{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T08:49:33Z","timestamp":1790239773772,"version":"4.1.0"},"reference-count":56,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:00:00Z","timestamp":1760140800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:00:00Z","timestamp":1760140800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"This work was supported by Paired Assistance Scientific Research Project by The Affiliated Hospital of Xuzhou Medical University","award":["FXJDBF2024218"],"award-info":[{"award-number":["FXJDBF2024218"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1007\/s00520-025-09992-8","type":"journal-article","created":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T06:22:33Z","timestamp":1760163753000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of relaxation training combined with music-based intervention on anxiety and depression in patients undergoing hematopoietic stem cell transplantation: a quasi-experimental study"],"prefix":"10.1007","volume":"33","author":[{"given":"Huiling","family":"Xia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiulian","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawen","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,10,11]]},"reference":[{"key":"9992_CR1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.11233.1","volume":"6","author":"M Norkin","year":"2017","unstructured":"Norkin M, Wingard JR (2017) Recent advances in hematopoietic stem cell transplantation. F1000Res 6:870. https:\/\/doi.org\/10.12688\/f1000research.11233.1","journal-title":"F1000Res"},{"key":"9992_CR2","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1111\/j.1365-2354.2012.01345.x","volume":"21","author":"S Niederbacher","year":"2012","unstructured":"Niederbacher S, Them C, Pinna A et al (2012) Patients\u2019 quality of life after allogeneic haematopoietic stem cell transplantation: mixed-methods study. Eur J Cancer Care 21:548\u2013559. https:\/\/doi.org\/10.1111\/j.1365-2354.2012.01345.x","journal-title":"Eur J Cancer Care"},{"key":"9992_CR3","doi-asserted-by":"publisher","first-page":"1651","DOI":"10.1038\/bmt.2017.190","volume":"52","author":"K Kuba","year":"2017","unstructured":"Kuba K, Esser P, Mehnert A et al (2017) Depression and anxiety following hematopoietic stem cell transplantation: a prospective population-based study in Germany. Bone Marrow Transplant 52:1651\u20131657. https:\/\/doi.org\/10.1038\/bmt.2017.190","journal-title":"Bone Marrow Transplant"},{"key":"9992_CR4","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1002\/cncr.29149","volume":"121","author":"A El-Jawahri","year":"2015","unstructured":"El-Jawahri A, Traeger L, Kuzmuk K et al (2015) Quality of life and mood of patients and family caregivers during hospitalization for hematopoietic stem cell transplantation. Cancer 121:951\u2013959. https:\/\/doi.org\/10.1002\/cncr.29149","journal-title":"Cancer"},{"key":"9992_CR5","doi-asserted-by":"publisher","first-page":"751","DOI":"10.30773\/pi.2019.07.12","volume":"16","author":"H-J Seo","year":"2019","unstructured":"Seo H-J, Baek Y-G, Cho B-S et al (2019) Anxiety and depression of the patients with hematological malignancies during hospitalization for hematopoietic stem cell transplantation. Psychiatry Investig 16:751\u2013758. https:\/\/doi.org\/10.30773\/pi.2019.07.12","journal-title":"Psychiatry Investig"},{"key":"9992_CR6","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1038\/bmt.2014.179","volume":"49","author":"AM Nelson","year":"2014","unstructured":"Nelson AM, Coe CL, Juckett MB et al (2014) Sleep quality following hematopoietic stem cell transplantation: longitudinal trajectories and biobehavioral correlates. Bone Marrow Transplant 49:1405\u20131411. https:\/\/doi.org\/10.1038\/bmt.2014.179","journal-title":"Bone Marrow Transplant"},{"key":"9992_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2147\/TRRM.S194011","volume":"11","author":"M