{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T15:15:58Z","timestamp":1778685358517,"version":"3.51.4"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:00:00Z","timestamp":1775692800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:00:00Z","timestamp":1775692800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Fujian Provincial Natural Science Foundation Committee","award":["2020J01643"],"award-info":[{"award-number":["2020J01643"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1007\/s00520-026-10649-3","type":"journal-article","created":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T13:38:45Z","timestamp":1775741925000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dynamic changes in symptom clusters and their influencing factors in oral cancer patients throughout the treatment cycle: a longitudinal study based on principal component analysis and linear mixed-effects modeling"],"prefix":"10.1007","volume":"34","author":[{"given":"Jiarou","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yulai","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zijun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,4,9]]},"reference":[{"issue":"12","key":"10649_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.disamonth.2020.100988","volume":"66","author":"G Sarode","year":"2020","unstructured":"Sarode G, Maniyar N, Sarode SC et al (2020) Epidemiologic aspects of oral cancer. Dis-a-Mon 66(12):100988. https:\/\/doi.org\/10.1016\/j.disamonth.2020.100988","journal-title":"Dis-a-Mon"},{"key":"10649_CR2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834","author":"F Bray","year":"2024","unstructured":"Bray F, Laversanne M, Sung H et al (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. https:\/\/doi.org\/10.3322\/caac.21834","journal-title":"CA Cancer J Clin"},{"key":"10649_CR3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2025.01.036","author":"N Zeinali","year":"2025","unstructured":"Zeinali N, Pfannenstiel A, Hallman C et al (2025) Transmission-based monitoring of dual-applicator microwave ablation discriminates discontiguous from contiguous ablation zones in an in vivo porcine liver model. J Vasc Interv Radiol. https:\/\/doi.org\/10.1016\/j.jvir.2025.01.036","journal-title":"J Vasc Interv Radiol"},{"key":"10649_CR4","doi-asserted-by":"publisher","unstructured":"Zeinali N, Sebek J, Fallahi H et al (2022) Electromagnetic transmission coefficient-based assessment of tissue state during Microwave ablation. https:\/\/doi.org\/10.1115\/dmd2022-1037","DOI":"10.1115\/dmd2022-1037"},{"issue":"12","key":"10649_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.disamonth.2020.101036","volume":"66","author":"DB Nandini","year":"2020","unstructured":"Nandini DB, Rao RS, Hosmani J et al (2020) Novel therapies in the management of oral cancer: an update. Dis-a-Mon 66(12):101036. https:\/\/doi.org\/10.1016\/j.disamonth.2020.101036","journal-title":"Dis-a-Mon"},{"issue":"6","key":"10649_CR6","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-023-07770-y","volume":"31","author":"E Fahy","year":"2023","unstructured":"Fahy E, Brooker RC, Fleming JC et al (2023) A review of unplanned admissions in head and neck cancer patients undergoing oncological treatment. Support Care Cancer 31(6):328. https:\/\/doi.org\/10.1007\/s00520-023-07770-y","journal-title":"Support Care Cancer"},{"issue":"4","key":"10649_CR7","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1097\/00002820-200507000-00005","volume":"28","author":"H Kim","year":"2005","unstructured":"Kim H, McGuire DB, Tulman L et al (2005) Symptom clusters: concept analysis and clinical implications for cancer nursing. Cancer Nurs 28(4):270\u2013282. https:\/\/doi.org\/10.1097\/00002820-200507000-00005","journal-title":"Cancer Nurs"},{"issue":"3","key":"10649_CR8","doi-asserted-by":"publisher","DOI":"10.1016\/j.soncn.2023.151407","volume":"39","author":"A