{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T15:42:55Z","timestamp":1786203775514,"version":"build-2736575974"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T00:00:00Z","timestamp":1784332800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T00:00:00Z","timestamp":1784332800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100011758","name":"Ministrstvo za visoko \u0161olstvo, znanost in tehnologijo","doi-asserted-by":"publisher","award":["Grant numbers P3-0293 and J3-2519"],"award-info":[{"award-number":["Grant numbers P3-0293 and J3-2519"]}],"id":[{"id":"10.13039\/501100011758","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To test whether ultrasonic (US) scaling\u2013induced hard-tissue surface loss on irradiated teeth depends on irradiation dose,\u00a0type of scaler tip, angulation and orientation\u00a0and tooth region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In vitro study on 24 human molars irradiated with 0, 30, or 70\u00a0Gy. US scaling was robot-standardized (force 1 N, tips G6 and P20, angulation 15\u00b0 and 45\u00b0, orientation back and lateral) with medium power and water spray. Surface loss was graded on intraoral scans by three blinded observers on a six-band ordinal 0\u20135 scale (increasing with loss depth) and analyzed with cumulative-logit ordinal mixed models for median and maximum depth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      30\u00a0Gy significantly increased the odds of deeper surface loss with the back orientation (median:\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20092.43,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.039; max:\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20092.10,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.022); no 70\u00a0Gy contrast reached significance, indicating a dose-threshold effect. The G6 tip increased the odds of deeper damage substantially more than P20 across both depth outcomes (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and 45\u00b0 angulation together with the back orientation further amplified peak damage. The root was more susceptible than the crown (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2248 2.95,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>US instrumentation of irradiated teeth produced dose- and technique-dependent hard-tissue surface loss. Slim periodontal tips (P20) used at shallow angulation (15\u00b0) with a lateral orientation were associated with minimal surface loss across all doses and positions, whereas wider tip (G6) at 45\u00b0 with the back orientation produced consistent measurable wear, amplified on the root and by prior irradiation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00520-026-10992-5","type":"journal-article","created":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T12:58:08Z","timestamp":1784379488000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Damage of irradiated teeth by ultrasonic scaling: an in vitro study"],"prefix":"10.1007","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3866-6572","authenticated-orcid":false,"given":"Jana","family":"Krape\u017e","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marko","family":"Polajnar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klemen","family":"Leopold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob","family":"Peterlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Attila","family":"\u0160arvari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitjan","family":"Kalin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ale\u0161","family":"Fidler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,18]]},"reference":[{"issue":"6","key":"10992_CR1","doi-asserted-by":"publisher","first-page":"2977","DOI":"10.1007\/s00520-019-05171-8","volume":"28","author":"M De Pauli Paglioni","year":"2020","unstructured":"De Pauli Paglioni M, Palmier NR, Prado-Ribeiro AC, Fregnani ER, Gavi\u00e3o MBD, Brand\u00e3o TB et al (2020) The impact of radiation caries in the quality of life of head and neck cancer patients. Support Care Cancer 28(6):2977\u20132984. https:\/\/doi.org\/10.1007\/s00520-019-05171-8","journal-title":"Support