Tavakoli-Ardakani","year":"2019","unstructured":"Tavakoli-Ardakani M, Beyraghi N, Mirjalili M et al (2019) <p>Effect of pretransplant depression on neutrophil recovery following hematopoietic stem cell transplantation<\/p>. TRRM 11:1\u20139. https:\/\/doi.org\/10.2147\/TRRM.S194011","journal-title":"TRRM"},{"key":"9992_CR8","doi-asserted-by":"publisher","first-page":"496.e1","DOI":"10.1016\/j.jtct.2021.02.029","volume":"27","author":"PC Johnson","year":"2021","unstructured":"Johnson PC, Bhatt S, Reynolds MJ et al (2021) Association between baseline patient-reported outcomes and complications of hematopoietic stem cell transplantation. Transplant Cell Ther 27:496.e1-496.e5. https:\/\/doi.org\/10.1016\/j.jtct.2021.02.029","journal-title":"Transplant Cell Ther"},{"key":"9992_CR9","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.14481","volume":"61","author":"J Tomasi","year":"2024","unstructured":"Tomasi J, Zai CC, Pouget JG et al (2024) Heart rate variability: evaluating a potential biomarker of anxiety disorders. Psychophysiology 61:e14481. https:\/\/doi.org\/10.1111\/psyp.14481","journal-title":"Psychophysiology"},{"key":"9992_CR10","doi-asserted-by":"publisher","first-page":"247054702110003","DOI":"10.1177\/24705470211000338","volume":"5","author":"M Chesnut","year":"2021","unstructured":"Chesnut M, Harati S, Paredes P et al (2021) Stress markers for mental states and biotypes of depression and anxiety: a scoping review and preliminary illustrative analysis. Chronic Stress 5:247054702110003. https:\/\/doi.org\/10.1177\/24705470211000338","journal-title":"Chronic Stress"},{"key":"9992_CR11","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1016\/j.jad.2023.02.150","volume":"330","author":"X Liu","year":"2023","unstructured":"Liu X, Lin W, Huang J et al (2023) Depressive symptoms, anxiety and social stress are associated with diminished cardiovascular reactivity in a psychological treatment-naive population. J Affect Disord 330:346\u2013354. https:\/\/doi.org\/10.1016\/j.jad.2023.02.150","journal-title":"J Affect Disord"},{"key":"9992_CR12","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2017.00213","volume":"8","author":"S Laborde","year":"2017","unstructured":"Laborde S, Mosley E, Thayer JF (2017) Heart rate variability and cardiac vagal tone in psychophysiological research \u2013 recommendations for experiment planning, data analysis, and data reporting. Front Psychol 8:213. https:\/\/doi.org\/10.3389\/fpsyg.2017.00213","journal-title":"Front Psychol"},{"key":"9992_CR13","doi-asserted-by":"publisher","DOI":"10.2174\/1573403X16999201231203854","volume":"17","author":"R Tiwari","year":"2021","unstructured":"Tiwari R, Kumar R, Malik S et al (2021) Analysis of heart rate variability and implication of different factors on heart rate variability. Curr Cardiol Rev 17:e160721189770. https:\/\/doi.org\/10.2174\/1573403X16999201231203854","journal-title":"Curr Cardiol Rev"},{"key":"9992_CR14","doi-asserted-by":"publisher","first-page":"235","DOI":"10.30773\/pi.2017.08.17","volume":"15","author":"H-G Kim","year":"2018","unstructured":"Kim H-G, Cheon E-J, Bai D-S (2018) Stress and heart rate variability: a meta-analysis and review of the literature. Psychiatry Investig 15:235\u2013245. https:\/\/doi.org\/10.30773\/pi.2017.08.17","journal-title":"Psychiatry Investig"},{"key":"9992_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2014\/739650","volume":"2014","author":"D Oliveira Miranda","year":"2014","unstructured":"Oliveira Miranda D, Soares de Lima TA, Ribeiro Azevedo L et al (2014) Proinflammatory cytokines correlate with depression and anxiety in colorectal cancer patients. Biomed Res Int 2014:1\u20135. https:\/\/doi.org\/10.1155\/2014\/739650","journal-title":"Biomed Res