Mathew","year":"2023","unstructured":"Mathew A, Lockwood MB, Steffen A et al (2023) Symptom cluster experiences of patients operated for oral cancer: a mixed methods study. Semin Oncol Nurs 39(3):151407. https:\/\/doi.org\/10.1016\/j.soncn.2023.151407","journal-title":"Semin Oncol Nurs"},{"key":"10649_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2022.102263","volume":"62","author":"A Mathew","year":"2023","unstructured":"Mathew A, Tirkey AJ, Pavamani SP et al (2023) On a pathway to resigned acceptance: patients\u2019 experiences of living with symptom clusters in oral cancer. Eur J Oncol Nurs 62:102263. https:\/\/doi.org\/10.1016\/j.ejon.2022.102263","journal-title":"Eur J Oncol Nurs"},{"issue":"4","key":"10649_CR10","volume":"33","author":"Y Zhang","year":"2025","unstructured":"Zhang Y, Yu J, Liu T et al (2025) Core preoperative symptoms and patients\u2019 symptom experiences in oral cancer: a mixed-methods study. Support Care Cancer 33(4):319.10","journal-title":"Support Care Cancer"},{"issue":"8","key":"10649_CR11","doi-asserted-by":"publisher","DOI":"10.1016\/j.apjon.2022.100073","volume":"9","author":"M Ou","year":"2022","unstructured":"Ou M, Wang G, Yan Y et al (2022) Perioperative symptom burden and its influencing factors in patients with oral cancer: a longitudinal study. Asia-Pac J Oncol Nurs 9(8):100073. https:\/\/doi.org\/10.1016\/j.apjon.2022.100073","journal-title":"Asia-Pac J Oncol Nurs"},{"key":"10649_CR12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2020.101819","volume":"48","author":"Y Li","year":"2020","unstructured":"Li Y, Li X, Mao C et al (2020) Symptom clusters in head and neck cancer patients with endotracheal tube: which symptom clusters are independently associated with health-related quality of life? Eur J Oncol Nurs 48:101819. https:\/\/doi.org\/10.1016\/j.ejon.2020.101819","journal-title":"Eur J Oncol Nurs"},{"issue":"4","key":"10649_CR13","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.soncn.2016.09.001","volume":"32","author":"A Barsevick","year":"2016","unstructured":"Barsevick A (2016) Symptom clusters. Semin Oncol Nurs 32(4):333. https:\/\/doi.org\/10.1016\/j.soncn.2016.09.001","journal-title":"Semin Oncol Nurs"},{"issue":"4","key":"10649_CR14","doi-asserted-by":"publisher","first-page":"E17","DOI":"10.1188\/22.ONF.E17-E30","volume":"49","author":"S Chae","year":"2022","unstructured":"Chae S, Cherwin C, Street WN et al (2022) Longitudinal subgrouping of patients with cancer based on symptom experiences: an integrative review. Oncol Nurs Forum 49(4):E17\u2013E30. https:\/\/doi.org\/10.1188\/22.ONF.E17-E30","journal-title":"Oncol Nurs Forum"},{"issue":"1","key":"10649_CR15","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1002\/cam4.4904","volume":"12","author":"Z Zhu","year":"2023","unstructured":"Zhu Z, Sun Y, Kuang Y et al (2023) Contemporaneous symptom networks of multidimensional symptom experiences in cancer survivors: a network analysis. Cancer Med 12(1):663\u2013673. https:\/\/doi.org\/10.1002\/cam4.4904","journal-title":"Cancer Med"},{"key":"10649_CR16","doi-asserted-by":"publisher","DOI":"10.1097\/NCC.0000000000001509","author":"Q Shen","year":"2025","unstructured":"Shen Q, Li J, Fu Z et al (2025) Symptom clusters trajectories and influencing factors in patients with head and neck cancer: a longitudinal study. Cancer Nurs. https:\/\/doi.org\/10.1097\/NCC.0000000000001509","journal-title":"Cancer Nurs"},{"key":"10649_CR17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2023.102282","volume":"63","author":"X Ju","year":"2023","unstructured":"Ju X, Bai J, She Y et al (2023) Symptom cluster trajectories and sentinel symptoms during the first cycle of chemotherapy in patients with lung cancer. Eur J Oncol Nurs 63:102282. https:\/\/doi.org\/10.1016\/j.ejon.2023.102282","journal-title":"Eur J