{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:24:50Z","timestamp":1786980290856,"version":"build-2736575974"},"reference-count":66,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T00:00:00Z","timestamp":1618272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T00:00:00Z","timestamp":1618272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1007\/s00520-021-06188-8","type":"journal-article","created":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T02:02:56Z","timestamp":1618279376000},"page":"6943-6956","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["The scalp cooling therapy for hair loss in breast cancer patients undergoing chemotherapy: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"29","author":[{"given":"Shurui","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aomei","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanmin","family":"Qiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zihan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangyuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,13]]},"reference":[{"key":"6188_CR1","doi-asserted-by":"publisher","first-page":"394","DOI":"10.3322\/caac.21492","volume":"68","author":"B Freddie","year":"2018","unstructured":"Freddie B, Jacques F, Isabelle S et al (2018) Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 68:394\u2013424","journal-title":"CA Cancer J Clin"},{"key":"6188_CR2","first-page":"543","volume":"12","author":"J Hesketh Paul","year":"2004","unstructured":"Hesketh Paul J (2004) Batchelor Diane, Golant Mitch et al. Chemotherapy-induced alopecia: psychosocial impact and therapeutic approaches. Support Care Cancer 12:543\u2013549","journal-title":"Support Care Cancer"},{"key":"6188_CR3","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1111\/j.1529-8019.2011.01430.x","volume":"24","author":"E Yeager Caroline","year":"2011","unstructured":"Yeager Caroline E, Olsen Elise A (2011) Treatment of chemotherapy-induced alopecia. Dermatol Ther 24:432\u2013442","journal-title":"Dermatol Ther"},{"key":"6188_CR4","doi-asserted-by":"publisher","first-page":"1640","DOI":"10.1038\/bjc.1997.610","volume":"76","author":"G Macquart-Moulin","year":"1997","unstructured":"Macquart-Moulin G, Viens P, Bouscary ML, Genre D, Resbeut M, Gravis G, Camerlo J, Maraninchi D, Moatti JP (1997) Discordance between physicians\u2019 estimations and breast cancer patients\u2019 self-assessment of side-effects of chemotherapy: an issue for quality of care. Br J Cancer 76:1640\u20131645","journal-title":"Br J Cancer"},{"key":"6188_CR5","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1056\/NEJM197912273012605","volume":"301","author":"JC Dean","year":"1979","unstructured":"Dean JC, Salmon SE, Griffith KS (1979) Prevention of doxorubicin-induced hair loss with scalp hypothermia. N Engl J Med 301:1427\u20131429","journal-title":"N Engl J Med"},{"key":"6188_CR6","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1046\/j.1365-2354.2001.00272.x","volume":"10","author":"D Batchelor","year":"2001","unstructured":"Batchelor D (2001) Hair and cancer chemotherapy: consequences and nursing care--a literature study. Eur J Cancer Care (Engl) 10:147\u2013163","journal-title":"Eur J Cancer Care (Engl)"},{"key":"6188_CR7","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1002\/pon.3531","volume":"23","author":"CE Kyung","year":"2014","unstructured":"Kyung CE, Im-Ryung K, Oliver C et al (2014) Impact of chemotherapy-induced alopecia distress on body image, psychosocial well-being, and depression in breast cancer patients. Psychooncology 23:1103\u20131110","journal-title":"Psychooncology"},{"key":"6188_CR8","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.breast.2018.07.006","volume":"41","author":"C