Care Cancer"},{"key":"10992_CR2","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/j.oraloncology.2019.104484","volume":"1","author":"C Moore","year":"2020","unstructured":"Moore C, McLister C, Cardwell C, O\u2019Neill C, Donnelly M, McKenna G (2020) Dental caries following radiotherapy for head and neck cancer: a systematic review. Oral Oncol 1:100. https:\/\/doi.org\/10.1016\/j.oraloncology.2019.104484","journal-title":"Oral Oncol"},{"issue":"5","key":"10992_CR3","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-024-08522-2","volume":"32","author":"RV Monteiro","year":"2024","unstructured":"Monteiro RV, Lins RBE, Lima RBW, Fischer K, De Souza GM (2024) Preventive and restorative alternatives to caries by irradiation: a scoping review. Support Care Cancer 32(5):327. https:\/\/doi.org\/10.1007\/s00520-024-08522-2","journal-title":"Support Care Cancer"},{"issue":"7","key":"10992_CR4","doi-asserted-by":"publisher","first-page":"e181","DOI":"10.1016\/j.dental.2022.04.014","volume":"38","author":"L Douchy","year":"2022","unstructured":"Douchy L, Gauthier R, Abouelleil-Sayed H, Colon P, Grosgogeat B, Bosco J (2022) The effect of therapeutic radiation on dental enamel and dentin: a systematic review. Dent Mater 38(7):e181-201. https:\/\/doi.org\/10.1016\/j.dental.2022.04.014","journal-title":"Dent Mater"},{"issue":"1","key":"10992_CR5","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/s00784-013-1034-z","volume":"18","author":"HFJ Lieshout","year":"2014","unstructured":"Lieshout HFJ, Bots CP (2014) The effect of radiotherapy on dental hard tissue\u2014a systematic review. Clin Oral Investig 18(1):17\u201324. https:\/\/doi.org\/10.1007\/s00784-013-1034-z","journal-title":"Clin Oral Investig"},{"key":"10992_CR6","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.23212","author":"J Fonseca","year":"2020","unstructured":"Fonseca J, Troconis C, Palmier N, Gomes-Silva W, Paglioni M, Ara\u00fajo A et al (2020) The impact of head and neck radiotherapy on the dentine-enamel junction: a systematic review. Med Oral Patol Oral Cir Bucal. https:\/\/doi.org\/10.4317\/medoral.23212","journal-title":"Med Oral Patol Oral Cir Bucal"},{"issue":"5","key":"10992_CR7","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1016\/j.archoralbio.2015.02.020","volume":"60","author":"R Reed","year":"2015","unstructured":"Reed R, Xu C, Liu Y, Gorski JP, Wang Y, Walker MP (2015) Radiotherapy effect on nano-mechanical properties and chemical composition of enamel and dentine. Arch Oral Biol 60(5):690\u2013697. https:\/\/doi.org\/10.1016\/j.archoralbio.2015.02.020","journal-title":"Arch Oral Biol"},{"issue":"19","key":"10992_CR8","doi-asserted-by":"publisher","first-page":"4423","DOI":"10.1002\/cncr.33100","volume":"126","author":"S Elad","year":"2020","unstructured":"Elad S, Cheng KKF, Lalla RV, Yarom N, Hong C, Logan RM et al (2020) MASCC\/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer 126(19):4423\u20134431. https:\/\/doi.org\/10.1002\/cncr.33100","journal-title":"Cancer"},{"issue":"16","key":"10992_CR9","doi-asserted-by":"publisher","first-page":"1975","DOI":"10.1200\/JCO.23.02750","volume":"42","author":"DE Peterson","year":"2024","unstructured":"Peterson DE, Koyfman SA, Yarom N, Lynggaard CD, Ismaila N, Forner LE et al (2024Jun 1) Prevention and management of osteoradionecrosis in patients with head and neck cancer treated with radiation therapy: ISOO-MASCC-ASCO guideline. J Clin Oncol 42(16):1975\u20131996. https:\/\/doi.org\/10.1200\/JCO.23.02750","journal-title":"J Clin Oncol"},{"issue":"10","key":"10992_CR10","doi-asserted-by":"publisher","first-page":"3949","DOI":"10.1007\/s00520-019-04848-4","volume":"27","author":"CHL Hong","year":"2019","unstructured":"Hong CHL, Gueiros LA, Fulton JS, Cheng KKF, Kandwal A, Galiti D et al (2019) Systematic review of basic oral care for the management of oral mucositis in cancer patients and clinical practice guidelines. Support Care Cancer 27(10):3949\u20133967. https:\/\/doi.org\/10.1007\/s00520-019-04848-4","journal-title":"Support Care Cancer"},{"issue":"8","key":"10992_CR11","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1007\/s00520-024-08688-9","volume":"32","author":"C