{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T06:33:40Z","timestamp":1793255620213,"version":"4.5.0"},"reference-count":101,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2016,3,16]],"date-time":"2016-03-16T00:00:00Z","timestamp":1458086400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2016,3,16]],"date-time":"2016-03-16T00:00:00Z","timestamp":1458086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["grant R01AI050875."],"award-info":[{"award-number":["grant R01AI050875."]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1007\/s00520-016-3152-z","type":"journal-article","created":{"date-parts":[[2016,3,18]],"date-time":"2016-03-18T12:34:53Z","timestamp":1458304493000},"page":"2781-2792","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":185,"title":["Low level laser therapy\/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 1: mechanisms of action, dosimetric, and safety considerations"],"prefix":"10.1007","volume":"24","author":[{"given":"Judith A. E. M.","family":"Zecha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith E.","family":"Raber-Durlacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raj G.","family":"Nair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel B.","family":"Epstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen T.","family":"Sonis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Elad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Hamblin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Barasch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesar A.","family":"Migliorati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan M. J.","family":"Milstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Th\u00e9r\u00e8se","family":"Genot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liset","family":"Lansaat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron","family":"van der Brink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Arnabat-Dominguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisette","family":"van der Molen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Jacobi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judi","family":"van Diessen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"de Lange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludi E.","family":"Smeele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark M.","family":"Schubert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9-Jean","family":"Bensadoun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,3,16]]},"reference":[{"key":"3152_CR1","doi-asserted-by":"publisher","first-page":"400","DOI":"10.3322\/caac.21157","volume":"62","author":"JB Epstein","year":"2012","unstructured":"Epstein JB, Thariat J, Bensadoun RJ, Barasch A, Murphy BA, Kolnick L, Popplewell L, Maghami E (2012) Oral complications of cancer and cancer therapy: from cancer treatment to survivorship. CA Cancer J Clin 62:400\u2013422. doi:\n                    10.3322\/caac.21157","journal-title":"CA Cancer J Clin"},{"key":"3152_CR2","doi-asserted-by":"publisher","first-page":"2636","DOI":"10.1200\/JCO.2006.06.0079","volume":"24","author":"DI Rosenthal","year":"2006","unstructured":"Rosenthal DI, Lewin JS, Eisbruch A (2006) Prevention and treatment of dysphagia and aspiration after chemoradiation for head and neck cancer. J. Clin.Oncol. 24:2636\u20132643. doi:\n                    10.1200\/JCO.2006.06.0079","journal-title":"J. Clin.Oncol."},{"key":"3152_CR3","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1007\/s00405-008-0817-3","volume":"266","author":"L van der Molen","year":"2009","unstructured":"van der Molen L, van Rossum MA, Burkhead LM, Smeele LE, Hilgers FJ (2009) Functional outcomes and rehabilitation strategies in patients treated with chemoradiotherapy for advanced head and neck cancer: a systematic review. Eur Arch Otorhinolaryngol 266:889\u2013900. doi:\n                    10.1007\/s00405-008-0817-3","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"3152_CR4","doi-asserted-by":"publisher","first-page":"156","DOI":"10.2174\/157488708785700285","volume":"3","author":"AD Rapidis","year":"2008","unstructured":"Rapidis AD, Vermorken JB, Bourhis J (2008) Targeted therapies in head and neck cancer: past, present and future. Rev Recent Clin Trials 3:156\u2013166","journal-title":"Rev Recent Clin Trials"},{"key":"3152_CR5","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/j.oraloncology.2011.03.028","volume":"47","author":"AL Watters","year":"2011","unstructured":"Watters AL, Epstein JB, Agulnik M (2011) Oral complications of targeted cancer therapies: a narrative literature review. Oral Oncol 47:441\u2013448. doi:\n                    10.1016\/j.oraloncology.2011.03.028","journal-title":"Oral Oncol"},{"key":"3152_CR6","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1007\/s00520-011-1197-6","volume":"19","author":"ME Lacouture","year":"2011","unstructured":"Lacouture ME, Anadkat MJ, Bensadoun RJ, Bryce J, Chan A, Epstein JB, Eaby-Sandy B, Murphy BA (2011) Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities. Support. Care Cancer 19:1079\u20131095. doi:\n                    10.1007\/s00520-011-1197-6","journal-title":"Support. Care Cancer"},{"key":"3152_CR7","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1177\/154411130301400305","volume":"14","author":"A Vissink","year":"2003","unstructured":"Vissink A, Jansma J, Spijkervet FK, Burlage FR, Coppes RP (2003) Oral sequelae of head and neck radiotherapy. Crit Rev Oral Biol Med 14:199\u2013212","journal-title":"Crit Rev Oral Biol Med"},{"key":"3152_CR8","unstructured":"WALT\/NAALT (September 9\u201312 2014) Photobiomodulation: mainstream medicine and beyond. WALT Biennial Congress and NAALT Annual Conference, Arlington Virginia