Arlene","year":"2018","unstructured":"Arlene C, Astrid B, Sally P et al (2018) Efficacy of scalp cooling in reducing alopecia in early breast cancer patients receiving contemporary chemotherapy regimens. Breast 41:127\u2013132","journal-title":"Breast"},{"key":"6188_CR9","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1002\/pon.1245","volume":"17","author":"L Julie","year":"2008","unstructured":"Julie L, Elizabeth M, Louise P (2008) Chemotherapy-induced alopecia and effects on quality of life among women with breast cancer: a literature review. Psychooncology 17:317\u2013328","journal-title":"Psychooncology"},{"key":"6188_CR10","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1007\/s10549-009-0342-0","volume":"118","author":"L Julie","year":"2009","unstructured":"Julie L, Carl A, Louise P et al (2009) Incidence of scalp metastases in breast cancer: a retrospective cohort study in women who were offered scalp cooling. Breast Cancer Res Treat 118:547\u2013552","journal-title":"Breast Cancer Res Treat"},{"key":"6188_CR11","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.clbc.2017.07.012","volume":"18","author":"S Rugo Hope","year":"2018","unstructured":"Rugo Hope S, Jeffrey V (2018) Scalp hypothermia for preventing alopecia during chemotherapy. A systematic review and meta-analysis of randomized controlled trials. Clin Breast Cancer 18:19\u201328","journal-title":"Clin Breast Cancer"},{"key":"6188_CR12","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1111\/jdv.14612","volume":"32","author":"VV Shah","year":"2018","unstructured":"Shah VV, Wikramanayake TC, DelCanto GM, van den Hurk C, Wu S, Lacouture ME, Jimenez JJ (2018) Scalp hypothermia as a preventative measure for chemotherapy-induced alopecia: a review of controlled clinical trials. J Eur Acad Dermatol Venereol 32:720\u2013734","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"6188_CR13","doi-asserted-by":"publisher","first-page":"E442","DOI":"10.1002\/ijc.29115","volume":"136","author":"S Hyoseung","year":"2015","unstructured":"Hyoseung S, Jin JS, Do Hun K et al (2015) Efficacy of interventions for prevention of chemotherapy-induced alopecia: a systematic review and meta-analysis. Int J Cancer 136:E442\u2013E454","journal-title":"Int J Cancer"},{"key":"6188_CR14","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1007\/s00520-002-0375-y","volume":"10","author":"P Christel","year":"2002","unstructured":"Christel P, Katrin E, Jacques C et al (2002) Efficacy and tolerance of a scalp-cooling system for prevention of hair loss and the experience of breast cancer patients treated by adjuvant chemotherapy. Support Care Cancer 10:529\u2013537","journal-title":"Support Care Cancer"},{"key":"6188_CR15","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.ejon.2003.10.006","volume":"8","author":"S Massey Carolyn","year":"2004","unstructured":"Massey Carolyn S (2004) A multicentre study to determine the efficacy and patient acceptability of the Paxman Scalp Cooler to prevent hair loss in patients receiving chemotherapy. Eur J Oncol Nurs 8:121\u2013130","journal-title":"Eur J Oncol Nurs"},{"key":"6188_CR16","doi-asserted-by":"publisher","first-page":"497","DOI":"10.3109\/0284186X.2012.658966","volume":"51","author":"CJ van den Hurk","year":"2012","unstructured":"van den Hurk CJ, Mijke P, van de Poll-Franse Lonneke V et al (2012) Scalp cooling for hair preservation and associated characteristics in 1411 chemotherapy patients - results of the Dutch Scalp Cooling Registry. Acta Oncol 51:497\u2013504","journal-title":"Acta Oncol"},{"key":"6188_CR17","doi-asserted-by":"publisher","first-page":"1919","DOI":"10.1007\/s00520-018-4432-6","volume":"27","author":"MC