{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T02:19:22Z","timestamp":1787883562968,"version":"build-2784847793"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T00:00:00Z","timestamp":1716422400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T00:00:00Z","timestamp":1716422400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001774","name":"University of Sydney","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001774","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>Sleep quality commonly deteriorates in people receiving chemotherapy for breast cancer (BC). We aimed to determine feasibility and acceptability of telehealth-delivered cognitive behaviour therapy for insomnia (CBT-I) in people with early BC receiving (neo)adjuvant chemotherapy.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Multi-centre, single arm, phase 2 feasibility trial. People with stage I-III BC received 4 sessions of telehealth CBT-I over 8 weeks, during chemotherapy. Participants completed Pittsburgh Sleep Quality Index (PSQI) and other Patient Reported Outcome Measures (PROMs) at baseline, post-program (week 9) and post-chemotherapy (week 24); and an Acceptability Questionnaire at week 9. Primary endpoint was proportion completing 4 sessions of telehealth CBT-I.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>In total, 41 participants were recruited: mean age 51 years (range 31\u201373). All 4 CBT-I sessions were completed by 35 (85%) participants. Acceptability of the program was high and 71% reported \u2018<jats:italic>the program was useful\u2019<\/jats:italic>. There was no significant difference in the number of poor sleepers (PSQI score\u2009\u2265\u20095) at baseline 29\/40 (73%) and week 24 17\/25 (68%); or in the mean PSQI score at baseline (7.43, SD 4.06) and week 24 (7.48, SD 4.41). From baseline to week 24, 7\/25 (28%) participants had a\u2009\u2265\u20093 point improvement in sleep quality on PSQI, and 5\/25 (20%) had a\u2009\u2265\u20093 point deterioration. There was no significant difference in mean PROM scores.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>It is feasible to deliver telehealth CBT-I to people with early BC receiving chemotherapy. Contrary to literature predictions, sleep quality did not deteriorate. Telehealth CBT-I has a potential role in preventing and managing sleep disturbance during chemotherapy.<\/jats:p>\n                <jats:p>Australian New Zealand Clinical Trials Registry (ANZCTR) registration number: ACTRN12620001379909 and date 22\/12\/2020.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00520-024-08554-8","type":"journal-article","created":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T04:01:55Z","timestamp":1716436915000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Telehealth cognitive behaviour therapy for the management of sleep disturbance in women with early breast cancer receiving chemotherapy: a feasibility study"],"prefix":"10.1007","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9684-0247","authenticated-orcid":false,"given":"Emma-Kate","family":"Carson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haryana M.","family":"Dhillon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janette L.","family":"Vardy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly Ferrao","family":"Nunes-Zlotkowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Della-Fiorentina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Parsonson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicia","family":"Roncoloato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonia","family":"Pearson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tristan","family":"Barnes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belinda E.","family":"Kiely","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,23]]},"reference":[{"issue":"5","key":"8554_CR1","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1093\/sleep\/24.5.583","volume":"24","author":"J Savard","year":"2001","unstructured":"Savard J et al (2001) Prevalence, clinical characteristics, and risk factors for insomnia in the context of breast cancer. Sleep 24(5):583\u2013590","journal-title":"Sleep"},{"issue":"31","key":"8554_CR2","doi-asserted-by":"crossref","first-page":"5233","DOI":"10.1200\/JCO.2008.21.6333","volume":"27","author":"J Savard","year":"2009","unstructured":"Savard J et al (2009) Prevalence, natural course, and risk factors of insomnia comorbid with cancer over a 2-month period. J Clin Oncol 27(31):5233\u20135239","journal-title":"J Clin Oncol"},{"key":"8554_CR3","unstructured":"RE C (1990) Sleep disturbances. clinical methods: the history, physical, and laboratory examinations. 