{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T17:13:04Z","timestamp":1779297184878,"version":"3.51.4"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Selcuk University"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study aimed to assess the impact of complex decongestive therapy (CDT) on proprioception, balance, light touch sensation, and two-point discrimination (2PD) in patients with lower extremity lymphedema (LLL) post-endometrial and cervical cancers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The study included 72 patients diagnosed with LLL, who were randomly assigned using a block randomization method into two groups: a study group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200936) receiving CDT and a control group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200936) receiving no intervention. Patients were assessed before and after treatment using a digital goniometer for proprioception at 15\u00b0, 45\u00b0, and 60\u00b0 knee flexion angles, a single-leg balance test with eyes open and closed, and a 30-s chair-stand test for balance assessment. Sensation was evaluated using Semmes Weinstein Monofilaments for light touch sensation and an aesthesiometer for 2PD.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Significant improvements were observed in knee flexion at 15\u00b0, 45\u00b0, and 60\u00b0 in the study group compared to the control group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001, and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001, respectively). Although there was no difference between groups in single-leg balance with eyes open (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.074) and closed (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.919), improvements were noted within the study group before and after treatment (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). There was no significant difference between groups in light touch sensation, while the 2PD parameter improved in the study group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.012).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CDT may not fully address sensory deficits in patients with LLL. Balance issues appear to worsen with lymphedema progression regardless of treatment. However, CDT shows promise in improving kinesthesia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Trial Registration<\/jats:title>\n                    <jats:p>This is listed with study ID: NCT06204510.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00520-026-10330-9","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T07:02:39Z","timestamp":1769065359000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The efficacy of complex decongestive therapy in the treatment of lymphedema associated with endometrial and cervical cancer: evaluation of sensation and balance"],"prefix":"10.1007","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0699-3771","authenticated-orcid":false,"given":"Emine","family":"Cihan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cansu Sahbaz","family":"Pirincci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,22]]},"reference":[{"key":"10330_CR1","doi-asserted-by":"publisher","first-page":"e20190074","DOI":"10.1590\/1677-5449.190074","volume":"19","author":"ML Brand\u00e3o","year":"2020","unstructured":"Brand\u00e3o ML et al (2020) Efic\u00e1cia da terapia complexa descongestiva para linfedema nos membros inferiores: revis\u00e3o sistem\u00e1tica. 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