Komen Manon","year":"2019","unstructured":"Komen Manon MC, van den Hurk CJG, Nortier Johan WR et al (2019) Prolonging the duration of post-infusion scalp cooling in the prevention of anthracycline-induced alopecia: a randomised trial in patients with breast cancer treated with adjuvant chemotherapy. Support Care Cancer 27:1919\u20131925","journal-title":"Support Care Cancer"},{"key":"6188_CR18","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1001\/jama.2016.21038","volume":"317","author":"S Rugo Hope","year":"2017","unstructured":"Rugo Hope S, Paula K, Anitra MS et al (2017) Association between use of a scalp cooling device and alopecia after chemotherapy for breast cancer. JAMA 317:606\u2013614","journal-title":"JAMA"},{"key":"6188_CR19","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1001\/jama.2016.20939","volume":"317","author":"N Julie","year":"2017","unstructured":"Julie N, Wang T, Cynthia O et al (2017) Effect of a scalp cooling device on alopecia in women undergoing chemotherapy for breast cancer: the SCALP randomized clinical trial. JAMA 317:596\u2013605","journal-title":"JAMA"},{"key":"6188_CR20","doi-asserted-by":"crossref","unstructured":"C. MACDUFF, T. MACKENZIE, A. HUTCHEON, L. MELVILLE, H. ARCHIBALD, (2003) The effectiveness of scalp cooling in preventing alopecia for patients receiving epirubicin and docetaxel. European Journal of Cancer Care 12 (2):154-161","DOI":"10.1046\/j.1365-2354.2003.00382.x"},{"key":"6188_CR21","doi-asserted-by":"crossref","unstructured":"Marzieh K (2011) Sarvestani Raheleh Sabet, Khojasteh Habib Noorani et al. Efficacy of penguin cap as scalp cooling system for prevention of alopecia in patients undergoing chemotherapy. J Adv Nurs 67:2473\u20132477","DOI":"10.1111\/j.1365-2648.2011.05668.x"},{"key":"6188_CR22","doi-asserted-by":"crossref","unstructured":"Betticher Daniel C (2013) Delmore Geoffrey, Breitenstein Urs et al. Efficacy and tolerability of two scalp cooling systems for the prevention of alopecia associated with docetaxel treatment. Support Care Cancer 21:2565\u20132573","DOI":"10.1007\/s00520-013-1804-9"},{"key":"6188_CR23","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1054\/ejon.2000.0094","volume":"4","author":"HJ Peck","year":"2000","unstructured":"Peck HJ, Mitchell H, Stewart AL (2000) Evaluating the efficacy of scalp cooling using the Penguin cold cap system to reduce alopecia in patients undergoing chemotherapy for breast cancer. Eur J Oncol Nurs 4:246\u2013248","journal-title":"Eur J Oncol Nurs"},{"key":"6188_CR24","first-page":"913","volume":"71","author":"MH Robinson","year":"1987","unstructured":"Robinson MH, Jones AC, Durrant KD (1987) Effectiveness of scalp cooling in reducing alopecia caused by epirubicin treatment of advanced breast cancer. Cancer Treat Rep 71:913\u2013914","journal-title":"Cancer Treat Rep"},{"key":"6188_CR25","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1186\/2193-1801-3-500","volume":"3","author":"F Kay","year":"2014","unstructured":"Kay F, Carstensen Martin H (2014) Successful reduction of alopecia induced by anthracycline and taxane containing adjuvant chemotherapy in breast cancer\u2014clinical evaluation of sensor-controlled scalp cooling. Springerplus 3:500","journal-title":"Springerplus"},{"key":"6188_CR26","first-page":"170","volume":"11","author":"G Giaccone","year":"1988","unstructured":"Giaccone G, Di Giulio F, Morandini MP et al (1988) Scalp hypothermia in the prevention of doxorubicin-induced hair loss. Cancer Nurs 11:170\u2013173","journal-title":"Cancer Nurs"},{"key":"6188_CR27","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1046\/j.1365-2354.2003.00382.x","volume":"12","author":"C Macduff","year":"2003","unstructured":"Macduff C, Mackenzie T, Hutcheon A et al (2003) The effectiveness of scalp cooling in preventing alopecia for patients receiving epirubicin and docetaxel. Eur J Cancer Care (Engl) 12:154\u2013161","journal-title":"Eur J Cancer Care (Engl)"},{"key":"6188_CR28","unstructured":"Rostom A, Dube C, Cranney A, et al. Celiac disease. Rockville (MD): Agency for Healthcare Research and Quality (US); 2004Sep. (Evidence Reports\/Technology Assessments, No.104.) Appendix D. Quality Assessment Forms. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK35156."},{"key":"6188_CR29","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1007\/s10654-010-9491-z","volume":"25","author":"S Andreas","year":"2010","unstructured":"Andreas S (2010) Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol 25:603\u2013605","journal-title":"Eur J Epidemiol"},{"key":"6188_CR30","unstructured":"Cochrane handbook for systematic reviews of interventions version5.1.0[EB\/OL]. http:\/\/handbook.cochrane.org."},{"key":"6188_CR31","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","volume":"327","author":"PT Higgins Julian","year":"2003","unstructured":"Higgins Julian PT, Thompson Simon G, Deeks Jonathan J et al (2003) Measuring inconsistency in meta-analyses. BMJ 327:557\u2013560","journal-title":"BMJ"},{"key":"6188_CR32","doi-asserted-by":"publisher","first-page":"277","DOI":"10.4103\/apjon.apjon_4_19","volume":"6","author":"G Emilia","year":"2019","unstructured":"Emilia G, Giorgia R, Manuela B et al (2019) Scalp cooling in daily clinical practice for breast cancer patients undergoing curative chemotherapy: a multicenter interventional study. Asia Pac J Oncol Nurs 6:277\u2013282","journal-title":"Asia Pac J Oncol Nurs"},{"key":"6188_CR33","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/j.clbc.2015.01.003","volume":"15","author":"C Tessa","year":"2015","unstructured":"Tessa C, Devora I, Barbara F et al (2015) Efficacy of scalp cooling in preventing chemotherapy-induced alopecia in breast cancer patients receiving adjuvant docetaxel and cyclophosphamide chemotherapy. Clin Breast Cancer 15:332\u2013334","journal-title":"Clin Breast Cancer"},{"key":"6188_CR34","doi-asserted-by":"publisher","first-page":"66","DOI":"10.2174\/1574887113666181120111104","volume":"14","author":"P Tiziana","year":"2019","unstructured":"Tiziana P, Alessandra H, Federica A et al (2019) Hair loss prevention by a scalp cooling device in early breast cancer patients: the Poliambulanza preliminary experience. Rev Recent Clin Trials 14:66\u201371","journal-title":"Rev Recent Clin Trials"},{"key":"6188_CR35","doi-asserted-by":"publisher","first-page":"3337","DOI":"10.2217\/fon-2019-0066","volume":"15","author":"O Laura","year":"2019","unstructured":"Laura O, Dario L, Palma F et al (2019) Final results of a prospective study of scalp cooling in preventing chemotherapy-induced alopecia. Future Oncol 15:3337\u20133344","journal-title":"Future Oncol"},{"key":"6188_CR36","doi-asserted-by":"publisher","first-page":"157","DOI":"10.4103\/ijc.IJC_581_17","volume":"55","author":"S Marniza","year":"2018","unstructured":"Marniza S, Tze CFL, Zarina BA et al (2018) The efficacy and tolerability of scalp cooling in preventing chemotherapy-induced alopecia in patients with breast cancer receiving anthracycline and taxane-based chemotherapy in an Asian setting. Indian J Cancer 55:157\u2013161","journal-title":"Indian J Cancer"},{"key":"6188_CR37","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1038\/s41416-019-0520-8","volume":"121","author":"M Elisabetta","year":"2019","unstructured":"Elisabetta M, Vincenzo B, Giuseppe C et al (2019) Preventing chemotherapy-induced alopecia: a prospective clinical trial on the efficacy and safety of a scalp-cooling system in early breast cancer patients treated with anthracyclines. Br J Cancer 121:325\u2013331","journal-title":"Br J Cancer"},{"key":"6188_CR38","first-page":"e12888","volume":"undefined","author":"P Rebecca","year":"2020","unstructured":"Rebecca P, Carla F, di Mauro P et al (2020) Efficacy of the DigniCap System in preventing chemotherapy-induced alopecia in breast cancer patients is not related to patient characteristics or side effects of the device. Int J Nurs Pract undefined:e12888.