{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T14:33:47Z","timestamp":1781620427840,"version":"3.54.5"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1007\/s00520-026-10368-9","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T06:59:28Z","timestamp":1769410768000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Frailty and neuropathy in chemotherapy patients: moderated mediation roles of fatigue and mindfulness on CIPN, anxiety, and depression"],"prefix":"10.1007","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6602-6655","authenticated-orcid":false,"given":"Yanfei","family":"Jin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwen","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,26]]},"reference":[{"key":"10368_CR1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2022.1812","author":"N Desai","year":"2022","unstructured":"Desai N, Arora N, Gupta A (2022) Chemotherapy-induced peripheral neuropathy. JAMA Intern Med. https:\/\/doi.org\/10.1001\/jamainternmed.2022.1812","journal-title":"JAMA Intern Med"},{"key":"10368_CR2","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminoncol.2021.09.004","author":"S Zhang","year":"2021","unstructured":"Zhang S (2021) Chemotherapy-induced peripheral neuropathy and rehabilitation: a review. Semin Oncol. https:\/\/doi.org\/10.1053\/j.seminoncol.2021.09.004","journal-title":"Semin Oncol"},{"issue":"3","key":"10368_CR3","doi-asserted-by":"publisher","DOI":"10.1016\/j.clgc.2024.102067","volume":"22","author":"Z Orszaghova","year":"2024","unstructured":"Orszaghova Z, Galikova D, Lesko P, Obertov\u00e1 J, Rejlekova K, Sycova-Mila Z et al (2024) Chemotherapy-induced peripheral neuropathy (CIPN) as a predictor of decreased quality of life in testicular germ cell tumor survivors. Clin Genitourin Cancer 22(3):102067. https:\/\/doi.org\/10.1016\/j.clgc.2024.102067","journal-title":"Clin Genitourin Cancer"},{"key":"10368_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.112671","volume":"147","author":"A Desforges","year":"2022","unstructured":"Desforges A, Hebert C, Spence A, Reid B, Dhaibar H, Cruz-Topete D et al (2022) Treatment and diagnosis of chemotherapy-induced peripheral neuropathy: an update. Biomed Pharmacother 147:112671-112671. https:\/\/doi.org\/10.1016\/j.biopha.2022.112671","journal-title":"Biomed Pharmacother"},{"key":"10368_CR5","doi-asserted-by":"publisher","unstructured":"Lee K, Bulls H, Hoogland A, James B, Colon-Echevarria C, Jim H (2024) Chemotherapy-induced peripheral neuropathy (CIPN): a narrative review and proposed theoretical model. Cancers 16. https:\/\/doi.org\/10.3390\/cancers16142571","DOI":"10.3390\/cancers16142571"},{"key":"10368_CR6","doi-asserted-by":"publisher","unstructured":"Zaj\u0105czkowska R, Kocot-K\u0119pska M, Leppert W, Wrzosek A, Mika J and Wordliczek J (2019) Mechanisms of chemotherapy-induced peripheral neuropathy. Int J Mol Sci 20. https:\/\/doi.org\/10.3390\/ijms20061451","DOI":"10.3390\/ijms20061451"},{"key":"10368_CR7","doi-asserted-by":"publisher","unstructured":"Jones K, Wechsler S, Zulewski D, Wood L (2022) Pharmacological and nonpharmacological management of chemotherapy-induced peripheral neuropathy: a scoping review of randomized controlled trials. J Palliat Med. https:\/\/doi.org\/10.1089\/jpm.2021.0512","DOI":"10.1089\/jpm.2021.0512"},{"key":"10368_CR8","doi-asserted-by":"publisher","unstructured":"Chou W, Lai C-C, Hung C-Y, Hsueh S, Yeh K, Lu C et al (2022) Clinical significance of frailty on treatment outcome in nongeriatric patients with head and neck cancer and esophageal cancer undergoing curative-intent concurrent chemoradiotherapy. Cancer Control: J Moffitt Cancer Center 