Hong","year":"2024","unstructured":"Hong C, Jensen SB, Vissink A, Bonomo P, Santos-Silva AR, Gueiros LA et al (2024Aug) MASCC\/ISOO clinical practice statement: management of salivary gland hypofunction and xerostomia in cancer patients. Support Care Cancer 32(8):548. https:\/\/doi.org\/10.1007\/s00520-024-08688-9","journal-title":"Support Care Cancer"},{"key":"10992_CR12","doi-asserted-by":"publisher","DOI":"10.4317\/jced.52557","author":"I Lanzos","year":"2015","unstructured":"Lanzos I, Herrera D, Lanzos E, Sanz M (2015) A critical assessment of oral care protocols for patients under radiation therapy in the regional University Hospital Network of Madrid (Spain). J Clin Exp Dent. https:\/\/doi.org\/10.4317\/jced.52557","journal-title":"J Clin Exp Dent"},{"issue":"1","key":"10992_CR13","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1002\/cre2.242","volume":"6","author":"N Bohm","year":"2020","unstructured":"Bohm N, Karlsson C, Skoogh Andersson J, Almst\u00e5hl A (2020) Variations in odontological care routines for patients undergoing treatment for head and neck cancer in county councils\/regions of Sweden. Clin Exp Dent Res 6(1):3\u201315. https:\/\/doi.org\/10.1002\/cre2.242","journal-title":"Clin Exp Dent Res"},{"key":"10992_CR14","doi-asserted-by":"publisher","unstructured":"Fidler A, Ani\u010din A, Didanovi\u0107 V, Dov\u0161ak T, Ga\u0161pirc B, Gro\u0161elj A et al (2022) Recommendations for the dental management of adult patients with head and neck cancer in Slovenia treated with radiation therapy. Onkol Med-Sci J 28\u201332. https:\/\/doi.org\/10.25670\/OI2022-004ON","DOI":"10.25670\/OI2022-004ON"},{"issue":"s8","key":"10992_CR15","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1111\/j.1600-051X.2008.01258.x","volume":"35","author":"AD Walmsley","year":"2008","unstructured":"Walmsley AD, Lea SC, Landini G, Moses AJ (2008Sep) Advances in power driven pocket\/root instrumentation. J Clin Periodontol 35(s8):22\u201328. https:\/\/doi.org\/10.1111\/j.1600-051X.2008.01258.x","journal-title":"J Clin Periodontol"},{"key":"10992_CR16","volume-title":"Ultrasonic periodontal debridement: theory and technique","author":"MD George","year":"2023","unstructured":"George MD, Botbyl D, Donley TG, Preshaw PM (2023) Ultrasonic periodontal debridement: theory and technique, 2. Edition. Wiley-Blackwell, Hoboken","edition":"2. Edition"},{"issue":"3","key":"10992_CR17","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1177\/0022034508330267","volume":"88","author":"SC Lea","year":"2009","unstructured":"Lea SC, Felver B, Landini G, Walmsley AD (2009) Ultrasonic scaler oscillations and tooth-surface defects. J Dent Res 88(3):229\u2013234. https:\/\/doi.org\/10.1177\/0022034508330267","journal-title":"J Dent Res"},{"issue":"5","key":"10992_CR18","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-024-05671-w","volume":"28","author":"LA Berto","year":"2024","unstructured":"Berto LA, Ettmayer JB, Stutzer D, Nietzsche S, Niederhauser T, Burger J et al (2024) In-vitro effects of novel periodontal scalers with a planar ultrasonic piezoelectric transducer on periodontal biofilm removal, dentine surface roughness, and periodontal ligament fibroblasts adhesion. Clin Oral Investig 28(5):294. https:\/\/doi.org\/10.1007\/s00784-024-05671-w","journal-title":"Clin Oral Investig"},{"issue":"1","key":"10992_CR19","doi-asserted-by":"publisher","DOI":"10.1038\/srep11568","volume":"5","author":"P Qing","year":"2015","unstructured":"Qing P, Huang S, Gao S, Qian L, Yu H (2015) Effect of gamma irradiation on the wear behaviour of human tooth enamel. Sci Rep 5(1):11568. https:\/\/doi.org\/10.1038\/srep11568","journal-title":"Sci Rep"},{"issue":"9","key":"10992_CR20","doi-asserted-by":"publisher","first-page":"2379","DOI":"10.1007\/s00784-016-1731-5","volume":"20","author":"P Qing","year":"2016","unstructured":"Qing P, Huang S, Gao S, Qian L, Yu H (2016) Effect of gamma irradiation on the wear behavior of human tooth dentin. Clin Oral Investig 20(9):2379\u20132386. https:\/\/doi.org\/10.1007\/s00784-016-1731-5","journal-title":"Clin Oral