\u00a0","journal-title":"Int J Nurs Pract"},{"key":"6188_CR39","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1007\/s10549-018-4983-8","volume":"173","author":"S Katharina","year":"2019","unstructured":"Katharina S, Philippe J, Manuel F et al (2019) COOLHAIR: a prospective randomized trial to investigate the efficacy and tolerability of scalp cooling in patients undergoing (neo)adjuvant chemotherapy for early breast cancer. Breast Cancer Res Treat 173:135\u2013143","journal-title":"Breast Cancer Res Treat"},{"key":"6188_CR40","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1159\/000440636","volume":"38","author":"S-N D\u00f6rthe","year":"2015","unstructured":"D\u00f6rthe S-N, Inge S, Anke J-N et al (2015) The influence of various parameters on the success of sensor-controlled scalp cooling in preventing chemotherapy-induced alopecia. Oncol Res Treat 38:489\u2013495","journal-title":"Oncol Res Treat"},{"key":"6188_CR41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.breast.2018.04.012","volume":"40","author":"V Ines","year":"2018","unstructured":"Ines V, Alexandra W, Winfried S (2018) Scalp cooling successfully prevents alopecia in breast cancer patients undergoing anthracycline\/taxane-based chemotherapy. Breast 40:1\u20133","journal-title":"Breast"},{"key":"6188_CR42","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1002\/pon.1615","volume":"19","author":"CJG van den Hurk","year":"2010","unstructured":"van den Hurk CJG, Floortje M, Vingerhoets Ad JJM et al (2010) Impact of alopecia and scalp cooling on the well-being of breast cancer patients. Psychooncology 19:701\u2013709","journal-title":"Psychooncology"},{"key":"6188_CR43","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s00520-008-0475-4","volume":"17","author":"M Floortje","year":"2009","unstructured":"Floortje M, van den Hurk CJ, Vingerhoets Ad JJM et al (2009) Scalp cooling to prevent chemotherapy-induced hair loss: practical and clinical considerations. Support Care Cancer 17:181\u2013189","journal-title":"Support Care Cancer"},{"key":"6188_CR44","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1007\/BF01262571","volume":"5","author":"IG Ron","year":"1997","unstructured":"Ron IG, Kalmus Y, Kalmus Z, Inbar M, Chaitchik S (1997) Scalp cooling in the prevention of alopecia in patients receiving depilating chemotherapy. Support Care Cancer 5:136\u2013138","journal-title":"Support Care Cancer"},{"issue":"18","key":"6188_CR45","first-page":"2244","volume":"31","author":"Y Li","year":"2017","unstructured":"Li Y, Fengli LU, Dongsheng Z (2017) Study on scalp cooling therapy for prevention of hair loss in patients with breast cancer chemotherapy and its influencing factors. Nurs Res 31(18):2244\u20132246","journal-title":"Nurs Res"},{"key":"6188_CR46","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.breast.2019.12.004","volume":"49","author":"J Bajpai","year":"2020","unstructured":"Bajpai J, Kagwade S, Chandrasekharan A, Dandekar S, Kanan S, Kembhavi Y, Ghosh J, Banavali SD, Gupta S (2020) Randomised controlled trial of scalp cooling for the prevention of chemotherapy induced alopecia. Breast 