Quella SK, Stella PJ, Mailliard JA, Halyard MY, Pruthi S, Novotny PJ, Rummans TA (2002) Phase III evaluation of fluoxetine for treatment of hot flashes. J Clin Oncol 20(6):1578\u20131583","journal-title":"J Clin Oncol"},{"issue":"2","key":"1732_CR22","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s10549-009-0425-y","volume":"118","author":"MF Wu","year":"2009","unstructured":"Wu MF, Hilsenbeck SG, Tham YL, Kramer R, Elledge RM, Chang JC, Friedman LC (2009) The efficacy of sertraline for controlling hot flashes in women with or at high risk of developing breast cancer. Breast Cancer Res Treat 118(2):369\u2013375. doi: 10.1007\/s10549-009-0425-y","journal-title":"Breast Cancer Res Treat"},{"issue":"2","key":"1732_CR23","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.1075-122X.2006.00218.x","volume":"12","author":"GG Kimmick","year":"2006","unstructured":"Kimmick GG, Lovato J, McQuellon R, Robinson E, Muss HB (2006) Randomized, double-blind, placebo-controlled, crossover study of sertraline (Zoloft) for the treatment of hot flashes in women with early stage breast cancer taking tamoxifen. Breast J 12(2):114\u2013122. doi: 10.1111\/j.1075-122X.2006.00218.x","journal-title":"Breast J"},{"issue":"20","key":"1732_CR24","doi-asserted-by":"crossref","first-page":"3278","DOI":"10.1200\/JCO.2009.26.6379","volume":"28","author":"DL Barton","year":"2010","unstructured":"Barton DL, LaVasseur BI, Sloan JA, Stawis AN, Flynn KA, Dyar M, Johnson DB, Atherton PJ, Diekmann B, Loprinzi CL (2010) Phase III, placebo-controlled trial of three doses of citalopram for the treatment of hot flashes: NCCTG trial N05C9. J Clin Oncol 28(20):3278\u20133283. doi: 10.1200\/JCO.2009.26.6379","journal-title":"J Clin Oncol"},{"issue":"2","key":"1732_CR25","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/01.gme.0000243571.55699.4a","volume":"14","author":"AE Kalay","year":"2007","unstructured":"Kalay AE, Demir B, Haberal A, Kalay M, Kandemir O (2007) Efficacy of citalopram on climacteric symptoms. Menopause 14(2):223\u2013229. doi: 10.1097\/01.gme.0000243571.55699.4a","journal-title":"Menopause"},{"issue":"10","key":"1732_CR26","doi-asserted-by":"crossref","first-page":"788","DOI":"10.7326\/0003-4819-132-10-200005160-00004","volume":"132","author":"KJ Pandya","year":"2000","unstructured":"Pandya KJ, Raubertas RF, Flynn PJ, Hynes HE, Rosenbluth RJ, Kirshner JJ, Pierce HI, Dragalin V, Morrow GR (2000) Oral clonidine in postmenopausal patients with breast cancer experiencing tamoxifen-induced hot flashes: a University of Rochester Cancer Center Community Clinical Oncology Program study. Ann Intern Med 132(10):788\u2013793","journal-title":"Ann Intern Med"},{"issue":"35","key":"1732_CR27","doi-asserted-by":"crossref","first-page":"5147","DOI":"10.1200\/JCO.2010.29.9230","volume":"28","author":"L Bordeleau","year":"2010","unstructured":"Bordeleau L, Pritchard KI, Loprinzi CL, Ennis M, Jugovic O, Warr D, Haq R, Goodwin PJ (2010) Multicenter, randomized, cross-over clinical trial of venlafaxine versus gabapentin for the management of hot flashes in breast cancer survivors. J Clin Oncol 28(35):5147\u20135152. doi: 10.1200\/JCO.2010.29.9230","journal-title":"J Clin Oncol"},{"issue":"4","key":"1732_CR28","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1080\/13697130902736921","volume":"12","author":"N Biglia","year":"2009","unstructured":"Biglia N, Sgandurra P, Peano E, Marenco D, Moggio G, Bounous V, Tomasi Cont N, Ponzone R, Sismondi P (2009) Non-hormonal treatment of hot flushes in breast cancer survivors: gabapentin vs. vitamin E. Climacteric 12(4):310\u2013318. doi: 