{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T15:18:01Z","timestamp":1778685481291,"version":"3.51.4"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Indolent non-Hodgkin lymphoma (iNHL) is a chronic, incurable lymphoid malignancy with a slow course. In absence of symptoms, a \u2018watchful waiting\u2019 approach is often chosen. The emotional burden of uncertainty and monitoring may affect patients\u2019 psychological well-being. This study investigates the extent of psychological distress in iNHL patients and its relationship with sociodemographics, clinical characteristics, and quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross-sectional study was conducted among adults with histologically confirmed indolent B-cell or T-cell NHL, recruited via a regional Dutch hospital and the online patient platform CMyLife. Data were collected through self-administered online questionnaires, including sociodemographics, clinical characteristics, psychological distress (HADS) and quality of life (EORTC QLQ-C30\/LG-NHL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 352 iNHL patients completed the questionnaires (response rate: 37.5%). The mean age was 69\u00a0years, 58.5% were male and psychological distress (HADS\u2009\u2265\u200913) was observed in 30.7% of participants. Distressed patients were more often female, less educated, more frequently in the period of watchful waiting, and had more medical comorbidities (p\u2009&lt;\u2009.01). They reported significantly lower health-related quality of life (HRQoL) (mean 51.2 vs. 77.6) and a higher symptom burden. Psychological distress was strongly correlated with lower HRQoL (r\u2009=\u2009\u2013.63). In hierarchical regression analysis, psychological distress was the strongest predictor of lower HRQoL (\u03b2\u2009=\u2009\u20130.605, p\u2009&lt;\u2009.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Approximately one-third of iNHL patients experience psychological distress, significantly associated with female gender, a lower education level, a watchful waiting approach, medical comorbidities, and a lower HRQoL. This underscores the importance of attention for these factors during consultations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00520-026-10737-4","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:36:14Z","timestamp":1777908974000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Psychological distress and quality of life in patients with indolent non-Hodgkin lymphoma"],"prefix":"10.1007","volume":"34","author":[{"given":"Jeanique W.","family":"Kuiper","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 A. E.","family":"Custers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ankie","family":"Kleinjan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilse P. G.","family":"Verpoorte-Botden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Floortje K. Ploos","family":"van Amstel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"issue":"5","key":"10737_CR1","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1093\/jnci\/85.5.365","volume":"85","author":"NK Aaronson","year":"1993","unstructured":"Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, Filiberti A, Flechtner H, Fleishman SB, De Haas JC (1993) The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 85(5):365\u2013376. https:\/\/doi.org\/10.1093\/jnci\/85.5.365","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"10737_CR2","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3389\/fpsyg.2022.872329","volume":"13","author":"G Agostinelli","year":"2022","unstructured":"Agostinelli G, Serpentini S, Annunziata MA, Muzzatti B, Spina M (2022) Cancer-related psychological distress in lymphoma survivor: an Italian cross-sectional study. Front Psychol 13(1):23\u201329. https:\/\/doi.org\/10.3389\/fpsyg.2022.872329","journal-title":"Front