USA"},{"key":"3152_CR9","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1016\/0002-9610(71)90482-X","volume":"122","author":"E Mester","year":"1971","unstructured":"Mester E, Spiry T, Szende B, Tota JG (1971) Effect of laser rays on wound healing. Am J Surg 122:532\u2013535","journal-title":"Am J Surg"},{"key":"3152_CR10","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1161\/01.CIR.103.2.296","volume":"103","author":"U Oron","year":"2001","unstructured":"Oron U, Yaakobi T, Oron A, Mordechovitz D, Shofti R, Hayam G, Dror U, Gepstein L, Wolf T, Haudenschild C, Haim SB (2001) Low-energy laser irradiation reduces formation of scar tissue after myocardial infarction in rats and dogs. Circulation 103:296\u2013301","journal-title":"Circulation"},{"key":"3152_CR11","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1002\/lsm.20371","volume":"38","author":"CF Rizzi","year":"2006","unstructured":"Rizzi CF, Mauriz JL, Freitas Correa DS, Moreira AJ, Zettler CG, Filippin LI, Marroni NP, Gonzalez-Gallego J (2006) Effects of low-level laser therapy (LLLT) on the nuclear factor (NF)-kappaB signaling pathway in traumatized muscle. Lasers Surg Med 38:704\u2013713. doi:\n                    10.1002\/lsm.20371","journal-title":"Lasers Surg Med"},{"key":"3152_CR12","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1002\/lsm.20952","volume":"42","author":"D Barolet","year":"2010","unstructured":"Barolet D, Boucher A (2010) Prophylactic low-level light therapy for the treatment of hypertrophic scars and keloids: a case series. Lasers Surg Med 42:597\u2013601. doi:\n                    10.1002\/lsm.20952","journal-title":"Lasers Surg Med"},{"key":"3152_CR13","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1089\/pho.2012.3272","volume":"30","author":"FA Oliveira","year":"2012","unstructured":"Oliveira FA, Moraes AC, Paiva AP, Schinzel V, Correa-Costa M, Semedo P, Castoldi A, Cenedeze MA, Oliveira RS, Bastos MG, Camara NO, Sanders-Pinheiro H (2012) Low-level laser therapy decreases renal interstitial fibrosis. Photomed Laser Surg 30:705\u2013713. doi:\n                    10.1089\/pho.2012.3272","journal-title":"Photomed Laser Surg"},{"key":"3152_CR14","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1007\/s10103-012-1163-7","volume":"28","author":"DT Meneguzzo","year":"2013","unstructured":"Meneguzzo DT, Lopes LA, Pallota R, Soares-Ferreira L, Lopes-Martins RA, Ribeiro MS (2013) Prevention and treatment of mice paw edema by near-infrared low-level laser therapy on lymph nodes. Lasers Med Sci 28:973\u2013980. doi:\n                    10.1007\/s10103-012-1163-7","journal-title":"Lasers Med Sci"},{"key":"3152_CR15","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1007\/s10103-012-1133-0","volume":"28","author":"L Luo","year":"2013","unstructured":"Luo L, Sun Z, Zhang L, Li X, Dong Y, Liu TC (2013) Effects of low-level laser therapy on ROS homeostasis and expression of IGF-1 and TGF-beta1 in skeletal muscle during the repair process. Lasers Med Sci 28:725\u2013734. doi:\n                    10.1007\/s10103-012-1133-0","journal-title":"Lasers Med Sci"},{"key":"3152_CR16","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/S0004-9514(14)60127-6","volume":"49","author":"JM Bjordal","year":"2003","unstructured":"Bjordal JM, Couppe C, Chow RT, Tuner J, Ljunggren EA (2003) A systematic review of low level laser therapy with location-specific doses for pain from chronic joint disorders. Aust. J. Physiother. 49:107\u2013116","journal-title":"Aust. J. Physiother."},{"key":"3152_CR17","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1089\/pho.2006.24.158","volume":"24","author":"JM Bjordal","year":"2006","unstructured":"Bjordal JM, Johnson MI, Iversen V, Aimbire F, Lopes-Martins RA (2006) Low-level laser therapy in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials. Photomed Laser Surg 24:158\u2013168. doi:\n                    10.1089\/pho.2006.24.158","journal-title":"Photomed Laser Surg"},{"key":"3152_CR18","doi-asserted-by":"publisher","first-page":"1897","DOI":"10.1016\/S0140-6736(09)61522-1","volume":"374","author":"RT Chow","year":"2009","unstructured":"Chow RT, Johnson MI, Lopes-Martins RA, Bjordal JM (2009) Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials. Lancet 374:1897\u20131908. doi:\n                    10.1016\/S0140-6736(09)61522-1","journal-title":"Lancet"},{"key":"3152_CR19","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1089\/pho.2010.2928","volume":"29","author":"R Chow","year":"2011","unstructured":"Chow R, Armati P, Laakso EL, Bjordal JM, Baxter GD (2011) Inhibitory effects of laser irradiation on peripheral mammalian nerves and relevance to analgesic effects: a systematic review. Photomed Laser Surg 29:365\u2013381. doi:\n                    10.1089\/pho.2010.2928","journal-title":"Photomed Laser Surg"},{"key":"3152_CR20","doi-asserted-by":"crossref","unstructured":"Clarkson JE, Worthington HV, Furness S, McCabe M, Khalid T and Meyer S (2010) Interventions for treating oral mucositis for patients with cancer receiving treatment. Cochrane. Database. Syst.Rev.:CD001973. doi:10.1002\/14651858.CD001973.pub4","DOI":"10.1002\/14651858.CD001973.pub4"},{"key":"3152_CR21","doi-asserted-by":"crossref","unstructured":"Worthington HV, Clarkson JE, Bryan G, Furness S, Glenny AM, Littlewood A, McCabe MG, Meyer S and Khalid T (2011) Interventions for preventing oral mucositis for patients with cancer receiving treatment. Cochrane. Database. Syst.Rev.:CD000978. doi:10.1002\/14651858.CD000978.pub5","DOI":"10.1002\/14651858.CD000978.pub5"},{"key":"3152_CR22","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1007\/s00520-011-1202-0","volume":"19","author":"JM Bjordal","year":"2011","unstructured":"Bjordal JM, Bensadoun RJ, Tuner J, Frigo L, Gjerde K, Lopes-Martins RA (2011) A systematic review