{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:01:19Z","timestamp":1790006479720,"version":"4.0.1"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2015,2,15]],"date-time":"2015-02-15T00:00:00Z","timestamp":1423958400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1007\/s00520-015-2642-8","type":"journal-article","created":{"date-parts":[[2015,2,17]],"date-time":"2015-02-17T05:44:40Z","timestamp":1424151880000},"page":"2769-2777","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":85,"title":["Cancer treatment-related neuropathic pain: proof of concept study with menthol\u2014a TRPM8 agonist"],"prefix":"10.1007","volume":"23","author":[{"given":"M. T.","family":"Fallon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. J.","family":"Storey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Krishan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. J.","family":"Weir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. M.","family":"Fleetwood-Walker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. C.","family":"Scott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. A.","family":"Colvin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,2,15]]},"reference":[{"issue":"15","key":"2642_CR1","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1212\/01.wnl.0000259085.61898.9e","volume":"68","author":"MP Jensen","year":"2007","unstructured":"Jensen MP, Chodroff MJ, Dworkin RH (2007) The impact of neuropathic pain on health-related quality of life: review and implications. Neurology 68(15):1178\u20131182","journal-title":"Neurology"},{"key":"2642_CR2","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.jpain.2005.11.008","volume":"7","author":"N Torrance","year":"2006","unstructured":"Torrance N, Smith BH, Bennett MI et al (2006) The epidemiology of chronic pain of predominantly neuropathic origin. Results from a general population survey. J Pain 7:281\u2013289","journal-title":"J Pain"},{"issue":"2","key":"2642_CR3","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.pain.2010.02.034","volume":"149","author":"AH Doth","year":"2010","unstructured":"Doth AH, Hansson PT, Jensen MP et al (2010) The burden of neuropathic pain: a systematic review and meta-analysis of health utilities. Pain 149(2):338\u2013344","journal-title":"Pain"},{"issue":"5","key":"2642_CR4","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1111\/j.1526-4637.2009.00655.x","volume":"10","author":"C Toth","year":"2009","unstructured":"Toth C, Lander J, Wiebe S (2009) The prevalence and impact of chronic pain with neuropathic pain symptoms in the general population. Pain Med 10(5):918\u2013929","journal-title":"Pain Med"},{"key":"2642_CR5","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s11940-010-0108-3","volume":"13","author":"G Cavaletti","year":"2011","unstructured":"Cavaletti G, Alberti P, Frigeni B et al (2011) Chemotherapy-induced neuropathy. Curr Treat Options Neurol 13:180\u2013190","journal-title":"Curr Treat Options Neurol"},{"issue":"2","key":"2642_CR6","first-page":"1","volume":"20","author":"D Naleschinski","year":"2012","unstructured":"Naleschinski D, Baron R, Miaskowski C (2012) Identification and treatment of neuropathic pain in patients with cancer. Pain Clin Updat 20(2):1\u20135","journal-title":"Pain Clin Updat"},{"key":"2642_CR7","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1093\/annonc\/mdp594","volume":"21","author":"D Storey","year":"2010","unstructured":"Storey D, Sakala M, McLean C et al (2010) Capecitabine combined with oxaliplatin (CapOx) in clinical practice: how significant is peripheral neuropathy? Ann Oncol 21:1657\u20131661","journal-title":"Ann Oncol"},{"key":"2642_CR8","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.ctrv.2008.01.003","volume":"34","author":"AA Argyriou","year":"2008","unstructured":"Argyriou AA, Polychronopoulos P, Iconomou G et al (2008) A review on oxaliplatin-induced peripheral nerve damage. Cancer Treat Rev 34:368\u2013377","journal-title":"Cancer Treat Rev"},{"key":"2642_CR9","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1093\/jnci\/djh323","volume":"96","author":"PA Vasey","year":"2004","unstructured":"Vasey PA, Jayson GC, Gordon A et al (2004) Phase III randomized trial of docetaxel-carboplatin versus paclitaxel-carboplatin as first-line chemotherapy for ovarian carcinoma. J Natl Cancer Inst 96:1682\u20131691","journal-title":"J Natl Cancer Inst"},{"key":"2642_CR10","doi-asserted-by":"crossref","first-page":"3113","DOI":"10.1200\/JCO.2005.04.7779","volume":"24","author":"PG