{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:13:40Z","timestamp":1792091620140,"version":"4.4.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T00:00:00Z","timestamp":1647648000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T00:00:00Z","timestamp":1647648000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Malcolm Coptcoat Trust"},{"name":"King's Medical Research Trust"},{"name":"Medical Research Council Centre for Transplantation"},{"name":"KCL-Vattikuti Institute of Robotic Surgery"},{"name":"GSTT Charity"},{"name":"The Urology Foundation"},{"DOI":"10.13039\/501100000872","name":"Pelican Cancer Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000872","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the National Institute for Health Research (NIHR) Biomedical Research Centre"},{"name":"Medical Research Council (MRC) DATAMIND HDR-UK mental health data hub"},{"name":"NIHR Senior Investigator Award"},{"DOI":"10.13039\/501100000297","name":"Royal College of Surgeons of England","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000297","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>There is a growing emphasis on improving quality of life of people with prostate cancer. However, those undergoing active surveillance remain underrepresented in the literature with less known about their unique challenges. Therefore, we aimed to explore their lived experiences post diagnosis and its effect on their mental, social, and physical wellbeing.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Qualitative semi-structured interviews were conducted with 13 men undergoing active surveillance for low-risk disease. Thematic analysis was used to inductively co-construct themes through the lens of the biopsychosocial model.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Mental wellbeing was strongly affected in our participants due to the overwhelming emotional impact of their diagnosis resulting in an \u2018Emotional Diagnostic Disequilibrium\u2019. Informational awareness and education about prostate cancer helped patients with \u2018Recognition of the Impact\u2019. Patients experienced an \u2018Unsettling Monitoring Cycle\u2019 due to the increased fear and anxiety around PSA monitoring appointments, with some men ignoring their mental wellbeing needs as their disease is \u2018A Future Problem\u2019. \u2018Concealment of Diagnosis\u2019 left many feeling isolated and highlighted an important coping mechanisms in the \u2018Importance of a Social Support Network\u2019 theme. Finally, physical health mostly changed through alterations in health behaviour, leading to \u2018A Healthier Lifestyle\u2019 with increasing attribution of physical symptoms to age through \u2018Symptomatic Overshadowing\u2019.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The greatest disease impact on men\u2019s wellbeing was at the time of diagnosis, with a subsequent cyclical anxiety and fear of disease progression prominent around monitoring appointments. Future research should explore ways to better support patients with these issues and at these times, improving their quality of life.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00520-022-06976-w","type":"journal-article","created":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T03:02:37Z","timestamp":1647658957000},"page":"5459-5468","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["An exploration of wellbeing in men diagnosed with prostate cancer undergoing active surveillance: a qualitative study"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2691-0072","authenticated-orcid":false,"given":"Omar","family":"Eymech","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2073-922X","authenticated-orcid":false,"given":"Oliver","family":"Brunckhorst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8280-1797","authenticated-orcid":false,"given":"Louis","family":"Fox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8292-9707","authenticated-orcid":false,"given":"Anam","family":"Jawaid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7317-0858","authenticated-orcid":false,"given":"Mieke","family":"Van