Psychol"},{"issue":"14","key":"10737_CR3","doi-asserted-by":"publisher","first-page":"3016","DOI":"10.1002\/cncr.31410","volume":"124","author":"LPJ Arts","year":"2018","unstructured":"Arts LPJ, Oerlemans S, Tick L, Koster A, Roerdink HTJ, Van De Poll-Franse LV (2018) More frequent use of health care services among distressed compared nondistressed survivors of lymphoma and chronic lymphocytic leukemia: results from the population-based PROFILES registry. Comparative Study 124(14):3016\u20133024. https:\/\/doi.org\/10.1002\/cncr.31410","journal-title":"Comparative Study"},{"issue":"1","key":"10737_CR4","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1097\/OR9.0000000000000041","volume":"3","author":"LPJ Arts","year":"2021","unstructured":"Arts LPJ, Oerlemans S, Schoormans D, Sanders ALTM, Stevens WBC, Posthuma EFM, Lidwine TW, Van De Poll-Franse LV (2021) Psychological distress among patients with lymphoma: the association with personality and coping strategy. Journal of Psychosocial Oncology Research and Practice 3(1):41. https:\/\/doi.org\/10.1097\/OR9.0000000000000041","journal-title":"Journal of Psychosocial Oncology Research and Practice"},{"issue":"20","key":"10737_CR5","doi-asserted-by":"publisher","first-page":"5226","DOI":"10.1158\/1078-0432.CCR-14-0437","volume":"20","author":"E Bachy","year":"2014","unstructured":"Bachy E, Salles G (2014) Are we nearing an era of chemotherapy-free management of indolent lymphoma? Clin Cancer Res 20(20):5226\u20135239. https:\/\/doi.org\/10.1158\/1078-0432.CCR-14-0437","journal-title":"Clin Cancer Res"},{"issue":"1","key":"10737_CR6","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1038\/s41598-025-93008-2","volume":"15","author":"CL Caldiroli","year":"2025","unstructured":"Caldiroli CL, Sarandacchi S, Tomasuolo M, Diso D, Castiglioni M, Procaccia R (2025) Resilience as a mediator of quality of life in cancer patients in healthcare services. Sci Rep 15(1):85\u201399. https:\/\/doi.org\/10.1038\/s41598-025-93008-2","journal-title":"Sci Rep"},{"issue":"1","key":"10737_CR7","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/s11845-024-03852-w","volume":"194","author":"E Carter","year":"2025","unstructured":"Carter E, Collier S, Plunkett R, Beirne E, Kelly BD (2025) Gender disparities in extreme psychological distress at cancer diagnosis and patients access to psycho-oncological care. Ir J Med Sci 194(1):45\u201353. https:\/\/doi.org\/10.1007\/s11845-024-03852-w","journal-title":"Ir J Med Sci"},{"key":"10737_CR8","unstructured":"Cohen J (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Lawrence Erlbaum Associates"},{"issue":"15","key":"10737_CR9","doi-asserted-by":"publisher","first-page":"9122","DOI":"10.3390\/ijerph19159122","volume":"19","author":"V Duarte","year":"2022","unstructured":"Duarte V, Ara\u00fajo N, Lopes C, Costa A, Ferreira A, Carneiro F, Oliveira J, Braga I, Morais S, Pacheco-Figueiredo L, Ruano L, Cruz VT, Pereira S, Lunet N (2022) Anxiety and depression in patients with prostate cancer, at cancer diagnosis and after a one-year follow-up. Internal Journal of Environmental Research and Public Health 19(15):9122. https:\/\/doi.org\/10.3390\/ijerph19159122","journal-title":"Internal Journal of Environmental Research and Public Health"},{"key":"10737_CR10","unstructured":"Dutch Federation of Cancer Patient Organizations (NFK) (2023) 97% of current and former cancer patients experience one or more complaints due to cancer or its treatment. Retrieved May 26, 2025, from https:\/\/nfk.nl\/actueel\/nieuws\/97-procent-van-de-ex-kankerpatienten-ervaart-door-kanker-of-de-behandeling-daarvan-een-of-meerdere-klachten"},{"issue":"5","key":"10737_CR11","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1111\/bjh.18139","volume":"197","author":"A Ekels","year":"2022","unstructured":"Ekels A, Van De Poll-Franse