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Such fertility-related considerations include perceptions of putting reproductive goals \u201con hold\u201d and subsequent effects on romantic relationships, parenthood considerations (i.e., arguments for\/against having children), fertility-related uncertainty, and fertility-related concerns.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>An online cross-sectional survey was completed by of <jats:italic>N<\/jats:italic>\u2009=\u2009190 patients\/survivors of AYA cancer (<jats:italic>M<\/jats:italic>\n              <jats:sub>age<\/jats:sub>\u2009=\u200932.5\u00a0years, 87% female, diagnosed between ages 12\u201339\u00a0years; 65% were without biological children at study participation).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The majority of participants (72%) likely wanted to have children. Among them, 46% felt like their reproductive goals were put on hold due to cancer, causing negative emotions and negative effects on romantic relationships (e.g., pressure). Arguments against parenthood were predominantly <jats:italic>cancer-specific<\/jats:italic> (e.g., concerns\/worries about health risks), but also <jats:italic>generic<\/jats:italic> (e.g., loss of freedom, sustainability). Arguments in favor of having children were almost all <jats:italic>generic<\/jats:italic> (e.g., meaning making). Fertility-related uncertainty caused negative emotions (e.g., sadness, insecurity, anxiety, feeling less human), and was correlated with various fertility-related concerns (<jats:italic>r<\/jats:italic>\u2009=\u2009.3\u2013.7).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Perceptions of putting reproductive goals \u201con hold\u201d can affect well-being and romantic relationships, and fertility-related uncertainty may cause various negative emotions among young cancer patients\/survivors. Arguments against parenthood evolve around cancer-specific concerns, which should be addressed by healthcare providers throughout survivorship. Providers are encouraged to provide patient-specific fertility-related education and psychological support if indicated.\n<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00520-025-09832-9","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T07:16:14Z","timestamp":1754896574000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A life put on hold? Navigating fertility-related considerations after cancer in adolescence and young adulthood (AYA)"],"prefix":"10.1007","volume":"33","author":[{"given":"Taylor M.","family":"Dattilo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leah","family":"Waterman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larry L.","family":"Mullins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicky","family":"Lehmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,11]]},"reference":[{"issue":"6","key":"9832_CR1","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1038\/ncpuro0508","volume":"3","author":"H Magelssen","year":"2006","unstructured":"Magelssen H, Bryd\u00f8y M, Foss\u00e5 SD (2006) The effects of cancer and cancer treatments on male reproductive function. 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