{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T05:09:23Z","timestamp":1789880963076,"version":"4.0.1"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T00:00:00Z","timestamp":1651968000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T00:00:00Z","timestamp":1651968000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>To date, no studies have assessed climacteric symptoms after hystero-adnexectomy for endometrial, cervical, or ovarian cancer. Thus, this study aimed to compare climacteric symptoms among patients who underwent surgery for these three cancer types.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>In this cross-sectional study, we interviewed patients who were registered at a menopausal outpatient clinic between January 1999 and July 2016 after undergoing total hysterectomy, intrapelvic only or intrapelvic plus para-aortic lymph node dissection, and bilateral adnexectomy performed via laparotomy as a cancer treatment. Climacteric symptoms were assessed using a patient-reported questionnaire covering core domains with five symptoms only at the initial consultation. Each symptom was graded from 0 (no symptoms) to 3 (severe symptoms). We evaluated the frequency of symptom severity according to the time elapsed since surgery and the cancer type.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The numbers of patients with endometrial, ovarian, and cervical cancer were 328, 90, and 107, respectively. Overall, climacteric symptoms were more severe in patients with cervical cancer than in those with endometrial or ovarian cancer; symptom severity decreased with increasing time since surgery. However, symptom severity did not decrease significantly over time in patients with cervical cancer even after\u2009&gt;\u20095\u00a0years had elapsed since surgery.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The climacteric symptoms were less severe in patients with endometrial or ovarian cancer with longer time elapsed since surgery but not in those with cervical cancer. Patients with cervical cancer may require more prompt interventions, including symptomatic treatment and longer follow-up period, than those with endometrial or ovarian cancer.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00520-022-07117-z","type":"journal-article","created":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T04:03:02Z","timestamp":1651982582000},"page":"6785-6793","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Climacteric symptoms in postoperative patients among endometrial cancer, cervical cancer, and ovarian cancer: a cross-sectional study"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3260-6755","authenticated-orcid":false,"given":"Yuko","family":"Horiba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuhiro","family":"Yoshino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megumi","family":"Yokota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Iwata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaru","family":"Mimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Aoki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,5,8]]},"reference":[{"key":"7117_CR1","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1136\/ijgc-2021-002949","volume":"32","author":"R Nitecki","year":"2022","unstructured":"Nitecki R, Fu S, Jorgensen KA et al (2022) Employment disruption among women with gynecologic cancers. Int J Gynecol Cancer 32:69\u201378. https:\/\/doi.org\/10.1136\/ijgc-2021-002949","journal-title":"Int J Gynecol Cancer"},{"key":"7117_CR2","unstructured":"World Health Organization (2021) Cancer today. https:\/\/gco.iarc.fr\/today\/home. Accessed 31 January 2022"},{"key":"7117_CR3","unstructured":"Roser M, Cancer RH (2019) https:\/\/ourworldindata.org\/cancer. Accessed 22 June 2020"},{"key":"7117_CR4","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1093\/jjco\/hyq167","volume":"41","author":"T Matsuda","year":"2011","unstructured":"Matsuda T, Ajiki W, Marugame T, Ioka A, Tsukuma H, Sobue T, Research Group of Population-Based Cancer Registries of Japan (2011) Population-based survival of cancer patients diagnosed between 1993 and 1999 in Japan: a chronological and international comparative study. Jpn J Clin Oncol 41:40\u201351. https:\/\/doi.org\/10.1093\/jjco\/hyq167","journal-title":"Jpn