LV, Posthuma EFM, Kieffer J, Issa DE, Koster A, Nijziel MR, Pruijt JHFM, Stevens WBC, Tick LW, Oerlemans S (2022) Persistent symptoms of fatigue, neuropathy and role-functioning impairment among indolent non-Hodgkin lymphoma survivors: A longitudinal PROFILES registry study. British journal of hematology 197(5):590\u2013601. https:\/\/doi.org\/10.1111\/bjh.18139","journal-title":"British journal of hematology"},{"issue":"4","key":"10737_CR12","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1037\/0022-3514.46.4.839","volume":"46","author":"S Folkman","year":"1984","unstructured":"Folkman S (1984) Personal control and stress and coping processes: A theoretical analysis. J Pers Soc Psychol 46(4):839\u2013852. https:\/\/doi.org\/10.1037\/0022-3514.46.4.839","journal-title":"J Pers Soc Psychol"},{"issue":"1","key":"10737_CR13","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1007\/s00520-019-04805-1","volume":"28","author":"H G\u00f6tze","year":"2020","unstructured":"G\u00f6tze H, Friedrich M, Taubenheim S, Dietz A, Lordick F, Mehnert A (2020) Depression and anxiety in long-term survivors 5 and 10 years after cancer diagnosis. Support Care Cancer 28(1):211\u2013220. https:\/\/doi.org\/10.1007\/s00520-019-04805-1","journal-title":"Support Care Cancer"},{"issue":"12","key":"10737_CR14","doi-asserted-by":"publisher","first-page":"2895","DOI":"10.1007\/s11136-015-1039-y","volume":"24","author":"KM Holtzer-Goor","year":"2015","unstructured":"Holtzer-Goor KM, Schaafsma MR, Joosten P, Posthuma EFM, Wittebol S, Huijgens PC, Matthijssen EJM, Vreugdenhil G, Visser H, Peters WG, Erjavec Z, Wijermans PW, Daenen SMGJ, Van Der Hem KG, Van Oers MHJ, Uyl-De Groot CA (2015) Quality of life of patients with chronic lymphocytic leukaemia in the Netherlands: results of a longitudinal multicentre study. Qual Life Res 24(12):2895\u20132906. https:\/\/doi.org\/10.1007\/s11136-015-1039-y","journal-title":"Qual Life Res"},{"issue":"2","key":"10737_CR15","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1371\/journal.pone.0263672","volume":"17","author":"DA Howell","year":"2022","unstructured":"Howell DA, McCaughan D, Smith AG, Patmore R, Roman E (2022) Incurable but treatable: understanding and impact in chronic blood cancers \u2013 a qualitative study from the UK\u2019s haematological malignancy research network. PLoS ONE 17(2):26\u201336. https:\/\/doi.org\/10.1371\/journal.pone.0263672","journal-title":"PLoS ONE"},{"issue":"4","key":"10737_CR16","doi-asserted-by":"publisher","first-page":"e722","DOI":"10.1634\/theoncologist.2019-0348","volume":"25","author":"O Husson","year":"2020","unstructured":"Husson O, De Rooij BH, Kieffer J, Oerlemans S, Mols F, Aaronson NK, Van Der Graaf WTA, Van De Poll-Franse LV (2020) The EORTC QLQ-C30 summary score as prognostic factor for survival of patients with cancer in the real-world\u2019\u2019: results from the population-based PROFILES registry. Oncologist 25(4):e722\u2013e732. https:\/\/doi.org\/10.1634\/theoncologist.2019-0348","journal-title":"Oncologist"},{"key":"10737_CR17","unstructured":"IBM Corp. (2021). IBM SPSS Statistics for Windows (Version 28.0). [Computer software]. IBM Corp."},{"key":"10737_CR18","doi-asserted-by":"crossref","unstructured":"Kluin-Nelemans, J. C., & Tanasale-Huisman, E. A. (Reds.). (2013). Hematologie (2e druk). Bohn Stafleu van Loghum.","DOI":"10.1007\/978-90-313-9906-2"},{"issue":"3","key":"10737_CR19","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1037\/hea0000713","volume":"38","author":"K Kuba","year":"2019","unstructured":"Kuba K, Esser P, Mehnert A, Hinz A, Johansen C, Lordick F, G\u00f6tze H (2019) Risk for depression and anxiety in long-term survivors of hematologic cancer. Health Psychol 38(3):187\u2013195. https:\/\/doi.org\/10.1037\/hea0000713","journal-title":"Health Psychol"},{"key":"10737_CR20","unstructured":"Leukaemia Care. (2019). The emotional impact of watch and wait for Chronic Lymphatic Leukaemia [Poster presentation]. European Hematology Association 24 Digital Congress, Amsterdam, Netherlands.