29. https:\/\/doi.org\/10.1177\/10732748211045276","DOI":"10.1177\/10732748211045276"},{"key":"10368_CR9","doi-asserted-by":"publisher","first-page":"102725","DOI":"10.1016\/j.ejon.2024.102725","volume":"74","author":"Y Wang","year":"2024","unstructured":"Wang Y, Zhang Y, Liang X, Liu J, Zhao Y, Su Q (2024) The impact of frailty on chemotherapy intolerance in patients with cervical cancer: a longitudinal study. Eur J Oncol Nurs 74:102725. https:\/\/doi.org\/10.1016\/j.ejon.2024.102725","journal-title":"Eur J Oncol Nurs"},{"key":"10368_CR10","doi-asserted-by":"publisher","unstructured":"Ho Y-W, Chen S-Y, Hung Y-S, Lin S, Chou W (2022) Optimal frailty dimensions for assessing frailty and predicting chemotherapy adverse events in older Taiwanese cancer patients. Front Med 9. https:\/\/doi.org\/10.3389\/fmed.2022.828865","DOI":"10.3389\/fmed.2022.828865"},{"key":"10368_CR11","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1007\/s10549-021-06304-6","volume":"189","author":"IR Kleckner","year":"2021","unstructured":"Kleckner IR, Jusko TA, Culakova E, Chung K, Kleckner AS, Asare M et al (2021) Longitudinal study of inflammatory, behavioral, clinical, and psychosocial risk factors for chemotherapy-induced peripheral neuropathy. Breast Cancer Res Treat 189:521\u2013532. https:\/\/doi.org\/10.1007\/s10549-021-06304-6","journal-title":"Breast Cancer Res Treat"},{"key":"10368_CR12","doi-asserted-by":"publisher","unstructured":"Gilmore N, Mohile S, Lei L, Culakova E, Mohamed M, Magnuson A et al (2020) The longitudinal relationship between immune cell profiles and frailty in patients with breast cancer receiving chemotherapy. Breast Cancer Res BCR 23. https:\/\/doi.org\/10.1186\/s13058-021-01388-w","DOI":"10.1186\/s13058-021-01388-w"},{"issue":"2","key":"10368_CR13","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/j.jpainsymman.2016.12.342","volume":"54","author":"C Miaskowski","year":"2017","unstructured":"Miaskowski C, Mastick J, Paul S, Topp K, Smoot B, Abrams G et al (2017) Chemotherapy-induced neuropathy in cancer survivors. J Pain Symptom Manage 54(2):204\u2013218. https:\/\/doi.org\/10.1016\/j.jpainsymman.2016.12.342","journal-title":"J Pain Symptom Manage"},{"key":"10368_CR14","doi-asserted-by":"publisher","unstructured":"Kastelein A, Mols F, Kervezee L, Chavannes N, Gelderblom H, Neefjes J et al (2025) The impact of chemotherapy and body mass index on cancer\u2010related fatigue in colon cancer patients: a PROFILES\u2010registry study. Cancer Med 14. https:\/\/doi.org\/10.1002\/cam4.70536","DOI":"10.1002\/cam4.70536"},{"key":"10368_CR15","doi-asserted-by":"publisher","DOI":"10.1111\/wvn.12573","author":"H-Y Tsai","year":"2022","unstructured":"Tsai H-Y, Wang C-J, Mizuno M, Muta R, Fetzer S, Lin M-F (2022) Predictors of cancer-related fatigue in women with breast cancer undergoing 21 days of a cyclic chemotherapy. Worldviews Evid Based Nurs. https:\/\/doi.org\/10.1111\/wvn.12573","journal-title":"Worldviews Evid Based Nurs"},{"key":"10368_CR16","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2024.42.16_suppl.11015","author":"J Unger","year":"2024","unstructured":"Unger J, Vaidya R, Fisch M, Jones S, Henry N, Hershman D (2024) Patient-reported fatigue and risk of treatment-related adverse events (AEs) in patients receiving systemic therapy in cancer clinical trials. J Clin Oncol. https:\/\/doi.org\/10.1200\/jco.2024.42.16_suppl.11015","journal-title":"J Clin Oncol"},{"key":"10368_CR17","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kead020","author":"T Thibault","year":"2023","unstructured":"Thibault T, Bourredjem A, Maurier F, Wahl D, Muller G, Auma\u00eetre O et al (2023) The mediating effect of fatigue in impaired quality of life in systemic lupus erythematosus: mediation analysis of the French EQUAL