3rd edition., ed. H.W. Walker HK, Hurst JW, eds. Boston, Butterworths"},{"issue":"1","key":"8554_CR4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.17241\/smr.2011.2.1.1","volume":"2","author":"MM Ohayon","year":"2011","unstructured":"Ohayon MM (2011) Epidemiological Overview of sleep Disorders in the General Population. Sleep Med Res 2(1):1\u20139","journal-title":"Sleep Med Res"},{"issue":"3","key":"8554_CR5","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1200\/JCO.2001.19.3.895","volume":"19","author":"J Savard","year":"2001","unstructured":"Savard J, Morin CM (2001) Insomnia in the context of cancer: a review of a neglected problem. J Clin Oncol 19(3):895\u2013908","journal-title":"J Clin Oncol"},{"issue":"11","key":"8554_CR6","doi-asserted-by":"crossref","first-page":"722","DOI":"10.3949\/ccjm.80a.12170","volume":"80","author":"S Dahiya","year":"2013","unstructured":"Dahiya S, Ahluwalia MS, Walia HK (2013) Sleep disturbances in cancer patients: underrecognized and undertreated. Clevel Clin J Med 80(11):722\u2013732","journal-title":"Clevel Clin J Med"},{"issue":"2","key":"8554_CR7","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/pon.1412","volume":"18","author":"L Liu","year":"2009","unstructured":"Liu L et al (2009) Pre-treatment symptom cluster in breast cancer patients is associated with worse sleep, fatigue and depression during chemotherapy. Psychooncology 18(2):187\u2013194","journal-title":"Psychooncology"},{"issue":"9","key":"8554_CR8","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1093\/sleep\/32.9.1155","volume":"32","author":"J Savard","year":"2009","unstructured":"Savard J et al (2009) Breast cancer patients have progressively impaired sleep-wake activity rhythms during chemotherapy. Sleep 32(9):1155\u20131160","journal-title":"Sleep"},{"issue":"9","key":"8554_CR9","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/S0277-9536(01)00043-0","volume":"54","author":"JR Davidson","year":"2002","unstructured":"Davidson JR et al (2002) Sleep disturbance in cancer patients. Soc Sci Med 54(9):1309\u20131321","journal-title":"Soc Sci Med"},{"issue":"1","key":"8554_CR10","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1471-2296-13-40","volume":"13","author":"MD Mitchell","year":"2012","unstructured":"Mitchell MD et al (2012) Comparative effectiveness of cognitive behavioral therapy for insomnia: a systematic review. BMC Fam Pract 13(1):40","journal-title":"BMC Fam Pract"},{"key":"8554_CR11","first-page":"1113","volume":"10","author":"SN Garland","year":"2014","unstructured":"Garland SN et al (2014) Sleeping well with cancer: a systematic review of cognitive behavioral therapy for insomnia in cancer patients. Neuropsychiatr Dis Treat 10:1113\u20131124","journal-title":"Neuropsychiatr Dis Treat"},{"issue":"25","key":"8554_CR12","doi-asserted-by":"crossref","first-page":"6083","DOI":"10.1200\/JCO.2005.09.548","volume":"23","author":"J Savard","year":"2005","unstructured":"Savard J et al (2005) Randomized study on the efficacy of cognitive-behavioral therapy for insomnia secondary to breast cancer, part I: Sleep and psychological effects. J Clin Oncol 23(25):6083\u20136096","journal-title":"J Clin Oncol"},{"issue":"4","key":"8554_CR13","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1037\/0022-006X.72.4.653","volume":"72","author":"CH Bastien","year":"2004","unstructured":"Bastien CH et al (2004) Cognitive-behavioral therapy for insomnia: comparison of individual therapy, group therapy, and telephone consultations. J Consult Clin Psychol 72(4):653\u2013659","journal-title":"J Consult Clin Psychol"},{"issue":"5","key":"8554_CR14","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1188\/18.ONF.607-618","volume":"45","author":"MS McCarthy","year":"2018","unstructured":"McCarthy MS et al (2018) Feasibility of a telemedicine-delivered cognitive behavioral therapy for insomnia in rural breast cancer survivors. Oncol Nurs Forum 45(5):607\u2013618","journal-title":"Oncol Nurs Forum"},{"issue":"6","key":"8554_CR15","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1037\/a0026135","volume":"42","author":"GA