Oncol Nurs"},{"issue":"4","key":"10649_CR18","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1097\/NCC.0000000000001227","volume":"47","author":"H Dunnack Yackel","year":"2024","unstructured":"Dunnack Yackel H, Xu W, Lee JW et al (2024) Symptom patterning across the cancer care trajectory for patients receiving chemoradiation for head and neck cancer: a retrospective longitudinal study using latent transition analysis. Cancer Nurs 47(4):261\u2013270. https:\/\/doi.org\/10.1097\/NCC.0000000000001227","journal-title":"Cancer Nurs"},{"key":"10649_CR19","doi-asserted-by":"publisher","DOI":"10.1590\/1980-265x-tce-2017-0222","author":"GLL Gomes","year":"2019","unstructured":"Gomes GLL, de Oliveira FMRL, Barbosa KTF et al (2019) Theory of unpleasant symptoms: critical analysis. Texto Contexto - Enfermagem. https:\/\/doi.org\/10.1590\/1980-265x-tce-2017-0222","journal-title":"Texto Contexto - Enfermagem"},{"issue":"3 Suppl 2","key":"10649_CR20","first-page":"116","volume":"29","author":"LW Pickle","year":"1992","unstructured":"Pickle LW, Cottler-Fox M (1992) Statistical methods for the analysis of repeated measurements of serum immunoglobulin levels. Semin Hematol 29(3 Suppl 2):116\u2013122","journal-title":"Semin Hematol"},{"key":"10649_CR21","unstructured":"NCSS, LLC (2023) PASS 26.0 Power Analysis and Sample Size Software. Kaysville, Utah, USA"},{"issue":"2","key":"10649_CR22","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.apjon.2021.12.014","volume":"9","author":"W Xiao","year":"2022","unstructured":"Xiao W, Chan CWH, Wang XS et al (2022) Psychometric validation of the Chinese version of the M. D. Anderson symptom inventory\u2014head and neck module in patients with nasopharyngeal carcinoma. Asia-Pac J Oncol Nurs 9(2):113\u2013118. https:\/\/doi.org\/10.1016\/j.apjon.2021.12.014","journal-title":"Asia-Pac J Oncol Nurs"},{"issue":"10","key":"10649_CR23","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1002\/hed.20602","volume":"29","author":"DI Rosenthal","year":"2007","unstructured":"Rosenthal DI, Mendoza TR, Chambers MS et al (2007) Measuring head and neck cancer symptom burden: the development and validation of the M. D. Anderson symptom inventory, head and neck module. Head Neck 29(10):923\u2013931. https:\/\/doi.org\/10.1002\/hed.20602","journal-title":"Head Neck"},{"key":"10649_CR24","doi-asserted-by":"publisher","DOI":"10.1007\/b98835","author":"IT Jolliffe","year":"2002","unstructured":"Jolliffe IT (2002) Principal component analysis. Springer Ser Statist. https:\/\/doi.org\/10.1007\/b98835","journal-title":"Springer Ser Statist"},{"issue":"3","key":"10649_CR25","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1037\/1082-989X.12.3.359","volume":"12","author":"M Linting","year":"2007","unstructured":"Linting M, Meulman JJ, Groenen PJF et al (2007) Stability of nonlinear principal components analysis: an empirical study using the balanced bootstrap. Psychol Methods 12(3):359\u2013379. https:\/\/doi.org\/10.1037\/1082-989X.12.3.359","journal-title":"Psychol Methods"},{"issue":"2","key":"10649_CR26","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1177\/0049124104268644","volume":"33","author":"KP Burnham","year":"2004","unstructured":"Burnham KP, Anderson DR (2004) Multimodel inference: understanding AIC and BIC in model selection. Sociol Methods Res 33(2):261\u2013304. https:\/\/doi.org\/10.1177\/0049124104268644","journal-title":"Sociol Methods Res"},{"issue":"4","key":"10649_CR27","doi-asserted-by":"publisher","DOI":"10.3390\/econometrics9040044","volume":"9","author":"K Ntotsis","year":"2021","unstructured":"Ntotsis K, Karagrigoriou A, Artemiou A (2021) Interdependency pattern recognition in econometrics: a penalized regularization antidote. Econometrics 9(4):44. https:\/\/doi.org\/10.3390\/econometrics9040044","journal-title":"Econometrics"},{"key":"10649_CR28","doi-asserted-by":"publisher","unstructured":"G