{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T05:02:37Z","timestamp":1774674157303,"version":"3.50.1"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T00:00:00Z","timestamp":1617062400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T00:00:00Z","timestamp":1617062400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100007602","name":"Programme Grants for Applied Research","doi-asserted-by":"publisher","award":["RP-DG-1212-10014"],"award-info":[{"award-number":["RP-DG-1212-10014"]}],"id":[{"id":"10.13039\/501100007602","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>The aim of this study was to identify the most appropriate measure of quality of life (QoL) for patients living with and beyond cancer.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>One hundred eighty-two people attending cancer clinics in Central London at various stages post-treatment, completed a series of QoL measures: FACT-G, EORTC QLQ-C30 , IOCv2 (positive and negative subscales) and WEMWBS, a wellbeing measure. These measures were chosen as the commonest measures used in previous research. Correlation tests were used to assess the association between scales. Participants were also asked about pertinence and ease of completion.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>There was a significant positive correlation between the four domain scores of the two health-related QoL measures (.32 \u2264 <jats:italic>r<\/jats:italic> \u2264 .72, <jats:italic>P<\/jats:italic> &lt; .001), and a significant large negative correlation between these and the negative IOCv2 subscale scores (\u2212 .39 \u2264 <jats:italic>r<\/jats:italic> \u2264 \u2212 .63, <jats:italic>P<\/jats:italic> &lt; .001). There was a significant moderate positive correlation between positive IOCv2 subscale and WEMWBS scores (<jats:italic>r<\/jats:italic> = .35, <jats:italic>P<\/jats:italic> &lt; .001). However, neither the FACT-G nor the EORTC showed any significant correlation with the positive IOCv2 subscale. Participants rated all measures similarly with regards to pertinence and ease of use.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>There was little to choose between FACT-G, EORTC, and the negative IOC scales, any of which may be used to measure QoL. However, the two IOCv2 subscales capture unique aspects of QoL compared to the other measures. The IOCv2 can be used to identify those cancer survivors who would benefit from interventions to improve their QoL and to target specific needs thereby providing more holistic and personalised care beyond cancer treatment.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00520-021-06105-z","type":"journal-article","created":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T05:02:40Z","timestamp":1617080560000},"page":"6031-6038","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Measuring quality of life in people living with and beyond cancer in the UK"],"prefix":"10.1007","volume":"29","author":[{"given":"Elisavet","family":"Moschopoulou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Deane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morvwen","family":"Duncan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharif A.","family":"Ismail","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Moriarty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shah-Jalal","family":"Sarker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"White","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ania","family":"Korszun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the SURECAN Development Grant investigators","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamaldeep","family":"Bhui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liam","family":"Bourke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trudie","family":"Chalder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Eldridge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Gribben","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"McCrone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrienne","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damien","family":"Ridge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Roylance","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steph","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Thaha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,3,30]]},"reference":[{"key":"6105_CR1","unstructured":"Macmillan