with meta-analysis of the effect of low-level laser therapy (LLLT) in cancer therapy-induced oral mucositis. Support Care Cancer 19:1069\u20131077. doi:\n                    10.1007\/s00520-011-1202-0","journal-title":"Support Care Cancer"},{"key":"3152_CR23","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1097\/CCO.0b013e328352eaa3","volume":"24","author":"RJ Bensadoun","year":"2012","unstructured":"Bensadoun RJ, Nair RG (2012) Low-level laser therapy in the prevention and treatment of cancer therapy-induced mucositis: 2012 state of the art based on literature review and meta-analysis. Curr Opin Oncol 24:363\u2013370. doi:\n                    10.1097\/CCO.0b013e328352eaa3","journal-title":"Curr Opin Oncol"},{"key":"3152_CR24","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1007\/s00520-012-1605-6","volume":"21","author":"C Migliorati","year":"2013","unstructured":"Migliorati C, Hewson I, Lalla RV, Antunes HS, Estilo CL, Hodgson B, Lopes NN, Schubert MM, Bowen J, Elad S (2013) Systematic review of laser and other light therapy for the management of oral mucositis in cancer patients. Support Care Cancer 21:333\u2013341. doi:\n                    10.1007\/s00520-012-1605-6","journal-title":"Support Care Cancer"},{"key":"3152_CR25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0107418","volume":"9","author":"S Oberoi","year":"2014","unstructured":"Oberoi S, Zamperlini-Netto G, Beyene J, Treister NS, Sung L (2014) Effect of prophylactic low level laser therapy on oral mucositis: a systematic review and meta-analysis. PLoS one 9:e107418. doi:\n                    10.1371\/journal.pone.0107418","journal-title":"PLoS one"},{"key":"3152_CR26","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1007\/s00520-011-1223-8","volume":"20","author":"BD Hodgson","year":"2012","unstructured":"Hodgson BD, Margolis DM, Salzman DE, Eastwood D, Tarima S, Williams LD, Sande JE, Vaughan WP, Whelan HT (2012) Amelioration of oral mucositis pain by NASA near-infrared light-emitting diodes in bone marrow transplant patients. Support Care Cancer 20:1405\u20131415. doi:\n                    10.1007\/s00520-011-1223-8","journal-title":"Support Care Cancer"},{"key":"3152_CR27","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1089\/pho.2012.3284","volume":"31","author":"DE Hudson","year":"2013","unstructured":"Hudson DE, Hudson DO, Wininger JM, Richardson BD (2013) Penetration of laser light at 808 and 980\u00a0nm in bovine tissue samples. Photomed Laser Surg 31:163\u2013168. doi:\n                    10.1089\/pho.2012.3284","journal-title":"Photomed Laser Surg"},{"key":"3152_CR28","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1002\/lsm.20950","volume":"42","author":"JT Hashmi","year":"2010","unstructured":"Hashmi JT, Huang YY, Sharma SK, Kurup DB, De TL, Carroll JD, Hamblin MR (2010) Effect of pulsing in low-level light therapy. Lasers Surg Med 42:450\u2013466. doi:\n                    10.1002\/lsm.20950","journal-title":"Lasers Surg Med"},{"key":"3152_CR29","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1089\/pho.2005.23.251","volume":"23","author":"D Hawkins","year":"2005","unstructured":"Hawkins D, Abrahamse H (2005) Biological effects of helium-neon laser irradiation on normal and wounded human skin fibroblasts. Photomed Laser Surg 23:251\u2013259. doi:\n                    10.1089\/pho.2005.23.251","journal-title":"Photomed Laser Surg"},{"key":"3152_CR30","doi-asserted-by":"crossref","unstructured":"Karu TI (2010) Multiple roles of cytochrome c oxidase in mammalian cells under action of red and IR-A radiation. IUBMB.Life 62:607\u2013610. doi:10.1002\/iub.359","DOI":"10.1002\/iub.359"},{"issue":"84\u201390","key":"3152_CR31","first-page":"92","volume":"301","author":"BS Khakh","year":"2009","unstructured":"Khakh BS, Burnstock G (2009) The double life of ATP. Sci.Am. 301(84\u201390):92","journal-title":"Sci.Am."},{"key":"3152_CR32","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1042\/bj2650659","volume":"265","author":"GA Murrell","year":"1990","unstructured":"Murrell GA, Francis MJ, Bromley L (1990) Modulation of fibroblast proliferation by oxygen free radicals. Biochem.J. 265:659\u2013665","journal-title":"Biochem.J."},{"key":"3152_CR33","doi-asserted-by":"publisher","unstructured":"Antunes F, Boveris A and Cadenas E (2004) On the mechanism and biology of cytochrome oxidase inhibition by nitric oxide. Proc.Natl.Acad.Sci.U.S.A 101:16774\u201316779. doi:\n                    10.1073\/pnas.0405368101","DOI":"10.1073\/pnas.0405368101"},{"key":"3152_CR34","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1007\/s10439-011-0454-7","volume":"40","author":"H Chung","year":"2012","unstructured":"Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR (2012) The nuts and bolts of low-level laser (light) therapy. Ann.Biomed.Eng 40:516\u2013533. doi:\n                    10.1007\/s10439-011-0454-7","journal-title":"Ann.Biomed.Eng"},{"key":"3152_CR35","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1089\/pho.2005.23.355","volume":"23","author":"TI Karu","year":"2005","unstructured":"Karu TI, Kolyakov SF (2005) Exact action spectra for cellular responses relevant to phototherapy. Photomed.Laser Surg. 23:355\u2013361. doi:\n                    10.1089\/pho.2005.23.355","journal-title":"Photomed.Laser Surg."},{"key":"3152_CR36","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1097\/00004032-198905000-00015","volume":"56","author":"T Karu","year":"1989","unstructured":"Karu T (1989) Photobiology of low-power laser effects. Health Phys 56:691\u2013704","journal-title":"Health Phys"},{"key":"3152_CR37","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1002\/lsm.22077","volume":"44","author":"L Assis","year":"2012","unstructured":"Assis L, Moretti AI, Abrahao TB, Cury V, Souza HP, Hamblin MR, Parizotto NA (2012) Low-level laser therapy (808\u00a0nm) reduces inflammatory response and oxidative stress in rat tibialis anterior muscle after cryolesion. Lasers Surg.Med. 44:726\u2013735. doi:\n                    10.1002\/lsm.22077","journal-title":"Lasers Surg.Med."