J Clin Oncol"},{"key":"7117_CR5","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.ygyno.2006.08.036","volume":"104","author":"K Hodgkinson","year":"2007","unstructured":"Hodgkinson K, Butow P, Fuchs A et al (2007) Long-term survival from gynecologic cancer: psychosocial outcomes, supportive care needs and positive outcomes. Gynecol Oncol 104:381\u2013389. https:\/\/doi.org\/10.1016\/j.ygyno.2006.08.036","journal-title":"Gynecol Oncol"},{"key":"7117_CR6","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1007\/s00520-019-04849-3","volume":"28","author":"AN Slade","year":"2020","unstructured":"Slade AN, Waters MR, Serrano NA (2020) Long-term sleep disturbance and prescription sleep aid use among cancer survivors in the United States. Support Care Cancer 28:551\u2013560. https:\/\/doi.org\/10.1007\/s00520-019-04849-3","journal-title":"Support Care Cancer"},{"key":"7117_CR7","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1111\/j.1471-6712.2007.00557.x","volume":"22","author":"T Rannestad","year":"2008","unstructured":"Rannestad T, Skjeldestad FE, Platou TF, Hagen B (2008) Quality of life among long-term gynaecological cancer survivors. Scand J Caring Sci 22:472\u2013477. https:\/\/doi.org\/10.1111\/j.1471-6712.2007.00557.x","journal-title":"Scand J Caring Sci"},{"key":"7117_CR8","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1080\/00016340802582041","volume":"88","author":"FE Skjeldestad","year":"2009","unstructured":"Skjeldestad FE, Rannestad T (2009) Urinary incontinence and quality of life in long-term gynecological cancer survivors: a population-based cross-sectional study. Acta Obstet Gynecol Scand 88:192\u2013199. https:\/\/doi.org\/10.1080\/00016340802582041","journal-title":"Acta Obstet Gynecol Scand"},{"key":"7117_CR9","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1007\/s11764-015-0472-9","volume":"10","author":"SN Westin","year":"2016","unstructured":"Westin SN, Sun CC, Tung CS et al (2016) Survivors of gynecologic malignancies: impact of treatment on health and well-being. J Cancer Surviv 10:261\u2013270. https:\/\/doi.org\/10.1007\/s11764-015-0472-9","journal-title":"J Cancer Surviv"},{"key":"7117_CR10","doi-asserted-by":"publisher","first-page":"1577","DOI":"10.1016\/j.mayocp.2016.08.002","volume":"91","author":"WA Rocca","year":"2016","unstructured":"Rocca WA, Gazzuola-Rocca L, Smith CY et al (2016) Accelerated accumulation of multimorbidity after bilateral oophorectomy: a population-based cohort study. Mayo Clin Proc 91:1577\u20131589. https:\/\/doi.org\/10.1016\/j.mayocp.2016.08.002","journal-title":"Mayo Clin Proc"},{"key":"7117_CR11","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1111\/j.1525-1438.2007.01167.x","volume":"18","author":"UA Matulonis","year":"2008","unstructured":"Matulonis UA, Kornblith A, Lee H et al (2008) Long-term adjustment of early-stage ovarian cancer survivors. Int J Gynecol Cancer 18:1183\u20131193. https:\/\/doi.org\/10.1111\/j.1525-1438.2007.01167.x","journal-title":"Int J Gynecol Cancer"},{"key":"7117_CR12","unstructured":"National Cancer Center Japan Cancer information Services 2015. https:\/\/ganjoho.jp\/reg_stat\/index.html. Accessed 26 June 2020"},{"key":"7117_CR13","unstructured":"National Cancer Institute Cancer Stat Facts: ovarian cancer. In: Surveillance, Epidemiology and End Results Program. https:\/\/seer.cancer.gov\/statfacts\/html\/ovary.html. Accessed 16 June 2020"},{"key":"7117_CR14","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/0378-5122(90)90059-f","volume":"12","author":"S Kono","year":"1990","unstructured":"Kono S, Sunagawa Y, Higa H, Sunagawa H (1990) Age of menopause in Japanese women: trends and recent changes. Maturitas 12:43\u201349. https:\/\/doi.org\/10.1016\/0378-5122(90)90059-f","journal-title":"Maturitas"},{"key":"7117_CR15","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/0378-5122(92)90003-m","volume":"14","author":"SM McKinlay","year":"1992","unstructured":"McKinlay SM, Brambilla DJ, Posner JG (1992) The normal menopause transition. Maturitas 14:103\u2013115. https:\/\/doi.org\/10.1016\/0378-5122(92)90003-m","journal-title":"Maturitas"},{"key":"7117_CR16","doi-asserted-by":"publisher","first-page":"4995","DOI":"10.3390\/ijerph16244995","volume":"16","author":"M Stanisz","year":"2019","unstructured":"Stanisz