{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T02:58:55Z","timestamp":1781060335238,"version":"3.54.1"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T00:00:00Z","timestamp":1778889600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T00:00:00Z","timestamp":1778889600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100009934","name":"E\u00f6tv\u00f6s Lor\u00e1nd University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009934","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Although targeted therapies have prolonged survival in human epidermal growth factor receptor 2 (HER2)\u2013positive metastatic breast cancer, the resulting chronic disease trajectory is frequently accompanied by substantial psychological burden. This study aimed to conduct a preliminary investigation into the feasibility and psychological outcomes of a low-intensity, group-based cognitive-behavioral therapy intervention (CBT-OP-4) among women receiving palliative care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective feasibility study without a control group was undertaken involving 13 female participants (mean age\u2009=\u200963\u00a0years, SD\u2009=\u20098.05), all diagnosed with HER2-positive metastatic breast cancer. The four-session CBT-based group intervention targeted key psychological domains. Self-reported measures of distress, depression, anxiety, perceived stigma, self-compassion, and locus of control were administered pre- and post-intervention. Feasibility and acceptability were further examined via semi-structured qualitative interviews and standardized patient satisfaction instruments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Following the intervention, pre\u2013post improvements were observed in psychological distress, depressive symptoms, and perceived stigma. In parallel, participants demonstrated an increase in self-compassion. Overall, the program was rated as highly acceptable, with participants emphasizing the relevance and applicability of the intervention content within their illness context.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Findings from this preliminary study suggest that the CBT-OP-4 program is a feasible and acceptable psycho-oncological intervention for women with advanced-stage HER2-positive breast cancer receiving palliative care. The results offer initial empirical support for the incorporation of structured, evidence-based psychological interventions into the routine psychosocial management of this patient population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00520-026-10782-z","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T23:32:07Z","timestamp":1778887927000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility study of the Four-Session Cognitive-Behavioral Therapy\u2013based Psychological Intervention Program for women with HER2-positive metastatic breast cancer"],"prefix":"10.1007","volume":"34","author":[{"given":"Tam\u00e1s","family":"Szekeres","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1t\u00e9 \u00c1d\u00e1m","family":"Bal\u00e1zs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e1lint","family":"Madar\u00e1sz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsuzsa","family":"P\u00f3ti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00f3bert","family":"Urb\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdolna","family":"Dank","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriella","family":"Vizin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,16]]},"reference":[{"key":"10782_CR1","unstructured":"GLOBOCAN (2020) France: The International Agency for Research on Cancer. https:\/\/globocan.iarc.fr.\u00a0Accessed 13 Jan 2026"},{"key":"10782_CR2","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1038\/s41523-021-00345-2","volume":"7","author":"C Horr","year":"2021","unstructured":"Horr C, Buechler SA (2021) Breast cancer consensus subtypes: A system for subtyping breast cancer tumors based on gene expression. 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