},{"key":"3152_CR38","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1039\/b306126d","volume":"3","author":"TI Karu","year":"2004","unstructured":"Karu TI, Pyatibrat LV, Kalendo GS (2004) Photobiological modulation of cell attachment via cytochrome c oxidase. Photochem.Photobiol.Sci. 3:211\u2013216. doi:\n                    10.1039\/b306126d","journal-title":"Photochem.Photobiol.Sci."},{"key":"3152_CR39","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1089\/104454703321895635","volume":"21","author":"Y Fujimaki","year":"2003","unstructured":"Fujimaki Y, Shimoyama T, Liu Q, Umeda T, Nakaji S, Sugawara K (2003) Low-level laser irradiation attenuates production of reactive oxygen species by human neutrophils. J.Clin.Laser Med.Surg. 21:165\u2013170. doi:\n                    10.1089\/104454703321895635","journal-title":"J.Clin.Laser Med.Surg."},{"key":"3152_CR40","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1007\/s10103-012-1075-6","volume":"28","author":"PC Silveira","year":"2013","unstructured":"Silveira PC, da Silva LA, Pinho CA, De Souza PS, Ronsani MM, Scheffer DL, Pinho RA (2013) Effects of low-level laser therapy (GaAs) in an animal model of muscular damage induced by trauma. Lasers Med.Sci. 28:431\u2013436. doi:\n                    10.1007\/s10103-012-1075-6","journal-title":"Lasers Med.Sci."},{"key":"3152_CR41","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1002\/lsm.21053","volume":"43","author":"FM de Lima","year":"2011","unstructured":"de Lima FM, Villaverde AB, Albertini R, Correa JC, Carvalho RL, Munin E, Araujo T, Silva JA, Aimbire F (2011) Dual effect of low-level laser therapy (LLLT) on the acute lung inflammation induced by intestinal ischemia and reperfusion: action on anti- and pro-inflammatory cytokines. Lasers Surg.Med. 43:410\u2013420. doi:\n                    10.1002\/lsm.21053","journal-title":"Lasers Surg.Med."},{"key":"3152_CR42","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/j.yjmcc.2009.03.009","volume":"47","author":"NL Lohr","year":"2009","unstructured":"Lohr NL, Keszler A, Pratt P, Bienengraber M, Warltier DC, Hogg N (2009) Enhancement of nitric oxide release from nitrosyl hemoglobin and nitrosyl myoglobin by red\/near infrared radiation: potential role in cardioprotection. J.Mol.Cell Cardiol. 47:256\u2013263. doi:\n                    10.1016\/j.yjmcc.2009.03.009","journal-title":"J.Mol.Cell Cardiol."},{"key":"3152_CR43","doi-asserted-by":"publisher","first-page":"1409","DOI":"10.1007\/s00520-009-0603-9","volume":"17","author":"NN Lopes","year":"2009","unstructured":"Lopes NN, Plapler H, Chavantes MC, Lalla RV, Yoshimura EM, Alves MT (2009) Cyclooxygenase-2 and vascular endothelial growth factor expression in 5-fluorouracil-induced oral mucositis in hamsters: evaluation of two low-intensity laser protocols. Support Care Cancer 17:1409\u20131415. doi:\n                    10.1007\/s00520-009-0603-9","journal-title":"Support Care Cancer"},{"key":"3152_CR44","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1002\/lsm.20920","volume":"42","author":"NN Lopes","year":"2010","unstructured":"Lopes NN, Plapler H, Lalla RV, Chavantes MC, Yoshimura EM, da Silva MA, Alves MT (2010) Effects of low-level laser therapy on collagen expression and neutrophil infiltrate in 5-fluorouracil-induced oral mucositis in hamsters. Lasers Surg.Med. 42:546\u2013552. doi:\n                    10.1002\/lsm.20920","journal-title":"Lasers Surg.Med."},{"key":"3152_CR45","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1002\/ssu.2980110311","volume":"11","author":"WM Mendenhall","year":"1995","unstructured":"Mendenhall WM, Parsons JT, Buatti JM, Stringer SP, Million RR, Cassisi NJ (1995) Advances in radiotherapy for head and neck cancer. Semin.Surg.Oncol. 11:256\u2013264","journal-title":"Semin.Surg.Oncol."},{"key":"3152_CR46","doi-asserted-by":"publisher","first-page":"51","DOI":"10.3389\/fphar.2014.00051","volume":"5","author":"ML Mancini","year":"2014","unstructured":"Mancini ML, Sonis ST (2014) Mechanisms of cellular fibrosis associated with cancer regimen-related toxicities. Front Pharmacol 5:51. doi:\n                    10.3389\/fphar.2014.00051","journal-title":"Front Pharmacol"},{"key":"3152_CR47","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1002\/lsm.20225","volume":"37","author":"LI Fillipin","year":"2005","unstructured":"Fillipin LI, Mauriz JL, Vedovelli K, Moreira AJ, Zettler CG, Lech O, Marroni NP, Gonzalez-Gallego J (2005) Low-level laser therapy (LLLT) prevents oxidative stress and reduces fibrosis in rat traumatized Achilles tendon. Lasers Surg Med 37:293\u2013300. doi:\n                    10.1002\/lsm.20225","journal-title":"Lasers Surg Med"},{"key":"3152_CR48","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1111\/dsu.12087","volume":"39","author":"H Lev-Tov","year":"2013","unstructured":"Lev-Tov H, Brody N, Siegel D, Jagdeo J (2013) Inhibition of fibroblast proliferation in vitro using low-level infrared light-emitting diodes. Dermatol.Surg. 39:422\u2013425. doi:\n                    10.1111\/dsu.12087","journal-title":"Dermatol.Surg."