Brenes","year":"2011","unstructured":"Brenes GA, Ingram CW, Danhauer SC (2011) Benefits and challenges of conducting psychotherapy by telephone. Prof Psychol Res Pr 42(6):543\u2013549","journal-title":"Prof Psychol Res Pr"},{"issue":"2","key":"8554_CR16","doi-asserted-by":"crossref","first-page":"32","DOI":"10.7790\/ejap.v4i2.133","volume":"4","author":"FP Thorndike","year":"2008","unstructured":"Thorndike FP et al (2008) Development and perceived utility and impact of an internet intervention for insomnia. E J Appl Psychol 4(2):32\u201342","journal-title":"E J Appl Psychol"},{"issue":"2","key":"8554_CR17","doi-asserted-by":"crossref","first-page":"e16","DOI":"10.2196\/jmir.1081","volume":"10","author":"LM Ritterband","year":"2008","unstructured":"Ritterband LM et al (2008) Real world use of an Internet intervention for pediatric encopresis. J Med Internet Res 10(2):e16","journal-title":"J Med Internet Res"},{"issue":"2","key":"8554_CR18","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0165-1781(89)90047-4","volume":"28","author":"DJ Buysse","year":"1989","unstructured":"Buysse DJ et al (1989) The pittsburgh sleep quality index: a new instrument for psychiatric practice and research. Psychiatry Res 28(2):193\u2013213","journal-title":"Psychiatry Res"},{"issue":"3","key":"8554_CR19","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/S0022-3999(02)00330-6","volume":"53","author":"J Backhaus","year":"2002","unstructured":"Backhaus J et al (2002) Test-retest reliability and validity of the Pittsburgh Sleep Quality Index in primary insomnia. J Psychosom Res 53(3):737\u2013740","journal-title":"J Psychosom Res"},{"issue":"4","key":"8554_CR20","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1136\/aim.2009.000760","volume":"27","author":"CM Hughes","year":"2009","unstructured":"Hughes CM et al (2009) Acupuncture and reflexology for insomnia: a feasibility study. Acupunct Med 27(4):163\u2013168","journal-title":"Acupunct Med"},{"issue":"3","key":"8554_CR21","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1200\/JCO.1997.15.3.974","volume":"15","author":"MJ Brady","year":"1997","unstructured":"Brady MJ et al (1997) Reliability and validity of the functional assessment of cancer therapy-breast quality-of-life instrument. J Clin Oncol 15(3):974\u2013986","journal-title":"J Clin Oncol"},{"issue":"2","key":"8554_CR22","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0885-3924(96)00274-6","volume":"13","author":"SB Yellen","year":"1997","unstructured":"Yellen SB et al (1997) Measuring fatigue and other anemia-related symptoms with the Functional Assessment of Cancer Therapy (FACT) measurement system. J Pain Symptom Manage 13(2):63\u201374","journal-title":"J Pain Symptom Manage"},{"issue":"1","key":"8554_CR23","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1477-7525-1-29","volume":"1","author":"RP Snaith","year":"2003","unstructured":"Snaith RP (2003) The hospital anxiety and depression scale. Health Qual Life Outcomes 1(1):29","journal-title":"Health Qual Life Outcomes"},{"issue":"2","key":"8554_CR24","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0022-3999(01)00296-3","volume":"52","author":"I Bjelland","year":"2002","unstructured":"Bjelland I et al (2002) The validity of the hospital anxiety and depression scale. An updated literature review. J Psychosom Res 52(2):69\u201377","journal-title":"J Psychosom Res"},{"issue":"2","key":"8554_CR25","first-page":"175","volume":"10","author":"KK Ownby","year":"2019","unstructured":"Ownby KK (2019) Use of the distress thermometer in clinical practice. J Adv Pract Oncol 10(2):175\u2013179","journal-title":"J Adv Pract Oncol"},{"issue":"1","key":"8554_CR26","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1007\/s11670-011-0054-y","volume":"23","author":"LL Tang","year":"2011","unstructured":"Tang LL et al (2011) Validation and reliability of distress thermometer in chinese cancer patients. Chin J Cancer Res 23(1):54\u201358","journal-title":"Chin J Cancer Res"},{"key":"8554_CR27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.invent.2017.03.005","volume":"9","author":"E Dozeman","year":"2017","unstructured":"Dozeman E et al (2017) Guided web-based intervention for insomnia targeting breast cancer patients: Feasibility and effect. Internet Interv 9:1\u20136","journal-title":"Internet