{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:46:19Z","timestamp":1790858779722,"version":"4.1.0"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T00:00:00Z","timestamp":1637625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T00:00:00Z","timestamp":1637625600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract\n<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>The aim of this study was to explore the beliefs, perceptions and representations of patients in order to identify the determinants of oral anticancer drugs adherence and to take action in current practice to improve patient support in digestive oncology.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We constructed a semi-directed interview guide which aimed to explore the patient\u2019s relationship with medication, their health history, their experiences at the time of the announcement of treatment, their confidence, their fears, their motivations to adhere to their treatment and the constraints linked to their treatment. The data were analysed and discussed using a thematic approach.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Seventeen patients agreed to participate in the study. The median age was 60\u00a0years. Ten patients had colorectal cancer, 3 patients had hepatocellular carcinoma, 3 patients had gastrointestinal stromal tumour and 1 patient had neuroendocrine pancreatic tumour. We identified five categories of factors influencing adherence: demographic and socioeconomic, disease-related, treatment-related, care system-related, and patient representation and pathways\u2019 factors. A majority of patients emphasised the importance of family support in the adherence process and the convenience of per os treatment compared to other intravenous treatments. However, several negative determinants emerged such as the toxicity of the treatment, fears of forgetting to take the medication, difficulties with the galenic formulation and negative beliefs of the family.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This study demonstrates the need to address the different dimensions of the patient in order to understand his or her behaviour with regard to adherence and to identify the levers for improvement.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00520-021-06663-2","type":"journal-article","created":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T11:02:44Z","timestamp":1637665364000},"page":"2591-2604","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Exploring the factors influencing adherence to oral anticancer drugs in patients with digestive cancer: a qualitative study"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6912-0025","authenticated-orcid":false,"given":"Pierre","family":"Nizet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yann","family":"Touchefeu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solange","family":"Pecout","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estelle","family":"Cauchin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Beaudouin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9verine","family":"Mayol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9mentine","family":"Fronteau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Fran\u00e7ois","family":"Huon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,11,23]]},"reference":[{"key":"6663_CR1","unstructured":"Haynes RB, Taylor DW, Sackett DL, \u00e9diteurs. Compliance in health care. Baltimore: Johns Hopkins University Press; 1979."},{"issue":"6","key":"6663_CR2","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/j.pharma.2018.07.006","volume":"76","author":"B Allenet","year":"2018","unstructured":"Allenet B, Lehmann A, Baudrant M, Gauchet A (2018) Il nous faut arr\u00eater de parler du patient \u00ab\u202fnon observant\u202f\u00bb \u00e0 ses traitements mais plut\u00f4t d\u2019un patient pr\u00e9sentant des difficult\u00e9s d\u2019adh\u00e9sion m\u00e9dicamenteuse. Annales Pharmaceutiques Fran\u00e7aises 76(6):489\u201398","journal-title":"Annales Pharmaceutiques Fran\u00e7aises"},{"key":"6663_CR3","unstructured":"Beauvais C. 2007 Quand prescrire ne suffit plus\u2026 L\u2019observance th\u00e9rapeutique: un enjeu pour les rhumatologues \u2013 adherence to medication: a challenge for patients and rheumatologists. \u00c9 ditorial. d\u00e9c;4."