{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T04:20:49Z","timestamp":1773030049695,"version":"3.50.1"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T00:00:00Z","timestamp":1739923200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T00:00:00Z","timestamp":1739923200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Scientific Research Project of The Chinese Nursing Association","award":["ZHKYQ202107"],"award-info":[{"award-number":["ZHKYQ202107"]}]},{"name":"Scientific Research Project of The Chinese Nursing Association","award":["ZHKYQ202107"],"award-info":[{"award-number":["ZHKYQ202107"]}]},{"name":"Scientific Research Project of The Chinese Nursing Association","award":["ZHKYQ202107"],"award-info":[{"award-number":["ZHKYQ202107"]}]},{"DOI":"10.13039\/501100004735","name":"Hunan Natural Science Foundation","doi-asserted-by":"crossref","award":["2023JJ40922"],"award-info":[{"award-number":["2023JJ40922"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004735","name":"Hunan Natural Science Foundation","doi-asserted-by":"crossref","award":["2023JJ40922"],"award-info":[{"award-number":["2023JJ40922"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004735","name":"Hunan Natural Science Foundation","doi-asserted-by":"crossref","award":["2023JJ40922"],"award-info":[{"award-number":["2023JJ40922"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"crossref"}]},{"name":"the Research Project of China Hunan Provincial Science and Technology Department","award":["2022ZK4059"],"award-info":[{"award-number":["2022ZK4059"]}]},{"name":"the Research Project of China Hunan Provincial Science and Technology Department","award":["2022ZK4059"],"award-info":[{"award-number":["2022ZK4059"]}]},{"name":"the Research Project of China Hunan Provincial Science and Technology Department","award":["2022ZK4059"],"award-info":[{"award-number":["2022ZK4059"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1007\/s00520-025-09273-4","type":"journal-article","created":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T03:43:55Z","timestamp":1739936635000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Financial toxicity-related factors in patients with nasopharyngeal carfcinoma: a cross-sectional study"],"prefix":"10.1007","volume":"33","author":[{"given":"Qin","family":"Luo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuwen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,2,19]]},"reference":[{"issue":"3","key":"9273_CR1","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","volume":"71","author":"H Sung","year":"2021","unstructured":"Sung H, Ferlay J, Siegel RL et al (2021) Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin 71(3):209\u2013249","journal-title":"CA Cancer J Clin"},{"issue":"10192","key":"9273_CR2","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/S0140-6736(19)30956-0","volume":"394","author":"YP Chen","year":"2019","unstructured":"Chen YP, Chan ATC, Le QT, Blanchard P, Sun Y, Ma J (2019) Nasopharyngeal carcinoma. Lancet 394(10192):64\u201380","journal-title":"Lancet"},{"key":"9273_CR3","doi-asserted-by":"crossref","unstructured":"Zhang YM, Gong GZ, Qiu QT, Han YW, Lu HM, Yin Y (2022) Radiomics for diagnosis and radiotherapy of nasopharyngeal carcinoma.\u00a0Front Oncol 11:767134. Published 2022 Jan 5","DOI":"10.3389\/fonc.2021.767134"},{"key":"9273_CR4","doi-asserted-by":"crossref","unstructured":"Gong L, Kwong DL, Dai W et al (2021) Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma.\u00a0Nat Commun 12(1):1540. Published 2021 Mar 9","DOI":"10.1038\/s41467-021-21795-z"},{"issue":"11","key":"9273_CR5","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1002\/cac2.12218","volume":"41","author":"LL Tang","year":"2021","unstructured":"Tang LL, Chen YP, Chen CB et al (2021) The Chinese society of clinical oncology (CSCO) clinical guidelines for the diagnosis and treatment of nasopharyngeal carcinoma. Cancer Commun (Lond) 41(11):1195\u20131227","journal-title":"Cancer Commun (Lond)"},{"key":"9273_CR6","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.critrevonc.2016.08.017","volume":"107","author":"F De Felice","year":"2016","unstructured":"De Felice F, Musio D, Tombolini V (2016) Osteoradionecrosis and intensity modulated radiation therapy: an overview. Crit Rev Oncol Hematol 107:39\u201343","journal-title":"Crit Rev Oncol Hematol"},{"issue":"19","key":"9273_CR7","doi-asserted-by":"publisher","first-page":"3691","DOI":"10.1002\/cncr.30803","volume":"123","author":"F Caparrotti","year":"2017","unstructured":"Caparrotti