Cancer Support (2019) Statistics fact sheet. https:\/\/www.macmillan.org.uk\/_images\/cancer-statistics-factsheet_tcm9-260514.pdf. Accessed 16 June 2020"},{"issue":"9974","key":"6105_CR2","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.1016\/S0140-6736(14)61396-9","volume":"385","author":"M Quaresma","year":"2015","unstructured":"Quaresma M, Coleman MP, Rachet B (2015) 40-year trends in an index of survival for all cancers combined and survival adjusted for age and sex for each cancer in England and Wales, 1971\u20132011: a population-based study. Lancet 385(9974):1206\u20131218. https:\/\/doi.org\/10.1016\/S0140-6736(14)61396-9","journal-title":"Lancet"},{"issue":"9","key":"6105_CR3","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1038\/bjc.2016.304","volume":"115","author":"CR Smittenaar","year":"2016","unstructured":"Smittenaar CR, Petersen KA, Stewart K, Moitt N (2016) Cancer incidence and mortality projections in the UK until 2035. Br J Cancer 115(9):1147\u20131155. https:\/\/doi.org\/10.1038\/bjc.2016.304","journal-title":"Br J Cancer"},{"issue":"7","key":"6105_CR4","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1038\/bjc.2012.366","volume":"107","author":"J Maddams","year":"2012","unstructured":"Maddams J, Utley M, M\u00f8ller H (2012) Projections of cancer prevalence in the United Kingdom, 2010\u20132040. Br J Cancer 107(7):1195\u20131202. https:\/\/doi.org\/10.1038\/bjc.2012.366","journal-title":"Br J Cancer"},{"issue":"2","key":"6105_CR5","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1634\/theoncologist.7-2-120","volume":"7","author":"A Bottomley","year":"2002","unstructured":"Bottomley A (2002) The cancer patient and quality of life. Oncologist 7(2):120\u2013125","journal-title":"Oncologist"},{"issue":"2","key":"6105_CR6","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1177\/1758834010395342","volume":"3","author":"D Osoba","year":"2011","unstructured":"Osoba D (2011) Health-related quality of life and cancer clinical trials. Ther Adv Med Oncol 3(2):57\u201371. https:\/\/doi.org\/10.1177\/1758834010395342","journal-title":"Ther Adv Med Oncol"},{"issue":"6","key":"6105_CR7","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1111\/bjh.12698","volume":"164","author":"A Korszun","year":"2014","unstructured":"Korszun A, Sarker SJ, Chowdhury K, Clark C, Greaves P, Johnson R, Kingston J, Levitt G, Matthews J, White P, Lister A, Gribben J (2014) Psychosocial factors associated with impact of cancer in longterm haematological cancer survivors. Br J Haematol 164(6):790\u2013803. https:\/\/doi.org\/10.1111\/bjh.12698","journal-title":"Br J Haematol"},{"key":"6105_CR8","unstructured":"Department of Health (2012) Quality of life of cancer survivors in England. https:\/\/assets.publishing.service.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/267042\/9284-TSO-2900701-PROMS-1.pdf. Accessed 16 June 2020"},{"issue":"6","key":"6105_CR9","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1007\/s11764-019-00805-6","volume":"13","author":"SC Sodergren","year":"2019","unstructured":"Sodergren SC, Wheelwright SJ, Permyakova NV, Patel M, Calman L, Smith PWF, Din A, Richardson A, Fenlon D, Winter J, Corner J, Foster C (2019) Supportive care needs of patients following treatment for colorectal cancer: risk factors for unmet needs and the association between unmet needs and health related quality of life-results from the ColoREctal Wellbeing (CREW) study. Journal of Cancer Survivorship: Research and Practice 13(6):899\u2013909. https:\/\/doi.org\/10.1007\/s11764-019-00805-6","journal-title":"Journal of Cancer Survivorship: Research and Practice"},{"issue":"4","key":"6105_CR10","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1007\/s11764-013-0299-1","volume":"7","author":"PA Vissers","year":"2013","unstructured":"Vissers PA, Thong MS, Pouwer F, Zanders MM, Coebergh JW, van de Poll-Franse LV (2013) The impact of comorbidity on health-related quality of life among cancer survivors: analyses of data from the PROFILES registry. J Cancer Surviv 7(4):602\u2013613. https:\/\/doi.org\/10.1007\/s11764-013-0299-1","journal-title":"J Cancer Surviv"},{"issue":"6","key":"6105_CR11","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1002\/pon.3719","volume":"24","author":"LK