},{"key":"6663_CR4","unstructured":"Adh\u00e9sion, observance et persistance th\u00e9rapeutiques: de quoi parle-t-on? [Internet]. WeLL. 2018 [cit\u00e9 21 mars 2021]. Disponible sur: http:\/\/well-livinglab.be\/adhesion-observance-persistance-therapeutique-de-quoi-parle-t-on\/"},{"issue":"2","key":"6663_CR5","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.pharma.2012.10.001","volume":"71","author":"B Allenet","year":"2013","unstructured":"Allenet B, Baudrant M, Lehmann A, Gauchet A, Roustit M, Bedouch P et al (2013) Comment \u00e9valuer l\u2019adh\u00e9sion m\u00e9dicamenteuse\u202f? Le point sur les m\u00e9thodes. Annales Pharmaceutiques Fran\u00e7aises 71(2):135\u201341","journal-title":"Annales Pharmaceutiques Fran\u00e7aises"},{"key":"6663_CR6","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.2147\/PPA.S164686","volume":"12","author":"A Giardini","year":"2018","unstructured":"Giardini A, Maffoni M, Kardas P, Costa E (2018) A cornerstone of healthy aging: do we need to rethink the concept of adherence in the elderly? Patient Prefer Adherence 12:1003\u20131005","journal-title":"Patient Prefer Adherence"},{"issue":"3","key":"6663_CR7","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1007\/s41999-020-00313-2","volume":"11","author":"M Maffoni","year":"2020","unstructured":"Maffoni M, Traversoni S, Costa E, Mid\u00e3o L, Kardas P, Kurczewska-Michalak M et al (2020) Medication adherence in the older adults with chronic multimorbidity: a systematic review of qualitative studies on patient\u2019s experience. Eur Geriatr Med juin 11(3):369\u2013381","journal-title":"Eur Geriatr Med juin"},{"issue":"10","key":"6663_CR8","doi-asserted-by":"publisher","first-page":"1740","DOI":"10.1007\/s12325-016-0394-6","volume":"33","author":"N Pag\u00e8s-Puigdemont","year":"2016","unstructured":"Pag\u00e8s-Puigdemont N, Mangues MA, Masip M, Gabriele G, Fern\u00e1ndez-Maldonado L, Blancafort S et al (2016) Patients\u2019 perspective of medication adherence in chronic conditions: a qualitative study. Adv Ther 33(10):1740\u20131754","journal-title":"Adv Ther"},{"issue":"9","key":"6663_CR9","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1038\/sj.bjc.6600591","volume":"87","author":"VJ O\u2019Neill","year":"2002","unstructured":"O\u2019Neill VJ, Twelves CJ (2002) Oral cancer treatment: developments in chemotherapy and beyond. Br J Cancer 87(9):933\u20137","journal-title":"Br J Cancer"},{"key":"6663_CR10","unstructured":"Baudrant M, Lehmann A, Allenet B. 2012 Penser autrement l\u2019observance m\u00e9dicamenteuse: d\u2019une posture injonctive \u00e0 une alliance th\u00e9rapeutique entre le patient et le soignant \u2013 concepts et d\u00e9terminants. Annales Pharmaceutiques Francaises. f\u00e9vr"},{"issue":"6","key":"6663_CR11","doi-asserted-by":"publisher","first-page":"E20","DOI":"10.1097\/NCC.0b013e3181b31114","volume":"32","author":"V Decker","year":"2009","unstructured":"Decker V, Spoelstra S, Miezo E, Bremer R, You M, Given C et al (2009) A pilot study of an automated voice response system and nursing intervention to monitor adherence to oral chemotherapy agents. Cancer Nurs d\u00e9c 32(6):E20-29","journal-title":"Cancer Nurs d\u00e9c"},{"issue":"7","key":"6663_CR12","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1007\/s00520-010-0927-5","volume":"19","author":"S Simons","year":"2011","unstructured":"Simons S, Ringsdorf S, Braun M, Mey UJ, Schwindt PF, Ko YD et al (2011) Enhancing adherence to capecitabine chemotherapy by means of multidisciplinary pharmaceutical care. Support Care Cancer juill 19(7):1009\u20131018","journal-title":"Support Care Cancer juill"},{"issue":"4","key":"6663_CR13","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1111\/j.1365-2354.2006.00758.x","volume":"16","author":"PW Macintosh","year":"2007","unstructured":"Macintosh PW, Pond GR, Pond BJ, Leung V, Siu LL (2007) A comparison of patient adherence and preference of packaging method for oral anticancer agents using conventional pill bottles versus daily pill boxes. Eur J Cancer Care (Engl) 16(4):380\u20136","journal-title":"Eur J Cancer Care (Engl)"},{"issue":"3","key":"6663_CR14","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1177\/1078155211436022","volume":"18","author":"D Bhattacharya","year":"2012","unstructured":"Bhattacharya D, Easthall C, Willoughby KA, Small M, Watson S (2012) Capecitabine non-adherence: exploration of magnitude, nature and contributing factors. J Oncol Pharm Pract sept 18(3):333\u2013342","journal-title":"J Oncol Pharm Pract sept"},{"issue":"9","key":"6663_CR15","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1093\/jnci\/94.9.652","volume":"94","author":"AH Partridge","year":"2002","unstructured":"Partridge AH, Avorn J, Wang PS, Winer EP (2002) Adherence to therapy with oral antineoplastic