Int"},{"key":"9992_CR16","doi-asserted-by":"publisher","first-page":"2819","DOI":"10.2147\/NDT.S322078","volume":"17","author":"S Chen","year":"2021","unstructured":"Chen S, Zhang Y, Yuan Y (2021) The combination of serum BDNF, cortisol and IFN-gamma can assist the diagnosis of major depressive disorder. NDT 17:2819\u20132829. https:\/\/doi.org\/10.2147\/NDT.S322078","journal-title":"NDT"},{"key":"9992_CR17","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1016\/j.jad.2017.08.082","volume":"225","author":"Z Tang","year":"2018","unstructured":"Tang Z, Ye G, Chen X et al (2018) Peripheral proinflammatory cytokines in Chinese patients with generalised anxiety disorder. J Affect Disord 225:593\u2013598. https:\/\/doi.org\/10.1016\/j.jad.2017.08.082","journal-title":"J Affect Disord"},{"key":"9992_CR18","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/j.bbi.2017.01.021","volume":"62","author":"R Hou","year":"2017","unstructured":"Hou R, Garner M, Holmes C et al (2017) Peripheral inflammatory cytokines and immune balance in generalised anxiety disorder: case-controlled study. Brain Behav Immun 62:212\u2013218. https:\/\/doi.org\/10.1016\/j.bbi.2017.01.021","journal-title":"Brain Behav Immun"},{"key":"9992_CR19","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1192\/bjp.bp.108.061960","volume":"195","author":"R Uher","year":"2009","unstructured":"Uher R, Farmer A, Henigsberg N (2009) Adverse reactions to antidepressants. Br J Psychiatry 195:202\u2013210. https:\/\/doi.org\/10.1192\/bjp.bp.108.061960","journal-title":"Br J Psychiatry"},{"key":"9992_CR20","doi-asserted-by":"publisher","first-page":"4562","DOI":"10.1200\/JCO.23.00857","volume":"41","author":"LE Carlson","year":"2023","unstructured":"Carlson LE, Ismaila N, Addington EL (2023) Integrative oncology care of symptoms of anxiety and depression in adults with cancer: society for integrative oncology\u2013ASCO guideline. JCO 41:4562\u20134591. https:\/\/doi.org\/10.1200\/JCO.23.00857","journal-title":"JCO"},{"key":"9992_CR21","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.ejon.2019.09.003","volume":"42","author":"Z Gok Metin","year":"2019","unstructured":"Gok Metin Z, Karadas C, Izgu N et al (2019) Effects of progressive muscle relaxation and mindfulness meditation on fatigue, coping styles, and quality of life in early breast cancer patients: an assessor blinded, three-arm, randomized controlled trial. Eur J Oncol Nurs 42:116\u2013125. https:\/\/doi.org\/10.1016\/j.ejon.2019.09.003","journal-title":"Eur J Oncol Nurs"},{"key":"9992_CR22","doi-asserted-by":"publisher","first-page":"217","DOI":"10.7314\/APJCP.2015.16.1.217","volume":"16","author":"SG Yilmaz","year":"2015","unstructured":"Yilmaz SG, Arslan S, Arslan S (2015) Effects of progressive relaxation exercises on anxiety and comfort of Turkish breast cancer patients receiving chemotherapy. Asian Pac J Cancer Prev 16:217\u2013220. https:\/\/doi.org\/10.7314\/APJCP.2015.16.1.217","journal-title":"Asian Pac J Cancer Prev"},{"key":"9992_CR23","doi-asserted-by":"publisher","first-page":"2237","DOI":"10.7314\/APJCP.2013.14.4.2237","volume":"14","author":"MR Isa","year":"2013","unstructured":"Isa MR, Moy FM, Razack AHA et al (2013) Impact of applied progressive deep muscle relaxation training on the level of depression, anxiety and stress among prostate cancer patients: a quasi-experimental study. Asian Pac J Cancer Prev 14:2237\u20132242. https:\/\/doi.org\/10.7314\/APJCP.2013.14.4.2237","journal-title":"Asian Pac J Cancer Prev"},{"key":"9992_CR24","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1177\/0193945916635573","volume":"38","author":"KJ Kim","year":"2016","unstructured":"Kim KJ, Na YK, Hong HS (2016) Effects of progressive muscle relaxation therapy in colorectal cancer patients. West J Nurs Res 38:959\u2013973. https:\/\/doi.org\/10.1177\/0193945916635573","journal-title":"West J Nurs