Interv"},{"issue":"8","key":"8554_CR28","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1093\/jnci\/djx293","volume":"110","author":"R Zachariae","year":"2018","unstructured":"Zachariae R et al (2018) Internet-delivered cognitive-behavioral therapy for insomnia in breast cancer survivors: a randomized controlled trial. J Natl Cancer Inst 110(8):880\u2013887","journal-title":"J Natl Cancer Inst"},{"key":"8554_CR29","doi-asserted-by":"publisher","unstructured":"Bean HR et al (2022) Light enhanced cognitive behavioral therapy for insomnia and fatigue during chemotherapy for breast cancer: a randomized controlled trial. Sleep 45(3):zsab246. https:\/\/doi.org\/10.1093\/sleep\/zsab246","DOI":"10.1093\/sleep\/zsab246"},{"issue":"1","key":"8554_CR30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0197-2456(89)90015-9","volume":"10","author":"R Simon","year":"1989","unstructured":"Simon R (1989) Optimal two-stage designs for phase II clinical trials. Control Clin Trials 10(1):1\u201310","journal-title":"Control Clin Trials"},{"issue":"9","key":"8554_CR31","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1007\/s00520-014-2204-5","volume":"22","author":"S Ancoli-Israel","year":"2014","unstructured":"Ancoli-Israel S et al (2014) Sleep, fatigue, depression, and circadian activity rhythms in women with breast cancer before and after treatment: a 1-year longitudinal study. Support Care Cancer 22(9):2535\u20132545","journal-title":"Support Care Cancer"},{"issue":"1","key":"8554_CR32","first-page":"35","volume":"24","author":"R Fakih","year":"2018","unstructured":"Fakih R et al (2018) Prevalence and severity of sleep disturbances among patients with early breast cancer. Indian J Palliat Care 24(1):35\u201338","journal-title":"Indian J Palliat Care"},{"issue":"3","key":"8554_CR33","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/15402002.2012.660589","volume":"11","author":"L Liu","year":"2013","unstructured":"Liu L et al (2013) Decreased health-related quality of life in women with breast cancer is associated with poor sleep. Behav Sleep Med 11(3):189\u2013206","journal-title":"Behav Sleep Med"},{"key":"8554_CR34","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.smrv.2015.07.001","volume":"27","author":"JA Johnson","year":"2016","unstructured":"Johnson JA et al (2016) A systematic review and meta-analysis of randomized controlled trials of cognitive behavior therapy for insomnia (CBT-I) in cancer survivors. Sleep Med Rev 27:20\u201328","journal-title":"Sleep Med Rev"},{"issue":"7","key":"8554_CR35","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1002\/pon.1969","volume":"21","author":"LM Ritterband","year":"2012","unstructured":"Ritterband LM et al (2012) Initial evaluation of an Internet intervention to improve the sleep of cancer survivors with insomnia. Psychooncology 21(7):695\u2013705","journal-title":"Psychooncology"},{"issue":"9","key":"8554_CR36","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1002\/pon.1818","volume":"20","author":"J Savard","year":"2011","unstructured":"Savard J et al (2011) Feasibility of a self-help treatment for insomnia comorbid with cancer. Psychooncology 20(9):1013\u20131019","journal-title":"Psychooncology"},{"issue":"8","key":"8554_CR37","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.5665\/sleep.3918","volume":"37","author":"J Savard","year":"2014","unstructured":"Savard J et al (2014) Is a video-based cognitive behavioral therapy for insomnia as efficacious as a professionally administered treatment in breast cancer? Results of a randomized controlled trial. Sleep 37(8):1305\u20131314","journal-title":"Sleep"},{"issue":"10","key":"8554_CR38","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1188\/02.ONF.1431-1441","volume":"29","author":"AM Berger","year":"2002","unstructured":"Berger AM et al (2002) Feasibilty of a sleep intervention during adjuvant breast cancer chemotherapy. Oncol Nurs Forum 29(10):1431\u20131441","journal-title":"Oncol Nurs Forum"},{"issue":"6","key":"8554_CR39","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1002\/pon.1438","volume":"18","author":"AM Berger","year":"2009","unstructured":"Berger AM et al (2009) Behavioral therapy intervention trial to improve sleep quality and cancer-related fatigue. Psychooncology 18(6):634\u2013646","journal-title":"Psychooncology"},{"issue":"3","key":"8554_CR40","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/s41416-018-0154-2","volume":"119","author":"O