agents. J Natl Cancer Inst 94(9):652\u201361","journal-title":"J Natl Cancer Inst"},{"key":"6663_CR16","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.ejon.2018.11.004","volume":"38","author":"L Iacorossi","year":"2019","unstructured":"Iacorossi L, Gambalunga F, De Domenico R, Serra V, Marzo C, Carlini P (2019) Qualitative study of patients with metastatic prostate cancer to adherence of hormone therapy. Eur J Oncol Nurs f\u00e9vr 38:8\u201312","journal-title":"Eur J Oncol Nurs f\u00e9vr"},{"issue":"10","key":"6663_CR17","doi-asserted-by":"publisher","first-page":"4123","DOI":"10.1007\/s00520-016-3229-8","volume":"24","author":"KJ Wells","year":"2016","unstructured":"Wells KJ, Pan TM, V\u00e1zquez-Otero C, Ung D, Ustjanauskas AE, Mu\u00f1oz D et al (2016) Barriers and facilitators to endocrine therapy adherence among underserved hormone-receptor-positive breast cancer survivors: a qualitative study. Support Care Cancer 24(10):4123\u20134130","journal-title":"Support Care Cancer"},{"key":"6663_CR18","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1111\/ecc.12339","volume":"26","author":"M Verbrugghe","year":"2017","unstructured":"Verbrugghe M, Verhaeghe S, Decoene E, De Baere S, Vandendorpe B, Van Hecke A (2017) Factors influencing the process of medication (non-)adherence and (non-)persistence in breast cancer patients with adjuvant antihormonal therapy: a qualitative study. Eur J Cancer Care (Engl) 26:2","journal-title":"Eur J Cancer Care (Engl)"},{"issue":"2","key":"6663_CR19","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1097\/NCC.0000000000000250","volume":"39","author":"M Verbrugghe","year":"2016","unstructured":"Verbrugghe M, Duprez V, Beeckman D, Grypdonck M, Quaghebeur M, Verschueren C et al (2016) Factors influencing adherence in cancer patients taking oral tyrosine kinase inhibitors: a qualitative study. Cancer Nurs avr 39(2):153\u2013162","journal-title":"Cancer Nurs avr"},{"issue":"6","key":"6663_CR20","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1016\/j.rhum.2014.07.010","volume":"81","author":"A-L Betegnie","year":"2014","unstructured":"Betegnie A-L, Lehmann A, Baudrant M, Roustit M, Bedouch P, Grange L et al (2014) Adh\u00e9sion aux bioth\u00e9rapies dans les rhumatismes inflammatoires identifier les leviers pour mieux accompagner le patient. Revue du Rhumatisme 81(6):472\u20137","journal-title":"Revue du Rhumatisme"},{"key":"6663_CR21","unstructured":"Patton MQ. Qualitative evaluation and research methods, 2nd ed. Thousand Oaks, CA, US: Sage Publications, Inc; 1990. 532 p. (Qualitative evaluation and research methods, 2nd ed)."},{"key":"6663_CR22","unstructured":"Strauss A, Corbin JM. Basics of qualitative research: grounded theory procedures and techniques. Thousand Oaks, CA, US: Sage Publications, Inc; 1990. 270 p. (Basics of qualitative research: grounded theory procedures and techniques)."},{"key":"6663_CR23","unstructured":"Glaser BG, Strauss AA. La d\u00e9couverte de la th\u00e9orie ancr\u00e9e. http:\/\/journals.openedition.org\/lectures. :409."},{"issue":"10","key":"6663_CR24","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1046\/j.1525-1497.2002.11214.x","volume":"17","author":"CE Golin","year":"2002","unstructured":"Golin CE, Liu H, Hays RD, Miller LG, Beck CK, Ickovics J et al (2002) A prospective study of predictors of adherence to combination antiretroviral medication. J Gen Intern Med 17(10):756\u2013765","journal-title":"J Gen Intern Med"},{"issue":"1","key":"6663_CR25","first-page":"34","volume":"15","author":"RJ Julius","year":"2009","unstructured":"Julius RJ, Novitsky MA, Dubin WR (2009) Medication adherence: a review of the literature and implications for clinical practice. J Psychiatr Pract janv 15(1):34\u201344","journal-title":"J Psychiatr Pract janv"},{"issue":"6","key":"6663_CR26","doi-asserted-by":"publisher","first-page":"1525","DOI":"10.1007\/s11606-021-06704-w","volume":"36","author":"O Cohen Castel","year":"2021","unstructured":"Cohen Castel O, Dagan E, Keinan-Boker L, Low M, Shadmi E (2021) Patients\u2019 perceived continuity of care and adherence to oral anticancer therapy: a prospective cohort mediation study. J Gen Intern Med 36(6):1525\u20131532","journal-title":"J Gen Intern Med"},{"issue":"7316","key":"6663_CR27","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1136\/bmj.323.7316.784","volume":"323","author":"SM Campbell","year":"2001","unstructured":"Campbell SM, Hann M, Hacker J, Burns C, Oliver D, Thapar A et al (2001) Identifying predictors of high quality care in English general practice: observational