M, Panczyk M, Kurzawa R, Grochans E (2019) The effect of prophylactic adnexectomy on the quality of life and psychosocial functioning of women with the BRCA1\/BRCA2 mutations. Int J Environ Res Public Health 16:4995. https:\/\/doi.org\/10.3390\/ijerph16244995","journal-title":"Int J Environ Res Public Health"},{"key":"7117_CR17","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1002\/cncr.10155","volume":"94","author":"SK Lutgendorf","year":"2002","unstructured":"Lutgendorf SK, Anderson B, Ullrich P et al (2002) Quality of life and mood in women with gynecologic cancer: a one year prospective study. Cancer 94:131\u2013140. https:\/\/doi.org\/10.1002\/cncr.10155","journal-title":"Cancer"},{"key":"7117_CR18","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1006\/gyno.2001.6345","volume":"83","author":"YM Chan","year":"2001","unstructured":"Chan YM, Ngan HY, Li BY et al (2001) A longitudinal study on quality of life after gynecologic cancer treatment. Gynecol Oncol 83:10\u201319. https:\/\/doi.org\/10.1006\/gyno.2001.6345","journal-title":"Gynecol Oncol"},{"key":"7117_CR19","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/j.ygyno.2005.08.023","volume":"100","author":"S Bradley","year":"2006","unstructured":"Bradley S, Rose S, Lutgendorf S, Costanzo E, Anderson B (2006) Quality of life and mental health in cervical and endometrial cancer survivors. Gynecol Oncol 100:479\u2013486. https:\/\/doi.org\/10.1016\/j.ygyno.2005.08.023","journal-title":"Gynecol Oncol"},{"key":"7117_CR20","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1006\/gyno.1999.5644","volume":"76","author":"M Klee","year":"2000","unstructured":"Klee M, Thranov I, Machin D (2000) Life after radiotherapy: the psychological and social effects experienced by women treated for advanced stages of cervical cancer. Gynecol Oncol 76:5\u201313. https:\/\/doi.org\/10.1006\/gyno.1999.5644","journal-title":"Gynecol Oncol"},{"key":"7117_CR21","doi-asserted-by":"publisher","first-page":"2108","DOI":"10.1158\/1055-9965.EPI-12-0740","volume":"21","author":"KE Weaver","year":"2012","unstructured":"Weaver KE, Forsythe LP, Reeve BB et al (2012) Mental and physical health-related quality of life among US cancer survivors: population estimates from the 2010 national health interview survey. Cancer Epidemiol Biomarkers Prev 21:2108\u20132117. https:\/\/doi.org\/10.1158\/1055-9965.EPI-12-0740","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"7117_CR22","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/s00520-019-04872-4","volume":"28","author":"K Roberts","year":"2020","unstructured":"Roberts K, Chong T, Hollands E, Tan J, Mohan GRKA, Cohen PA (2020) Screening for sexual health concerns in survivors of gynecological cancer. Support Care Cancer 28:599\u2013605. https:\/\/doi.org\/10.1007\/s00520-019-04872-4","journal-title":"Support Care Cancer"},{"key":"7117_CR23","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/j.ygyno.2007.09.019","volume":"107","author":"TJ Herzog","year":"2007","unstructured":"Herzog TJ, Wright JD (2007) The impact of cervical cancer on quality of life\u2014the components and means for management. Gynecol Oncol 107:572\u2013577. https:\/\/doi.org\/10.1016\/j.ygyno.2007.09.019","journal-title":"Gynecol Oncol"},{"key":"7117_CR24","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1089\/jwh.2007.0613","volume":"17","author":"HP Greenwald","year":"2008","unstructured":"Greenwald HP, McCorkle R (2008) Sexuality and sexual function in long-term survivors of cervical cancer. J Womens Health (Larchmt) 17:955\u2013963. https:\/\/doi.org\/10.1089\/jwh.2007.0613","journal-title":"J Womens Health (Larchmt)"},{"key":"7117_CR25","doi-asserted-by":"publisher","first-page":"3040","DOI":"10.1210\/jc.2007-0581","volume":"92","author":"RH Fogle","year":"2007","unstructured":"Fogle RH, Stanczyk FZ, Zhang X, Paulson RJ (2007) Ovarian androgen production in postmenopausal women. J Clin Endocrinol Metab 92:3040\u20133043. https:\/\/doi.org\/10.1210\/jc.2007-0581","journal-title":"J Clin Endocrinol Metab"},{"key":"7117_CR26","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1006\/frne.2001.0216","volume":"22","author":"F Labrie","year":"2001","unstructured":"Labrie F, Luu-The V, Labrie C, Simard J (2001) DHEA and its transformation