{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T20:13:33Z","timestamp":1793218413134,"version":"4.5.0"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T00:00:00Z","timestamp":1745625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T00:00:00Z","timestamp":1745625600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Purpose<\/jats:title>\n            <jats:p>Distress is not routinely measured in patients undergoing cancer genetic counseling. We evaluated the use of the National Comprehensive Cancer Network\u00ae (NCCN\u00ae) Distress Thermometer (DT) and Problem List (PL) in an unselected population of individuals presenting to a cancer genetics clinic to determine their utility in assessing distress in this population.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Patients presenting to one cancer genetics clinic between April 2019 and March 2020 were asked to complete the DT and PL (2019 version). New patients aged 18 or older were divided into categories of low (DT score\u2009&lt;\u20094) and high distress (DT score\u2009\u2265\u20094), consistent with NCCN groupings for evaluation of distress. Correlates of distress were explored using Chi-square and <jats:italic>t<\/jats:italic> tests.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Younger age and female sex assigned at birth were associated with reporting high distress. Personal history of cancer was not associated with high distress. Worry, fatigue, and sleep disturbance were the most commonly patient-reported problems.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Findings from this study show that the DT can assist in identifying patients undergoing cancer genetic counseling who are experiencing high distress; however, research to develop a PL more specific to the concerns of the oncology genetic counseling patient population may be considered to better identify relevant patient problems.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00520-025-09473-y","type":"journal-article","created":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T07:05:25Z","timestamp":1745651125000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Use of NCCN distress thermometer in cancer genetics patients"],"prefix":"10.1007","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6186-5348","authenticated-orcid":false,"given":"Aidan M.","family":"Kennedy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0423-4966","authenticated-orcid":false,"given":"Andrea M.","family":"Murad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9775-6327","authenticated-orcid":false,"given":"Erika S.","family":"Koeppe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0232-6069","authenticated-orcid":false,"given":"Michelle B.","family":"Riba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5637-3418","authenticated-orcid":false,"given":"Elena M.","family":"Stoffel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0458-1952","authenticated-orcid":false,"given":"Michelle F.","family":"Jacobs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,26]]},"reference":[{"key":"9473_CR1","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1007\/s10897-017-0072-0","volume":"26","author":"G Cicero","year":"2017","unstructured":"Cicero G, De Luca R, Dorangricchia P et al (2017) Risk perception and psychological distress in genetic counselling for hereditary breast and\/or ovarian cancer. J Genet Couns 26:999\u20131007. https:\/\/doi.org\/10.1007\/s10897-017-0072-0","journal-title":"J Genet Couns"},{"key":"9473_CR2","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.6004\/jnccn.2019.0048","volume":"17","author":"MB Riba","year":"2019","unstructured":"Riba MB, Donovan KA, Andersen B et al (2019) Distress management, version 3.2019, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw 17:1229\u20131249. https:\/\/doi.org\/10.6004\/jnccn.2019.0048","journal-title":"J Natl Compr Canc Netw"},{"key":"9473_CR3","first-page":"175","volume":"10","author":"KK Ownby","year":"2019","unstructured":"Ownby KK (2019) Use of the distress thermometer in clinical practice. J Adv Pract Oncol 10:175\u2013179","journal-title":"J Adv Pract Oncol"},{"key":"9473_CR4","doi-asserted-by":"publisher","first-page":"3204","DOI":"10.1245\/s10434-019-07544-z","volume":"26","author":"CC Ciambella","year":"2019","unstructured":"Ciambella CC, Taneja C, Dizon DS et al (2019) Distress: characterizing what causes the thermometer to shift in patients with newly diagnosed breast cancer attending a multidisciplinary clinic. Ann Surg Oncol 26:3204\u20133209. https:\/\/doi.org\/10.1245\/s10434-019-07544-z","journal-title":"Ann