study. BMJ 323(7316):784\u20137","journal-title":"BMJ"},{"issue":"4 Suppl 2","key":"6663_CR28","doi-asserted-by":"publisher","first-page":"S17","DOI":"10.1016\/j.soncn.2007.10.004","volume":"23","author":"FM Palmieri","year":"2007","unstructured":"Palmieri FM, Barton DL (2007) Challenges of oral medications in patients with advanced breast cancer. Semin Oncol Nurs 23(4 Suppl 2):S17-22","journal-title":"Semin Oncol Nurs"},{"issue":"2","key":"6663_CR29","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1188\/08.CJON.213-221","volume":"12","author":"C Miaskowski","year":"2008","unstructured":"Miaskowski C, Shockney L, Chlebowski RT (2008) Adherence to oral endocrine therapy for breast cancer: a nursing perspective. Clin J Oncol Nurs avr 12(2):213\u2013221","journal-title":"Clin J Oncol Nurs avr"},{"issue":"1","key":"6663_CR30","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/S0738-3991(03)00017-X","volume":"52","author":"J Harrington","year":"2004","unstructured":"Harrington J, Noble LM, Newman SP (2004) Improving patients\u2019 communication with doctors: a systematic review of intervention studies. Patient Educ Couns janv 52(1):7\u201316","journal-title":"Patient Educ Couns janv"},{"issue":"2","key":"6663_CR31","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1016\/j.pec.2006.09.007","volume":"65","author":"P Duberstein","year":"2007","unstructured":"Duberstein P, Meldrum S, Fiscella K, Shields CG, Epstein RM (2007) Influences on patients\u2019 ratings of physicians: physicians demographics and personality. Patient Educ Couns f\u00e9vr 65(2):270\u2013274","journal-title":"Patient Educ Couns f\u00e9vr"},{"issue":"1","key":"6663_CR32","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.pec.2006.09.013","volume":"66","author":"JN Fuertes","year":"2007","unstructured":"Fuertes JN, Mislowack A, Bennett J, Paul L, Gilbert TC, Fontan G et al (2007) The physician-patient working alliance. Patient Educ Couns avr 66(1):29\u201336","journal-title":"Patient Educ Couns avr"},{"issue":"9","key":"6663_CR33","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1016\/0277-9536(95)00061-B","volume":"41","author":"G Makoul","year":"1995","unstructured":"Makoul G, Arntson P, Schofield T (1995) Health promotion in primary care: physician-patient communication and decision making about prescription medications. Soc Sci Med 41(9):1241\u20131254","journal-title":"Soc Sci Med"},{"issue":"9","key":"6663_CR34","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1345\/aph.1L093","volume":"42","author":"DL Keller","year":"2008","unstructured":"Keller DL, Wright J, Pace HA (2008) Impact of health literacy on health outcomes in ambulatory care patients: a systematic review. Ann Pharmacother sept 42(9):1272\u20131281","journal-title":"Ann Pharmacother sept"},{"issue":"3","key":"6663_CR35","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1177\/1078155215581524","volume":"22","author":"LM Holle","year":"2016","unstructured":"Holle LM, Puri S, Clement JM (2016) Physician-pharmacist collaboration for oral chemotherapy monitoring: insights from an academic genitourinary oncology practice. J Oncol Pharm Pract juin 22(3):511\u2013516","journal-title":"J Oncol Pharm Pract juin"},{"issue":"5","key":"6663_CR36","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1177\/1078155217703790","volume":"24","author":"A Divakaruni","year":"2018","unstructured":"Divakaruni A, Saylor E, Duffy AP (2018) Assessing the need for improved strategies and medication-related education to increase adherence for oral anticancer medications in the young adult oncology population. J Oncol Pharm Pract juill 24(5):337\u2013342","journal-title":"J Oncol Pharm Pract juill"},{"issue":"3","key":"6663_CR37","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1007\/s10269-005-0192-2","volume":"7","author":"R Aubry","year":"2005","unstructured":"Aubry R, D\u2019H\u00e9rouville D, Dayde MC, Hirsch G (2005) Soins palliatifs et soins de support. Oncologie 7(3):203\u20138","journal-title":"Oncologie"},{"key":"6663_CR38","unstructured":"Association Francophone de Diffusion de l\u2019Entretien Motivationnel. L\u2019entretien Motivationnel [Internet]. AFDEM. 