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Descriptive statistics were used to report hospital utilization patterns. Poisson regression explored risk factors for unplanned presentations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Analyses included data from 346 patients; 115 patients (33%) made one\/or more presentations during the first three cycles of chemotherapy. Of 144 unplanned presentations, 74 (51%) were made during cycle 1. Predominant reasons were fever with\/without neutropenia (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200950, 35%) and nausea\/vomiting (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200930, 21%). Fifty-two percent (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200975) of unplanned presentations did not result in hospital admission. Of 346 patients, 70 (20%) had hospital admissions with a median length of stay of 3\u00a0days (IQR 2\u20137). Multivariable analysis identified the following as predictors for unplanned presentations: cancer stage (stage 1 vs stage 4: IRR 2.50, 95% CI, 1.28\u20134.89; P\u2009=\u20090.01) and cancer type (lung cancer vs breast cancer: IRR 2.25, CI, 1.26\u20134.01; P\u2009=\u20090.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Nausea\/vomiting management support may be one area warranting improvement, a frequent reason for unplanned presentations that are potentially preventable. Such support will be most beneficial during the first treatment cycle, when most unplanned presentations occurred. A high proportion of unplanned presentations did not result in hospital admission, indicating an opportunity to manage some of the side effects within primary care or outpatient settings, rather than utilizing emergency department services.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00520-026-10510-7","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T10:08:47Z","timestamp":1773396527000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unplanned hospital presentations in oncology patients receiving chemotherapy: a secondary analysis of a randomized controlled trial to explore opportunities for improving supportive care"],"prefix":"10.1007","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7843-5106","authenticated-orcid":false,"given":"Bora","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chantale","family":"Boustany","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Fethney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judy M.","family":"Simpson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"White","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"issue":"6","key":"10510_CR1","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1016\/S1470-2045(19)30163-9","volume":"20","author":"BE Wilson","year":"2019","unstructured":"Wilson BE, Jacob S, Yap ML, Ferlay J, Bray F, Barton MB (2019) Estimates of global chemotherapy demands and corresponding physician workforce requirements for 2018 and 2040: a population-based study. 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Following the use of this tool, the authors reviewed and edited the content as needed and take full responsibility for the content of the publication.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declaration of generative AI in scientific writing"}},{"value":"The study protocol of the original randomised controlled trial was registered at the Australian and New Zealand Clinical Trials Registry, for the trial \u2018\n                      Evaluating a shared-care pathway intervention to reduce chemotherapy outpatients' unplanned presentations to hospital \u2013 ESCAPI\u2019\n                      , which this secondary analysis was based on (registration number ACTRN12614001113640; registered on 21\/10\/2024:\n                      \n                      ).","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Trial registration"}},{"value":"The authors declare no competing interests.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}],"article-number":"320"}}