Shand","year":"2015","unstructured":"Shand LK, Cowlishaw S, Brooker JE, Burney S, Ricciardelli LA (2015) Correlates of post-traumatic stress symptoms and growth in cancer patients: a systematic review and meta-analysis. Psycho-oncology 24(6):624\u2013634. https:\/\/doi.org\/10.1002\/pon.3719","journal-title":"Psycho-oncology"},{"issue":"5","key":"6105_CR12","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1002\/pon.963","volume":"15","author":"BJ Zebrack","year":"2006","unstructured":"Zebrack BJ, Ganz PA, Bernaards CA, Petersen L, Abraham L (2006) Assessing the impact of cancer: development of a new instrument for long-term survivors. Psychooncology 15(5):407\u2013421. https:\/\/doi.org\/10.1002\/pon.963","journal-title":"Psychooncology"},{"issue":"3","key":"6105_CR13","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1080\/07347332.2015.1020978","volume":"33","author":"AL Bryant","year":"2015","unstructured":"Bryant AL, Smith SK, Zimmer C, Crandell J, Jenerette CM, Bailey DE Jr, Zimmerman S, Mayer DK (2015) An exploratory path model of the relationships between positive and negative adaptation to cancer on quality of life among non-Hodgkin lymphoma survivors. J Psychosoc Oncol 33(3):310\u2013331. https:\/\/doi.org\/10.1080\/07347332.2015.1020978","journal-title":"J Psychosoc Oncol"},{"issue":"6","key":"6105_CR14","doi-asserted-by":"publisher","first-page":"1258","DOI":"10.1002\/pon.3131","volume":"22","author":"S Oerlemans","year":"2013","unstructured":"Oerlemans S, Smith SK, Crespi CM, Zimmerman S, van de Poll-Franse LV, Ganz PA (2013) Assessing the impact of cancer among Dutch non-Hodgkin lymphoma survivors compared with their American counterparts: a cross-national study. Psychooncology 22(6):1258\u20131265. https:\/\/doi.org\/10.1002\/pon.3131","journal-title":"Psychooncology"},{"issue":"1","key":"6105_CR15","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/s11764-009-0106-1","volume":"4","author":"CM Crespi","year":"2010","unstructured":"Crespi CM, Smith SK, Petersen L, Zimmerman S, Ganz PA (2010) Measuring the impact of cancer: a comparison of non-Hodgkin lymphoma and breast cancer survivors. Journal of Cancer Survivorship : Research and Practice 4(1):45\u201358. https:\/\/doi.org\/10.1007\/s11764-009-0106-1","journal-title":"Journal of Cancer Survivorship : Research and Practice"},{"issue":"8","key":"6105_CR16","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.1007\/s11136-011-0053-y","volume":"21","author":"AA Dahl","year":"2012","unstructured":"Dahl AA, Gudbergsson SB, Dorum A, Fossa SD, Liavaag AH, Sorebo O (2012) \"The impact of cancer scale\" version 1: psychometric testing of the Norwegian translation in a heterogeneous sample of cancer survivors. Qual Life Res 21(8):1459\u20131470. https:\/\/doi.org\/10.1007\/s11136-011-0053-y","journal-title":"Qual Life Res"},{"issue":"5","key":"6105_CR17","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1093\/jnci\/85.5.365","volume":"85","author":"NK Aaronson","year":"1993","unstructured":"Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, Filiberti A, Flechtner H, Fleishman SB, de Haes JC et al (1993) The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 85(5):365\u2013376","journal-title":"J Natl Cancer Inst"},{"issue":"3","key":"6105_CR18","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1200\/JCO.1993.11.3.570","volume":"11","author":"DF Cella","year":"1993","unstructured":"Cella DF, Tulsky DS, Gray G, Sarafian B, Linn E, Bonomi A, Silberman M, Yellen SB, Winicour P, Brannon J et al (1993) The functional assessment of Cancer therapy scale: development and validation of the general measure. J Clin Oncol 11(3):570\u2013579","journal-title":"J Clin Oncol"},{"issue":"10","key":"6105_CR19","doi-asserted-by":"publisher","first-page":"2179","DOI":"10.1093\/annonc\/mdq721","volume":"22","author":"T Luckett","year":"2011","unstructured":"Luckett T, King MT, Butow PN, Oguchi M, Rankin N, Price MA, Hackl NA, Heading G (2011) Choosing between the EORTC QLQ-C30 and FACT-G for measuring health-related quality of life in cancer clinical research: issues, evidence and recommendations. Annals of Oncology : Official Journal of the European Society for Medical Oncology \/ ESMO 22(10):2179\u20132190. https:\/\/doi.org\/10.1093\/annonc\/mdq721","journal-title":"Annals