{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T15:08:58Z","timestamp":1788966538598,"version":"build-2803163510"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["U54-CA155850"],"award-info":[{"award-number":["U54-CA155850"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1007\/s00520-015-3029-6","type":"journal-article","created":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T03:05:35Z","timestamp":1448939135000},"page":"2333-2340","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Post-treatment weight change in oral cavity and oropharyngeal squamous cell carcinoma"],"prefix":"10.1007","volume":"24","author":[{"given":"Zi","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin C.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Bert W.","family":"O\u2019Malley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea B.","family":"Troxel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua M.","family":"Bauml","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaitlyn R.","family":"Rubnitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen M.","family":"Grosso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory S.","family":"Weinstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn H.","family":"Schmitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,12,1]]},"reference":[{"issue":"3","key":"3029_CR1","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1046\/j.1365-2354.1999.00156.x","volume":"8","author":"J Lees","year":"1999","unstructured":"Lees J (1999) Incidence of weight loss in head and neck cancer patients on commencing radiotherapy treatment at a regional oncology centre. Eur J Cancer Care (Engl) 8(3):133\u2013136","journal-title":"Eur J Cancer Care (Engl)"},{"issue":"4","key":"3029_CR2","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1002\/hed.20447","volume":"29","author":"M Couch","year":"2007","unstructured":"Couch M et al (2007) Cancer cachexia syndrome in head and neck cancer patients: part I. Diagnosis, impact on quality of life and survival, and treatment. Head Neck 29(4):401\u2013411","journal-title":"Head Neck"},{"issue":"4","key":"3029_CR3","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1200\/JCO.2007.14.1713","volume":"26","author":"AK Chaturvedi","year":"2008","unstructured":"Chaturvedi AK et al (2008) Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States. J Clin Oncol 26(4):612\u2013619","journal-title":"J Clin Oncol"},{"issue":"6","key":"3029_CR4","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1053\/j.seminoncol.2004.09.011","volume":"31","author":"ML Gillison","year":"2004","unstructured":"Gillison ML (2004) Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity. Semin Oncol 31(6):744\u2013754","journal-title":"Semin Oncol"},{"issue":"32","key":"3029_CR5","doi-asserted-by":"publisher","first-page":"4294","DOI":"10.1200\/JCO.2011.36.4596","volume":"29","author":"AK Chaturvedi","year":"2011","unstructured":"Chaturvedi AK et al (2011) Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol 29(32):4294\u20134301","journal-title":"J Clin Oncol"},{"issue":"6","key":"3029_CR6","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1002\/(SICI)1097-0347(199709)19:6<494::AID-HED6>3.0.CO;2-U","volume":"19","author":"M Machtay","year":"1997","unstructured":"Machtay M et al (1997) Combined surgery and postoperative radiotherapy for carcinoma of the base of radiotherapy for carcinoma of the base of tongue: analysis of treatment outcome and prognostic value of margin status. Head Neck 19(6):494\u2013499","journal-title":"Head Neck"},{"issue":"1","key":"3029_CR7","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.radonc.2009.04.014","volume":"92","author":"JP Pignon","year":"2009","unstructured":"Pignon JP et al (2009) Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients. Radiother Oncol 92(1):4\u201314","journal-title":"Radiother Oncol"},{"issue":"21","key":"3029_CR8","doi-asserted-by":"publisher","first-page":"3582","DOI":"10.1200\/JCO.2007.14.8841","volume":"26","author":"M Machtay","year":"2008","unstructured":"Machtay M et al (2008) Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis. J Clin Oncol 26(21):3582\u20133589","journal-title":"J Clin Oncol"},{"issue":"8","key":"3029_CR9","doi-asserted-by":"publisher","first-page":"1465","DOI":"10.1097\/01.mlg.0000227184.90514.1a","volume":"116","author":"BW O\u2019Malley Jr","year":"2006","unstructured":"O\u2019Malley BW Jr et al (2006) Transoral robotic surgery (TORS) for base of tongue neoplasms. Laryngoscope 116(8):1465\u20131472","journal-title":"Laryngoscope"},{"issue":"12","key":"3029_CR10","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.1001\/archotol.133.12.1220","volume":"133","author":"GS Weinstein","year":"2007","unstructured":"Weinstein GS et al (2007) Transoral robotic surgery: radical tonsillectomy. Arch Otolaryngol Head Neck Surg 133(12):1220\u20131226","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"11","key":"3029_CR11","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1001\/archoto.2010.191","volume":"136","author":"GS Weinstein","year":"2010","unstructured":"Weinstein GS et al (2010) Transoral robotic surgery for advanced oropharyngeal carcinoma. Arch Otolaryngol Head Neck Surg 136(11):1079\u20131085","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"9","key":"3029_CR12","first-page":"1356","volume":"36","author":"W Jackson","year":"2014","unstructured":"Jackson W et al (2014) Characterization of changes in total body composition for head and neck cancer patients undergoing chemoradiotherapy using dual-energy x-ray absorptiometry (DEXA). Head Neck 36(9):1356\u20131362","journal-title":"Head