},{"key":"3152_CR49","doi-asserted-by":"publisher","first-page":"358","DOI":"10.2203\/dose-response.09-027.Hamblin","volume":"7","author":"YY Huang","year":"2009","unstructured":"Huang YY, Chen AC, Carroll JD, Hamblin MR (2009) Biphasic dose response in low level light therapy. Dose.Response 7:358\u2013383. doi:\n                    10.2203\/dose-response.09-027.Hamblin","journal-title":"Dose.Response"},{"key":"3152_CR50","doi-asserted-by":"publisher","first-page":"602","DOI":"10.2203\/dose-response.11-009.Hamblin","volume":"9","author":"YY Huang","year":"2011","unstructured":"Huang YY, Sharma SK, Carroll J, Hamblin MR (2011) Biphasic dose response in low level light therapy\u2014an update. Dose.Response 9:602\u2013618. doi:\n                    10.2203\/dose-response.11-009.Hamblin","journal-title":"Dose.Response"},{"key":"3152_CR51","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1089\/104454701750066910","volume":"19","author":"AP Sommer","year":"2001","unstructured":"Sommer AP, Pinheiro AL, Mester AR, Franke RP, Whelan HT (2001) Biostimulatory windows in low-intensity laser activation: lasers, scanners, and NASA\u2019s light-emitting diode array system. J.Clin.Laser Med.Surg. 19:29\u201333. doi:\n                    10.1089\/104454701750066910","journal-title":"J.Clin.Laser Med.Surg."},{"key":"3152_CR52","unstructured":"(WALT) WAfLT \n                    www.waltza.co.za\n                    \n                  ."},{"key":"3152_CR53","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1089\/pho.2012.9893","volume":"30","author":"JM Bjordal","year":"2012","unstructured":"Bjordal JM (2012) Low level laser therapy (LLLT) and World Association for Laser Therapy (WALT) dosage recommendations. Photomed Laser Surg 30:61\u201362. doi:\n                    10.1089\/pho.2012.9893","journal-title":"Photomed Laser Surg"},{"key":"3152_CR54","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1089\/pho.2011.9895","volume":"29","author":"PA Jenkins","year":"2011","unstructured":"Jenkins PA, Carroll JD (2011) How to report low-level laser therapy (LLLT)\/photomedicine dose and beam parameters in clinical and laboratory studies. Photomed.Laser Surg. 29:785\u2013787. doi:\n                    10.1089\/pho.2011.9895","journal-title":"Photomed.Laser Surg."},{"key":"3152_CR55","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1089\/pho.2008.2361","volume":"27","author":"RR Guirro","year":"2009","unstructured":"Guirro RR, Weis LC (2009) Radiant power determination of low-level laser therapy equipment and characterization of its clinical use procedures. Photomed.Laser Surg. 27:633\u2013639. doi:\n                    10.1089\/pho.2008.2361","journal-title":"Photomed.Laser Surg."},{"key":"3152_CR56","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1007\/s10103-014-1535-2","volume":"29","author":"AC Gomes Henriques","year":"2014","unstructured":"Gomes Henriques AC, Ginani F, Oliveira RM, Keesen TS, Galvao Barboza CA, Oliveira Rocha HA, de Castro JF, Della Coletta R, de Almeida FR (2014) Low-level laser therapy promotes proliferation and invasion of oral squamous cell carcinoma cells. Lasers Med Sci 29:1385\u20131395. doi:\n                    10.1007\/s10103-014-1535-2","journal-title":"Lasers Med Sci"},{"key":"3152_CR57","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.oraloncology.2014.11.012","volume":"51","author":"DR Simpson","year":"2015","unstructured":"Simpson DR, Mell LK, Cohen EE (2015) Targeting the PI3K\/AKT\/mTOR pathway in squamous cell carcinoma of the head and neck. Oral Oncol 51:291\u2013298. doi:\n                    10.1016\/j.oraloncology.2014.11.012","journal-title":"Oral Oncol"},{"key":"3152_CR58","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2013.407","volume":"4","author":"L Chang","year":"2013","unstructured":"Chang L, Graham PH, Hao J, Ni J, Bucci J, Cozzi PJ, Kearsley JH, Li Y (2013) Acquisition of epithelial-mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K\/Akt\/mTOR pathway in prostate cancer radioresistance. Cell Death Dis 4:e875. doi:\n                    10.1038\/cddis.2013.407","journal-title":"Cell Death Dis"},{"key":"3152_CR59","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.3892\/ijo_00000751","volume":"37","author":"Y Nagata","year":"2010","unstructured":"Nagata Y, Takahashi A, Ohnishi K, Ota I, Ohnishi T, Tojo T, Taniguchi S (2010) Effect of rapamycin, an mTOR inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status. Int J Oncol 37:1001\u20131010","journal-title":"Int J Oncol"},{"key":"3152_CR60","doi-asserted-by":"publisher","first-page":"028002","DOI":"10.1117\/1.JBO.19.2.028002","volume":"19","author":"AC Pellicioli","year":"2014","unstructured":"Pellicioli AC, Martins MD, Dillenburg CS, Marques MM, Squarize CH, Castilho RM (2014) Laser phototherapy accelerates oral keratinocyte migration through the modulation of the mammalian target of rapamycin signaling pathway. J Biomed Opt 19:028002. doi:\n                    10.1117\/1.jbo.19.2.028002","journal-title":"J Biomed Opt"},{"key":"3152_CR61","doi-asserted-by":"publisher","unstructured":"Sperandio FF, Giudice FS, Correa L, Pinto DS Jr, Hamblin MR, de Sousa SC (2013) Low-level laser therapy can produce increased aggressiveness of dysplastic and oral cancer cell lines by modulation of Akt\/mTOR signaling pathway. J.Biophotonics. doi:\n                    10.1002\/jbio.201300015","DOI":"10.1002\/jbio.201300015"},{"key":"3152_CR62","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.bbcan.2006.06.004","volume":"1775","author":"K Pardali","year":"2007","unstructured":"Pardali K, Moustakas A (2007) Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer. Biochim Biophys Acta 1775:21\u201362. doi:\n                    10.1016\/j.bbcan.2006.06.004","journal-title":"Biochim Biophys Acta"},{"key":"3152_CR63","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1038\/nrc1208","volume":"3","author":"PM Siegel","year":"2003","unstructured":"Siegel PM, Massague J (2003) Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer. Nat Rev Cancer 3:807\u2013821. doi:\n                    10.1038\/nrc1208","journal-title":"Nat Rev Cancer"},{"key":"3152_CR64","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1177\/154411130401500603","volume":"15","author":"SS