P, Ramalingam K, Ramani P et al (2024) Longitudinal assessment of the quality of life in oral squamous cell carcinoma patients. Cureus. https:\/\/doi.org\/10.7759\/cureus.60596","DOI":"10.7759\/cureus.60596"},{"issue":"23","key":"10649_CR29","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13236011","volume":"13","author":"CI Misztal","year":"2021","unstructured":"Misztal CI, Green C, Mei C et al (2021) Molecular and cellular mechanisms of perineural invasion in oral squamous cell carcinoma: potential targets for therapeutic intervention. Cancers 13(23):6011. https:\/\/doi.org\/10.3390\/cancers13236011","journal-title":"Cancers"},{"issue":"12","key":"10649_CR30","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10123231","volume":"10","author":"Y Chen","year":"2022","unstructured":"Chen Y, Lin T, Kuo P et al (2022) Psychosocial adjustment changes and related factors in postoperative oral cancer patients: a longitudinal study. Biomedicines 10(12):3231. https:\/\/doi.org\/10.3390\/biomedicines10123231","journal-title":"Biomedicines"},{"issue":"16","key":"10649_CR31","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000037819","volume":"103","author":"KZ Nunes","year":"2024","unstructured":"Nunes KZ, Grippa WR, Lopes AB et al (2024) Cancer symptom clusters, cardiovascular risk, and quality of life of patients with cancer undergoing chemotherapy: a longitudinal pilot study. Medicine 103(16):e37819. https:\/\/doi.org\/10.1097\/md.0000000000037819","journal-title":"Medicine"},{"key":"10649_CR32","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-022-02329-5","author":"Y Ihara","year":"2022","unstructured":"Ihara Y, Kato H, Tashimo Y et al (2022) Changes in oral function, swallowing function, and quality of life in patients with head and neck cancer: a prospective cohort study. BMC Oral Health. https:\/\/doi.org\/10.1186\/s12903-022-02329-5","journal-title":"BMC Oral Health"},{"issue":"4","key":"10649_CR33","doi-asserted-by":"publisher","first-page":"2092","DOI":"10.3390\/curroncol31040155","volume":"31","author":"T Kutuk","year":"2024","unstructured":"Kutuk T, Atak E, Villa A et al (2024) Interdisciplinary collaboration in head and neck cancer care: optimizing oral health management for patients undergoing radiation therapy. Curr Oncol 31(4):2092\u20132108. https:\/\/doi.org\/10.3390\/curroncol31040155","journal-title":"Curr Oncol"},{"key":"10649_CR34","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2021.09.107","volume":"46","author":"Y Wang","year":"2021","unstructured":"Wang Y, Zhang L, Zhuang B et al (2021) Predictive factors of crucial nutrition impact symptom clusters in patients with head and neck cancer with radiotherapy. Clin Nutr ESPEN 46:S578. https:\/\/doi.org\/10.1016\/j.clnesp.2021.09.107","journal-title":"Clin Nutr ESPEN"},{"issue":"3","key":"10649_CR35","doi-asserted-by":"publisher","first-page":"246","DOI":"10.4103\/jiaomr.jiaomr_3_22","volume":"34","author":"S Dharman","year":"2022","unstructured":"Dharman S, Keziah V, Maragathavalli G (2022) Assessment of onset and progression of chemoradiotherapy induced oral complications in head and neck cancer patients - a prospective study. J Indian Acad Oral Med Radiol 34(3):246\u2013252. https:\/\/doi.org\/10.4103\/jiaomr.jiaomr_3_22","journal-title":"J Indian Acad Oral Med Radiol"},{"issue":"2","key":"10649_CR36","doi-asserted-by":"publisher","first-page":"278","DOI":"10.18203\/2319-2003.ijbcp20180098","volume":"7","author":"M Srinivas","year":"2018","unstructured":"Srinivas M, Volabailu R, Shetty J, Sharma SN et al (2018) A study on management of oral cancer in a tertiary care hospital. Int J Basic Clin Pharmacol 7(2):278\u2013282. https:\/\/doi.org\/10.18203\/2319-2003.ijbcp20180098","journal-title":"Int J Basic Clin