cohort. Rheumatology. https:\/\/doi.org\/10.1093\/rheumatology\/kead020","journal-title":"Rheumatology"},{"key":"10368_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.soncn.2021.151179","volume":"37","author":"A Uslu","year":"2021","unstructured":"Uslu A, Canbolat O (2021) Relationship between frailty and fatigue in older cancer patients. Semin Oncol Nurs 37:151179. https:\/\/doi.org\/10.1016\/j.soncn.2021.151179","journal-title":"Semin Oncol Nurs"},{"key":"10368_CR19","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1186\/s13075-015-0784-1","volume":"17","author":"K Louati","year":"2015","unstructured":"Louati K, Berenbaum F (2015) Fatigue in chronic inflammation - a link to pain pathways. Arthritis Res Ther 17:254. https:\/\/doi.org\/10.1186\/s13075-015-0784-1","journal-title":"Arthritis Res Ther"},{"key":"10368_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2024.102505","volume":"114","author":"N Badaghi","year":"2024","unstructured":"Badaghi N, Buskbjerg C, Kwakkenbos L, Bosman S, Zachariae R, Speckens A (2024) Positive health outcomes of mindfulness-based interventions for cancer patients and survivors: a systematic review and meta-analysis. Clin Psychol Rev 114:102505. https:\/\/doi.org\/10.1016\/j.cpr.2024.102505","journal-title":"Clin Psychol Rev"},{"key":"10368_CR21","doi-asserted-by":"publisher","first-page":"1821","DOI":"10.1002\/pon.6046","volume":"31","author":"K McCloy","year":"2022","unstructured":"McCloy K, Hughes C, Dunwoody L, Marley J, Gracey J (2022) Effects of mindfulness-based interventions on fatigue and psychological wellbeing in women with cancer: a systematic review and meta-analysis of randomised control trials. Psychooncology 31:1821\u20131834. https:\/\/doi.org\/10.1002\/pon.6046","journal-title":"Psychooncology"},{"key":"10368_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2020.02.017","author":"S Park","year":"2020","unstructured":"Park S, Sato Y, Takita Y, Tamura N, Ninomiya A, Kosugi T et al (2020) Mindfulness-based cognitive therapy for psychological distress, fear of cancer recurrence, fatigue, spiritual wellbeing and quality of life in patients with breast cancer - a randomized control trial. J Pain Symptom Manage. https:\/\/doi.org\/10.1016\/j.jpainsymman.2020.02.017","journal-title":"J Pain Symptom Manage"},{"key":"10368_CR23","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1038\/s41398-020-0696-y","volume":"10","author":"TKS Ng","year":"2020","unstructured":"Ng TKS, Fam J, Feng L, Cheah IK, Tan CT, Nur F et al (2020) Mindfulness improves inflammatory biomarker levels in older adults with mild cognitive impairment: a randomized controlled trial. Transl Psychiatry 10:21. https:\/\/doi.org\/10.1038\/s41398-020-0696-y","journal-title":"Transl Psychiatry"},{"key":"10368_CR24","doi-asserted-by":"publisher","unstructured":"Fazia T, Bubbico F, Nova A, Buizza C, Cela H, Iozzi D et al (2023) Improving stress management, anxiety, and mental well-being in medical students through an online Mindfulness-Based Intervention: a randomized study. Sci Rep 13. https:\/\/doi.org\/10.1038\/s41598-023-35483-z","DOI":"10.1038\/s41598-023-35483-z"},{"key":"10368_CR25","doi-asserted-by":"publisher","first-page":"7005","DOI":"10.1007\/s00520-022-07123-1","volume":"30","author":"F Chiesi","year":"2022","unstructured":"Chiesi F, Vizza D, Valente M, Bruno R, Lau C, Campagna MR et al (2022) Positive personal resources and psychological distress during the COVID-19 pandemic: resilience, optimism, hope, courage, trait mindfulness, and self-efficacy in breast cancer patients and survivors. Support Care Cancer 30:7005\u20137014. https:\/\/doi.org\/10.1007\/s00520-022-07123-1","journal-title":"Support Care Cancer"},{"key":"10368_CR26","volume-title":"Stress, appraisal, and coping","author":"R