Res"},{"key":"9992_CR25","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1159\/000289133","volume":"66","author":"M Lekander","year":"1997","unstructured":"Lekander M, F\u00fcrst CJ, Rotstein S (1997) Immune effects of relaxation during chemotherapy for ovarian cancer. Psychother Psychosom 66:185\u2013191. https:\/\/doi.org\/10.1159\/000289133","journal-title":"Psychother Psychosom"},{"key":"9992_CR26","doi-asserted-by":"publisher","unstructured":"Bradt J, Dileo C, Shim M (2013) Music interventions for preoperative anxiety. Cochrane Database of Systematic Reviews 2013:. https:\/\/doi.org\/10.1002\/14651858.cd006908.pub2","DOI":"10.1002\/14651858.cd006908.pub2"},{"key":"9992_CR27","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2023.114750","volume":"458","author":"S Bhandarkar","year":"2024","unstructured":"Bhandarkar S, Salvi BV, Shende P (2024) Current scenario and potential of music therapy in the management of diseases. Behav Brain Res 458:114750. https:\/\/doi.org\/10.1016\/j.bbr.2023.114750","journal-title":"Behav Brain Res"},{"key":"9992_CR28","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1007\/s40618-022-01743-4","volume":"45","author":"I Cellai","year":"2022","unstructured":"Cellai I, Filippi S, Comeglio P et al (2022) Testosterone positively regulates vagina NO-induced relaxation: an experimental study in rats. J Endocrinol Invest 45:1161\u20131172. https:\/\/doi.org\/10.1007\/s40618-022-01743-4","journal-title":"J Endocrinol Invest"},{"key":"9992_CR29","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2022.105682","volume":"138","author":"S Nouri","year":"2022","unstructured":"Nouri S, Biedermann SV, Joue G (2022) Effects of circulating estradiol on physiological, behavioural, and subjective correlates of anxiety: a double-blind, randomized, placebo-controlled trial. Psychoneuroendocrinology 138:105682. https:\/\/doi.org\/10.1016\/j.psyneuen.2022.105682","journal-title":"Psychoneuroendocrinology"},{"issue":"1","key":"9992_CR30","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-023-02606-z","volume":"13","author":"Q Fu","year":"2023","unstructured":"Fu Q, Qiu R, Chen L et al (2023) Music prevents stress-induced depression and anxiety-like behavior in mice. Transl Psychiatry 13(1):317","journal-title":"Transl Psychiatry"},{"key":"9992_CR31","doi-asserted-by":"publisher","first-page":"2723","DOI":"10.1002\/cncr.11842","volume":"98","author":"BR Cassileth","year":"2003","unstructured":"Cassileth BR, Vickers AJ, Magill LA (2003) Music therapy for mood disturbance during hospitalization for autologous stem cell transplantation: a randomized controlled trial. Cancer 98:2723\u20132729. https:\/\/doi.org\/10.1002\/cncr.11842","journal-title":"Cancer"},{"key":"9992_CR32","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1111\/ppc.12578","volume":"57","author":"G\u0130 Geyik","year":"2021","unstructured":"Geyik G\u0130, Do\u011fan S, Ozbek H, Atayoglu AT (2021) The effect of music therapy on the physical and mental parameters of cancer patients during hematopoietic stem cell transplantation. Perspect Psychiatr Care 57:558\u2013564. https:\/\/doi.org\/10.1111\/ppc.12578","journal-title":"Perspect Psychiatr Care"},{"key":"9992_CR33","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1080\/15401383.2018.1486257","volume":"13","author":"AL Verstegen","year":"2018","unstructured":"Verstegen AL, Silverman MJ (2018) Effects of music therapy on mood and pain with patients hospitalized for bone marrow transplantation: a randomized effectiveness pilot study. J Creat Ment Health 13:418\u2013428. https:\/\/doi.org\/10.1080\/15401383.2018.1486257","journal-title":"J Creat Ment Health"},{"key":"9992_CR34","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2022.103847","volume":"298","author":"A Sadeghi","year":"2022","unstructured":"Sadeghi A, Pazhoohan S, Hajihashemi S et al (2022) Anxiety-like behavior induced by allergen is