Prime","year":"2004","unstructured":"Prime SS, Davies M, Pring M, Paterson IC (2004) The role of TGF-beta in epithelial malignancy and its relevance to the pathogenesis of oral cancer (part II). Crit Rev Oral Biol Med 15:337\u2013347","journal-title":"Crit Rev Oral Biol Med"},{"key":"3152_CR65","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/j.archoralbio.2014.03.017","volume":"59","author":"YS Hwang","year":"2014","unstructured":"Hwang YS, Park KK, Chung WY (2014) Stromal transforming growth factor-beta 1 is crucial for reinforcing the invasive potential of low invasive cancer. Arch Oral Biol 59:687\u2013694. doi:\n                    10.1016\/j.archoralbio.2014.03.017","journal-title":"Arch Oral Biol"},{"key":"3152_CR66","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1007\/s10103-011-0985-z","volume":"26","author":"Y Dang","year":"2011","unstructured":"Dang Y, Liu B, Liu L, Ye X, Bi X, Zhang Y, Gu J (2011) The 800-nm diode laser irradiation induces skin Collagen synthesis by stimulating TGF-beta\/smad signaling pathway. Lasers Med Sci 26:837\u2013843. doi:\n                    10.1007\/s10103-011-0985-z","journal-title":"Lasers Med Sci"},{"key":"3152_CR67","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1007\/s00784-012-0756-7","volume":"17","author":"YK Chen","year":"2013","unstructured":"Chen YK, Huang AH, Cheng PH, Yang SH, Lin LM (2013) Overexpression of smad proteins, especially Smad7, in oral epithelial dysplasias. Clin Oral Investig 17:921\u2013932. doi:\n                    10.1007\/s00784-012-0756-7","journal-title":"Clin Oral Investig"},{"key":"3152_CR68","doi-asserted-by":"publisher","first-page":"3279","DOI":"10.1038\/sj.onc.1210421","volume":"26","author":"AS Dhillon","year":"2007","unstructured":"Dhillon AS, Hagan S, Rath O, Kolch W (2007) MAP kinase signalling pathways in cancer. Oncogene 26:3279\u20133290. doi:\n                    10.1038\/sj.onc.1210421","journal-title":"Oncogene"},{"key":"3152_CR69","first-page":"2382","volume":"7","author":"X Cui","year":"2014","unstructured":"Cui X, Li S, Li T, Pang X, Zhang S, Jin J, Hu J, Liu C, Yang L, Peng H, Jiang J, Liang W, Suo J, Li F, Chen Y (2014) Significance of elevated ERK expression and its positive correlation with EGFR in Kazakh patients with esophageal squamous cell carcinoma. Int J Clin Exp Pathol 7:2382\u20132391","journal-title":"Int J Clin Exp Pathol"},{"key":"3152_CR70","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1016\/j.cellsig.2012.01.013","volume":"24","author":"J Feng","year":"2012","unstructured":"Feng J, Zhang Y, Xing D (2012) Low-power laser irradiation (LPLI) promotes VEGF expression and vascular endothelial cell proliferation through the activation of ERK\/Sp1 pathway. Cell Signal 24:1116\u20131125. doi:\n                    10.1016\/j.cellsig.2012.01.013","journal-title":"Cell Signal"},{"key":"3152_CR71","doi-asserted-by":"publisher","first-page":"269","DOI":"10.5978\/islsm.12-OR-15","volume":"21","author":"Y Kawano","year":"2012","unstructured":"Kawano Y, Utsunomiya-Kai Y, Kai K, Miyakawa I, Ohshiro T, Narahara H (2012) The production of VEGF involving MAP kinase activation by low level laser therapy in human granulosa cells. Laser Ther 21:269\u2013274. doi:\n                    10.5978\/islsm.12-OR-15","journal-title":"Laser Ther"},{"key":"3152_CR72","doi-asserted-by":"publisher","unstructured":"Gupta A, Keshri GK, Yadav A, Gola S, Chauhan S, Salhan AK, Bala Singh S (2014) Superpulsed (Ga-As, 904\u00a0nm) low-level laser therapy (LLLT) attenuates inflammatory response and enhances healing of burn wounds. J Biophotonics 9999. doi:\n                    10.1002\/jbio.201400058","DOI":"10.1002\/jbio.201400058"},{"key":"3152_CR73","doi-asserted-by":"publisher","first-page":"13542","DOI":"10.3390\/ijms140713542","volume":"14","author":"T Kushibiki","year":"2013","unstructured":"Kushibiki T, Hirasawa T, Okawa S, Ishihara M (2013) Regulation of miRNA expression by low-level laser therapy (LLLT) and photodynamic therapy (PDT). Int J Mol Sci 14:13542\u201313558. doi:\n                    10.3390\/ijms140713542","journal-title":"Int J Mol Sci"},{"key":"3152_CR74","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1038\/nature10661","volume":"481","author":"KJ Png","year":"2012","unstructured":"Png KJ, Halberg N, Yoshida M, Tavazoie SF (2012) A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells. Nature 481:190\u2013194. doi:\n                    10.1038\/nature10661","journal-title":"Nature"},{"key":"3152_CR75","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1186\/1742-2094-9-219","volume":"9","author":"S Song","year":"2012","unstructured":"Song S, Zhou F, Chen WR (2012) Low-level laser therapy regulates microglial function through Src-mediated signaling pathways: implications for neurodegenerative diseases. J.Neuroinflammation. 9:219. doi:\n                    10.1186\/1742-2094-9-219","journal-title":"J.Neuroinflammation."},{"key":"3152_CR76","doi-asserted-by":"crossref","unstructured":"Shabbir M, Ryten M, Thompson C, Mikhailidis D and Burnstock G (2008) Purinergic receptor-mediated effects of ATP in high-grade bladder cancer. BJU.Int. 101:106\u2013112. doi:10.1111\/j.1464-410X.2007.07286.x","DOI":"10.1111\/j.1464-410X.2007.07286.x"},{"key":"3152_CR77","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1002\/lsm.1900090112","volume":"9","author":"R Marchesini","year":"1989","unstructured":"Marchesini R, Dasdia T, Melloni E, Rocca E (1989) Effect of low-energy laser irradiation on colony formation capability in different human tumor cells in vitro. Lasers Surg.Med. 9:59\u201362","journal-title":"Lasers Surg.Med."