Palesh","year":"2018","unstructured":"Palesh O et al (2018) Feasibility and acceptability of brief behavioral therapy for cancer-related insomnia: effects on insomnia and circadian rhythm during chemotherapy: a phase II randomised multicentre controlled trial. Br J Cancer 119(3):274\u2013281","journal-title":"Br J Cancer"},{"issue":"1","key":"8554_CR41","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1080\/15402002.2019.1707203","volume":"19","author":"LP Marion","year":"2021","unstructured":"Marion LP, Ivers H, Savard J (2021) Feasibility of a preventive intervention for insomnia in women with breast cancer receiving chemotherapy. Behav Sleep Med 19(1):70\u201382","journal-title":"Behav Sleep Med"},{"issue":"4","key":"8554_CR42","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1007\/s00520-012-1612-7","volume":"21","author":"SD Sanford","year":"2013","unstructured":"Sanford SD et al (2013) Longitudinal prospective assessment of sleep quality: Before, during, and after adjuvant chemotherapy for breast cancer. Support Care Cancer 21(4):959\u2013967","journal-title":"Support Care Cancer"},{"issue":"5","key":"8554_CR43","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/j.bbi.2012.02.001","volume":"26","author":"L Liu","year":"2012","unstructured":"Liu L et al (2012) Fatigue and sleep quality are associated with changes in inflammatory markers in breast cancer patients undergoing chemotherapy. Brain Behav Immun 26(5):706\u2013713","journal-title":"Brain Behav Immun"},{"issue":"3","key":"8554_CR44","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/pon.1756","volume":"20","author":"TA Moore","year":"2011","unstructured":"Moore TA, Berger AM, Dizona P (2011) Sleep aid use during and following breast cancer adjuvant chemotherapy. Psychooncology 20(3):321\u2013325","journal-title":"Psychooncology"},{"key":"8554_CR45","doi-asserted-by":"crossref","first-page":"101208","DOI":"10.1016\/j.smrv.2019.08.002","volume":"48","author":"T van der Zweerde","year":"2019","unstructured":"van der Zweerde T et al (2019) Cognitive behavioral therapy for insomnia: A meta-analysis of long-term effects in controlled studies. Sleep Med Rev 48:101208","journal-title":"Sleep Med Rev"},{"issue":"12","key":"8554_CR46","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1093\/sleep\/32.12.1549","volume":"32","author":"CA Espie","year":"2009","unstructured":"Espie CA (2009) \u201cStepped Care\u201d: A Health Technology Solution for Delivering Cognitive Behavioral Therapy as a First Line Insomnia Treatment. Sleep 32(12):1549\u20131558","journal-title":"Sleep"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-024-08554-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-024-08554-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-024-08554-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T12:13:11Z","timestamp":1718626391000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-024-08554-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,23]]},"references-count":46,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["8554"],"URL":"https:\/\/doi.org\/10.1007\/s00520-024-08554-8","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,23]]},"assertion":[{"value":"15 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 May 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards (Institutional Human Research Ethics Committee protocol number HREC\/14\/CRGH\/23). The study was approved by the Sydney Local Health District \u2013 Concord Zone Health Research Ethics Committee for all sites (CH62\/6\/2020\u2013018), with governance approved at all participating sites.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Informed consent to have de-identified data published was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"Author EC has received speaker honoraria from Eli Lilly. Author BK has received speaker honoraria from Novartis, Eisai, MSD and Gilead, travel support from Novartis, Pfizer and MSD, and honoraria for serving on advisory boards for Novartis and Gilead. Author TB has received travel support from GSK and Novartis. Author HD, JV, CB, KNZ, SDF, SK, AP, FR, and AP declare they have no financial interests. The authors have no relevant non-financial interests to disclose.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"375"}}