Lazarus","year":"1984","unstructured":"Lazarus R, Folkman S (1984) Stress, appraisal, and coping. Springer, New York"},{"key":"10368_CR27","doi-asserted-by":"publisher","first-page":"E93","DOI":"10.1097\/ans.0000000000000347","volume":"44","author":"A Mathew","year":"2021","unstructured":"Mathew A, Doorenbos AZ, Vincent C (2021) Symptom management theory: analysis, evaluation, and implications for caring for adults with cancer. ANS Adv Nurs Sci 44:E93-e112. https:\/\/doi.org\/10.1097\/ans.0000000000000347","journal-title":"ANS Adv Nurs Sci"},{"key":"10368_CR28","doi-asserted-by":"publisher","first-page":"M283","DOI":"10.1093\/gerona\/57.5.m283","volume":"57","author":"WM Bortz 2nd","year":"2002","unstructured":"Bortz WM 2nd (2002) A conceptual framework of frailty: a review. J Gerontol A Biol Sci Med Sci 57:M283\u2013M288. https:\/\/doi.org\/10.1093\/gerona\/57.5.m283","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10368_CR29","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1002\/pon.4065","volume":"26","author":"EL Garland","year":"2017","unstructured":"Garland EL, Thielking P, Thomas EA, Coombs M, White S, Lombardi J et al (2017) Linking dispositional mindfulness and positive psychological processes in cancer survivorship: a multivariate path analytic test of the mindfulness-to-meaning theory. Psychooncology 26:686\u2013692. https:\/\/doi.org\/10.1002\/pon.4065","journal-title":"Psychooncology"},{"key":"10368_CR30","doi-asserted-by":"publisher","unstructured":"Maqbali MA, Sinani MA, Naamani ZA, Badi KA, Tanash MA (2020) Prevalence of fatigue in patients with cancer: a systematic review and meta-analysis. J Pain Symptom Manage. https:\/\/doi.org\/10.1016\/j.jpainsymman.2020.07.037","DOI":"10.1016\/j.jpainsymman.2020.07.037"},{"key":"10368_CR31","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1007\/s12603-020-1504-3","volume":"24","author":"F Runzer-Colmenares","year":"2020","unstructured":"Runzer-Colmenares F, Runzer-Colmenares F, Urrunaga-Pastor D, Roca-Moscoso M, Noriega J, Rosas-Carrasco \u00d3 et al (2020) Frailty and vulnerability as predictors of chemotherapy toxicity in older adults: a longitudinal study in Peru. J Nutr Health Aging 24:966\u2013972. https:\/\/doi.org\/10.1007\/s12603-020-1504-3","journal-title":"J Nutr Health Aging"},{"key":"10368_CR32","doi-asserted-by":"publisher","unstructured":"Jiang R, Noble S, Rosenblatt M, Dai W, Ye J, Liu S et al (2024) The brain structure, inflammatory, and genetic mechanisms mediate the association between physical frailty and depression. Nat Commun 15. https:\/\/doi.org\/10.1038\/s41467-024-48827-8","DOI":"10.1038\/s41467-024-48827-8"},{"key":"10368_CR33","doi-asserted-by":"publisher","unstructured":"Xu J, Li Q, Gao Z, Ji P, Ji Q, Song M et al (2025) Impact of cancer-related fatigue on quality of life in patients with cancer: multiple mediating roles of psychological coherence and stigma. BMC Cancer 25. https:\/\/doi.org\/10.1186\/s12885-025-13468-7","DOI":"10.1186\/s12885-025-13468-7"},{"key":"10368_CR34","doi-asserted-by":"publisher","first-page":"110677","DOI":"10.1016\/j.jpsychores.2021.110677","volume":"152","author":"R Roberts","year":"2021","unstructured":"Roberts R, Ledermann K, Garland E (2021) Mindfulness-oriented recovery enhancement improves negative emotion regulation among opioid-treated chronic pain patients by increasing interoceptive awareness. J Psychosom Res 152:110677. https:\/\/doi.org\/10.1016\/j.jpsychores.2021.110677","journal-title":"J Psychosom Res"},{"key":"10368_CR35","doi-asserted-by":"publisher","unstructured":"Bentler P, Chou C-P (1987) Practical issues in structural equation modeling. Sociol Methods Res 