Hemelrijck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4435-6397","authenticated-orcid":false,"given":"Robert","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8690-0445","authenticated-orcid":false,"given":"Prokar","family":"Dasgupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5135-9211","authenticated-orcid":false,"given":"Kamran","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,19]]},"reference":[{"key":"6976_CR1","doi-asserted-by":"publisher","unstructured":"Ferlay J, Colombet M, Soerjomataram I, Dyba T, Randi G, Bettio M, Gavin A et al (2018) Cancer incidence and mortality patterns in Europe: estimates for 40 countries and 25 major cancers in 2018. Eur J Cancer 103:356\u2013387. https:\/\/doi.org\/10.1016\/j.ejca.2018.07.005","DOI":"10.1016\/j.ejca.2018.07.005"},{"issue":"6","key":"6976_CR2","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1016\/j.eururo.2017.06.035","volume":"72","author":"M Lardas","year":"2017","unstructured":"Lardas M, Liew M, van den Bergh RC, De Santis M, Bellmunt J, Van den Broeck T et al (2017) Quality of life outcomes after primary treatment for clinically localised prostate cancer: a systematic review. Eur Urol. 72(6):869\u201385. https:\/\/doi.org\/10.1016\/j.eururo.2017.06.035","journal-title":"Eur Urol."},{"key":"6976_CR3","doi-asserted-by":"publisher","unstructured":"Brunckhorst O, Hashemi S, Martin A, George G, Van Hemelrijck M, Dasgupta P et al (2021) Depression anxiety and suicidality in patients with prostate cancer a systematic review and meta-analysis of observational studies. Prostate Cancer Prostatic Dis 24(2):281\u2013289. https:\/\/doi.org\/10.1038\/s41391-020-00286-0","DOI":"10.1038\/s41391-020-00286-0"},{"key":"6976_CR4","doi-asserted-by":"publisher","unstructured":"Bowie J, Brunckhorst O, Stewart R, Dasgupta P, Ahmed K (2022) Body image, self-esteem, and sense of masculinity in patients with prostate cancer: a qualitative meta-synthesis. J Cancer Surviv 16(1):95\u2013110. https:\/\/doi.org\/10.1007\/s11764-021-01007-9","DOI":"10.1007\/s11764-021-01007-9"},{"issue":"6","key":"6976_CR5","doi-asserted-by":"publisher","first-page":"1703","DOI":"10.1007\/s00520-018-4134-0","volume":"26","author":"N Collaco","year":"2018","unstructured":"Collaco N, Rivas C, Matheson L, Nayoan J, Wagland R, Alexis O et al (2018) Prostate cancer and the impact on couples: a qualitative metasynthesis. Support Care Cancer 26(6):1703\u201313. https:\/\/doi.org\/10.1007\/s00520-018-4134-0","journal-title":"Support Care Cancer"},{"issue":"5","key":"6976_CR6","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1016\/j.jpsychores.2015.09.003","volume":"79","author":"P Henningsen","year":"2015","unstructured":"Henningsen P (2015) Still modern? Developing the biopsychosocial model for the 21st century. J Psychosom Res 79(5):362\u20133. https:\/\/doi.org\/10.1016\/j.jpsychores.2015.09.003","journal-title":"J Psychosom Res"},{"issue":"5","key":"6976_CR7","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1176\/ajp.137.5.535","volume":"137","author":"GL Engel","year":"1980","unstructured":"Engel GL (1980) The clinical application of the biopsychosocial model. Am J Psychiatry 137(5):535\u201344. https:\/\/doi.org\/10.1176\/ajp.137.5.535","journal-title":"Am J Psychiatry"},{"key":"6976_CR8","unstructured":"World Health Organization (2002) Towards a common language for functioning, disability and health ICF. Available from: https:\/\/www.who.int\/classifications\/icf\/icfbeginnersguide.pdf"},{"key":"6976_CR9","unstructured":"European Association of Urology. Prostate cancer guidelines\u00a0(2021). Available from: https:\/\/uroweb.org\/guideline\/prostate-cancer\/."