\u00a0https:\/\/media.leukaemiacare.org.uk\/wp\u2010content\/uploads\/The\u2010Emotional\u2010Impact\u2010of\u2010Watch\u2010and\u2010Wait\u2010for\u2010CLL\u2010EHA\u20102019\u2010Poster.pdf"},{"issue":"3","key":"10737_CR21","doi-asserted-by":"publisher","first-page":"2141","DOI":"10.3390\/curroncol29030173","volume":"29","author":"C Lopes","year":"2022","unstructured":"Lopes C, Lopes-Concei\u00e7\u00e3o L, Fontes F, Ferreira A, Pereira S, Lunet N, Ara\u00fajo N (2022) Prevalence and persistence of anxiety and depression over five years since breast cancer diagnosis \u2013 the NEON-BC prospective study. Curr Oncol 29(3):2141\u20132153. https:\/\/doi.org\/10.3390\/curroncol29030173","journal-title":"Curr Oncol"},{"issue":"2","key":"10737_CR22","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/S1470-2045(11)70002-X","volume":"12","author":"AJ Mitchell","year":"2011","unstructured":"Mitchell AJ, Chan M, Bhatti H, Halton M, Grassi L, Johansen C, Meader N (2011) Prevalence of depression, anxiety, and adjustment disorder in oncological, haematological, and palliative-care settings: a meta-analysis of 94 interview-based studies. Lancet Oncol 12(2):160\u2013174. https:\/\/doi.org\/10.1016\/S1470-2045(11)70002-X","journal-title":"Lancet Oncol"},{"key":"10737_CR23","unstructured":"Netherlands comprehensive cancer organization. (z.d.) Incidence of hematological cancer. Retrieved September 10, 2023, from https:\/\/iknl.nl\/kankersoorten\/hemato-oncologie\/registratie\/incidentie"},{"issue":"7","key":"10737_CR24","doi-asserted-by":"publisher","first-page":"1618","DOI":"10.1182\/bloodadvances.2024014821","volume":"9","author":"OO Odejide","year":"2025","unstructured":"Odejide OO, Cronin AM, Gray TF, Ablorh T, Ying A, Yang A, Ashley C, Tidswell A, Shi E, Yusufov M, Abel GA, Roemer L (2025) Anxiety and depression among patients newly diagnosed with lymphoma and myeloma. Blood Adv 9(7):1618\u20131629. https:\/\/doi.org\/10.1182\/bloodadvances.2024014821","journal-title":"Blood Adv"},{"issue":"1","key":"10737_CR25","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1007\/s11764-014-0367-1","volume":"8","author":"S Oerlemans","year":"2014","unstructured":"Oerlemans S, Mols F, Nijziel MR, Zijlstra WP, Coebergh JWW, Van De Poll-Fanse LV (2014) The course of anxiety and depression for patients with Hodgkin\u2019s lymphoma or diffuse large B cell lymphoma: a longitudinal study of the PROFILES registry. J Cancer Surviv 8(1):555\u2013564. https:\/\/doi.org\/10.1007\/s11764-014-0367-1","journal-title":"J Cancer Surviv"},{"key":"10737_CR26","doi-asserted-by":"publisher","unstructured":"Oerlemans, S., Efficace, F., Kyriakou, C., Freitas, A. C., Shamieh, O., Creutzberg, C. L., Lehmann, J., Petranovic, D., Nagele, E., Bredart, A., Dong, D., Scholz, C. W., Coacci, G., Molica, S., Griskevicius, L., Xochelli, A., Kieffer, J. M., Agelink-Van Rentergem, J. A., Alrjoub, W., . . . Van De Poll-Franse, L. V. (2023). International validation of two EORTC questionnaires for assessment of health-related quality of life for patients with high-grade non-Hodgkin lymphoma (QLQ-NHL-HG29) and low-grade non- Hodgkin lymphoma (QLQ-NHL-LG20). Cancer, 129(17):2727\u20132740. https:\/\/doi.org\/10.1002\/cncr.34822","DOI":"10.1002\/cncr.34822"},{"issue":"1","key":"10737_CR27","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1200\/JCO.1998.16.1.139","volume":"16","author":"D Osoba","year":"1998","unstructured":"Osoba D, Rodrigues G, Myles J, Zee B, Pater J (1998) Interpreting the significance of changes in health-related quality-of-life scores. J Clin Oncol 16(1):139\u2013144. https:\/\/doi.org\/10.1200\/JCO.1998.16.1.139","journal-title":"J