10.1080\/13697130902736921","journal-title":"Climacteric"},{"issue":"3","key":"1732_CR29","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1200\/JCO.2006.07.5390","volume":"25","author":"CL Loprinzi","year":"2007","unstructured":"Loprinzi CL, Kugler JW, Barton DL, Dueck AC, Tschetter LK, Nelimark RA, Balcueva EP, Burger KN, Novotny PJ, Carlson MD, Duane SF, Corso SW, Johnson DB, Jaslowski AJ (2007) Phase III trial of gabapentin alone or in conjunction with an antidepressant in the management of hot flashes in women who have inadequate control with an antidepressant alone: NCCTG N03C5. J Clin Oncol 25(3):308\u2013312. doi: 10.1200\/JCO.2006.07.5390","journal-title":"J Clin Oncol"},{"issue":"9488","key":"1732_CR30","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/S0140-6736(05)67215-7","volume":"366","author":"KJ Pandya","year":"2005","unstructured":"Pandya KJ, Morrow GR, Roscoe JA, Zhao H, Hickok JT, Pajon E, Sweeney TJ, Banerjee TK, Flynn PJ (2005) Gabapentin for hot flashes in 420 women with breast cancer: a randomised double-blind placebo-controlled trial. Lancet 366(9488):818\u2013824. doi: 10.1016\/S0140-6736(05)67215-7","journal-title":"Lancet"},{"issue":"4","key":"1732_CR31","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1200\/JCO.2009.24.5647","volume":"28","author":"CL Loprinzi","year":"2010","unstructured":"Loprinzi CL, Qin R, Balcueva EP, Flynn KA, Rowland KM Jr, Graham DL, Erwin NK, Dakhil SR, Jurgens DJ, Burger KN (2010) Phase III, randomized, double-blind, placebo-controlled evaluation of pregabalin for alleviating hot flashes, N07C1. J Clin Oncol 28(4):641\u2013647. doi: 10.1200\/JCO.2009.24.5647","journal-title":"J Clin Oncol"},{"key":"1732_CR32","doi-asserted-by":"crossref","unstructured":"Pruthi S, Qin R, Terstreip SA, Liu H, Loprinzi CL, Shah TR, Tucker KF, Dakhil SR, Bury MJ, Carolla RL, Steen PD, Vuky J, Barton DL (2012) A phase III, randomized, placebo-controlled, double-blind trial of flaxseed for the treatment of hot flashes: North Central Cancer Treatment Group N08C7. Menopause 19(1):48\u201353","DOI":"10.1097\/gme.0b013e318223b021"},{"issue":"5","key":"1732_CR33","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.ejca.2005.01.005","volume":"41","author":"CA MacGregor","year":"2005","unstructured":"MacGregor CA, Canney PA, Patterson G, McDonald R, Paul J (2005) A randomised double-blind controlled trial of oral soy supplements versus placebo for treatment of menopausal symptoms in patients with early breast cancer. Eur J Cancer 41(5):708\u2013714. doi: 10.1016\/j.ejca.2005.01.005","journal-title":"Eur J Cancer"},{"issue":"6","key":"1732_CR34","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1016\/S0029-7844(03)00232-1","volume":"101","author":"E Nikander","year":"2003","unstructured":"Nikander E, Kilkkinen A, Metsa-Heikkila M, Adlercreutz H, Pietinen P, Tiitinen A, Ylikorkala O (2003) A randomized placebo-controlled crossover trial with phytoestrogens in treatment of menopause in breast cancer patients. Obstet Gynecol 101(6):1213\u20131220","journal-title":"Obstet Gynecol"},{"issue":"6","key":"1732_CR35","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1200\/JCO.20.6.1449","volume":"20","author":"CL Patten Van","year":"2002","unstructured":"Van Patten CL, Olivotto IA, Chambers GK, Gelmon KA, Hislop TG, Templeton E, Wattie A, Prior JC (2002) Effect of soy phytoestrogens on hot flashes in postmenopausal women with breast cancer: a randomized, controlled clinical trial. J Clin Oncol 20(6):1449\u20131455","journal-title":"J Clin Oncol"},{"issue":"5","key":"1732_CR36","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1200\/JCO.2000.18.5.1068","volume":"18","author":"SK