associated with decreased irregularity of breathing pattern in rats. Respir Physiol Neurobiol 298:103847. https:\/\/doi.org\/10.1016\/j.resp.2022.103847","journal-title":"Respir Physiol Neurobiol"},{"key":"9992_CR35","doi-asserted-by":"publisher","unstructured":"Li J, Y X, Y F et al (2021) Effects of progressive muscle relaxation training on anxiety, depression and sleep quality in patients with coronavirus disease. Chin J Clinical Research 34:86\u201390+94. https:\/\/doi.org\/10.13429\/j.cnki.cjcr.2021.01.019","DOI":"10.13429\/j.cnki.cjcr.2021.01.019"},{"key":"9992_CR36","first-page":"4594","volume":"29","author":"H Luan","year":"2015","unstructured":"Luan H, Li L (2015) A qualitative study on the psychological experiences of hematopoietic stem cell transplantation patients during their stay in laminar flow rooms. Nurs Res 29:4594\u20134596","journal-title":"Nurs Res"},{"key":"9992_CR37","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","volume":"166","author":"RL Spitzer","year":"2006","unstructured":"Spitzer RL, Kroenke K, Williams JBW, L\u00f6we B (2006) A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med 166:1092. https:\/\/doi.org\/10.1001\/archinte.166.10.1092","journal-title":"Arch Intern Med"},{"key":"9992_CR38","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1002\/pon.4681","volume":"27","author":"P Esser","year":"2018","unstructured":"Esser P, Hartung TJ, Friedrich M et al (2018) The generalized anxiety disorder screener (GAD-7) and the anxiety module of the hospital and depression scale (HADS-A) as screening tools for generalized anxiety disorder among cancer patients. Psycho-Oncol 27:1509\u20131516. https:\/\/doi.org\/10.1002\/pon.4681","journal-title":"Psycho-Oncol"},{"key":"9992_CR39","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","volume":"16","author":"K Kroenke","year":"2001","unstructured":"Kroenke K, Spitzer RL, Williams JBW (2001) The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med 16:606\u2013613. https:\/\/doi.org\/10.1046\/j.1525-1497.2001.016009606.x","journal-title":"J Gen Intern Med"},{"key":"9992_CR40","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-016-0728-6","volume":"16","author":"A Hinz","year":"2016","unstructured":"Hinz A, Mehnert A, Kocalevent R-D et al (2016) Assessment of depression severity with the PHQ-9 in cancer patients and in the general population. BMC Psychiatry 16:22. https:\/\/doi.org\/10.1186\/s12888-016-0728-6","journal-title":"BMC Psychiatry"},{"key":"9992_CR41","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.9807","volume":"4","author":"J Du","year":"2021","unstructured":"Du J, Yu D, Han X et al (2021) Comparison of allogeneic stem cell transplant and autologous stem cell transplant in refractory or relapsed peripheral T-cell lymphoma. JAMA Netw Open 4:e219807. https:\/\/doi.org\/10.1001\/jamanetworkopen.2021.9807","journal-title":"JAMA Netw Open"},{"key":"9992_CR42","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1007\/s11655-017-2956-0","volume":"24","author":"J Liao","year":"2018","unstructured":"Liao J, Wu Y, Zhao Y et al (2018) Progressive muscle relaxation combined with Chinese medicine five-element music on depression for cancer patients: a randomized controlled trial. Chin J Integr Med 24:343\u2013347. https:\/\/doi.org\/10.1007\/s11655-017-2956-0","journal-title":"Chin J Integr Med"},{"key":"9992_CR43","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0293060","volume":"18","author":"KT Nguyen","year":"2023","unstructured":"Nguyen KT, Hoang HTX, Bui QV et al (2023) Effects of music intervention combined with progressive muscle relaxation on anxiety, depression, stress and quality of life among women with cancer receiving chemotherapy: a pilot randomized controlled trial. PLoS ONE 18:e0293060. https:\/\/doi.org\/10.1371\/journal.pone.0293060","journal-title":"PLoS