49:187\u2013193","journal-title":"Breast"},{"key":"6188_CR47","doi-asserted-by":"publisher","first-page":"733","DOI":"10.3389\/fonc.2019.00733","volume":"9","author":"K Takayuki","year":"2019","unstructured":"Takayuki K, Takahiro N, Eisuke F et al (2019) Efficacy of scalp cooling in preventing and recovering from chemotherapy-induced alopecia in breast cancer patients: the HOPE study. Front Oncol 9:733","journal-title":"Front Oncol"},{"key":"6188_CR48","doi-asserted-by":"crossref","unstructured":"Franz-Ferdinand Bitto, Alexander K\u00f6nig, Thuy\u00a0 Phan-Brehm, Thomas Vallbracht, Julian\u00a0Gregor Koch, Timo Schink\u00f6the, Matthias Wolfgarten, Sven Mahner, Nadia Harbeck, Rachel W\u00fcrstlein, (2020) EVA-Scalp: Evaluation of Patient Satisfaction with a Scalp Cooling Device to Prevent Chemotherapy-Induced Alopecia in Breast Cancer Patients. Breast Care 15 (2):171-177","DOI":"10.1159\/000501393"},{"key":"6188_CR49","unstructured":"Fan C, Liang Y, Dawei Z et al (2018) Application of scalp cooling cap to reduce alopecia in breast cancer patients with neoadjuvant chemotherapy. Chin J Mammary Gland Diseas 12(06):340\u2013345"},{"key":"6188_CR50","doi-asserted-by":"crossref","unstructured":"Tommaso G, Simona F, Monica Z et al (2020) Use of scalp cooling device to prevent alopecia for early breast cancer patients receiving chemotherapy: a prospective study. Breast J 26:1296\u20131301","DOI":"10.1111\/tbj.13711"},{"key":"6188_CR51","doi-asserted-by":"crossref","unstructured":"Shozo O, Sachiko K, Mina T et al (2021) Scalp cooling for hair loss prevention in female Japanese breast cancer patients receiving (neo)adjuvant chemotherapy. Support Care Cancer 29:437\u2013443","DOI":"10.1007\/s00520-020-05506-w"},{"key":"6188_CR52","doi-asserted-by":"crossref","unstructured":"\u200bRice Brooke A (2018) Ver Hoeve Elizabeth S, DeLuca Amy N et al. Registry study to assess hair loss prevention with the Penguin Cold Cap in breast cancer patients receiving chemotherapy. Breast Cancer Res Treat 167:117\u2013122","DOI":"10.1007\/s10549-017-4506-z"},{"key":"6188_CR53","doi-asserted-by":"crossref","unstructured":"Mustoe Mollie M, Lee Carmen M, Melisko Michelle E et al (2018) The DigniCap Scalp Cooling System and its use in the treatment of chemotherapy-induced alopecia. Future Oncol 14:2461\u20132469","DOI":"10.2217\/fon-2018-0178"},{"key":"6188_CR54","doi-asserted-by":"crossref","unstructured":"Mikel R, Erica F-C (2017) Scalp cooling: a literature review of efficacy, safety, and tolerability for chemotherapy-induced alopecia. Clin J Oncol Nurs 21:226\u2013233","DOI":"10.1188\/17.CJON.226-233"},{"key":"6188_CR55","doi-asserted-by":"crossref","unstructured":"Mart\u00edn M, de la Torre-Montero JC, L\u00f3pez-Tarruella S, Pinilla K, Casado A, Fernandez S, Jerez Y, Puente J, Palomero I, Gonz\u00e1lez del Val R, del Monte-Millan M, Massarrah T, Vila C, Garc\u00eda-Paredes B, Garc\u00eda-S\u00e1enz JA, Lluch A (2018) Persistent major alopecia following adjuvant docetaxel for breast cancer: incidence, characteristics, and prevention with scalp cooling. Breast Cancer Res Treat 171:627\u2013634","DOI":"10.1007\/s10549-018-4855-2"},{"key":"6188_CR56","doi-asserted-by":"crossref","unstructured":"Jung-Woo C, Raymond N, Alexandre C (2018) Chemotherapy drug concentrations in hair follicles: a potential biomarker to monitor the effectiveness of scalp cooling for chemotherapy-induced alopecia. Support Care Cancer 26:3669\u20133670","DOI":"10.1007\/s00520-018-4324-9"},{"key":"6188_CR57","doi-asserted-by":"crossref","unstructured":"Megan K, Jame A (2018) Management of chemotherapy-induced alopecia with scalp cooling. J Oncol Pract 14:149\u2013154","DOI":"10.1200\/JOP.17.00038"},{"key":"6188_CR58","doi-asserted-by":"crossref","unstructured":"Kaarina