2018 [cit\u00e9 11 mai 2021]. Disponible sur: https:\/\/afdem.org\/entretienmotivationnel\/"},{"issue":"9","key":"6663_CR39","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.2337\/diacare.22.9.1445","volume":"22","author":"L Du Pasquier-Fediaevsky","year":"1999","unstructured":"Du Pasquier-Fediaevsky L, Tubiana-Rufi N (1999) Discordance between physician and adolescent assessments of adherence to treatment: influence of HbA1c level. The PEDIAB Collaborative Group. Diabetes Care 22(9):1445\u20139","journal-title":"Diabetes Care"},{"issue":"3","key":"6663_CR40","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/0277-9536(88)90132-3","volume":"27","author":"LD Ried","year":"1988","unstructured":"Ried LD, Christensen DB (1988) A psychosocial perspective in the explanation of patients\u2019 drug-taking behavior. Soc Sci Med 27(3):277\u2013285","journal-title":"Soc Sci Med"},{"issue":"1","key":"6663_CR41","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1258\/095646204322637245","volume":"15","author":"R Horne","year":"2004","unstructured":"Horne R, Buick D, Fisher M, Leake H, Cooper V, Weinman J (2004) Doubts about necessity and concerns about adverse effects: identifying the types of beliefs that are associated with non-adherence to HAART. Int J STD AIDS janv 15(1):38\u201344","journal-title":"Int J STD AIDS janv"},{"issue":"12","key":"6663_CR42","doi-asserted-by":"publisher","first-page":"2123","DOI":"10.1345\/aph.1H355","volume":"40","author":"J George","year":"2006","unstructured":"George J, Munro K, McCaig DJ, Stewart DC (2006) Prescription medications: beliefs, experiences, behavior, and adherence of sheltered housing residents. Ann Pharmacother d\u00e9c 40(12):2123\u20132129","journal-title":"Ann Pharmacother d\u00e9c"},{"issue":"7","key":"6663_CR43","doi-asserted-by":"publisher","first-page":"657","DOI":"10.2146\/ajhp080064","volume":"66","author":"ME Gatti","year":"2009","unstructured":"Gatti ME, Jacobson KL, Gazmararian JA, Schmotzer B, Kripalani S (2009) Relationships between beliefs about medications and adherence. Am J Health Syst Pharm 66(7):657\u201364","journal-title":"Am J Health Syst Pharm"},{"issue":"6","key":"6663_CR44","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1016\/S0022-3999(99)00057-4","volume":"47","author":"R Horne","year":"1999","unstructured":"Horne R, Weinman J (1999) Patients\u2019 beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. J Psychosom Res d\u00e9c 47(6):555\u2013567","journal-title":"J Psychosom Res d\u00e9c"},{"issue":"1","key":"6663_CR45","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1037\/h0092976","volume":"80","author":"JB Rotter","year":"1966","unstructured":"Rotter JB (1966) Generalized expectancies for internal versus external control of reinforcement. Psychol Monogr 80(1):1\u201328","journal-title":"Psychol Monogr"},{"issue":"6","key":"6663_CR46","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1016\/S1957-2557(18)30134-2","volume":"12","author":"PY Benhamou","year":"2018","unstructured":"Benhamou PY (2018) L\u2019observance th\u00e9rapeutique \u00e0 l\u2019heure du num\u00e9rique et des objets connect\u00e9s. M\u00e9decine des Maladies M\u00e9taboliques 12(6):502\u201310","journal-title":"M\u00e9decine des Maladies M\u00e9taboliques"},{"issue":"10","key":"6663_CR47","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1684\/bdc.2014.1950","volume":"101","author":"B Brouard","year":"2014","unstructured":"Brouard B, Bardo P, Vignot M, Bonnet C, Vignot S (2014) E-sant\u00e9 et m-sant\u00e9: \u00e9tat des lieux en 2014 et apports potentiels en oncologie. Bulletin du Cancer 101(10):940\u201350","journal-title":"Bulletin du Cancer"},{"key":"6663_CR48","unstructured":"M\u00e9liani V. Choisir l\u2019analyse par th\u00e9orisation ancr\u00e9e: illustration des apports et des limites de la m\u00e9thode. :18."}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-021-06663-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-021-06663-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-021-06663-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T08:14:47Z","timestamp":1643271287000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-021-06663-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,23]]},"references-count":48,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["6663"],"URL":"https:\/\/doi.org\/10.1007\/s00520-021-06663-2","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,23]]},"assertion":[{"value":"3 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 October 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 November 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Approval was obtained from the \u201cGroupe Nantais d\u2019Ethique dans le Domaine de la Sant\u00e9\u201d (GNEDS). The procedures used in this study adhere to the tenets of the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"NA","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest\/competing interests"}}]}}