Richardson","year":"2006","unstructured":"Richardson PG, Briemberg H, Jagannath S et al (2006) Frequency, characteristics, and reversibility of peripheral neuropathy during treatment of advanced multiple myeloma with bortezomib. J Clin Oncol 24:3113\u20133120","journal-title":"J Clin Oncol"},{"key":"2642_CR11","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1016\/S0140-6736(06)68700-X","volume":"367","author":"H Kehlet","year":"2006","unstructured":"Kehlet H, Jensen TS, Woolf CJ (2006) Persistent postsurgical pain: risk factors and prevention. Lancet 367:1618\u20131625","journal-title":"Lancet"},{"issue":"18","key":"2642_CR12","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1001\/jama.2009.1568","volume":"302","author":"R G\u00e4rtner","year":"2009","unstructured":"G\u00e4rtner R, Jensen M, Nielsen et al (2009) Prevalence of and factors associated with persistent pain following breast cancer surgery. J Am Med Assoc 302(18):1985\u20131992","journal-title":"J Am Med Assoc"},{"issue":"4","key":"2642_CR13","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.jpainsymman.2011.10.021","volume":"44","author":"D Sheridan","year":"2012","unstructured":"Sheridan D, Foo I, O'shea H et al (2012) Long term follow up of pain and emotional characteristics of women after surgery for breast cancer. J Pain Symptom Manag 44(4):608\u2013614","journal-title":"J Pain Symptom Manag"},{"key":"2642_CR14","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.pain.2010.10.026","volume":"152","author":"M Haanpaa","year":"2011","unstructured":"Haanpaa M, Attal N, Backonja M et al (2011) NeuPSIG guidelines on neuropathic pain assessment. Pain 152:4\u201327","journal-title":"Pain"},{"key":"2642_CR15","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1111\/j.1468-1331.2010.02969.x","volume":"17","author":"G Cruccu","year":"2010","unstructured":"Cruccu G, Sommer C, Anand P et al (2010) EFNS guidelines on neuropathic pain assessment: revised 2009. Eur J Neurol 17:1010\u20131018","journal-title":"Eur J Neurol"},{"key":"2642_CR16","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.pain.2006.11.001","volume":"127","author":"BH Smith","year":"2007","unstructured":"Smith BH, Macfarlane GJ, Torrance N (2007) Epidemiology of chronic pain, from the laboratory to the bus stop: time to add understanding of biological mechanisms to the study of risk factors in population-based research? Pain 127:5\u201310","journal-title":"Pain"},{"key":"2642_CR17","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.ejpain.2011.03.005","volume":"15","author":"N Attal","year":"2011","unstructured":"Attal N, Bouhassira D, Baron R et al (2011) Assessing symptom profiles in neuropathic pain clinical trials: can it improve outcome? Eur J Pain 15:441\u2013443","journal-title":"Eur J Pain"},{"key":"2642_CR18","doi-asserted-by":"crossref","first-page":"S107","DOI":"10.1016\/j.pain.2010.11.008","volume":"152","author":"RH Dworkin","year":"2011","unstructured":"Dworkin RH, Turk DC, Katz NP et al (2011) Evidence-based clinical trial design for chronic pain pharmacotherapy: a blueprint for ACTION. Pain 152:S107\u2013S115","journal-title":"Pain"},{"key":"2642_CR19","volume-title":"Drug class review: neuropathic pain. Update 1 final report. Prepared by the Oregon Evidence-based Practice Center for the Drug Effectiveness Review Project","author":"S Selph","year":"2011","unstructured":"Selph S, Carson S, Fu R, Thakurta S et al (2011) Drug class review: neuropathic pain. Update 1 final report. Prepared by the Oregon Evidence-based Practice Center for the Drug Effectiveness Review Project. Oregon Health and Science University, Portland"},{"key":"2642_CR20","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/978-94-007-0265-3_10","volume":"704","author":"Y Liu","year":"2011","unstructured":"Liu Y, Qin N (2011) TRPM8 in health and disease: cold sensing and beyond. Adv Exp Med Biol 704:185\u2013208","journal-title":"Adv Exp Med Biol"},{"key":"2642_CR21","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/978-3-540-79090-7_8","volume":"194","author":"SR Eid","year":"2009","unstructured":"Eid SR, Cortright DN (2009) Transient receptor potential channels on sensory nerves. Handb Exp Pharmacol 194:261\u2013281","journal-title":"Handb Exp Pharmacol"},{"key":"2642_CR22","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1016\/j.cub.2006.07.061","volume":"16","author":"CJ Proudfoot","year":"2006","unstructured":"Proudfoot CJ, Garry EM, Cottrell DF et al (2006) Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain. Curr Biol 16:1591\u20131605","journal-title":"Curr Biol"},{"key":"2642_CR23","doi-asserted-by":"crossref","first-page":"4519","DOI":"10.1200\/JCO.2008.18.5017","volume":"26","author":"LA Colvin","year":"2008","unstructured":"Colvin LA, Johnson PR, Mitchell R et al (2008) From bench to bedside: a case of rapid reversal of bortezomib-induced neuropathic pain by the TRPM8 activator, menthol. J Clin Oncol 26:4519\u20134520","journal-title":"J Clin Oncol"},{"issue":"6","key":"2642_CR24","doi-asserted-by":"crossref","first-page":"e2","DOI":"10.1016\/j.jpainsymman.2010.02.004","volume":"39","author":"DJ Storey","year":"2010","unstructured":"Storey DJ, Colvin LA, MacKean MJ et al (2010) Reversal of dose-limiting carboplatin-induced peripheral neuropathy with TRPM8 activator, menthol, enables further effective chemotherapy delivery. J Pain Symptom Manag 39(6):e2\u2013e4","journal-title":"J Pain Symptom Manag"},{"key":"2642_CR25","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.pain.2010.02.018","volume":"149","author":"RH Dworkin","year":"2010","unstructured":"Dworkin RH, Turk DC, Peirce-Sandner S et al (2010) Research design considerations for confirmatory chronic pain clinical trials: IMMPACT recommendations. Pain 149:177\u2013193","journal-title":"Pain"},{"key":"2642_CR26","first-page":"129","volume":"23","author":"CS Cleeland","year":"1994","unstructured":"Cleeland CS, Ryan KM (1994) Pain assessment: global use of the Brief Pain Inventory. Ann Acad Med Singap 23:129\u2013138","journal-title":"Ann Acad Med Singap"},{"key":"2642_CR27","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","volume":"67","author":"AS Zigmond","year":"1983","unstructured":"Zigmond AS, Snaith RP, Zigmond AS et al (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67:361\u2013370","journal-title":"Acta Psychiatr Scand"},{"key":"2642_CR28","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1037\/1040-3590.7.4.524","volume":"7","author":"M Sullivan","year":"1995","unstructured":"Sullivan M (1995) The Pain Catastrophizing scale: development and validation. Psychol Assess 7:524\u2013532","journal-title":"Psychol Assess"},{"key":"2642_CR29","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0304-3959(00)00482-6","volume":"92","author":"M Bennett","year":"2001","unstructured":"Bennett M (2001) The LANSS pain scale: the leeds assessment of neuropathic symptoms and signs. Pain 92:147\u2013157","journal-title":"Pain"},{"key":"2642_CR30","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1471-2474-5-13","volume":"5","author":"CJ Uden van","year":"2004","unstructured":"van Uden CJ, Besser MP (2004) Test-retest reliability of temporal and spatial gait characteristics measured with an instrumented walkway system (GAITRite). BMC Musculoskelet Disord 5:13","journal-title":"BMC Musculoskelet Disord"},{"key":"2642_CR31","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3109\/02699059309008164","volume":"7","author":"RM Ruff","year":"1993","unstructured":"Ruff RM, Marshall LF, Crouch J et al (1993) Predictors of outcome following severe head trauma: follow-up data from the Traumatic Coma Data Bank. Brain Inj 7:101\u2013111","journal-title":"Brain Inj"},{"key":"2642_CR32","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1006\/brcg.1999.1204","volume":"44","author":"SL Schmidt","year":"2000","unstructured":"Schmidt SL, Oliveira RM, Rocha FR et al (2000) Influences of handedness and gender on the grooved pegboard test. Brain Cogn 44:445\u2013454","journal-title":"Brain Cogn"},{"key":"2642_CR33","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.ejpain.2011.05.002","volume":"16","author":"AC Scott","year":"2002","unstructured":"Scott AC, McConnell S, Laird B et al (2002) Quantitative Sensory Testing to assess the sensory characteristics of cancer-induced bone pain after radiotherapy and potential clinical biomarkers of response. Eur J Pain 16:123\u2013133","journal-title":"Eur J Pain"},{"key":"2642_CR34","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.pain.2006.01.041","volume":"123","author":"R Rolke","year":"2006","unstructured":"Rolke R, Baron R, Maier C et al (2006) Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): standardized protocol and reference values. [erratum appears in Pain. 2006 Nov;125(1-2):197]. Pain 123:231\u2013243","journal-title":"Pain"},{"key":"2642_CR35","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.pain.2009.08.007","volume":"149","author":"RA Moore","year":"2010","unstructured":"Moore