},{"issue":"3","key":"6976_CR10","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1056\/NEJMp1703787","volume":"377","author":"MR Haymart","year":"2017","unstructured":"Haymart MR, Miller DC, Hawley ST (2017) Active surveillance for low-risk cancers - a viable solution to overtreatment? N Engl J Med 377(3):203\u20136. https:\/\/doi.org\/10.1056\/NEJMp1703787","journal-title":"N Engl J Med"},{"key":"6976_CR11","doi-asserted-by":"publisher","unstructured":"Cordova MJ, Riba MB, Spiegel D (2017) Post-traumatic stress disorder and cancer. The Lancet Psychiatry 4(4):330\u2013338. https:\/\/doi.org\/10.1016\/S2215-0366(17)30014-7","DOI":"10.1016\/S2215-0366(17)30014-7"},{"key":"6976_CR12","doi-asserted-by":"publisher","unstructured":"Kettlewell N, Morris RW, Ho N, Cobb-Clark DA, Cripps S, Glozier N (2020) The differential impact of major life events on cognitive and affective wellbeing. SSM - Population Health 10:100533. https:\/\/doi.org\/10.1016\/j.ssmph.2019.100533","DOI":"10.1016\/j.ssmph.2019.100533"},{"key":"6976_CR13","doi-asserted-by":"publisher","unstructured":"Ruane-McAteer E, Prue G (2022) Psychological aspects of active surveillance. World J Urol 40(1):9\u201313. https:\/\/doi.org\/10.1007\/s00345-020-03553-w","DOI":"10.1007\/s00345-020-03553-w"},{"key":"6976_CR14","doi-asserted-by":"publisher","unstructured":"Crump RT, Remmers S, Van Hemelrijck M, Helleman J, Nieboer D, Roobol MJ et al (2021) Using the Movember Foundation\u2019s GAP3 cohort to measure the effect of active surveillance on patient-reported urinary and sexual function-a retrospective study in low-risk prostate cancer patients. Transl Androl Urol 10(6):2719\u20132727. https:\/\/doi.org\/10.21037\/tau-20-1255","DOI":"10.21037\/tau-20-1255"},{"issue":"10","key":"6976_CR15","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.1002\/pon.4311","volume":"26","author":"E Ruane-McAteer","year":"2017","unstructured":"Ruane-McAteer E, Porter S, O\u2019Sullivan JM, Santin O, Prue G (2017) Active surveillance for favorable-risk prostate cancer: is there a greater psychological impact than previously thought? A systematic, mixed studies literature review. Psychooncology 26(10):1411\u201321. https:\/\/doi.org\/10.1002\/pon.4311","journal-title":"Psychooncology"},{"issue":"1","key":"6976_CR16","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1097\/00002820-200302000-00008","volume":"26","author":"O Hedestig","year":"2003","unstructured":"Hedestig O, Sandman PO, Widmark A (2003) Living with untreated localized prostate cancer: a qualitative analysis of patient narratives. Cancer Nurs 26(1):55\u201360. https:\/\/doi.org\/10.1097\/00002820-200302000-00008","journal-title":"Cancer Nurs"},{"issue":"3","key":"6976_CR17","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.eururo.2018.02.026","volume":"74","author":"N Kinsella","year":"2018","unstructured":"Kinsella N, Stattin P, Cahill D, Brown C, Bill-Axelson A, Bratt O et al (2018) Factors influencing men\u2019s choice of and adherence to active surveillance for low-risk prostate cancer: a mixed-method systematic review. Eur Urol 74(3):261\u201380. https:\/\/doi.org\/10.1016\/j.eururo.2018.02.026","journal-title":"Eur Urol"},{"key":"6976_CR18","doi-asserted-by":"publisher","unstructured":"Beckmann K, Cahill D, Brown C, Van Hemelrijck M, Kinsella N (2021) Understanding reasons for non-adherence to active surveillance for low-intermediate risk prostate cancer. Transl Androl Urol 10(6):2728\u20132736. https:\/\/doi.org\/10.21037\/tau-20-1254","DOI":"10.21037\/tau-20-1254"},{"key":"6976_CR19","doi-asserted-by":"publisher","unstructured":"O\u2019Brien BC, Harris IB, Beckman TJ, Reed DA, Cook DA (2014) Standards for reporting qualitative research: a synthesis of recommendations. Acad Med 89(9):1245\u20131251.\u00a0https:\/\/doi.org\/10.1097\/ACM.0000000000000388","DOI":"10.1097\/ACM.0000000000000388"},{"key":"6976_CR20","unstructured":"Guba EG Lincoln YS (1994) Competing paradigms in qualitative research. Handbook of qualitative research. Thousand Oaks, CA, US: Sage Publications, Inc;. p. 105\u201317."},{"issue":"6999","key":"6976_CR21","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1136\/bmj.311.6999.251","volume":"311","author":"N Britten","year":"1995","unstructured":"Britten N (1995) Qualitative interviews in medical research. BMJ 311(6999):251\u20133. https:\/\/doi.org\/10.1136\/bmj.311.6999.251","journal-title":"BMJ"},{"key":"6976_CR22","doi-asserted-by":"publisher","unstructured":"Braun V, Clarke V (2006) Using thematic analysis in psychology. Qual Res Psychol 3(2):77\u2013101. https:\/\/doi.org\/10.1191\/1478088706qp063oa","DOI":"10.1191\/1478088706qp063oa"},{"key":"6976_CR23","doi-asserted-by":"publisher","unstructured":"Pessoa ASG, Harper E, Santos I, Gracino MCdS (2019) Using reflexive interviewing to foster deep understanding