Investig"},{"issue":"2","key":"10992_CR21","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1159\/000452866","volume":"51","author":"CC Madrid","year":"2017","unstructured":"Madrid CC, De Pauli Paglioni M, Line SR, Vasconcelos KG, Brand\u00e3o TB, Lopes MA et al (2017) Structural analysis of enamel in teeth from head-and-neck cancer patients who underwent radiotherapy. Caries Res 51(2):119\u2013128. https:\/\/doi.org\/10.1159\/000452866","journal-title":"Caries Res"},{"issue":"6","key":"10992_CR22","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1016\/j.joen.2024.02.018","volume":"50","author":"G Pauletto","year":"2024","unstructured":"Pauletto G, Soares PM, Baumhardt T, Rocha Pereira GK, Souza Bier CA (2024) Effect of radiotherapy and taper of root canal preparation on the biomechanical behavior of mesial roots of mandibular molars. J Endod 50(6):827\u2013834. https:\/\/doi.org\/10.1016\/j.joen.2024.02.018","journal-title":"J Endod"},{"issue":"2","key":"10992_CR23","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1007\/s10266-025-01140-2","volume":"114","author":"GR Bertolini","year":"2026","unstructured":"Bertolini GR, Cronenbold TJ, Prado HS, de-Assis HC, Mazzi-Chaves JF, De Queiroz AM et al (2026) Effect of radiotherapy on the biomechanical preparation of different instrumentation kinematics. Odontology 114(2):642\u2013651. https:\/\/doi.org\/10.1007\/s10266-025-01140-2","journal-title":"Odontology"},{"key":"10992_CR24","doi-asserted-by":"crossref","unstructured":"Flemming TF, Petersilka GJ, Mehl A, Hickel R, Klaiber B (1998) Working parameters of magnetostristive ultrasonic scalerinfl uencing root substance removal in-vitro. J Periodotol 69(5):547-553. https:\/\/doi.org\/10.1902-jop.1998.69.5.547","DOI":"10.1902\/jop.1998.69.5.547"},{"issue":"6","key":"10992_CR25","doi-asserted-by":"publisher","first-page":"579","DOI":"10.4103\/JIOH.JIOH_121_20","volume":"12","author":"M Al Ankily","year":"2020","unstructured":"Al Ankily M, Makkeyah F, Bakr M, Shamel M (2020Nov 1) Effect of different scaling methods and materials on the enamel surface topography: an in vitro SEM study. J Int Oral Health 12(6):579\u2013585. https:\/\/doi.org\/10.4103\/JIOH.JIOH_121_20","journal-title":"J Int Oral Health"},{"key":"10992_CR26","doi-asserted-by":"publisher","unstructured":"Christensen RHB (2010) ordinal: regression models for ordinal data [Internet]. [cited 2026 Apr 23]. p 2025.12\u201329. Available from: https:\/\/CRAN.R-project.org\/package=ordinalhttps:\/\/doi.org\/10.32614\/CRAN.package.ordinal","DOI":"10.32614\/CRAN.package.ordinal"},{"issue":"3","key":"10992_CR27","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1002\/bimj.200810425","volume":"50","author":"T Hothorn","year":"2008","unstructured":"Hothorn T, Bretz F, Westfall P (2008) Simultaneous inference in general parametric models. Biom J 50(3):346\u2013363. https:\/\/doi.org\/10.1002\/bimj.200810425","journal-title":"Biom J"},{"issue":"5","key":"10992_CR28","doi-asserted-by":"publisher","DOI":"10.3390\/biology11050784","volume":"11","author":"E Gualdi-Russo","year":"2022","unstructured":"Gualdi-Russo E, Saguto I, Frisoni P, Neri M, Rinaldo N (2022) Tooth cementum thickness as a method of age estimation in the forensic context. Biology (Basel) 11(5):784. https:\/\/doi.org\/10.3390\/biology11050784","journal-title":"Biology (Basel)"},{"issue":"3","key":"10992_CR29","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1152\/physrev.00030.2016","volume":"97","author":"RS Lacruz","year":"2017","unstructured":"Lacruz RS, Habelitz S, Wright JT, Paine ML (2017) Dental enamel formation and implications for oral health and disease. Physiol Rev 97(3):939\u2013993. https:\/\/doi.org\/10.1152\/physrev.00030.2016","journal-title":"Physiol Rev"},{"issue":"4","key":"10992_CR30","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1007\/s00784-016-1861-9","volume":"21","author":"C Graetz","year":"2017","unstructured":"Graetz C, Plaumann A, Wittich R, Springer C, Kahl M, D\u00f6rfer CE et al (2017) Removal of simulated biofilm: an evaluation of the effect on root surfaces roughness after scaling. Clin Oral Investig 