ONE"},{"key":"9992_CR44","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.janxdis.2006.08.001","volume":"21","author":"A Conrad","year":"2007","unstructured":"Conrad A, Roth WT (2007) Muscle relaxation therapy for anxiety disorders: it works but how? J Anxiety Disord 21:243\u2013264. https:\/\/doi.org\/10.1016\/j.janxdis.2006.08.001","journal-title":"J Anxiety Disord"},{"key":"9992_CR45","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1159\/000112889","volume":"77","author":"S Lolak","year":"2008","unstructured":"Lolak S, Connors GL, Sheridan MJ, Wise TN (2008) Effects of progressive muscle relaxation training on anxiety and depression in patients enrolled in an outpatient pulmonary rehabilitation program. Psychother Psychosom 77:119\u2013125. https:\/\/doi.org\/10.1159\/000112889","journal-title":"Psychother Psychosom"},{"key":"9992_CR46","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.ejon.2014.07.010","volume":"19","author":"K Zhou","year":"2015","unstructured":"Zhou K, Li X, Li J et al (2015) A clinical randomized controlled trial of music therapy and progressive muscle relaxation training in female breast cancer patients after radical mastectomy: results on depression, anxiety and length of hospital stay. Eur J Oncol Nurs 19:54\u201359. https:\/\/doi.org\/10.1016\/j.ejon.2014.07.010","journal-title":"Eur J Oncol Nurs"},{"key":"9992_CR47","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1002\/pon.5004","volume":"28","author":"T Lazor","year":"2019","unstructured":"Lazor T, Pole JD, De Souza C et al (2019) Severity, change over time, and risk factors of anxiety in children with cancer depend on anxiety instrument used. Psycho-Oncol 28:710\u2013717. https:\/\/doi.org\/10.1002\/pon.5004","journal-title":"Psycho-Oncol"},{"key":"9992_CR48","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1111\/apa.13452","volume":"105","author":"L Uggla","year":"2016","unstructured":"Uggla L, Bonde L, Svahn B et al (2016) Music therapy can lower the heart rates of severely sick children. Acta Paediatr 105:1225\u20131230. https:\/\/doi.org\/10.1111\/apa.13452","journal-title":"Acta Paediatr"},{"key":"9992_CR49","doi-asserted-by":"publisher","first-page":"9069","DOI":"10.1073\/pnas.0811949106","volume":"106","author":"LM Pyter","year":"2009","unstructured":"Pyter LM, Pineros V, Galang JA et al (2009) Peripheral tumors induce depressive-like behaviors and cytokine production and alter hypothalamic-pituitary-adrenal axis regulation. Proc Natl Acad Sci USA 106:9069\u20139074. https:\/\/doi.org\/10.1073\/pnas.0811949106","journal-title":"Proc Natl Acad Sci USA"},{"key":"9992_CR50","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.bbi.2023.05.012","volume":"112","author":"AM Nelson","year":"2023","unstructured":"Nelson AM, Erdmann AA, Coe CL et al (2023) Inflammatory cytokines and depression symptoms following hematopoietic cell transplantation. Brain Behav Immun 112:11\u201317. https:\/\/doi.org\/10.1016\/j.bbi.2023.05.012","journal-title":"Brain Behav Immun"},{"key":"9992_CR51","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2012.8","volume":"2","author":"N Vogelzangs","year":"2012","unstructured":"Vogelzangs N, Duivis HE, Beekman ATF et al (2012) Association of depressive disorders, depression characteristics and antidepressant medication with inflammation. Transl Psychiatry 2:e79. https:\/\/doi.org\/10.1038\/tp.2012.8","journal-title":"Transl Psychiatry"},{"key":"9992_CR52","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2016.92","volume":"6","author":"N Vogelzangs","year":"2016","unstructured":"Vogelzangs N, de Jonge P, Smit JH et al (2016) Cytokine production capacity in depression and anxiety. Transl Psychiatry 6:e825. https:\/\/doi.org\/10.1038\/tp.2016.92","journal-title":"Transl Psychiatry"},{"key":"9992_CR53","doi-asserted-by":"publisher","DOI":"10.31083\/j.fbl2705148","volume":"27","author":"M