Clin Oncol"},{"issue":"7","key":"10737_CR28","doi-asserted-by":"publisher","first-page":"1160","DOI":"10.1002\/pon.5632","volume":"30","author":"D Petrova","year":"2021","unstructured":"Petrova D, Redondo-S\u00e1nchez D, Rodr\u00edguez-Barranco M, Ruiz AR, Catena A, Garcia-Retamero R, S\u00e1nchez MJ (2021) Physical comorbidities as a marker for high risk of psychological distress in cancer patients. Psychooncology 30(7):1160\u20131166. https:\/\/doi.org\/10.1002\/pon.5632","journal-title":"Psychooncology"},{"key":"10737_CR29","doi-asserted-by":"publisher","unstructured":"Raphael D, Frey R, Gott M (2017) Psychosocial distress in haematological cancer survivors: an integrative review. Eur J Cancer Care 26(6):e12640. https:\/\/doi.org\/10.1111\/ecc.12640","DOI":"10.1111\/ecc.12640"},{"key":"10737_CR30","doi-asserted-by":"publisher","unstructured":"Sangha O, Stucki G, Liang MH, Fossel AH, Katz JN (2003) The Self-Administered Comorbidity Questionnaire: a new method to assess comorbidity for clinical and health services research. Arthritis & Rheumatology 49(2):156\u2013163. https:\/\/doi.org\/10.1002\/art.10993","DOI":"10.1002\/art.10993"},{"issue":"8","key":"10737_CR31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1136\/bmjopen-2022-070467","volume":"13","author":"R Sheridan","year":"2023","unstructured":"Sheridan R, McCaughan D, Hewison A, Roman E, Smith A, Patmore R, Howell D (2023) Experiences and preferences for psychosocial support: a qualitative study exploring the views of patients with chronic haematological cancers. BMJ journals 13(8):1\u201310. https:\/\/doi.org\/10.1136\/bmjopen-2022-070467","journal-title":"BMJ journals"},{"issue":"1","key":"10737_CR32","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3322\/caac.21442","volume":"68","author":"RL Siegel","year":"2018","unstructured":"Siegel RL, Miller KD, Jemal A (2018) Cancer statistics, 2018. A cancer journal for clinicians 68(1):7\u201330. https:\/\/doi.org\/10.3322\/caac.21442","journal-title":"A cancer journal for clinicians"},{"key":"10737_CR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2023.102510","volume":"113","author":"E Smyth","year":"2023","unstructured":"Smyth E, Cheah CY, Seymour JF (2023) Management of indolent B-cell lymphomas: a review of approved and emerging targeted therapies. Cancer Treat Rev 113:102510. https:\/\/doi.org\/10.1016\/j.ctrv.2023.102510","journal-title":"Cancer Treat Rev"},{"issue":"9","key":"10737_CR34","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2023-077067","volume":"14","author":"WZ Tang","year":"2024","unstructured":"Tang WZ, Mangantig E, Iskandar YHP, Cheng SL, Yusuf A, Jia K (2024) Prevalence and associated factors of psychological distress among patients with breast cancer: a systematic review and meta-analysis. BMJ Open 14(9):e077067. https:\/\/doi.org\/10.1136\/bmjopen-2023-077067","journal-title":"BMJ Open"},{"issue":"1","key":"10737_CR35","doi-asserted-by":"publisher","first-page":"2387","DOI":"10.1007\/s00520-021-06677-w","volume":"30","author":"MA Tilch","year":"2022","unstructured":"Tilch MA, Galle PR, Schattenberg JM, Kostev K, Labenz C (2022) Burden of depression and anxiety disorders per disease codes in patients with lymphoma in Germany. Support Care Cancer 30(1):2387\u20132395. https:\/\/doi.org\/10.1007\/s00520-021-06677-w","journal-title":"Support Care Cancer"},{"issue":"2","key":"10737_CR36","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.clml.2021.08.001","volume":"22","author":"KM Trevino","year":"2022","unstructured":"Trevino KM, Martin P, Chen Z, Leonard JP (2022) Worsening quality of life in indolent non-Hodgkin lymphoma and chronic lymphocytic leukemia patients in active surveillance: a 12-month longitudinal study. Clin Lymphoma Myeloma Leuk 22(2):82\u201388. https:\/\/doi.org\/10.1016\/j.clml.2021.08.001","journal-title":"Clin Lymphoma