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This study applied network analysis to investigate how symptoms of both concepts are interconnected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We used cross-sectional data from hematological cancer survivors. A regularized Gaussian graphical model including symptoms of FoP (FoP-Q) and GAD (GAD-7) was estimated. We investigated (i) the overall network structure and (ii) tested on pre-selected items whether both syndromes could be differentiated based on their worry content (cancer related vs. generalized). For this purpose, we applied a metric named\n                      <jats:italic>bridge expected influence<\/jats:italic>\n                      (BEI). Lower values mean that an item is only weakly connected with the items of the other syndrome, which can be an indication of its distinctive characteristic.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Out of 2001 eligible hematological cancer survivors, 922 (46%) participated. The mean age was 64\u00a0years and 53% were female. The mean partial correlation within each construct (GAD: r\u2009=\u2009.13; FoP: r\u2009=\u2009.07) was greater than between both (r\u2009=\u2009.01). BEI values among items supposed to discriminate between the constructs (e.g.,\n                      <jats:italic>worry about many things within GAD<\/jats:italic>\n                      and\n                      <jats:italic>fear not to endure treatment within FoP)<\/jats:italic>\n                      were among the smallest so our assumptions were confirmed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our findings based on the network analysis support the hypothesis that FoP and GAD are different concepts within oncology. Our exploratory data needs to be validated in future longitudinal studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00520-023-07701-x","type":"journal-article","created":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T23:35:35Z","timestamp":1679960135000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Interconnectivity of fear of progression and generalized anxiety \u2013 Network analysis among a sample of hematological cancer survivors"],"prefix":"10.1007","volume":"31","author":[{"given":"Philipp","family":"G\u00f6bel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Kuba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heide","family":"G\u00f6tze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Mehnert-Theuerkauf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten","family":"Spitzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Hartung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Esser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,3,28]]},"reference":[{"issue":"15","key":"7701_CR1","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.1200\/JCO.2013.52.4611","volume":"32","author":"BL Andersen","year":"2014","unstructured":"Andersen BL et al (2014) Screening, assessment, and care of anxiety and depressive symptoms in adults with cancer: an American Society of Clinical Oncology guideline adaptation. 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