Quella","year":"2000","unstructured":"Quella SK, Loprinzi CL, Barton DL, Knost JA, Sloan JA, LaVasseur BI, Swan D, Krupp KR, Miller KD, Novotny PJ (2000) Evaluation of soy phytoestrogens for the treatment of hot flashes in breast cancer survivors: a North Central Cancer Treatment Group Trial. J Clin Oncol 18(5):1068\u20131074","journal-title":"J Clin Oncol"},{"issue":"18","key":"1732_CR37","doi-asserted-by":"crossref","first-page":"2836","DOI":"10.1200\/JCO.2005.05.4296","volume":"24","author":"BA Pockaj","year":"2006","unstructured":"Pockaj BA, Gallagher JG, Loprinzi CL, Stella PJ, Barton DL, Sloan JA, Lavasseur BI, Rao RM, Fitch TR, Rowland KM, Novotny PJ, Flynn PJ, Richelson E, Fauq AH (2006) Phase III double-blind, randomized, placebo-controlled crossover trial of black cohosh in the management of hot flashes: NCCTG Trial N01CC1. J Clin Oncol 24(18):2836\u20132841. doi: 10.1200\/JCO.2005.05.4296","journal-title":"J Clin Oncol"},{"issue":"10","key":"1732_CR38","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1200\/JCO.2001.19.10.2739","volume":"19","author":"JS Jacobson","year":"2001","unstructured":"Jacobson JS, Troxel AB, Evans J, Klaus L, Vahdat L, Kinne D, Lo KM, Moore A, Rosenman PJ, Kaufman EL, Neugut AI, Grann VR (2001) Randomized trial of black cohosh for the treatment of hot flashes among women with a history of breast cancer. J Clin Oncol 19(10):2739\u20132745","journal-title":"J Clin Oncol"},{"issue":"Suppl 1","key":"1732_CR39","doi-asserted-by":"crossref","first-page":"S59","DOI":"10.1016\/S0378-5122(02)00349-3","volume":"44","author":"G Hernandez Munoz","year":"2003","unstructured":"Hernandez Munoz G, Pluchino S (2003) Cimicifuga racemosa for the treatment of hot flushes in women surviving breast cancer. Maturitas 44(Suppl 1):S59\u2013S65","journal-title":"Maturitas"},{"issue":"2","key":"1732_CR40","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1097\/gme.0b013e31818572a0","volume":"16","author":"M Al-Akoum","year":"2009","unstructured":"Al-Akoum M, Maunsell E, Verreault R, Provencher L, Otis H, Dodin S (2009) Effects of Hypericum perforatum (St. John\u2019s wort) on hot flashes and quality of life in perimenopausal women: a randomized pilot trial. Menopause 16(2):307\u2013314. doi: 10.1097\/gme.0b013e31818572a0","journal-title":"Menopause"},{"issue":"2","key":"1732_CR41","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.maturitas.2010.11.013","volume":"68","author":"S Loibl","year":"2011","unstructured":"Loibl S, Lintermans A, Dieudonne AS, Neven P (2011) Management of menopausal symptoms in breast cancer patients. Maturitas 68(2):148\u2013154. doi: 10.1016\/j.maturitas.2010.11.013","journal-title":"Maturitas"},{"issue":"4","key":"1732_CR42","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.gyobfe.2012.02.015","volume":"40","author":"G Boutet","year":"2012","unstructured":"Boutet G (2012) Management of hot flushes for breast cancer survivors. Gynecol Obstet Fertil 40(4):241\u2013254. doi: 10.1016\/j.gyobfe.2012.02.015","journal-title":"Gynecol Obstet Fertil"},{"issue":"6","key":"1732_CR43","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0305-7372(02)00089-0","volume":"28","author":"M Clemons","year":"2002","unstructured":"Clemons M, Clamp A, Anderson B (2002) Management of the menopause in cancer survivors. Cancer Treat Rev 28(6):321\u2013333","journal-title":"Cancer Treat Rev"},{"issue":"12","key":"1732_CR44","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.4088\/JCP.08r04856blu","volume":"70","author":"JE Desmarais","year":"2009","unstructured":"Desmarais JE, Looper KJ (2009) Interactions between tamoxifen and antidepressants