},{"key":"3152_CR78","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1007\/s10103-003-0265-7","volume":"18","author":"M Kreisler","year":"2003","unstructured":"Kreisler M, Christoffers AB, Willershausen B, d'Hoedt B (2003) Low-level 809\u00a0nm GaAlAs laser irradiation increases the proliferation rate of human laryngeal carcinoma cells in vitro. Lasers Med.Sci. 18:100\u2013103. doi:\n                    10.1007\/s10103-003-0265-7","journal-title":"Lasers Med.Sci."},{"key":"3152_CR79","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1089\/pho.2005.23.586","volume":"23","author":"JL de Castro","year":"2005","unstructured":"de Castro JL, Pinheiro AL, Werneck CE, Soares CP (2005) The effect of laser therapy on the proliferation of oral KB carcinoma cells: an in vitro study. Photomed.Laser Surg. 23:586\u2013589. doi:\n                    10.1089\/pho.2005.23.586","journal-title":"Photomed.Laser Surg."},{"key":"3152_CR80","unstructured":"Schaffer M, Sroka R, Fuchs C, Schrader-Reichardt U, Schaffer PM, Busch M and Duhmke E (1997) Biomodulative effects induced by 805\u00a0nm laser light irradiation of normal and tumor cells. J.Photochem.Photobiol.B 40:253\u2013257."},{"key":"3152_CR81","doi-asserted-by":"publisher","unstructured":"Pinheiro AL, Carneiro NS, Vieira AL, Brugnera A Jr, Zanin FA, Barros RA, Silva PS (2002) Effects of low-level laser therapy on malignant cells: in vitro study. J.Clin.Laser Med.Surg. 20:23\u201326. doi:\n                    10.1089\/104454702753474977","DOI":"10.1089\/104454702753474977"},{"key":"3152_CR82","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1089\/pho.2005.23.300","volume":"23","author":"CE Werneck","year":"2005","unstructured":"Werneck CE, Pinheiro AL, Pacheco MT, Soares CP, de Castro JL (2005) Laser light is capable of inducing proliferation of carcinoma cells in culture: a spectroscopic in vitro study. Photomed.Laser Surg. 23:300\u2013303. doi:\n                    10.1089\/pho.2005.23.300","journal-title":"Photomed.Laser Surg."},{"key":"3152_CR83","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1089\/pho.2007.2055","volume":"25","author":"AC Renno","year":"2007","unstructured":"Renno AC, McDonnell PA, Parizotto NA, Laakso EL (2007) The effects of laser irradiation on osteoblast and osteosarcoma cell proliferation and differentiation in vitro. Photomed.Laser Surg. 25:275\u2013280. doi:\n                    10.1089\/pho.2007.2055","journal-title":"Photomed.Laser Surg."},{"key":"3152_CR84","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1089\/pho.2008.2445","volume":"28","author":"K Powell","year":"2010","unstructured":"Powell K, Low P, McDonnell PA, Laakso EL, Ralph SJ (2010) The effect of laser irradiation on proliferation of human breast carcinoma, melanoma, and immortalized mammary epithelial cells. Photomed.Laser Surg. 28:115\u2013123. doi:\n                    10.1089\/pho.2008.2445","journal-title":"Photomed.Laser Surg."},{"key":"3152_CR85","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1034\/j.1600-0544.2001.040102.x","volume":"4","author":"AR Coombe","year":"2001","unstructured":"Coombe AR, Ho CT, Darendeliler MA, Hunter N, Philips JR, Chapple CC, Yum LW (2001) The effects of low level laser irradiation on osteoblastic cells. Clin.Orthod.Res. 4:3\u201314","journal-title":"Clin.Orthod.Res."},{"key":"3152_CR86","first-page":"185","volume":"115-116","author":"YH Liu","year":"2004","unstructured":"Liu YH, Cheng CC, Ho CC, Pei RJ, Lee KY, Yeh KT, Chan Y, Lai YS (2004) Effects of diode 808\u00a0nm GaAlAs low-power laser irradiation on inhibition of the proliferation of human hepatoma cells in vitro and their possible mechanism. Res Commun Mol Pathol Pharmacol 115-116:185\u2013201","journal-title":"Res Commun Mol Pathol Pharmacol"},{"key":"3152_CR87","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1002\/(SICI)1096-9101(1999)25:3<263::AID-LSM11>3.0.CO;2-T","volume":"25","author":"R Sroka","year":"1999","unstructured":"Sroka R, Schaffer M, Fuchs C, Pongratz T, Schrader-Reichard U, Busch M, Schaffer PM, Duhmke E, Baumgartner R (1999) Effects on the mitosis of normal and tumor cells induced by light treatment of different wavelengths. Lasers Surg.Med. 25:263\u2013271. doi:\n                    10.1002\/(SICI)1096-9101(1999)25:3<263::AID-LSM11>3.0.CO;2-T","journal-title":"Lasers Surg.Med."},{"key":"3152_CR88","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1007\/s10103-011-0924-z","volume":"27","author":"H Murayama","year":"2012","unstructured":"Murayama H, Sadakane K, Yamanoha B, Kogure S (2012) Low-power 808-nm laser irradiation inhibits cell proliferation of a human-derived glioblastoma cell line in vitro. Lasers Med Sci 27:87\u201393. doi:\n                    10.1007\/s10103-011-0924-z","journal-title":"Lasers Med Sci"},{"key":"3152_CR89","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1007\/s10103-011-1040-9","volume":"27","author":"FA Al-Watban","year":"2012","unstructured":"Al-Watban FA, Andres BL (2012) Laser biomodulation of normal and neoplastic cells. Lasers Med Sci 27:1039\u20131043. doi:\n                    10.1007\/s10103-011-1040-9","journal-title":"Lasers Med Sci"},{"key":"3152_CR90","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1186\/scrt340","volume":"4","author":"AM Crous","year":"2013","unstructured":"Crous AM, Abrahamse H (2013) Lung cancer stem cells and low-intensity laser irradiation: a potential future therapy? Stem Cell Res Ther 4:129. doi:\n                    10.1186\/scrt340","journal-title":"Stem Cell Res Ther"},{"key":"3152_CR91","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1007\/s00520-011-1113-0","volume":"20","author":"VH Schartinger","year":"2012","unstructured":"Schartinger VH, Galvan O, Riechelmann H, Dudas J (2012) Differential responses of fibroblasts, non-neoplastic epithelial cells, and oral carcinoma cells to low-level laser therapy. Support. Care Cancer 20:523\u2013529. doi:\n                    