Surg Oncol"},{"key":"9473_CR5","doi-asserted-by":"publisher","first-page":"1927","DOI":"10.1002\/pon.5525","volume":"29","author":"T Cimino","year":"2020","unstructured":"Cimino T, Said K, Safier L et al (2020) Psychosocial distress among oncology patients in the safety net. Psychooncology 29:1927\u20131935. https:\/\/doi.org\/10.1002\/pon.5525","journal-title":"Psychooncology"},{"key":"9473_CR6","doi-asserted-by":"publisher","first-page":"e59417","DOI":"10.1371\/journal.pone.0059417","volume":"8","author":"S Vehling","year":"2013","unstructured":"Vehling S, Oechsle K, Koch U, Mehnert A (2013) Receiving palliative treatment moderates the effect of age and gender on demoralization in patients with cancer. PLoS ONE 8:e59417. https:\/\/doi.org\/10.1371\/journal.pone.0059417","journal-title":"PLoS ONE"},{"key":"9473_CR7","doi-asserted-by":"publisher","first-page":"1080","DOI":"10.1002\/pon.1451","volume":"18","author":"S van Dooren","year":"2009","unstructured":"van Dooren S, Duivenvoorden HJ, Passchier J et al (2009) The Distress Thermometer assessed in women at risk of developing hereditary breast cancer. Psychooncology 18:1080\u20131087. https:\/\/doi.org\/10.1002\/pon.1451","journal-title":"Psychooncology"},{"key":"9473_CR8","doi-asserted-by":"publisher","first-page":"13701","DOI":"10.1002\/cam4.5999","volume":"12","author":"AM Kastner","year":"2023","unstructured":"Kastner AM, Fischer-Jacobs J, Brederecke J et al (2023) Distress, anxiety, and depression in persons with hereditary cancer syndromes: results from a nationwide cross-sectional study in Germany. Cancer Med 12:13701\u201313711. https:\/\/doi.org\/10.1002\/cam4.5999","journal-title":"Cancer Med"},{"key":"9473_CR9","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1002\/pon.3485","volume":"23","author":"W Eijzenga","year":"2014","unstructured":"Eijzenga W, Bleiker EMA, Hahn DEE et al (2014) Psychosocial aspects of hereditary cancer (PAHC) questionnaire: development and testing of a screening questionnaire for use in clinical cancer genetics. Psychooncology 23:862\u2013869. https:\/\/doi.org\/10.1002\/pon.3485","journal-title":"Psychooncology"},{"key":"9473_CR10","unstructured":"Code of Ethics. https:\/\/www.nsgc.org\/POLICY\/Code-of-Ethics-Conflict-of-Interest\/Code-of-Ethics. Accessed 16 Jul 2024"},{"key":"9473_CR11","doi-asserted-by":"publisher","first-page":"96","DOI":"10.6004\/jnccn.2022.0004","volume":"20","author":"KA Donovan","year":"2022","unstructured":"Donovan KA, Handzo G, Corbett C et al (2022) NCCN distress thermometer problem list update. J Natl Compr Canc Netw 20:96\u201398. https:\/\/doi.org\/10.6004\/jnccn.2022.0004","journal-title":"J Natl Compr Canc Netw"},{"key":"9473_CR12","doi-asserted-by":"publisher","first-page":"100626","DOI":"10.1016\/j.ssmph.2020.100626","volume":"11","author":"J Bilodeau","year":"2020","unstructured":"Bilodeau J, Marchand A, Demers A (2020) Psychological distress inequality between employed men and women: a gendered exposure model. SSM - Population Health 11:100626. https:\/\/doi.org\/10.1016\/j.ssmph.2020.100626","journal-title":"SSM - Population Health"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-025-09473-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-025-09473-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-025-09473-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T04:31:55Z","timestamp":1746851515000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-025-09473-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,26]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["9473"],"URL":"https:\/\/doi.org\/10.1007\/s00520-025-09473-y","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,26]]},"assertion":[{"value":"30 July 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This was secondary research for which informed consent is not required, based on meeting Federal Exemption #4, 3rd criteria: HIPAA Exemption. The research involved only information collection and analysis involving the investigator\u2019s use of identifiable health information when that use is regulated under 45 CFR parts 160 and 164, subparts A and E, for the purposes of \u201chealth care operations\u201d or \u201cresearch\u201d as those terms are defined at 45 CFR 164.501.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Dr. Michelle Riba has served on the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines\u00ae) for Distress Management panel since 1998 and has been Chair since 2018. The other authors have no conflicts of interest related to this work.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"423"}}