21(4):1021\u20131028. https:\/\/doi.org\/10.1007\/s00784-016-1861-9","journal-title":"Clin Oral Investig"},{"issue":"5","key":"10992_CR31","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1902\/jop.1998.69.5.547","volume":"69","author":"TF Flemmig","year":"1998","unstructured":"Flemmig TF, Petersilka GJ, Mehl A, Hickel R, Klaiber B (1998) Working parameters of a magnetostrictive ultrasonic sealer influencing root substance removal in vitro. J Periodontol 69(5):547\u2013553. https:\/\/doi.org\/10.1902\/jop.1998.69.5.547","journal-title":"J Periodontol"},{"issue":"11","key":"10992_CR32","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1111\/j.1600-051X.2004.00601.x","volume":"31","author":"S Jepsen","year":"2004","unstructured":"Jepsen S, Ayna M, Hedderich J, Eberhard J (2004) Significant influence of scaler tip design on root substance loss resulting from ultrasonic scaling: a laserprofilometric in vitro study. J Clin Periodontol 31(11):1003\u20131006. https:\/\/doi.org\/10.1111\/j.1600-051X.2004.00601.x","journal-title":"J Clin Periodontol"},{"issue":"11","key":"10992_CR33","doi-asserted-by":"publisher","first-page":"8667","DOI":"10.1007\/s00520-022-07168-2","volume":"30","author":"JMP Dezanetti","year":"2022","unstructured":"Dezanetti JMP, Nascimento BL, Orsi JSR, Souza EM (2022) Effectiveness of glass ionomer cements in the restorative treatment of radiation-related caries \u2014 a systematic review. Support Care Cancer 30(11):8667\u20138678. https:\/\/doi.org\/10.1007\/s00520-022-07168-2","journal-title":"Support Care Cancer"},{"issue":"5","key":"10992_CR34","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-024-08476-5","volume":"32","author":"C Atalay","year":"2024","unstructured":"Atalay C, Yazici AR (2024) Effect of radiotherapy on the surface roughness and microhardness of contemporary bioactive restorative materials. Support Care Cancer 32(5):295. https:\/\/doi.org\/10.1007\/s00520-024-08476-5","journal-title":"Support Care Cancer"},{"issue":"8","key":"10992_CR35","doi-asserted-by":"publisher","first-page":"1354","DOI":"10.1016\/j.dental.2022.06.022","volume":"38","author":"P Charalambous","year":"2022","unstructured":"Charalambous P, O\u2019Toole S, Austin R, Bartlett D (2022) The threshold of an intra oral scanner to measure lesion depth on natural unpolished teeth. Dent Mater 38(8):1354\u20131361. https:\/\/doi.org\/10.1016\/j.dental.2022.06.022","journal-title":"Dent Mater"},{"key":"10992_CR36","doi-asserted-by":"publisher","DOI":"10.3390\/jimaging9070134","author":"F Angelone","year":"2023","unstructured":"Angelone F, Ponsiglione AM, Ricciardi C, Cesarelli G, Sansone M, Amato F (2023) Diagnostic applications of intraoral scanners: a systematic review. J Imaging. https:\/\/doi.org\/10.3390\/jimaging9070134","journal-title":"J Imaging"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-026-10992-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-026-10992-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-026-10992-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T14:55:27Z","timestamp":1786200927000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-026-10992-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,18]]},"references-count":36,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10992"],"URL":"https:\/\/doi.org\/10.1007\/s00520-026-10992-5","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-9515791\/v1","asserted-by":"object"}]},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,18]]},"assertion":[{"value":"24 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 May 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 July 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 July 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Commission of the Republic of Slovenia for Medical Ethics (No. N0120-351\/2021\/6).","order":1,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent was obtained from all patients before tooth extraction.","order":2,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable\u2014the manuscript contains no individually identifiable participant data.","order":3,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"777"}}