Ream","year":"2022","unstructured":"Ream M, Saez-Clarke E, Taub C (2022) Brief post-surgical stress management reduces pro-inflammatory cytokines in overweight and obese breast cancer patients undergoing primary treatment. Front Biosci (Landmark Ed) 27:148. https:\/\/doi.org\/10.31083\/j.fbl2705148","journal-title":"Front Biosci (Landmark Ed)"},{"key":"9992_CR54","doi-asserted-by":"publisher","DOI":"10.1590\/fst.31722","volume":"42","author":"Y Liu","year":"2022","unstructured":"Liu Y, Liu Z, Wang Y et al (2022) Influence and analysis of Chaihu plus Longgu oyster decoction combined with five-elements music therapy on inflammatory factors and depression in patients with reflux cholangitis after cholangiocarcinoma surgery. Food Sci Technol 42:e31722. https:\/\/doi.org\/10.1590\/fst.31722","journal-title":"Food Sci Technol"},{"key":"9992_CR55","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1536\/ihj.50.95","volume":"50","author":"K Okada","year":"2009","unstructured":"Okada K, Kurita A, Takase B et al (2009) Effects of music therapy on autonomic nervous system activity, incidence of heart failure events, and plasma cytokine and catecholamine levels in elderly patients with cerebrovascular disease and dementia. Int Heart J 50:95\u2013110. https:\/\/doi.org\/10.1536\/ihj.50.95","journal-title":"Int Heart J"},{"key":"9992_CR56","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.euroneuro.2006.06.006","volume":"17","author":"D Munitz-Shenkar","year":"2007","unstructured":"Munitz-Shenkar D, Krulik T, Peretz C et al (2007) Psychological and cytokine changes in children and adolescents undergoing hematopoietic stem cell transplantation. Eur Neuropsychopharmacol 17:58\u201363. https:\/\/doi.org\/10.1016\/j.euroneuro.2006.06.006","journal-title":"Eur Neuropsychopharmacol"}],"updated-by":[{"DOI":"10.1007\/s00520-025-10096-6","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000}}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-025-09992-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-025-09992-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-025-09992-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T04:11:48Z","timestamp":1764130308000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-025-09992-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,11]]},"references-count":56,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["9992"],"URL":"https:\/\/doi.org\/10.1007\/s00520-025-09992-8","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,11]]},"assertion":[{"value":"9 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 October 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 October 2025","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The original version of this article was revised. This statement is missing: Jiulian Yuan and Jiawen Hou made equal contributions to this work as co-first authors.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 November 2025","order":8,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":9,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":10,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s00520-025-10096-6","URL":"https:\/\/doi.org\/10.1007\/s00520-025-10096-6","order":11,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was reviewed and approved by the Ethics Committee of the Affiliated Hospital of Xuzhou Medical University (approval number: XYFY2023-KL403-01). All procedures were conducted in accordance with the Declaration of Helsinki, ICH-GCP guidelines, and other applicable ethical standards and regulations. Written informed consent was obtained from all participants prior to their enrollment in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Written informed consent was signed by all participants.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"N\/A.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"935"}}