F, Huang SH, Lu L, Bratman SV, Ringash J, Bayley A, Cho J, Giuliani M, Kim J, Waldron J, Hansen A, Tong L, Xu W, O\u2019Sullivan B, Wood R, Goldstein D, Hope A (2017) Osteoradionecrosis of the mandible in patients with oropharyngeal carcinoma treated with intensity-modulated radiotherapy. Cancer 123(19):3691\u20133700","journal-title":"Cancer"},{"issue":"7","key":"9273_CR8","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1200\/JCO.20.03237","volume":"39","author":"YP Chen","year":"2021","unstructured":"Chen YP, Ismaila N, Chua MLK et al (2021) Chemotherapy in Combination With Radiotherapy for Definitive-Intent Treatment of Stage II-IVA Nasopharyngeal Carcinoma: CSCO and ASCO Guideline. J Clin Oncol 39(7):840\u2013859","journal-title":"J Clin Oncol"},{"issue":"2","key":"9273_CR9","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1007\/s11764-021-01025-7","volume":"16","author":"MI Fitch","year":"2022","unstructured":"Fitch MI, Sharp L, Hanly P, Longo CJ (2022) Experiencing financial toxicity associated with cancer in publicly funded healthcare systems: a systematic review of qualitative studies. J Cancer Surviv 16(2):314\u2013328","journal-title":"J Cancer Surviv"},{"issue":"5","key":"9273_CR10","doi-asserted-by":"publisher","first-page":"437","DOI":"10.3322\/caac.21730","volume":"72","author":"GL Smith","year":"2022","unstructured":"Smith GL, Banegas MP, Acquati C et al (2022) Navigating financial toxicity in patients with cancer: a multidisciplinary management approach. CA Cancer J Clin 72(5):437\u2013453","journal-title":"CA Cancer J Clin"},{"issue":"2","key":"9273_CR11","doi-asserted-by":"publisher","first-page":"153","DOI":"10.3322\/caac.21443","volume":"68","author":"PM Carrera","year":"2018","unstructured":"Carrera PM, Kantarjian HM, Blinder VS (2018) The financial burden and distress of patients with cancer: understanding and stepping-up action on the financial toxicity of cancer treatment. CA Cancer J Clin 68(2):153\u2013165","journal-title":"CA Cancer J Clin"},{"key":"9273_CR12","doi-asserted-by":"crossref","unstructured":"Kuang Y, Yuan X, Zhu Z, Xing W (2023) Financial toxicity among breast cancer patients: a scoping review of risk factors and outcomes [published online ahead of print, 2023 Jul 11]. Cancer Nurs 10.1097","DOI":"10.1097\/NCC.0000000000001262"},{"issue":"6","key":"9273_CR13","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1377\/hlthaff.2012.1263","volume":"32","author":"S Ramsey","year":"2013","unstructured":"Ramsey S, Blough D, Kirchhoff A et al (2013) Washington State cancer patients found to be at greater risk for bankruptcy than people without a cancer diagnosis. Health Aff (Millwood) 32(6):1143\u20131152","journal-title":"Health Aff (Millwood)"},{"issue":"10","key":"9273_CR14","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.6004\/jnccn.2019.7305","volume":"17","author":"GL Smith","year":"2019","unstructured":"Smith GL, Lopez-Olivo MA, Advani PG et al (2019) Financial burdens of cancer treatment: a systematic review of risk factors and outcomes. J Natl Compr Canc Netw 17(10):1184\u20131192","journal-title":"J Natl Compr Canc Netw"},{"issue":"4","key":"9273_CR15","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1016\/S0360-3016(02)02838-9","volume":"53","author":"FM Fang","year":"2002","unstructured":"Fang FM, Chiu HC, Kuo WR et al (2002) Health-related quality of life for nasopharyngeal carcinoma patients with cancer-free survival after treatment. Int J Radiat Oncol Biol Phys 53(4):959\u2013968","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"10","key":"9273_CR16","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1007\/s00520-023-08048-z","volume":"31","author":"L Lin","year":"2023","unstructured":"Lin L, Chen Q, Lai F, Guo D, Wang J, Tian L (2023) The interaction of financial toxicity and social support on social functioning in post-chemotherapy breast cancer patients: a cross-sectional study. Support Care Cancer 31(10):583","journal-title":"Support Care Cancer"},{"issue":"1","key":"9273_CR17","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1001\/jamaoto.2022.3755","volume":"149","author":"CW Noel","year":"2023","unstructured":"Noel CW, Hueniken K, Forner D, Liu G, Eng L, Hosni A, Hahn E, Irish JC, Gilbert R, Yao CMKL, Monteiro E, O\u2019Sullivan B, Waldron J, Huang SH, Goldstein DP, de Almeida JR (2023) Association of household income at diagnosis with financial toxicity, health utility, and survival in patients with head and neck cancer. JAMA Otolaryngol Head Neck