Neck"},{"key":"3029_CR13","doi-asserted-by":"publisher","first-page":"711","DOI":"10.3109\/0284186X.2012.731524","volume":"52","author":"S Ottosson","year":"2013","unstructured":"Ottosson S et al (2013) Weight loss in patients with head and neck cancer during and after conventional and accelerated radiotherapy. Acta Oncol 52:711","journal-title":"Acta Oncol"},{"key":"3029_CR14","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1007\/s00520-006-0212-9","volume":"15","author":"H Jager-Wittenaar","year":"2007","unstructured":"Jager-Wittenaar H et al (2007) Critical weight loss in head and neck cancer\u2014prevalence and risk factors at diagnosis: an explorative study. Support Care Cancer 15:1045","journal-title":"Support Care Cancer"},{"key":"3029_CR15","first-page":"CD007904","volume":"3","author":"B Nugent","year":"2010","unstructured":"Nugent B, Lewis S, O\u2019Sullivan JM (2010) Enteral feeding methods for nutritional management in patients with head and neck cancers being treated with radiotherapy and\/or chemotherapy. Cochrane Database Syst Rev 3:CD007904","journal-title":"Cochrane Database Syst Rev"},{"issue":"9","key":"3029_CR16","first-page":"1356","volume":"36","author":"W Jackson","year":"2013","unstructured":"Jackson W et al (2013) Characterization of changes in total body composition for patients with head and neck cancer undergoing chemoradiotherapy using dual-energy x-ray absorptiometry. Head Neck 36(9):1356\u20131362","journal-title":"Head Neck"},{"issue":"5","key":"3029_CR17","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","volume":"40","author":"ME Charlson","year":"1987","unstructured":"Charlson ME et al (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40(5):373\u2013383","journal-title":"J Chronic Dis"},{"key":"3029_CR18","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1080\/01635581.2013.741749","volume":"65","author":"JAE Langius","year":"2013","unstructured":"Langius JAE et al (2013) More than 10\u00a0% weight loss in head and neck cancer patients during radiotherapy is independently associated with deterioration in quality of life. Nutr Cancer 65:76","journal-title":"Nutr Cancer"},{"key":"3029_CR19","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1038\/bjc.2013.458","volume":"109","author":"J Langius","year":"2013","unstructured":"Langius J et al (2013) Critical weight loss is a major prognostic indicator for disease-specific survival in patients with head and neck cancer receiving radiotherapy. Br J Cancer 109:1093","journal-title":"Br J Cancer"},{"issue":"5","key":"3029_CR20","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1001\/jama.2012.39","volume":"307","author":"KM Flegal","year":"2012","unstructured":"Flegal KM et al (2012) Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. JAMA 307(5):491\u2013497","journal-title":"JAMA"},{"key":"3029_CR21","unstructured":"NCCN Guidelines Version 2.2013 Panel. National Comprehensive Cancer Network Clinical Practice Guidelines for Head and Neck Cancer. 2013; Version 2:[Available from: \n                    http:\/\/oralcancerfoundation.org\/treatment\/pdf\/head-and-neck.pdf"},{"key":"3029_CR22","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1001\/archotol.124.5.589","volume":"124","author":"A Lisa","year":"1998","unstructured":"Lisa A, Newman S et al (1998) Eating and weight changes following chemoradiation therapy for advanced head and neck cancer. Arch Otolaryngol Head Neck Surg 124:589","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"3029_CR23","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1007\/s00520-011-1146-4","volume":"20","author":"YT Ehrsson","year":"2012","unstructured":"Ehrsson YT, Langius-Eklof A, Laurell G (2012) Nutritional surveillance and weight loss in head and neck cancer patients. Support Care Cancer 20:757","journal-title":"Support Care Cancer"},{"issue":"6","key":"3029_CR24","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1067\/mhn.2001.120428","volume":"125","author":"M Beaver","year":"2001","unstructured":"Beaver M et al (2001) Predictors of weight loss during radiation therapy. Otolaryngol Head Neck Surg 125(6):645\u2013648","journal-title":"Otolaryngol Head Neck Surg"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-015-3029-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00520-015-3029-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-015-3029-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-015-3029-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T15:20:18Z","timestamp":1589642418000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00520-015-3029-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,1]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["3029"],"URL":"https:\/\/doi.org\/10.1007\/s00520-015-3029-6","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,1]]},"assertion":[{"value":"20 May 2015","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 November 2015","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 December 2015","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The research for this manuscript was supported in part by the National Institutes of Health (U54-CA155850) awarded to K.H.S., and J.C.B. and Z.Z. were funded under the U54-CA155850. The opinions and conclusions of the authors are not necessarily those of the sponsoring agency. B.W.O. and G.S.W. receive royalties from Olympus Corporation through the University of Pennsylvania. All the other authors did not report any conflicts of interest. The first author and corresponding authors have full control of all primary data and agree to allow the journal to review the data if requested.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}