{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T03:42:44Z","timestamp":1786246964494,"version":"build-2736575974"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:00:00Z","timestamp":1785024000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:00:00Z","timestamp":1785024000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1007\/s00520-026-11043-9","type":"journal-article","created":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T20:36:12Z","timestamp":1785098172000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predicting taxane-induced peripheral neuropathy by nailfold capillaroscopy: The CAPNEU pilot study"],"prefix":"10.1007","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8253-5046","authenticated-orcid":false,"given":"Ali","family":"Alkan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melike","family":"Ersoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Utku","family":"Cenikli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emine Figen","family":"Tarhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zg\u00fcr","family":"Tanr\u0131verdi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,26]]},"reference":[{"issue":"1","key":"11043_CR1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-024-02108-4","volume":"10","author":"X Xiong","year":"2025","unstructured":"Xiong X, Zheng LW, Ding Y et al (2025) Breast cancer: pathogenesis and treatments. Signal Transduct Target Ther 10(1):49. https:\/\/doi.org\/10.1038\/s41392-024-02108-4","journal-title":"Signal Transduct Target Ther"},{"issue":"4","key":"11043_CR2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.59266","volume":"16","author":"A Jivani","year":"2024","unstructured":"Jivani A, Shinde RK (2024) A comprehensive review of taxane treatment in breast cancer: clinical perspectives and toxicity profiles. Cureus 16(4):e59266. https:\/\/doi.org\/10.7759\/cureus.59266","journal-title":"Cureus"},{"key":"11043_CR3","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.ctrv.2015.11.009","volume":"43","author":"L Biganzoli","year":"2016","unstructured":"Biganzoli L, Aapro M, Loibl S et al (2016) Taxanes in the treatment of breast cancer: have we better defined their role in older patients? A position paper from a SIOG Task Force. Cancer Treat Rev 43:19\u201326. https:\/\/doi.org\/10.1016\/j.ctrv.2015.11.009","journal-title":"Cancer Treat Rev"},{"issue":"6","key":"11043_CR4","doi-asserted-by":"publisher","first-page":"CD003366","DOI":"10.1002\/14651858.CD003366.pub3","volume":"2015","author":"D Ghersi","year":"2015","unstructured":"Ghersi D, Willson ML, Chan MM et al (2015) Taxane-containing regimens for metastatic breast cancer. Cochrane Database Syst Rev 2015(6):CD003366. https:\/\/doi.org\/10.1002\/14651858.CD003366.pub3","journal-title":"Cochrane Database Syst Rev"},{"key":"11043_CR5","doi-asserted-by":"publisher","unstructured":"Rivera DR, Ganz PA, Weyrich MS, et al. (2018) Chemotherapy-Associated Peripheral Neuropathy in Patients With Early-Stage Breast Cancer: A Systematic Review. J Natl Cancer Inst. 110(2). https:\/\/doi.org\/10.1093\/jnci\/djx140","DOI":"10.1093\/jnci\/djx140"},{"key":"11043_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2024.116070","volume":"222","author":"J Ollodart","year":"2024","unstructured":"Ollodart J, Steele LR, Romero-Sandoval EA et al (2024) Contributions of neuroimmune interactions to chemotherapy-induced peripheral neuropathy development and its prevention\/therapy. Biochem Pharmacol 222:116070. https:\/\/doi.org\/10.1016\/j.bcp.2024.116070","journal-title":"Biochem Pharmacol"},{"issue":"1","key":"11043_CR7","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-14870-y","volume":"12","author":"N Rattanakrong","year":"2022","unstructured":"Rattanakrong N, Siriphorn A, Boonyong S (2022) Incidence density and factors associated with peripheral neuropathy among women with breast cancer during taxane-based chemotherapy. Sci Rep 12(1):10632. https:\/\/doi.org\/10.1038\/s41598-022-14870-y","journal-title":"Sci Rep"},{"issue":"2","key":"11043_CR8","doi-asserted-by":"publisher","first-page":"152","DOI":"10.3390\/toxics3020152","volume":"3","author":"R Velasco","year":"2015","unstructured":"Velasco R, Bruna J (2015) Taxane-induced peripheral neurotoxicity. Toxics 3(2):152\u2013169. https:\/\/doi.org\/10.3390\/toxics3020152","journal-title":"Toxics"},{"issue":"4","key":"11043_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.soncn.2024.151687","volume":"40","author":"C Visovsky","year":"2024","unstructured":"Visovsky C, Wodzinski PT, Haladay D et al (2024) Fall risk associated with taxanes: focus on chemotherapy-induced peripheral neuropathy. Semin Oncol Nurs 40(4):151687. https:\/\/doi.org\/10.1016\/j.soncn.2024.151687","journal-title":"Semin