of Oncology : Official Journal of the European Society for Medical Oncology \/ ESMO"},{"issue":"1","key":"6105_CR20","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.ejcsup.2014.03.005","volume":"12","author":"NK Aaronson","year":"2014","unstructured":"Aaronson NK, Mattioli V, Minton O, Weis J, Johansen C, Dalton SO, Verdonck-de Leeuw IM, Stein KD, Alfano CM, Mehnert A, de Boer A, van de Poll-Franse LV (2014) Beyond treatment \u2013 psychosocial and behavioural issues in cancer survivorship research and practice. Eur J Cancer Suppl 12(1):54\u201364","journal-title":"Eur J Cancer Suppl"},{"issue":"3","key":"6105_CR21","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1007\/s00520-016-3454-1","volume":"25","author":"S-J Sarker","year":"2017","unstructured":"Sarker S-J, Smith SK, Chowdhury K, Ganz PA, Zimmerman S, Gribben J, Korszun A (2017) Comparison of the impact of cancer between British and US long-term non-Hodgkin lymphoma survivors. Support Care Cancer 25(3):739\u2013748","journal-title":"Support Care Cancer"},{"issue":"4","key":"6105_CR22","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1136\/qhc.11.4.392","volume":"11","author":"K Walshe","year":"2002","unstructured":"Walshe K (2002) Principles for best practice in clinical audit. Qual Saf Health Care 11(4):392\u2013392. https:\/\/doi.org\/10.1136\/qhc.11.4.392","journal-title":"Qual Saf Health Care"},{"issue":"4","key":"6105_CR23","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/S0895-4356(96)00428-3","volume":"50","author":"M Groenvold","year":"1997","unstructured":"Groenvold M, Klee MC, Sprangers MAG, Aaronson NK (1997) Validation of the EORTC QLQ-C30 quality of life questionnaire through combined qualitative and quantitative assessment of patient-observer agreement. J Clin Epidemiol 50(4):441\u2013450","journal-title":"J Clin Epidemiol"},{"issue":"1","key":"6105_CR24","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1186\/1477-7525-5-63","volume":"5","author":"R Tennant","year":"2007","unstructured":"Tennant R, Hiller L, Fishwick R, Platt S, Joseph S, Weich S, Parkinson J, Secker J, Stewart-Brown S (2007) The Warwick-Edinburgh Mental Well-being Scale (WEMWBS): development and UK validation. Health Qual Life Outcomes 5(1):63","journal-title":"Health Qual Life Outcomes"},{"issue":"21","key":"6105_CR25","doi-asserted-by":"publisher","first-page":"1530","DOI":"10.1093\/jnci\/djn340","volume":"100","author":"CM Crespi","year":"2008","unstructured":"Crespi CM, Ganz PA, Petersen L, Castillo A, Caan B (2008) Refinement and psychometric evaluation of the impact of cancer scale. JNCI: Journal of the National Cancer Institute 100(21):1530\u20131541","journal-title":"JNCI: Journal of the National Cancer Institute"},{"key":"6105_CR26","unstructured":"Stanton AL, Bower JE, Low CA (2006) Posttraumatic growth after Cancer. In: Calhoun LG, Tedeschi RG (eds) Handbook of posttraumatic growth: research & practice, p. 138\u2013175. Lawrence Erlbaum Associates Publishers"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-021-06105-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-021-06105-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-021-06105-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T09:20:01Z","timestamp":1630488001000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-021-06105-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,30]]},"references-count":26,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["6105"],"URL":"https:\/\/doi.org\/10.1007\/s00520-021-06105-z","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,30]]},"assertion":[{"value":"2 September 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 February 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was an audit; \u201cAudit of well-being\/quality of life measures in cancer survivors\u201d ID: 5711 (2015) Barts Health NHS Trust. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"N\/A","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"PW does consultancy work for a re-insurance company and is a member of the Independent Medical Experts\u2019 Group, which advises the UK Ministry of Defense regarding its Armed Forces Compensation Scheme. The other authors declare that they have no conflicts of interest.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}