Pharmacol"},{"issue":"4","key":"10649_CR37","doi-asserted-by":"publisher","first-page":"193","DOI":"10.34175\/jno201804009","volume":"3","author":"XW Xin","year":"2018","unstructured":"Xin XW, Fang Y, Chen DS et al (2018) Nutritional support during chemotherapy in a patient with advanced gastric cancer: a case report. J Nutr Oncol 3(4):193\u2013197. https:\/\/doi.org\/10.34175\/jno201804009","journal-title":"J Nutr Oncol"},{"issue":"1","key":"10649_CR38","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1515\/fco-2015-0023","volume":"8","author":"E Galitis","year":"2017","unstructured":"Galitis E, Droukas V, Tzakis M et al (2017) Trismus and reduced quality of life in patients with oral squamous cell carcinoma, who received post-operative radiotherapy alone or combined with chemotherapy. Forum of Clinical Oncology 8(1):29\u201336. https:\/\/doi.org\/10.1515\/fco-2015-0023","journal-title":"Forum of Clinical Oncology"},{"issue":"5","key":"10649_CR39","doi-asserted-by":"publisher","first-page":"4537","DOI":"10.1007\/s00520-022-06871-4","volume":"30","author":"NH Kao","year":"2022","unstructured":"Kao NH, Iyer NG, Chua A et al (2022) Early quality of life outcomes after surgery in head and neck cancer survivors with EORTC QLQ-C30 and EORTC QLQ-HN35 in an Asian tertiary centre. Support Care Cancer 30(5):4537\u20134546. https:\/\/doi.org\/10.1007\/s00520-022-06871-4","journal-title":"Support Care Cancer"},{"issue":"18","key":"10649_CR40","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15184548","volume":"15","author":"V Sankar","year":"2023","unstructured":"Sankar V, Xu Y (2023) Oral complications from oropharyngeal cancer therapy. Cancers 15(18):4548. https:\/\/doi.org\/10.3390\/cancers15184548","journal-title":"Cancers"},{"key":"10649_CR41","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.neuroscience.2025.06.038","volume":"580","author":"G Buiret","year":"2025","unstructured":"Buiret G, Brignot H, Septier C et al (2025) Evaluating the etiology of metallic taste during head and neck cancer treatments: a study of facial and glossopharyngeal nerve interactions. Neuroscience 580:80\u201387. https:\/\/doi.org\/10.1016\/j.neuroscience.2025.06.038","journal-title":"Neuroscience"},{"issue":"10","key":"10649_CR42","doi-asserted-by":"publisher","DOI":"10.3390\/nu13103325","volume":"13","author":"L Togni","year":"2021","unstructured":"Togni L, Mascitti M, Vignini A et al (2021) Treatment-related dysgeusia in oral and oropharyngeal cancer: a comprehensive review. Nutrients 13(10):3325. https:\/\/doi.org\/10.3390\/nu13103325","journal-title":"Nutrients"},{"issue":"9","key":"10649_CR43","doi-asserted-by":"publisher","DOI":"10.3390\/nu13092921","volume":"13","author":"H Shono","year":"2021","unstructured":"Shono H, Tsutsumi R, Beppu K et al (2021) Dietary supplementation with monosodium glutamate suppresses chemotherapy-induced downregulation of the T1R3 taste receptor subunit in head and neck cancer patients. Nutrients 13(9):2921. https:\/\/doi.org\/10.3390\/nu13092921","journal-title":"Nutrients"},{"key":"10649_CR44","doi-asserted-by":"publisher","unstructured":"Ramalingam K, Krishnan M, Ramani P et al (2023) Quality of life assessment with European organisation for research and treatment of cancer questionnaire (Head and Neck Module 43) and Its clinicopathological correlation among patients treated for oral squamous cell carcinoma: an exploratory study. Cureus 15(7). https:\/\/doi.org\/10.7759\/cureus.34650.","DOI":"10.7759\/cureus.34650"},{"key":"10649_CR45","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-025-09204-3","author":"M Allner","year":"2025","unstructured":"Allner M, Rak A, Balk M et al (2025) Patient-reported outcomes in head and neck cancer: a cross-sectional analysis of quality of life domains across early and advanced UICC stages. Support Care Cancer. https:\/\/doi.org\/10.1007\/s00520-025-09204-3","journal-title":"Support Care