Surg 149(1):63\u201370","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"issue":"7","key":"9273_CR18","doi-asserted-by":"publisher","first-page":"2897","DOI":"10.1111\/jonm.13616","volume":"30","author":"X Chen","year":"2022","unstructured":"Chen X, Tao Z, Tang Y et al (2022) Status and associations of nursing practice environments in intensive care units: A cross-sectional study in China. J Nurs Manag 30(7):2897\u20132905","journal-title":"J Nurs Manag"},{"issue":"20","key":"9273_CR19","doi-asserted-by":"publisher","first-page":"3245","DOI":"10.1002\/cncr.28814","volume":"120","author":"JA Souza","year":"2014","unstructured":"Souza JA, Yap BJ, Hlubocky FJ et al (2014) The development of a financial toxicity patient-reported outcome in cancer: The COST measure. Cancer 120(20):3245\u20133253","journal-title":"Cancer"},{"issue":"8","key":"9273_CR20","first-page":"1118","volume":"38","author":"HH Yu","year":"2017","unstructured":"Yu HH, Bi X, Liu YY (2017) Reliability and validity of the Chinese version on comprehensive scores for financial toxicity based on the patient-reported outcome measures. Chin J Epidemiol 38(8):1118\u20131120","journal-title":"Chin J Epidemiol"},{"issue":"1","key":"9273_CR21","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/0022-3999(87)90103-6","volume":"31","author":"H Feifel","year":"1987","unstructured":"Feifel H, Strack S, Nagy VT (1987) Degree of life-threat and differential use of coping modes. J Psychosom Res 31(1):91\u201399","journal-title":"J Psychosom Res"},{"issue":"1","key":"9273_CR22","first-page":"22","volume":"9","author":"XH Shen","year":"2000","unstructured":"Shen XH, Jiang QJ (2000) Report of 701 cases of medical coping style questionnaire. Chin Behav 9(1):22\u201324","journal-title":"Chin Behav"},{"issue":"3\u20134","key":"9273_CR23","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1207\/s15327752jpa5503&4_17","volume":"55","author":"GD Zimet","year":"1990","unstructured":"Zimet GD, Powell SS, Farley GK, Werkman S, Berkoff KA (1990) Psychometric characteristics of the multidimensional scale of perceived social support. J Pers Assess 55(3\u20134):610\u2013617","journal-title":"J Pers Assess"},{"issue":"12","key":"9273_CR24","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1007\/s00066-022-01936-z","volume":"198","author":"A Fabian","year":"2022","unstructured":"Fabian A, Domschikowski J, Greiner W et al (2022) Financial toxicity in cancer patients treated with radiotherapy in Germany-a cross-sectional study. Strahlenther Onkol 198(12):1053\u20131061","journal-title":"Strahlenther Onkol"},{"issue":"10","key":"9273_CR25","doi-asserted-by":"publisher","first-page":"3062","DOI":"10.1002\/hed.26801","volume":"43","author":"K Baddour","year":"2021","unstructured":"Baddour K, Fadel M, Zhao M et al (2021) The cost of cure: examining objective and subjective financial toxicity in head and neck cancer survivors. Head Neck 43(10):3062\u20133075","journal-title":"Head Neck"},{"key":"9273_CR26","doi-asserted-by":"publisher","first-page":"101890","DOI":"10.1016\/j.ctrv.2019.101890","volume":"79","author":"AWM Lee","year":"2019","unstructured":"Lee AWM, Ng WT, Chan JYW et al (2019) Management of locally recurrent nasopharyngeal carcinoma. Cancer Treat Rev 79:101890","journal-title":"Cancer Treat Rev"},{"issue":"11","key":"9273_CR27","doi-asserted-by":"publisher","first-page":"2043","DOI":"10.1093\/tbm\/ibab091","volume":"11","author":"HR Abrams","year":"2021","unstructured":"Abrams HR, Durbin S, Huang CX et al (2021) Financial toxicity in cancer care: origins, impact, and solutions. Transl Behav Med 11(11):2043\u20132054","journal-title":"Transl Behav Med"},{"issue":"9","key":"9273_CR28","doi-asserted-by":"publisher","first-page":"7159","DOI":"10.1007\/s00520-022-07044-z","volume":"30","author":"A Donkor","year":"2022","unstructured":"Donkor A, Atuwo-Ampoh VD, Yakanu F et al (2022) Financial toxicity of cancer care in low- and middle-income countries: a systematic review and meta-analysis. Support Care Cancer 30(9):7159\u20137190","journal-title":"Support Care Cancer"},{"issue":"2","key":"9273_CR29","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1007\/s10549-020-05632-3","volume":"181","author":"J Jing","year":"2020","unstructured":"Jing J, Feng R, Zhang X, Li M, Gao J (2020) Financial toxicity and its associated patient and cancer factors among women with breast cancer: a single-center analysis of low-middle income region in China. Breast Cancer Res Treat 181(2):435\u2013443","journal-title":"Breast