16. https:\/\/doi.org\/10.1177\/0049124187016001004","DOI":"10.1177\/0049124187016001004"},{"key":"10368_CR36","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/s41687-020-0180-8","volume":"4","author":"T Mendoza","year":"2020","unstructured":"Mendoza T, Williams L, Shi Q, Wang X, Bamidele O, Woodruff J et al (2020) The Treatment-induced Neuropathy Assessment Scale (TNAS): a psychometric update following qualitative enrichment. J Patient-Rep Outcomes 4:15. https:\/\/doi.org\/10.1186\/s41687-020-0180-8","journal-title":"J Patient-Rep Outcomes"},{"key":"10368_CR37","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.jamda.2009.11.003","volume":"11","author":"RJJ Gobbens","year":"2010","unstructured":"Gobbens RJJ, van Assen MALM, Luijkx KG, Wijnen-Sponselee MT, Schols JMGA (2010) The Tilburg frailty indicator: psychometric properties. J Am Med Dir Assoc 11:344\u2013355. https:\/\/doi.org\/10.1016\/j.jamda.2009.11.003","journal-title":"J Am Med Dir Assoc"},{"key":"10368_CR38","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/s0885-3924(99)00138-4","volume":"19","author":"T Okuyama","year":"2000","unstructured":"Okuyama T, Akechi T, Kugaya A, Okamura H, Shima Y, Maruguchi M et al (2000) Development and validation of the Cancer Fatigue Scale: a brief, three-dimensional, self-rating scale for assessment of fatigue in cancer patients. J Pain Symptom Manage 19:5\u201314. https:\/\/doi.org\/10.1016\/s0885-3924(99)00138-4","journal-title":"J Pain Symptom Manage"},{"key":"10368_CR39","doi-asserted-by":"publisher","first-page":"1543","DOI":"10.1016\/j.paid.2005.11.025","volume":"40","author":"H Walach","year":"2006","unstructured":"Walach H, Buchheld N, Buttenm\u00fcller V, Kleinknecht N, Schmidt S (2006) Measuring mindfulness\u2013the Freiburg Mindfulness Inventory (FMI). Personality Individ Differ 40:1543\u20131555. https:\/\/doi.org\/10.1016\/j.paid.2005.11.025","journal-title":"Personality Individ Differ"},{"key":"10368_CR40","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","volume":"67","author":"AS Zigmond","year":"1983","unstructured":"Zigmond AS, Snaith RP (1983) The Hospital Anxiety And Depression Scale. Acta Psychiatr Scand 67:361\u2013370. https:\/\/doi.org\/10.1111\/j.1600-0447.1983.tb09716.x","journal-title":"Acta Psychiatr Scand"},{"key":"10368_CR41","doi-asserted-by":"publisher","first-page":"879","DOI":"10.3758\/BRM.40.3.879","volume":"40","author":"KJ Preacher","year":"2008","unstructured":"Preacher KJ, Hayes AF (2008) Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. Behav Res Methods 40:879\u2013891. https:\/\/doi.org\/10.3758\/BRM.40.3.879","journal-title":"Behav Res Methods"},{"key":"10368_CR42","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1037\/0022-0167.53.3.372","volume":"53","author":"B Mallinckrodt","year":"2006","unstructured":"Mallinckrodt B, Abraham WT, Wei M, Russell DW (2006) Advances in testing the statistical significance of mediation effects. J Counseling Psychol 53:372\u2013378. https:\/\/doi.org\/10.1037\/0022-0167.53.3.372","journal-title":"J Counseling Psychol"},{"key":"10368_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/10705519909540118","volume":"6","author":"Lt Hu","year":"1999","unstructured":"Hu Lt, Bentler PM (1999) Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives. Struct Equ Model 6:1\u201355. https:\/\/doi.org\/10.1080\/10705519909540118","journal-title":"Struct Equ Model"},{"key":"10368_CR44","doi-asserted-by":"publisher","first-page":"505","DOI":"10.2147\/CIA.S365494","volume":"18","author":"V Goede","year":"2023","unstructured":"Goede V (2023) Frailty and cancer: current perspectives on assessment and monitoring. Clin Interv Aging 18:505\u2013521. https:\/\/doi.org\/10.2147\/CIA.S365494","journal-title":"Clin Interv Aging"},{"key":"10368_CR45","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2020.05.046","author":"D