of research participants\u2019 perspectives. Int J Qual Methods 18:1\u20139. https:\/\/doi.org\/10.1177\/1609406918825026","DOI":"10.1177\/1609406918825026"},{"key":"6976_CR24","doi-asserted-by":"publisher","unstructured":"Malterud K, Siersma VD, Guassora AD (2016) Sample size in qualitative interview studies: guided by information power. Qual Health Res 26(13):1753\u20131760. https:\/\/doi.org\/10.1177\/1049732315617444","DOI":"10.1177\/1049732315617444"},{"issue":"1","key":"6976_CR25","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1007\/s00520-019-04796-z","volume":"28","author":"ER Kirby","year":"2020","unstructured":"Kirby ER, Kenny KE, Broom AF, Oliffe JL, Lewis S, Wyld DK et al (2020) Responses to a cancer diagnosis: a qualitative patient-centred interview study. Support Care Cancer 28(1):229\u201338. https:\/\/doi.org\/10.1007\/s00520-019-04796-z","journal-title":"Support Care Cancer"},{"key":"6976_CR26","doi-asserted-by":"publisher","unstructured":"Alvisi MF, Dordoni P, Rancati T, Avuzzi B, Nicolai N, Badenchini F et al (2020) Supporting patients with untreated prostate cancer on active surveillance: what causes an increase in anxiety during the first 10 months? Front Psychol 11:576459. https:\/\/doi.org\/10.3389\/fpsyg.2020.576459","DOI":"10.3389\/fpsyg.2020.576459"},{"issue":"11","key":"6976_CR27","doi-asserted-by":"publisher","first-page":"2910","DOI":"10.1002\/cncr.11386","volume":"97","author":"AJ Roth","year":"2003","unstructured":"Roth AJ, Rosenfeld B, Kornblith AB, Gibson C, Scher HI, Curley-Smart T et al (2003) The memorial anxiety scale for prostate cancer: validation of a new scale to measure anxiety in men with with prostate cancer. Cancer 97(11):2910\u20138. https:\/\/doi.org\/10.1002\/cncr.11386","journal-title":"Cancer"},{"issue":"31","key":"6976_CR28","doi-asserted-by":"publisher","first-page":"2899","DOI":"10.1200\/JCO.19.00572","volume":"37","author":"NM Tauber","year":"2019","unstructured":"Tauber NM, O\u2019Toole MS, Dinkel A, Galica J, Humphris G, Lebel S et al (2019) Effect of psychological intervention on fear of cancer recurrence: a systematic review and meta-analysis. J Clin Oncol 37(31):2899\u2013915. https:\/\/doi.org\/10.1200\/JCO.19.00572","journal-title":"J Clin Oncol"},{"key":"6976_CR29","doi-asserted-by":"publisher","unstructured":"Howell D, Olsen K (2011) Distress-the 6th vital sign. Curr Oncol 18(5):208\u2013210. https:\/\/doi.org\/10.3747\/co.v18i5.790","DOI":"10.3747\/co.v18i5.790"},{"key":"6976_CR30","doi-asserted-by":"publisher","unstructured":"D\u00f6king S, van Koulil SS, Thewes B, Braamse AMJ, Custers JAE, Prins JB (2021) Combined face-to-face and online cognitive-behavioral therapy for high distress of colorectal cancer survivors: a case study. Cogn Behav Pract 28(1):107\u2013123. https:\/\/doi.org\/10.1016\/j.cbpra.2020.06.008","DOI":"10.1016\/j.cbpra.2020.06.008"},{"key":"6976_CR31","doi-asserted-by":"publisher","unstructured":"Gonzalez BD, Jim HSL, Cessna JM, Small BJ, Sutton SK, Jacobsen PB (2015) Concealment of lung cancer diagnosis: prevalence and correlates. Psycho-oncology 24(12):1774\u20131783. https:\/\/doi.org\/10.1002\/pon.3793","DOI":"10.1002\/pon.3793"},{"issue":"2","key":"6976_CR32","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1097\/00002820-200503000-00003","volume":"28","author":"C Kronenwetter","year":"2005","unstructured":"Kronenwetter C, Weidner G, Pettengill E, Marlin R, Crutchfield L, McCormac P et al (2005) A qualitative analysis of interviews of men with early stage prostate cancer: the Prostate Cancer Lifestyle Trial. Cancer Nurs 28(2):99\u2013107. https:\/\/doi.org\/10.1097\/00002820-200503000-00003","journal-title":"Cancer Nurs"},{"issue":"12","key":"6976_CR33","doi-asserted-by":"publisher","first-page":"1686","DOI":"10.1002\/pon.3781","volume":"24","author":"TA Newby","year":"2015","unstructured":"Newby TA, Graff JN, Ganzini LK, McDonagh MS (2015) Interventions that may reduce depressive symptoms among prostate cancer patients: a systematic review and meta-analysis. Psychooncology 24(12):1686\u201393. https:\/\/doi.org\/10.1002\/pon.3781","journal-title":"Psychooncology"},{"key":"6976_CR34","doi-asserted-by":"publisher","unstructured":"Oliffe JL, Davison