Myeloma Leuk"},{"key":"10737_CR37","doi-asserted-by":"publisher","first-page":"2453","DOI":"10.1007\/s00520-018-4523-4","volume":"27","author":"JD Troy","year":"2019","unstructured":"Troy JD, Locke SC, Samsa GP, Feliciano J, Richhariya A, LeBlanc TW (2019) Patient-reported distress in Hodgkin lymphoma across the survivorship continuum. Support Care Cancer 27:2453\u20132462. https:\/\/doi.org\/10.1007\/s00520-018-4523-4","journal-title":"Support Care Cancer"},{"issue":"3","key":"10737_CR38","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1136\/bmjopen-2013-003901","volume":"13","author":"S Watts","year":"2014","unstructured":"Watts S, Leydon G, Birch B, Prescott P, Lai L, Eardley S, Lewith G (2014) Depression and anxiety in prostate cancer: a systematic review and meta-analysis of prevalence rate. BMJ Open 13(3):39\u201345. https:\/\/doi.org\/10.1136\/bmjopen-2013-003901","journal-title":"BMJ Open"},{"issue":"15","key":"10737_CR39","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2024.1411647","volume":"21","author":"H Yao","year":"2024","unstructured":"Yao H, Xiong M, Cheng Y, Zhang Q, Luo Y, Ding X, Zhang C (2024) The relationship among body image, psychological distress, and quality of life in young breast cancer patients: a cross-sectional study. Front Psychol 21(15):1411647. https:\/\/doi.org\/10.3389\/fpsyg.2024.1411647","journal-title":"Front Psychol"},{"issue":"3","key":"10737_CR40","doi-asserted-by":"publisher","first-page":"308","DOI":"10.4103\/jcvjs.jcvjs_23_24","volume":"15","author":"C Yeung","year":"2024","unstructured":"Yeung C, Heard J, Lee Y, McCurdy M, Narayanan R, Kolowrat S, Gibbons L, Hagan T, Canseco JA, Hilibrand AS, Vaccaro AR, Schroeder GD, Kepler CK (2024) The prevalence of depression and anxiety in patients with metastatic disease to the spine. J Craniovertebr Junction Spine 15(3):308\u2013314. https:\/\/doi.org\/10.4103\/jcvjs.jcvjs_23_24","journal-title":"J Craniovertebr Junction Spine"},{"issue":"6","key":"10737_CR41","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1111\/ejh.13503","volume":"105","author":"P Youron","year":"2020","unstructured":"Youron P, Singh C, Jindal N, Malhotra P, Khadwal A, Jain A, Prakash G, Varma N, Varma S, Lad DP (2020) Quality of life in patients of chronic lymphocytic leukemia using the EORTC QLQ- C30 and QLQ-CLL17 questionnaire. Eur J Haematol 105(6):755\u2013762. https:\/\/doi.org\/10.1111\/ejh.13503","journal-title":"Eur J Haematol"},{"issue":"1","key":"10737_CR42","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1002\/1099-1611(200101\/02)10:1<19::aid-pon501>3.0.co;2-6","volume":"10","author":"J Zabora","year":"2001","unstructured":"Zabora J, BrintzenhofeSzoc K, Curbow B, Hooker C, Piantadosi S (2001) The prevalence of psychological distress by cancer site. Psychooncology 10(1):19\u201328. https:\/\/doi.org\/10.1002\/1099-1611(200101\/02)10:1%3c19::aid-pon501%3e3.0.co;2-6","journal-title":"Psychooncology"},{"key":"10737_CR43","doi-asserted-by":"crossref","unstructured":"Zigmond, A. S., & Snaith, R. P. (1983). The hospital anxiety and depression scale. Acta psychiatrica Scandinavica, 67(6):361\u2013370. j.1600\u20130447.1983.tb09716.x","DOI":"10.1111\/j.1600-0447.1983.tb09716.x"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-026-10737-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-026-10737-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-026-10737-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T14:49:27Z","timestamp":1778683767000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-026-10737-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":43,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10737"],"URL":"https:\/\/doi.org\/10.1007\/s00520-026-10737-4","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"21 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"497"}}