Cancer"},{"issue":"12","key":"10649_CR46","doi-asserted-by":"publisher","DOI":"10.3390\/dj12120383","volume":"12","author":"AI D\u00edaz-Laclaustra","year":"2024","unstructured":"D\u00edaz-Laclaustra AI, \u00c1lvarez-Mart\u00ednez E, Ardila CM (2024) Influence of health system affiliation and pain manifestation on advanced oral cavity squamous cell carcinoma risk: a retrospective cohort study in a Latin American population. Dent J (Online) 12(12):383. https:\/\/doi.org\/10.3390\/dj12120383","journal-title":"Dent J (Online)"},{"issue":"1","key":"10649_CR47","doi-asserted-by":"publisher","DOI":"10.3390\/biology13010050","volume":"13","author":"DJ Aframian","year":"2024","unstructured":"Aframian DJ, Zedan A, Agbariah W et al (2024) Quantitive assessment of gustatory function and its association with demographics, and systemic morbidity. Biology 13(1):50. https:\/\/doi.org\/10.3390\/biology13010050","journal-title":"Biology"},{"key":"10649_CR48","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.26389","author":"P Silva","year":"2024","unstructured":"Silva P, Barreto G, Carlos A et al (2024) Dysgeusia increases the risk for death and other side effects during antineoplastic systemic treatment for solid tumors: a cross-sectional study. Med Oral Patol Oral Cir Bucal. https:\/\/doi.org\/10.4317\/medoral.26389","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"10649_CR49","doi-asserted-by":"publisher","DOI":"10.1093\/jncics\/pkae031","author":"P Jimenez-Labaig","year":"2024","unstructured":"Jimenez-Labaig P, Aymerich C, Bra\u00f1a I et al (2024) A comprehensive examination of mental health in patients with head and neck cancer: systematic review and meta-analysis. JNCI Cancer Spectr. https:\/\/doi.org\/10.1093\/jncics\/pkae031","journal-title":"JNCI Cancer Spectr"},{"issue":"3","key":"10649_CR50","doi-asserted-by":"publisher","first-page":"237","DOI":"10.4103\/2347-5625.311132","volume":"8","author":"Y Tsan","year":"2021","unstructured":"Tsan Y, Wung S, Lin M et al (2021) Predictors of quality of life change in head-and-neck cancer survivors during concurrent chemoradiotherapy: a prospective study. Asia Pac J Oncol Nurs 8(3):237\u2013245. https:\/\/doi.org\/10.4103\/2347-5625.311132","journal-title":"Asia Pac J Oncol Nurs"},{"issue":"11","key":"10649_CR51","doi-asserted-by":"publisher","first-page":"9527","DOI":"10.1007\/s00520-022-07322-w","volume":"30","author":"JA Vermaire","year":"2022","unstructured":"Vermaire JA, Raaijmakers CPJ, Monninkhof EM et al (2022) The course of swallowing problems in the first 2 years after diagnosis of head and neck cancer. Support Care Cancer 30(11):9527\u20139538. https:\/\/doi.org\/10.1007\/s00520-022-07322-w","journal-title":"Support Care Cancer"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-026-10649-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-026-10649-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-026-10649-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T14:48:43Z","timestamp":1778683723000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-026-10649-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,9]]},"references-count":51,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10649"],"URL":"https:\/\/doi.org\/10.1007\/s00520-026-10649-3","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,9]]},"assertion":[{"value":"23 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Ethics Committee of Fujian Medical University under the ethical number [2023] Fu Medical Ethics Review No. (126). All participants were de-identified, and written informed consent was obtained prior to the study. All procedures were conducted in accordance with the Declaration of Helsinki. Participant identities were strictly protected throughout the longitudinal follow-up.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial number"}}],"article-number":"417"}}