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Hand massage is a nonpharmacological method that can relax the patient and help alleviate these problems. This study aimed to examine the effect of hand massage on pain, comfort, and sleep quality in palliative oncology patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>\n                      A randomized, controlled experimental study was conducted with a sample of 76 oncology patients treated in the palliative care clinic of a public hospital. The patients were randomly allocated to the experimental and control groups. The experimental group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200938) received a total of 16 sessions of hand massage, performed twice a day, 2\u00a0days per week for 4\u00a0weeks. The control group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200938) received no intervention. The patients\u2019 pain, sleep quality, and comfort were assessed before and at 1, 2, and 4\u00a0weeks after the start of the intervention using the Visual Analog Scale for pain, the Pittsburg Sleep Quality Index, the General Comfort Questionnaire, and a smart wristband.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Demographic characteristics and pre-intervention pain, sleep quality, and comfort scores showed no statistical differences between the groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). The experimental group reported significantly lower pain intensity and greater comfort than the control group starting from week 2 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). In addition, subjective sleep quality assessed using the PSQI and objective sleep parameters (sleep duration and sleep score) measured by a smart wristband, including objective sleep duration and objective sleep score, were significantly better in the experimental group than in the control group from the first week (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Hand massage is an effective method for reducing pain and increasing sleep quality and comfort in palliative oncology patients.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Clinical trial registration no:<\/jats:bold>\n                      NCT06360614.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00520-026-10558-5","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:35:31Z","timestamp":1773282931000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The effect of hand massage on pain, comfort, and sleep quality in palliative care oncology patients"],"prefix":"10.1007","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4218-6558","authenticated-orcid":false,"given":"Murat","family":"Koc","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6318-3882","authenticated-orcid":false,"given":"Nurdan Yalcin","family":"Atar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,12]]},"reference":[{"issue":"3","key":"10558_CR1","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3322\/caac.21834","volume":"74","author":"F Bray","year":"2024","unstructured":"Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. 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The study was conducted according to the principles of the Declaration of Helsinki.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"After receiving verbal information about the purpose and procedures of the study, all participants gave verbal and written informed consent.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Patient consent"}},{"value":"No material for which copy permission is required was not used.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Permission to reproduce material from other sources"}},{"value":"The authors declare no competing interests.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"308"}}