BJ, Pickles T, Mr\u00f3z L (2009) The self-management of uncertainty among men undertaking active surveillance for low-risk prostate cancer. Qual Health Res 19(4):432\u2013443. https:\/\/doi.org\/10.1177\/1049732309332692","DOI":"10.1177\/1049732309332692"},{"key":"6976_CR35","doi-asserted-by":"publisher","unstructured":"Williams K, Steptoe A, Wardle J (2013) Is a cancer diagnosis a trigger for health behaviour change? Findings from a prospective, population-based study. Br J Can. 108(11):2407\u20132412. https:\/\/doi.org\/10.1038\/bjc.2013.254","DOI":"10.1038\/bjc.2013.254"},{"key":"6976_CR36","doi-asserted-by":"publisher","unstructured":"Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A et al (2021) Global cancer statistics 2020 GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71(3):209\u2013249. https:\/\/doi.org\/10.3322\/caac.21660","DOI":"10.3322\/caac.21660"},{"key":"6976_CR37","doi-asserted-by":"publisher","unstructured":"Taitt HE (2018) Global trends and prostate cancer a review of incidence detection and mortality as influenced by race ethnicity and geographic location. Am J Mens Health 12(6):1807\u20131823. https:\/\/doi.org\/10.1177\/1557988318798279","DOI":"10.1177\/1557988318798279"},{"key":"6976_CR38","doi-asserted-by":"publisher","unstructured":"Cabaniss DL, Moga DE, Oquendo MA (2015) Rethinking the biopsychosocial formulation. Lancet Psychiatry 2(7):579\u2013581. https:\/\/doi.org\/10.1016\/s2215-0366(15)00180-7","DOI":"10.1016\/s2215-0366(15)00180-7"},{"key":"6976_CR39","volume-title":"Body image care for cancer patients: principles and practice","author":"M Henry","year":"2018","unstructured":"Henry M, Alias A (2018) Body image care for cancer patients: principles and practice. Oxford University Press, Body image and functional loss"},{"key":"6976_CR40","doi-asserted-by":"publisher","unstructured":"Thomas C, Wootten A, Robinson P (2013) The experiences of gay and bisexual men diagnosed with prostate cancer: results from an online focus group. Eur J Cancer Care 22(4):522\u2013529. https:\/\/doi.org\/10.1111\/ecc.12058","DOI":"10.1111\/ecc.12058"},{"key":"6976_CR41","doi-asserted-by":"publisher","unstructured":"Kazer MW, Harden J, Burke M, Sanda MG, Hardy J, Bailey DE et al (2011) The experiences of unpartnered men with prostate cancer: a qualitative analysis. J Cancer Surviv 5(2):132\u2013141. https:\/\/doi.org\/10.1007\/s11764-010-0157-3","DOI":"10.1007\/s11764-010-0157-3"},{"key":"6976_CR42","doi-asserted-by":"publisher","unstructured":"Roberts JK, Pavlakis AE, Richards MP (2021) It\u2019s more complicated than it seems virtual qualitative research in the COVID-19 era. Int J Qual Methods 20:16094069211002960. https:\/\/doi.org\/10.1177\/16094069211002959","DOI":"10.1177\/16094069211002959"},{"key":"6976_CR43","doi-asserted-by":"publisher","unstructured":"Foley G (2021) Video-based online interviews for palliative care research: a new normal in COVID-19? Palliative Medicine 35(3):625\u2013626. https:\/\/doi.org\/10.1177\/0269216321989571","DOI":"10.1177\/0269216321989571"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-022-06976-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-022-06976-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-022-06976-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T11:00:49Z","timestamp":1651057249000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-022-06976-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,19]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["6976"],"URL":"https:\/\/doi.org\/10.1007\/s00520-022-06976-w","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,19]]},"assertion":[{"value":"3 December 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 March 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki. Prospective approval was granted by an NHS Research Ethics Committee (REC Reference: 20\/SC\/0070) and the Health Research Authority.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Written informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Patients signed a written informed consent form regarding publishing their non-identifiable data, including quotes in this article.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}