Cancer Res Treat"},{"issue":"7","key":"9273_CR30","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1038\/nrurol.2013.76","volume":"10","author":"MC Smaldone","year":"2013","unstructured":"Smaldone MC, Uzzo RG (2013) The Kubler-Ross model, physician distress, and performance reporting. Nat Rev Urol 10(7):425\u2013428","journal-title":"Nat Rev Urol"},{"issue":"9","key":"9273_CR31","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1093\/abm\/kaab114","volume":"56","author":"GX Ayala","year":"2022","unstructured":"Ayala GX, Chan JCN, Cherrington AL et al (2022) Predictors and effects of participation in peer support: a prospective structural equation modeling analysis. Ann Behav Med 56(9):909\u2013919","journal-title":"Ann Behav Med"},{"issue":"6","key":"9273_CR32","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1177\/03008916221078885","volume":"108","author":"F De Felice","year":"2022","unstructured":"De Felice F, Locati LD, Ronchi S, Thariat J, Orlandi E (2022) Quality of life and financial toxicity after (chemo)radiation therapy in head and neck cancer: are there any sex- or gender-related differences? Tumori 108(6):522\u2013525","journal-title":"Tumori"},{"key":"9273_CR33","doi-asserted-by":"publisher","first-page":"618150","DOI":"10.3389\/fimmu.2021.618150","volume":"12","author":"C Xia","year":"2021","unstructured":"Xia C, Jiang C, Li W et al (2021) A phase ii randomized clinical trial and mechanistic studies using improved probiotics to prevent oral mucositis induced by concurrent radiotherapy and chemotherapy in nasopharyngeal carcinoma. Front Immunol 12:618150","journal-title":"Front Immunol"},{"issue":"2","key":"9273_CR34","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1111\/iwj.13897","volume":"20","author":"KC Fang","year":"2023","unstructured":"Fang KC, Lee CH, Chuang HC et al (2023) Acute radiation dermatitis among patients with nasopharyngeal carcinoma treated with proton beam therapy: prognostic factors and treatment outcomes. Int Wound J 20(2):499\u2013507","journal-title":"Int Wound J"},{"issue":"1","key":"9273_CR35","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1007\/s13187-015-0895-z","volume":"32","author":"JB Hamilton","year":"2017","unstructured":"Hamilton JB, Worthy VC, Moore AD, Best NC, Stewart JM, Song MK (2017) Messages of hope: helping family members to overcome fears and fatalistic attitudes toward cancer. J Cancer Educ 32(1):190\u2013197","journal-title":"J Cancer Educ"},{"issue":"9","key":"9273_CR36","doi-asserted-by":"publisher","first-page":"1955","DOI":"10.1007\/s12094-021-02592-y","volume":"23","author":"C Calderon","year":"2021","unstructured":"Calderon C, Gomez D, Carmona-Bayonas A et al (2021) Social support, coping strategies and sociodemographic factors in women with breast cancer. Clin Transl Oncol 23(9):1955\u20131960","journal-title":"Clin Transl Oncol"},{"issue":"2","key":"9273_CR37","doi-asserted-by":"publisher","first-page":"e28747","DOI":"10.2196\/28747","volume":"24","author":"D Sato","year":"2022","unstructured":"Sato D, Sekizawa Y, Sutoh C et al (2022) Effectiveness of unguided internet-based cognitive behavioral therapy and the three good things exercise for insomnia: 3-arm randomized controlled Trial. J Med Internet Res 24(2):e28747","journal-title":"J Med Internet Res"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-025-09273-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-025-09273-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-025-09273-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T21:27:31Z","timestamp":1741987651000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-025-09273-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,19]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["9273"],"URL":"https:\/\/doi.org\/10.1007\/s00520-025-09273-4","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-4653463\/v1","asserted-by":"object"}]},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,19]]},"assertion":[{"value":"28 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 February 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The experimental protocol was established according to the ethical guidelines of the Helsinki Declaration and was approved by the Human Ethics Committee of Xiangya Hospital. Informed consent was obtained from all subjects (IRB No. 202212288).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent for publication was obtained from all participants.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"201"}}