Narasimhulu","year":"2020","unstructured":"Narasimhulu D, McGree M, Weaver A, Jatoi A, LeBrasseur N, Glaser G et al (2020) Frailty is a determinant of suboptimal chemotherapy in women with advanced ovarian cancer. Gynecol Oncol. https:\/\/doi.org\/10.1016\/j.ygyno.2020.05.046","journal-title":"Gynecol Oncol"},{"key":"10368_CR46","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2023-180943","author":"N Coombs","year":"2023","unstructured":"Coombs N, Beamon E, Rusli E, Wujcik D, Galaznik A, Jamy O (2023) Exploring symptom burden, treatment bother, physical function, and quality of life by frailty status in patients with multiple myeloma. Blood. https:\/\/doi.org\/10.1182\/blood-2023-180943","journal-title":"Blood"},{"key":"10368_CR47","doi-asserted-by":"publisher","DOI":"10.1016\/j.anr.2024.04.004","author":"X Chen","year":"2024","unstructured":"Chen X, Zheng R, Xu X, Wang Z, Huang G, Wu R et al (2024) Frailty and health-related quality of life in elderly patients undergoing esophageal cancer surgery: a longitudinal study. Asian Nurs Res. https:\/\/doi.org\/10.1016\/j.anr.2024.04.004","journal-title":"Asian Nurs Res"},{"key":"10368_CR48","doi-asserted-by":"publisher","first-page":"9722","DOI":"10.3390\/curroncol29120763","volume":"29","author":"A Rodr\u00edguez-Gonz\u00e1lez","year":"2022","unstructured":"Rodr\u00edguez-Gonz\u00e1lez A, Velasco-Durantez V, Martin-Abreu C, Cruz-Castellanos P, Hern\u00e1ndez R, Gil-Raga M et al (2022) Fatigue, emotional distress, and illness uncertainty in patients with metastatic cancer: results from the prospective NEOETIC_SEOM study. Curr Oncol 29:9722\u20139732. https:\/\/doi.org\/10.3390\/curroncol29120763","journal-title":"Curr Oncol"},{"key":"10368_CR49","doi-asserted-by":"publisher","unstructured":"Cristian A, Ruiz M (2020) Comparison of function, fatigue, frailty in patients with malignant hematology, pre-bone marrow transplant and solid tumors. Biol Blood Marrow Transplant 26. https:\/\/doi.org\/10.1016\/j.bbmt.2019.12.194","DOI":"10.1016\/j.bbmt.2019.12.194"},{"key":"10368_CR50","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1046\/j.1365-2648.2001.01697.x","volume":"33","author":"M Dodd","year":"2001","unstructured":"Dodd M, Janson S, Facione N, Faucett J, Froelicher ES, Humphreys J et al (2001) Advancing the science of symptom management. J Adv Nurs 33:668\u2013676. https:\/\/doi.org\/10.1046\/j.1365-2648.2001.01697.x","journal-title":"J Adv Nurs"},{"key":"10368_CR51","doi-asserted-by":"publisher","unstructured":"Folkman S, Lazarus RS (1985) If it changes it must be a process: study of emotion and coping during three stages of a college examination. J Pers Soc Psychol 48:150\u2013170.\u00a0https:\/\/doi.org\/10.1037\/0022-3514.48.1.150","DOI":"10.1037\/0022-3514.48.1.150"},{"key":"10368_CR52","doi-asserted-by":"publisher","DOI":"10.61838\/kman.psychnexus.2.2.11","author":"M Shahbazimoghadam","year":"2024","unstructured":"Shahbazimoghadam M, Bahadoran A, Saeidinik H, Talkhabi F, Namjoo A (2024) Enhancing emotional well-being through proactive coping training and mindfulness: a controlled study. KMAN Counsel Psychol Nexus. https:\/\/doi.org\/10.61838\/kman.psychnexus.2.2.11","journal-title":"KMAN Counsel Psychol Nexus"},{"key":"10368_CR53","doi-asserted-by":"publisher","first-page":"104447","DOI":"10.1016\/j.ijnurstu.2023.104447","volume":"140","author":"J Li","year":"2023","unstructured":"Li J, Li C, Puts M, Wu Y-C, Lyu M, Yuan B et al (2023) Effectiveness of mindfulness-based interventions on anxiety, depression, and fatigue in people with lung cancer: a systematic review and meta-analysis. Int J Nurs Stud 140:104447. https:\/\/doi.org\/10.1016\/j.ijnurstu.2023.104447","journal-title":"Int J Nurs