Oncol Nurs"},{"key":"11043_CR10","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2025.15254","author":"M Godiveau","year":"2025","unstructured":"Godiveau M, Jahanmohan JP, Abrial C et al (2025) Chemotherapy-induced peripheral neuropathy in patients with breast cancer treated with taxanes (review). Oncol Lett. https:\/\/doi.org\/10.3892\/ol.2025.15254","journal-title":"Oncol Lett"},{"issue":"2","key":"11043_CR11","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1111\/ajco.13923","volume":"20","author":"C Liang","year":"2024","unstructured":"Liang C, Zhang Y, Chen QY et al (2024) Risk factors for taxane-induced peripheral neuropathy in patients with breast cancer. Asia Pac J Clin Oncol 20(2):220\u2013227. https:\/\/doi.org\/10.1111\/ajco.13923","journal-title":"Asia Pac J Clin Oncol"},{"issue":"1","key":"11043_CR12","doi-asserted-by":"publisher","DOI":"10.1038\/s41698-024-00594-x","volume":"8","author":"K Engvall","year":"2024","unstructured":"Engvall K, Uvdal H, Bjorn N et al (2024) Prediction models of persistent taxane-induced peripheral neuropathy among breast cancer survivors using whole-exome sequencing. npj Precis Oncol 8(1):102. https:\/\/doi.org\/10.1038\/s41698-024-00594-x","journal-title":"npj Precis Oncol"},{"key":"11043_CR13","doi-asserted-by":"publisher","DOI":"10.26508\/lsa.202402791","author":"S Taib","year":"2025","unstructured":"Taib S, Durand J, Dehais V et al (2025) Vascular dysfunction is at the onset of oxaliplatin-induced peripheral neuropathy symptoms in mice. Life Sci Alliance. https:\/\/doi.org\/10.26508\/lsa.202402791","journal-title":"Life Sci Alliance"},{"issue":"7","key":"11043_CR14","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1055\/a-2499-9856","volume":"85","author":"S Reuter","year":"2025","unstructured":"Reuter S, Bajorat R, Muller-Graf F et al (2025) The role of microcirculatory dysfunction during paclitaxel treatment as a critical co-factor for the development of chemotherapy-induced peripheral neuropathy. Geburtshilfe Frauenheilkd 85(7):710\u2013723. https:\/\/doi.org\/10.1055\/a-2499-9856","journal-title":"Geburtshilfe Frauenheilkd"},{"issue":"14","key":"11043_CR15","doi-asserted-by":"publisher","first-page":"5731","DOI":"10.1523\/JNEUROSCI.19-14-05731.1999","volume":"19","author":"M Sondell","year":"1999","unstructured":"Sondell M, Lundborg G, Kanje M (1999) Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system. J Neurosci 19(14):5731\u20135740. https:\/\/doi.org\/10.1523\/JNEUROSCI.19-14-05731.1999","journal-title":"J Neurosci"},{"key":"11043_CR16","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.neuroscience.2013.03.050","volume":"244","author":"A Verheyen","year":"2013","unstructured":"Verheyen A, Peeraer E, Lambrechts D et al (2013) Therapeutic potential of VEGF and VEGF-derived peptide in peripheral neuropathies. Neuroscience 244:77\u201389. https:\/\/doi.org\/10.1016\/j.neuroscience.2013.03.050","journal-title":"Neuroscience"},{"issue":"12","key":"11043_CR17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0168707","volume":"11","author":"A Matsuoka","year":"2016","unstructured":"Matsuoka A, Maeda O, Mizutani T et al (2016) Bevacizumab Exacerbates Paclitaxel-Induced Neuropathy: A Retrospective Cohort Study. PLoS ONE 11(12):e0168707. https:\/\/doi.org\/10.1371\/journal.pone.0168707","journal-title":"PLoS ONE"},{"issue":"8","key":"11043_CR18","first-page":"4213","volume":"34","author":"T Ohno","year":"2014","unstructured":"Ohno T, Mine T, Yoshioka H et al (2014) Management of peripheral neuropathy induced by nab-paclitaxel treatment for breast cancer. Anticancer Res 34(8):4213\u20134216","journal-title":"Anticancer Res"},{"issue":"1","key":"11043_CR19","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-023-11079-8","volume":"23","author":"YJ Kang","year":"2023","unstructured":"Kang YJ, Yoon CI, Yang YJ et al (2023) A randomized controlled trial using surgical gloves to prevent chemotherapy-induced peripheral neuropathy by paclitaxel in breast cancer patients (AIUR trial). BMC Cancer 23(1):570. https:\/\/doi.org\/10.1186\/s12885-023-11079-8","journal-title":"BMC Cancer"},{"key":"11043_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2025.115791","volume":"229","author":"B Hanvic","year":"2025","unstructured":"Hanvic B, Joureau-Chabert A, Ouldbey Y et al (2025) Compression therapy with surgical gloves compared to cold therapy with frozen gloves in preventing paclitaxel-induced peripheral neuropathy: results from the prospective ELEGANT trial in patients with breast cancer. Eur J Cancer 229:115791. https:\/\/doi.org\/10.1016\/j.ejca.2025.115791","journal-title":"Eur J Cancer"},{"issue":"1.2","key":"11043_CR21","doi-asserted-by":"publisher","first-page":"6","DOI":"10.2152\/jmi.68.6","volume":"68","author":"N