into androgens and estrogens in peripheral target tissues: intracrinology. Front Neuroendocrinol 22:185\u2013212. https:\/\/doi.org\/10.1006\/frne.2001.0216","journal-title":"Front Neuroendocrinol"},{"key":"7117_CR27","doi-asserted-by":"publisher","first-page":"1020","DOI":"10.1210\/jcem-39-6-1020","volume":"39","author":"HL Judd","year":"1974","unstructured":"Judd HL, Judd GE, Lucas WE, Yen SS (1974) Endocrine function of the postmenopausal ovary: concentration of androgens and estrogens in ovarian and peripheral vein blood. J Clin Endocrinol Metab 39:1020\u20131024. https:\/\/doi.org\/10.1210\/jcem-39-6-1020","journal-title":"J Clin Endocrinol Metab"},{"key":"7117_CR28","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1002\/pon.2066","volume":"22","author":"I Juraskova","year":"2013","unstructured":"Juraskova I, Butow P, Bonner C, Robertson R, Sharpe L (2013) Sexual adjustment following early stage cervical and endometrial cancer: prospective controlled multi-centre study. Psychooncology 22:153\u2013159. https:\/\/doi.org\/10.1002\/pon.2066","journal-title":"Psychooncology"},{"key":"7117_CR29","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1210\/jcem-13-6-688","volume":"13","author":"HS Kupperman","year":"1953","unstructured":"Kupperman HS, Blatt MH, Wiesbader H, Filler W (1953) Comparative clinical evaluation of estrogenic preparations by the menopausal and amenorrheal indices. J Clin Endocrinol Metab 13:688\u2013703. https:\/\/doi.org\/10.1210\/jcem-13-6-688","journal-title":"J Clin Endocrinol Metab"},{"key":"7117_CR30","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1097\/GME.0000000000000660","volume":"23","author":"M Yokota","year":"2016","unstructured":"Yokota M, Makita K, Hirasawa A, Iwata T, Aoki D (2016) Symptoms and effects of physical factors in Japanese middle-aged women. Menopause 23:974\u2013983. https:\/\/doi.org\/10.1097\/GME.0000000000000660","journal-title":"Menopause"},{"key":"7117_CR31","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1097\/01.gme.0000119984.87302.30","volume":"11","author":"M Kasuga","year":"2004","unstructured":"Kasuga M, Makita K, Ishitani K et al (2004) Relation between climacteric symptoms and ovarian hypofunction in middle-aged and older Japanese women. Menopause 11:631\u2013638. https:\/\/doi.org\/10.1097\/01.gme.0000119984.87302.30","journal-title":"Menopause"},{"key":"7117_CR32","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/s0378-5122(98)00024-3","volume":"29","author":"E Alder","year":"1998","unstructured":"Alder E (1998) The Blatt-Kupperman menopausal index: a critique. Maturitas 29:19\u201324. https:\/\/doi.org\/10.1016\/s0378-5122(98)00024-3","journal-title":"Maturitas"},{"key":"7117_CR33","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1097\/GME.0000000000001787","volume":"28","author":"S Lensen","year":"2021","unstructured":"Lensen S, Archer D, Bell RJ et al (2021) A core outcome set for vasomotor symptoms associated with menopause: the COMMA (Core Outcomes in Menopause) global initiative. Menopause 28:852\u2013858. https:\/\/doi.org\/10.1097\/GME.0000000000001787","journal-title":"Menopause"},{"key":"7117_CR34","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1016\/j.ecl.2015.05.001","volume":"44","author":"N Santoro","year":"2015","unstructured":"Santoro N, Epperson CN, Mathews SB (2015) Menopausal symptoms and their management. Endocrinol Metab Clin North Am 44:497\u2013515. https:\/\/doi.org\/10.1016\/j.ecl.2015.05.001","journal-title":"Endocrinol Metab Clin North Am"},{"key":"7117_CR35","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1097\/GME.0000000000001788","volume":"28","author":"S Lensen","year":"2021","unstructured":"Lensen S, Bell RJ, Carpenter JS et al (2021) A core outcome set for genitourinary symptoms associated with menopause: the COMMA (Core Outcomes in Menopause) global initiative. Menopause 28:859\u2013866. https:\/\/doi.org\/10.1097\/GME.0000000000001788","journal-title":"Menopause"},{"key":"7117_CR36","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.amjmed.2005.09.031","volume":"118","author":"NF Woods","year":"2005","unstructured":"Woods NF, Mitchell ES (2005) Symptoms during the perimenopause: prevalence, severity, trajectory, and significance in women\u2019s lives. Am J Med 