10.1007\/s00520-011-1113-0","journal-title":"Support. Care Cancer"},{"key":"3152_CR92","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.pdpdt.2014.10.009","volume":"12","author":"SR Tsai","year":"2015","unstructured":"Tsai SR, Yin R, Huang YY, Sheu BC, Lee SC, Hamblin MR (2015) Low-level light therapy potentiates NPe6-mediated photodynamic therapy in a human osteosarcoma cell line via increased ATP. Photodiagn Photodyn Ther 12:123\u2013130. doi:\n                    10.1016\/j.pdpdt.2014.10.009","journal-title":"Photodiagn Photodyn Ther"},{"key":"3152_CR93","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-015-3051-8","author":"A Barasch","year":"2015","unstructured":"Barasch A, Raber-Durlacher J, Epstein JB, Carroll J (2015) Effects of pre-radiation exposure to LLLT of normal and malignant cells. Support Care Cancer. doi:\n                    10.1007\/s00520-015-3051-8","journal-title":"Support Care Cancer"},{"key":"3152_CR94","first-page":"621","volume":"9","author":"E Mester","year":"1968","unstructured":"Mester E, Szende B, Gartner P (1968) The effect of laser beams on the growth of hair in mice. RadiobiolRadiother(Berl) 9:621\u2013626","journal-title":"RadiobiolRadiother(Berl)"},{"key":"3152_CR95","doi-asserted-by":"publisher","unstructured":"de CMJ, Pinheiro AN, de Oliveira SC, Aciole GT, Sousa JA, Canguss MC and Dos Santos JN (2011) Influence of laser phototherapy (lambda 660 nm) on the outcome of oral chemical carcinogenesis on the hamster cheek pouch model: histological study. Photomed.Laser Surg. 29:741\u2013745. doi:\n                    10.1089\/pho.2010.2896","DOI":"10.1089\/pho.2010.2896"},{"key":"3152_CR96","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1186\/1471-2407-9-404","volume":"9","author":"L Frigo","year":"2009","unstructured":"Frigo L, Luppi JS, Favero GM, Maria DA, Penna SC, Bjordal JM, Bensadoun RJ, Lopes-Martins RA (2009) The effect of low-level laser irradiation (In-Ga-Al-AsP\u2014660\u00a0nm) on melanoma in vitro and in vivo. BMC.Cancer 9:404. doi:\n                    10.1186\/1471-2407-9-404","journal-title":"BMC.Cancer"},{"key":"3152_CR97","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1089\/pho.2011.3186","volume":"30","author":"M Myakishev-Rempel","year":"2012","unstructured":"Myakishev-Rempel M, Stadler I, Brondon P, Axe DR, Friedman M, Nardia FB, Lanzafame R (2012) A preliminary study of the safety of red light phototherapy of tissues harboring cancer. Photomed.Laser Surg. 30:551\u2013558. doi:\n                    10.1089\/pho.2011.3186","journal-title":"Photomed.Laser Surg."},{"key":"3152_CR98","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/S1011-1344(99)00155-4","volume":"54","author":"M Schaffer","year":"2000","unstructured":"Schaffer M, Bonel H, Sroka R, Schaffer PM, Busch M, Reiser M, Duhmke E (2000) Effects of 780\u00a0nm diode laser irradiation on blood microcirculation: preliminary findings on time-dependent T1-weighted contrast-enhanced magnetic resonance imaging (MRI). J Photochem Photobiol B 54:55\u201360","journal-title":"J Photochem Photobiol B"},{"key":"3152_CR99","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.radonc.2013.08.010","volume":"109","author":"HS Antunes","year":"2013","unstructured":"Antunes HS, Herchenhorn D, Small IA, Araujo CM, Viegas CM, Cabral E, Rampini MP, Rodrigues PC, Silva TG, Ferreira EM, Dias FL, Ferreira CG (2013) Phase III trial of low-level laser therapy to prevent oral mucositis in head and neck cancer patients treated with concurrent chemoradiation. Radiother Oncol 109:297\u2013302. doi:\n                    10.1016\/j.radonc.2013.08.010","journal-title":"Radiother Oncol"},{"key":"3152_CR100","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1089\/pho.2012.3355","volume":"31","author":"TC Liu","year":"2013","unstructured":"Liu TC, Zhang J, Li XE (2013) The balance between normal and tumor tissues in phototherapy of tissues harboring cancer. Photomed Laser Surg 31:93\u201394. doi:\n                    10.1089\/pho.2012.3355","journal-title":"Photomed Laser Surg"},{"key":"3152_CR101","doi-asserted-by":"publisher","unstructured":"Sonis ST, Hashemi S, Epstein JB, Nair RG, Raber-Durlacher JE (2016) Could the biological robustness of low level laser therapy (Photobiomodulation) impact its use in the management of mucositis in head and neck cancer patients. Oral Oncol.54:7\u201314. doi::\n                    10.1016\/j.oraloncology.2016.01.005","DOI":"10.1016\/j.oraloncology.2016.01.005"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-016-3152-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00520-016-3152-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-016-3152-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-016-3152-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T11:20:54Z","timestamp":1589628054000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00520-016-3152-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,16]]},"references-count":101,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["3152"],"URL":"https:\/\/doi.org\/10.1007\/s00520-016-3152-z","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,16]]},"assertion":[{"value":"2 August 2015","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 March 2016","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 March 2016","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Judith E. Raber-Durlacher, Raj G. Nair, Joel B. Epstein, Ron van der Brink, Josep Arnabat Dominguez, and Rene-Jean Bensadoun have received travel expenses and hotel accommodation from THOR Photomedicine Ltd. UK. Raj Nair has received an honorarium from THOR, UK. Michael R Hamblin was supported by US NIH grant R01AI050875. All the other authors declare that they have no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}