AP, Annikki MU, Marika SK et al (2010) The effectiveness of a scalp cooling cap in preventing chemotherapy-induced alopecia. Tumori 96:271\u2013275","DOI":"10.1177\/030089161009600214"},{"key":"6188_CR59","doi-asserted-by":"crossref","unstructured":"Mona R, Maria B, Anita G (2003) Scalp hypothermia to prevent chemotherapy-induced alopecia is effective and safe: a pilot study of a new digitized scalp-cooling system used in 74 patients. Support Care Cancer 11:371\u2013377","DOI":"10.1007\/s00520-003-0451-y"},{"key":"6188_CR60","doi-asserted-by":"crossref","unstructured":"Gulbeyaz C, Melike D, Ozgul E et al (2013) A comparison of men and women\u2019s experiences of chemotherapy-induced alopecia. Eur J Oncol Nurs 17:255\u2013260","DOI":"10.1016\/j.ejon.2012.06.003"},{"key":"6188_CR61","doi-asserted-by":"crossref","unstructured":"Azael F-M, Jerry S, Shari G et al (2019) Hair disorders in patients with cancer. J Am Acad Dermatol 80:1179\u20131196","DOI":"10.1016\/j.jaad.2018.03.055"},{"key":"6188_CR62","doi-asserted-by":"crossref","unstructured":"B\u00fclow J, Friberg L, Gaardsting O, Hansen M (1985) Frontal subcutaneous blood flow, and epi- and subcutaneous temperatures during scalp cooling in normal man. Scand J Clin Lab Invest 45:505\u2013508","DOI":"10.3109\/00365518509155250"},{"key":"6188_CR63","doi-asserted-by":"crossref","unstructured":"Christodoulou C, Tsakalos G, Galani E, Skarlos DV (2006) Scalp metastases and scalp cooling for chemotherapy-induced alopecia prevention. Ann Oncol 17:350","DOI":"10.1093\/annonc\/mdj008"},{"key":"6188_CR64","doi-asserted-by":"crossref","unstructured":"Gregory RP, Cooke T, Middleton J et al (1982) Prevention of doxorubicin-induced alopedia by scalp hypothermia: relation to degree of cooling. Br Med J (Clin Res Ed) 284:1674","DOI":"10.1136\/bmj.284.6330.1674"},{"key":"6188_CR65","doi-asserted-by":"crossref","unstructured":"Komen MMC, Smorenburg CH, Nortier JWR, van der Ploeg T, van den Hurk CJG, van der Hoeven JJM (2016) Results of scalp cooling during anthracycline containing chemotherapy depend on scalp skin temperature. Breast 30:105\u2013110","DOI":"10.1016\/j.breast.2016.09.007"},{"key":"6188_CR66","doi-asserted-by":"crossref","unstructured":"Rugo Hope S, Melin Susan A (2017) Voigt Jeff, Scalp cooling with adjuvant\/neoadjuvant chemotherapy for breast cancer and the risk of scalp metastases: systematic review and meta-analysis. Breast Cancer Res Treat 163:199\u2013205","DOI":"10.1007\/s10549-017-4185-9"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-021-06188-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-021-06188-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-021-06188-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,25]],"date-time":"2021-09-25T04:04:00Z","timestamp":1632542640000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-021-06188-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,13]]},"references-count":66,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["6188"],"URL":"https:\/\/doi.org\/10.1007\/s00520-021-06188-8","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,13]]},"assertion":[{"value":"26 December 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 March 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 April 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"As this is a systematic review reporting on existing data, ethics approval was not required.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors are responsible for the correctness of the statements provided in the manuscript. There was no need to obtain permission from any person for publication of this review.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}