Mansueto","year":"2021","unstructured":"Mansueto N, Rotondo C, Corrado A et al (2021) Nailfold capillaroscopy: a comprehensive review on common findings and clinical usefulness in non-rheumatic disease. J Med Invest 68(1.2):6\u201314. https:\/\/doi.org\/10.2152\/jmi.68.6","journal-title":"J Med Invest"},{"key":"11043_CR22","doi-asserted-by":"publisher","DOI":"10.3390\/nu16121914","author":"M Komai","year":"2024","unstructured":"Komai M, Takeno D, Fujii C et al (2024) Nailfold capillaroscopy: a comprehensive review on its usefulness in both clinical diagnosis and improving unhealthy dietary lifestyles. Nutrients. https:\/\/doi.org\/10.3390\/nu16121914","journal-title":"Nutrients"},{"issue":"3","key":"11043_CR23","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/S1053-4296(03)00031-6","volume":"13","author":"A Trotti","year":"2003","unstructured":"Trotti A, Colevas AD, Setser A et al (2003) CTCAE v3.0: development of a comprehensive grading system for the adverse effects of cancer treatment. Semin Radiat Oncol 13(3):176\u2013181. https:\/\/doi.org\/10.1016\/S1053-4296(03)00031-6","journal-title":"Semin Radiat Oncol"},{"issue":"8","key":"11043_CR24","doi-asserted-by":"publisher","first-page":"1135","DOI":"10.1016\/j.ejca.2005.02.012","volume":"41","author":"TJ Postma","year":"2005","unstructured":"Postma TJ, Aaronson NK, Heimans JJ et al (2005) The development of an EORTC quality of life questionnaire to assess chemotherapy-induced peripheral neuropathy: the QLQ-CIPN20. Eur J Cancer 41(8):1135\u20131139. https:\/\/doi.org\/10.1016\/j.ejca.2005.02.012","journal-title":"Eur J Cancer"},{"issue":"5","key":"11043_CR25","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1093\/jnci\/85.5.365","volume":"85","author":"NK Aaronson","year":"1993","unstructured":"Aaronson NK, Ahmedzai S, Bergman B et al (1993) The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 85(5):365\u2013376. https:\/\/doi.org\/10.1093\/jnci\/85.5.365","journal-title":"J Natl Cancer Inst"},{"key":"11043_CR26","unstructured":"\u00d6ns\u00fcz \u00dc. (2015) Taksan Bazl\u0131 Tedavi Alan Kanser Hastalar\u0131nda Olu\u015fan Periferal N\u00f6ropatinin Y\u00f6netiminde Hastalar\u0131n Uygulad\u0131\u011f\u0131 Giri\u015fimlerin Etkinli\u011fi: \u0130stanbul University"},{"issue":"4","key":"11043_CR27","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1111\/jns.12660","volume":"29","author":"AG Zippo","year":"2024","unstructured":"Zippo AG, Rodriguez-Menendez V, Pozzi E et al (2024) Paclitaxel alters the microvascular network in the central and peripheral nervous system of rats with chemotherapy-induced painful peripheral neuropathy. J Peripher Nerv Syst 29(4):537\u2013554. https:\/\/doi.org\/10.1111\/jns.12660","journal-title":"J Peripher Nerv Syst"},{"key":"11043_CR28","doi-asserted-by":"publisher","unstructured":"Kacem H, Cimini A, d'Angelo M, et al. (2024) Molecular and Cellular Involvement in CIPN. Biomedicines. 12(4). https:\/\/doi.org\/10.3390\/biomedicines12040751","DOI":"10.3390\/biomedicines12040751"},{"key":"11043_CR29","doi-asserted-by":"publisher","DOI":"10.1007\/s00210-025-04480-6","author":"AG Naeem","year":"2025","unstructured":"Naeem AG, Fawzi SF, Elmorsi RM et al (2025) Paclitaxel-induced adverse effects: insights into multi-organ toxicities and molecular mechanisms. Naunyn Schmiedebergs Arch Pharmacol. https:\/\/doi.org\/10.1007\/s00210-025-04480-6","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"11043_CR30","doi-asserted-by":"publisher","DOI":"10.4274\/jcrpe.galenos.2025.2025-2-17","author":"G Akin Kagizmanli","year":"2025","unstructured":"Akin Kagizmanli G, Aydin T, YuksekAcinikli K et al (2025) Nailfold Capillaroscopy: A Non-Invasive Tool for Early Detection of Microvascular Alterations in Children with Type 1 Diabetes Mellitus. J Clin Res Pediatr Endocrinol. https:\/\/doi.org\/10.4274\/jcrpe.galenos.2025.2025-2-17","journal-title":"J Clin Res Pediatr Endocrinol"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-026-11043-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-026-11043-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-026-11043-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T03:23:27Z","timestamp":1786245807000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-026-11043-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,26]]},"references-count":30,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["11043"],"URL":"https:\/\/doi.org\/10.1007\/s00520-026-11043-9","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,26]]},"assertion":[{"value":"6 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"None.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"803"}}