118:14\u201324. https:\/\/doi.org\/10.1016\/j.amjmed.2005.09.031","journal-title":"Am J Med"},{"key":"7117_CR37","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/j.ogc.2018.07.005","volume":"45","author":"NE Avis","year":"2018","unstructured":"Avis NE, Crawford SL, Green R (2018) Vasomotor symptoms across the menopause transition: differences among women. Obstet Gynecol Clin North Am 45:629\u2013640. https:\/\/doi.org\/10.1016\/j.ogc.2018.07.005","journal-title":"Obstet Gynecol Clin North Am"},{"key":"7117_CR38","doi-asserted-by":"publisher","first-page":"87","DOI":"10.4065\/mcp.2009.0413","volume":"85","author":"MB Mac Bride","year":"2010","unstructured":"Mac Bride MB, Rhodes DJ, Shuster LT (2010) Vulvovaginal atrophy. Mayo Clin Proc 85:87\u201394. https:\/\/doi.org\/10.4065\/mcp.2009.0413","journal-title":"Mayo Clin Proc"},{"key":"7117_CR39","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1097\/gme.0b013e31821643d9","volume":"18","author":"GA Plotnikoff","year":"2011","unstructured":"Plotnikoff GA, Watanabe K, Torkelson C, La Valleur J, Radosevich DM (2011) The TU-025 keishibukuryogan clinical trial for hot flash management in postmenopausal women: results and lessons for future research. Menopause 18:886\u2013892. https:\/\/doi.org\/10.1097\/gme.0b013e31821643d9","journal-title":"Menopause"},{"key":"7117_CR40","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.ygyno.2011.10.033","volume":"125","author":"MH Einstein","year":"2012","unstructured":"Einstein MH, Rash JK, Chappell RJ, Swietlik JM, Hollenberg JP, Connor JP (2012) Quality of life in cervical cancer survivors: patient and provider perspectives on common complications of cervical cancer and treatment. Gynecol Oncol 125:163\u2013167. https:\/\/doi.org\/10.1016\/j.ygyno.2011.10.033","journal-title":"Gynecol Oncol"},{"key":"7117_CR41","doi-asserted-by":"publisher","first-page":"708","DOI":"10.1016\/S1701-2163(15)30513-2","volume":"36","author":"FF Teng","year":"2014","unstructured":"Teng FF, Kalloger SE, Brotto L, McAlpine JN (2014) Determinants of quality of life in ovarian cancer survivors: a pilot study. J Obstet Gynaecol Can 36:708\u2013715. https:\/\/doi.org\/10.1016\/S1701-2163(15)30513-2","journal-title":"J Obstet Gynaecol Can"},{"key":"7117_CR42","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1007\/s00520-008-0473-6","volume":"17","author":"BP Lai","year":"2009","unstructured":"Lai BP, Tang CS, Chung TK (2009) Age-specific correlates of quality of life in Chinese women with cervical cancer. Support Care Cancer 17:271\u2013278. https:\/\/doi.org\/10.1007\/s00520-008-0473-6","journal-title":"Support Care Cancer"},{"key":"7117_CR43","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1007\/s11864-018-0582-5","volume":"19","author":"MA Angeles","year":"2018","unstructured":"Angeles MA, Mart\u00ednez-G\u00f3mez C et al (2018) Novel surgical strategies in the treatment of gynecological malignancies. Curr Treat Options Oncol 19:73. https:\/\/doi.org\/10.1007\/s11864-018-0582-5","journal-title":"Curr Treat Options Oncol"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-022-07117-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-022-07117-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-022-07117-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T05:08:51Z","timestamp":1655788131000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-022-07117-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,8]]},"references-count":43,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["7117"],"URL":"https:\/\/doi.org\/10.1007\/s00520-022-07117-z","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,8]]},"assertion":[{"value":"16 December 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 May 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All procedures performed in the studies involving human subjects were in accordance with the ethical standards of the institutional and\/or national research committee and the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study design was approved by the Institutional Review Board at Keio University School of Medicine (approval no. 20140189).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All registered participants provided written informed consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}