RA, Derry S, McQuay HJ et al (2010) Clinical effectiveness: an approach to clinical trial design more relevant to clinical practice, acknowledging the importance of individual differences. Pain 149:173\u2013176","journal-title":"Pain"},{"key":"2642_CR36","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/S0140-6736(02)60091-1","volume":"2464","author":"A Wright","year":"1870","unstructured":"Wright A (1870) Oil of peppermint as a local anaesthetic. Lancet 2464:726","journal-title":"Lancet"},{"issue":"1","key":"2642_CR37","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/nrd2757","volume":"8","author":"A Patapoutian","year":"2009","unstructured":"Patapoutian A, Tate S, Woolf CJ (2009) Transient receptor potential channels: targeting pain at the source. Nat Rev Drug Discov 8(1):55\u201368","journal-title":"Nat Rev Drug Discov"},{"key":"2642_CR38","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/nrd3456","volume":"10","author":"M Moran","year":"2011","unstructured":"Moran M, McAlexander MA, Biro T et al (2011) Targeting receptor potential channels as therapeutic targets. Nat Rev Drug Discov 10:601\u2013620","journal-title":"Nat Rev Drug Discov"},{"issue":"37","key":"2642_CR39","doi-asserted-by":"crossref","first-page":"9874","DOI":"10.1523\/JNEUROSCI.2221-07.2007","volume":"27","author":"Y Karashima","year":"2007","unstructured":"Karashima Y, Damann N, Prenen J et al (2007) Bimodal action of menthol on the transient receptor potential channel TRPA1. J Neurosci 27(37):9874\u20139884","journal-title":"J Neurosci"},{"issue":"2","key":"2642_CR40","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.pain.2011.11.014","volume":"153","author":"C Gaudioso","year":"2012","unstructured":"Gaudioso C, Hao J, Martin-Eauclaire MF et al (2012) Menthol pain relief through cumulative inactivation of voltage-gated sodium channels. Pain 153(2):473\u2013484","journal-title":"Pain"},{"issue":"Pt 5","key":"2642_CR41","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1093\/brain\/awh134","volume":"127","author":"G Wasner","year":"2004","unstructured":"Wasner G, Schattschneider J, Binder A, Baron R (2004) Topical menthol\u2014a human model for cold pain by activation and sensitization of C nociceptors. Brain 127(Pt 5):1159\u20131171","journal-title":"Brain"},{"issue":"1","key":"2642_CR42","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.clinthera.2010.01.016","volume":"32","author":"Y Higashi","year":"2010","unstructured":"Higashi Y, Kiuchi T, Furuta K (2010) Efficacy and safety profile of a topical methyl salicylate and menthol patch in adult patients with mild to moderate muscle strain: a randomized, double-blind, parallel-group, placebo-controlled, multicenter study. Clin Ther 32(1):34\u201343","journal-title":"Clin Ther"},{"issue":"4","key":"2642_CR43","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1111\/j.1742-1241.2009.02215.x","volume":"64","author":"A Borhani Haghighi","year":"2010","unstructured":"Borhani Haghighi A, Motazedian S, Rezaii R et al (2010) Cutaneous application of menthol 10% solution as an abortive treatment of migraine without aura: a randomised, double-blind, placebo-controlled, crossed-over study. Int J Clin Pract 64(4):451\u2013456","journal-title":"Int J Clin Pract"},{"key":"2642_CR44","doi-asserted-by":"crossref","first-page":"a2313","DOI":"10.1136\/bmj.a2313","volume":"337","author":"AC Ford","year":"2008","unstructured":"Ford AC, Talley NJ, Spiegel BM et al (2008) Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis. BMJ 337:a2313","journal-title":"BMJ"},{"key":"2642_CR45","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/S1474-4422(10)70143-5","volume":"9","author":"R Baron","year":"2010","unstructured":"Baron R, Binder A, Wasner G (2010) Neuropathic pain: assessment, understanding and treatment. Lancet Neurol 9:807\u2013819","journal-title":"Lancet Neurol"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-015-2642-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00520-015-2642-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-015-2642-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,26]],"date-time":"2019-03-26T18:51:51Z","timestamp":1553626311000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00520-015-2642-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,15]]},"references-count":45,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["2642"],"URL":"https:\/\/doi.org\/10.1007\/s00520-015-2642-8","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,15]]}}}