via cytochrome P450 2D6. J Clin Psychiatry 70(12):1688\u20131697. doi: 10.4088\/JCP.08r04856blu","journal-title":"J Clin Psychiatry"},{"key":"1732_CR45","unstructured":"Pal (2010) CYP2D6 testing falls short as predictor of adjuvant tamoxifen efficacy http:\/\/www.cancernetwork.com\/conference-reports\/sabcs2010\/content\/article\/10165\/1756542 . Accessed 30 janvier 2012"},{"key":"1732_CR46","unstructured":"National Institute for Clinical Excellence (2009) Early and locally advanced breast cancer: diagnosis and treatment. National Collaborating Centre for Cancer"},{"key":"1732_CR47","unstructured":"National Comprehensive Cancer Network (2011) NCCN Guidelines Version 2.2011 Breast cancer"},{"issue":"10","key":"1732_CR48","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1093\/annonc\/mdn353","volume":"19","author":"M Hickey","year":"2008","unstructured":"Hickey M, Saunders C, Partridge A, Santoro N, Joffe H, Stearns V (2008) Practical clinical guidelines for assessing and managing menopausal symptoms after breast cancer. Ann Oncol 19(10):1669\u20131680. doi: 10.1093\/annonc\/mdn353","journal-title":"Ann Oncol"},{"key":"1732_CR49","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/S1701-2163(16)34079-8","volume":"222","author":"RL Reid","year":"2009","unstructured":"Reid RL, Blake J, Abramson B, Khan A, Senikas V, Fortier M (2009) Menopause and osteoporosis update 2009. J Obstet Gynaecol Can 222:S1\u2013S47","journal-title":"J Obstet Gynaecol Can"},{"key":"1732_CR50","unstructured":"American Association of Clinical Endocrinologists (2006) Medical guidelines for clinical practice for the diagnostic and treatment of menopause"},{"issue":"1","key":"1732_CR51","doi-asserted-by":"crossref","first-page":"38","DOI":"10.3816\/SCT.2006.n.030","volume":"4","author":"YC Chang","year":"2006","unstructured":"Chang YC, Parker J, Dooley WC (2006) Hot flash therapies in breast cancer survivors. Support Cancer Ther 4(1):38\u201348. doi: 10.3816\/SCT.2006.n.030","journal-title":"Support Cancer Ther"},{"issue":"10","key":"1732_CR52","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.amjmed.2009.04.018","volume":"122","author":"CB Tempfer","year":"2009","unstructured":"Tempfer CB, Froese G, Heinze G, Bentz EK, Hefler LA, Huber JC (2009) Side effects of phytoestrogens: a meta-analysis of randomized trials. Am J Med 122(10):939\u2013946. doi: 10.1016\/j.amjmed.2009.04.018 , e939","journal-title":"Am J Med"},{"issue":"13","key":"1732_CR53","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1016\/j.ejca.2008.05.019","volume":"44","author":"LS Velentzis","year":"2008","unstructured":"Velentzis LS, Woodside JV, Cantwell MM, Leathem AJ, Keshtgar MR (2008) Do phytoestrogens reduce the risk of breast cancer and breast cancer recurrence? What clinicians need to know. Eur J Cancer 44(13):1799\u20131806. doi: 10.1016\/j.ejca.2008.05.019","journal-title":"Eur J Cancer"},{"issue":"3","key":"1732_CR54","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1186\/bcr781","volume":"6","author":"JL Limer","year":"2004","unstructured":"Limer JL, Speirs V (2004) Phyto-oestrogens and breast cancer chemoprevention. Breast Cancer Res 6(3):119\u2013127. doi: 10.1186\/bcr781bcr781","journal-title":"Breast Cancer Res"},{"issue":"7","key":"1732_CR55","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1089\/154099903322404276","volume":"12","author":"C Duffy","year":"2003","unstructured":"Duffy C, Cyr M (2003) Phytoestrogens: potential benefits and implications for breast cancer survivors. J Womens Health (Larchmt) 12(7):617\u2013631. doi: 10.1089\/154099903322404276","journal-title":"J Womens Health (Larchmt)"},{"key":"1732_CR56","doi-asserted-by":"crossref","unstructured":"Li J, Godecke T, Chen SN, Imai A, Lankin DC, Farnsworth NR, Pauli GF, van Breemen RB, Nikolic D (2011) In vitro metabolic interactions between black cohosh (Cimicifuga racemosa) and tamoxifen via inhibition of cytochromes P450 2D6 and 3A4. Xenobiotica. doi: 10.3109\/00498254.2011.603385","DOI":"10.3109\/00498254.2011.603385"},{"issue":"10","key":"1732_CR57","doi-asserted-by":"crossref","first-page":"844","DOI":"10.3109\/09513590.2010.538097","volume":"27","author":"M Rostock","year":"2011","unstructured":"Rostock M, Fischer J, Mumm A, Stammwitz U, Saller R, Bartsch HH (2011) Black cohosh (Cimicifuga racemosa) in tamoxifen-treated breast cancer patients with climacteric complaints\u2014a prospective observational study. Gynecol Endocrinol 27(10):844\u2013848. doi: 10.3109\/09513590.2010.538097","journal-title":"Gynecol Endocrinol"},{"issue":"11","key":"1732_CR58","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1139\/Y07-111","volume":"85","author":"M Al-Akoum","year":"2007","unstructured":"Al-Akoum M, Dodin S, Akoum A (2007) Synergistic cytotoxic effects of tamoxifen and black cohosh on MCF-7 and MDA-MB-231 human breast cancer cells: an in vitro study. Can J Physiol Pharmacol 85(11):1153\u20131159. doi: 10.1139\/Y07-111","journal-title":"Can J Physiol Pharmacol"},{"issue":"1","key":"1732_CR59","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1023\/A:1020241509382","volume":"76","author":"C Bodinet","year":"2002","unstructured":"Bodinet C, Freudenstein J (2002) Influence of Cimicifuga racemosa on the proliferation of estrogen receptor-positive human breast cancer cells. Breast Cancer Res Treat 76(1):1\u201310","journal-title":"Breast Cancer Res Treat"},{"issue":"1","key":"1732_CR60","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.phrs.2008.05.008","volume":"58","author":"F Borrelli","year":"2008","unstructured":"Borrelli F, Ernst E (2008) Black cohosh (Cimicifuga racemosa) for menopausal symptoms: a systematic review of its efficacy. Pharmacol Res 58(1):8\u201314. doi: 10.1016\/j.phrs.2008.05.008","journal-title":"Pharmacol Res"},{"issue":"6","key":"1732_CR61","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1517\/14740338.3.6.615","volume":"3","author":"A Huntley","year":"2004","unstructured":"Huntley A (2004) The safety of black cohosh (Actaea racemosa, Cimicifuga racemosa). Expert Opin Drug Saf 3(6):615\u2013623","journal-title":"Expert Opin Drug Saf"},{"key":"1732_CR62","unstructured":"Coll\u00e8ge des m\u00e9decins du Qu\u00e9bec et Ordre des pharmaciens du Qu\u00e9bec (2004) Les produits de sant\u00e9 naturels: Pour mieux conseiller vos patients. document de r\u00e9f\u00e9rence 1\u201325"},{"issue":"4 Suppl","key":"1732_CR63","first-page":"305S","volume":"102","author":"DJ Cook","year":"1992","unstructured":"Cook DJ, Guyatt GH, Laupacis A, Sackett DL (1992) Rules of evidence and clinical recommendations on the use of antithrombotic agents. Chest 102(4 Suppl):305S\u2013311S","journal-title":"Chest"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-013-1732-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00520-013-1732-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-013-1732-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T22:04:24Z","timestamp":1559081064000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00520-013-1732-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,23]]},"references-count":63,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["1732"],"URL":"https:\/\/doi.org\/10.1007\/s00520-013-1732-8","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,23]]}}}