Stud"},{"key":"10368_CR54","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1002\/ana.24951","volume":"81","author":"NP Staff","year":"2017","unstructured":"Staff NP, Grisold A, Grisold W, Windebank AJ (2017) Chemotherapy-induced peripheral neuropathy: a current review. Ann Neurol 81:772\u2013781. https:\/\/doi.org\/10.1002\/ana.24951","journal-title":"Ann Neurol"},{"key":"10368_CR55","doi-asserted-by":"publisher","first-page":"529.e1","DOI":"10.1016\/j.jpain.2016.02.001","volume":"17","author":"MP Jensen","year":"2016","unstructured":"Jensen MP, Ehde DM, Day MA (2016) The behavioral activation and inhibition systems: implications for understanding and treating chronic pain. J Pain 17:529.e1-529.e18. https:\/\/doi.org\/10.1016\/j.jpain.2016.02.001","journal-title":"J Pain"},{"key":"10368_CR56","doi-asserted-by":"publisher","first-page":"3390","DOI":"10.1200\/jco.2015.65.0770","volume":"34","author":"M Johannsen","year":"2016","unstructured":"Johannsen M, O\u2019Connor M, O\u2019Toole MS, Jensen AB, H\u00f8jris I, Zachariae R (2016) Efficacy of mindfulness-based cognitive therapy on late post-treatment pain in women treated for primary breast cancer: a randomized controlled trial. J Clin Oncol 34:3390\u20133399. https:\/\/doi.org\/10.1200\/jco.2015.65.0770","journal-title":"J Clin Oncol"},{"key":"10368_CR57","doi-asserted-by":"publisher","unstructured":"Cunha N, Querino RA, Wolkers PCB, Anjos ACYD (2019) Fatigue management experiences from women undergoing chemotherapy: self-care strategies. Esc Anna Nery. https:\/\/doi.org\/10.1590\/2177-9465-ean-2019-0097","DOI":"10.1590\/2177-9465-ean-2019-0097"},{"key":"10368_CR58","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2023.01.008","author":"A Herranz-G\u00f3mez","year":"2023","unstructured":"Herranz-G\u00f3mez A, Cuenca-Mart\u00ednez F, Suso-Mart\u00ed L, Varangot-Reille C, Prades-Monfort M, Calatayud J et al (2023) Effectiveness of therapeutic exercise models on cancer-related fatigue in patients with cancer undergoing chemotherapy: a systematic review and network meta-analysis. Arch Phys Med Rehabil. https:\/\/doi.org\/10.1016\/j.apmr.2023.01.008","journal-title":"Arch Phys Med Rehabil"},{"key":"10368_CR59","doi-asserted-by":"publisher","DOI":"10.51847\/lrpe9pz2wg","author":"E Y\u0131lmazer","year":"2024","unstructured":"Y\u0131lmazer E, Altinok A (2024) Innovating mindfulness-based stress reduction (MBSR) delivery in cancer care: enhancing accessibility and engagement. Clinical Cancer Investigation Journal. https:\/\/doi.org\/10.51847\/lrpe9pz2wg","journal-title":"Clinical Cancer Investigation Journal"},{"key":"10368_CR60","doi-asserted-by":"publisher","DOI":"10.21926\/obm.icm.2401019","author":"A Tseng","year":"2024","unstructured":"Tseng A (2024) Effectiveness of mindfulness-based stress reduction (MBSR) interventions on mindfulness and stress symptoms for cancer patients: a quantitative assessment. OBM Integrative and Complementary Medicine. https:\/\/doi.org\/10.21926\/obm.icm.2401019","journal-title":"OBM Integrative and Complementary Medicine"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-026-10368-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-026-10368-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-026-10368-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T20:03:40Z","timestamp":1771272220000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-026-10368-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,26]]},"references-count":60,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10368"],"URL":"https:\/\/doi.org\/10.1007\/s00520-026-10368-9","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,26]]},"assertion":[{"value":"22 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interest"}}],"article-number":"128"}}