{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T18:13:11Z","timestamp":1784052791282,"version":"3.55.0"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Blood Cancer United Scholar in Clinical Research Program"},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Acute lymphoblastic leukemia (ALL), the most common pediatric malignancy, involves multi-year treatment with substantial outpatient care, which contributes to high parent\/caregiver burden. Communication gaps and complex treatment regimens can leave families feeling unprepared for care of their children with ALL. To address this, we co-developed and pre-tested a digital health intervention supporting communication about what to expect during and after pediatric ALL treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Employing an iterative, stakeholder-driven process, we co-developed and pre-tested a family-centered interactive website, \u201cEXPECT,\u201d in two phases. Phase 1 included a secondary synthesis of stakeholder needed information and functionality (contextual inquiry), content creation, and website development, overseen by a multidisciplinary steering committee of clinical experts, patients, and families. In Phase 2 pre-testing, parents of patients with ALL rated the website\u2019s acceptability and provided feedback during semi-structured interviews.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Synthesis of previous patient, parent, and provider interviews revealed key priorities for intervention content and design which were addressed in content creation and web development. Pre-testing demonstrated high acceptability (4.7\/5). Participants highlighted EXPECT\u2019s user-friendliness and innovative features such as the interactive treatment roadmap. Participants preferred to receive early access to the website, within weeks of initiating treatment, and anticipated using EXPECT throughout therapy and the post-treatment period, primarily on mobile devices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>EXPECT co-development resulted in an acceptable digital health intervention to support families of children with ALL. EXPECT is being refined in response to feedback and will be tested in real-time treatment discussions in a multi-center pilot study to evaluate feasibility, use, and preliminary efficacy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00520-026-10835-3","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T07:38:25Z","timestamp":1781509105000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development and pre-testing of a family-centered digital intervention to help families know what to EXPECT from pediatric acute lymphoblastic leukemia therapy"],"prefix":"10.1007","volume":"34","author":[{"given":"Clara C.","family":"Hatch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydia Haupt","family":"Levy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kara M.","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Revette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marissa","family":"Krieger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Moynihan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha","family":"Carter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Selig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynda M.","family":"Vrooman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justine M.","family":"Kahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7591-2245","authenticated-orcid":false,"given":"Katie A.","family":"Greenzang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"10835_CR1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.30198","volume":"70","author":"KA Greenzang","year":"2023","unstructured":"Greenzang KA, Scavotto ML, Revette AC et al (2023) \u201cThere\u2019s no playbook for when your kid has cancer\u201d: desired elements of an electronic resource to support pediatric cancer communication. 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