{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T20:59:59Z","timestamp":1790369999935,"version":"4.1.0"},"reference-count":81,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universidade Federal Do Piau\u00ed","id":[{"id":"https:\/\/ror.org\/00kwnx126","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To discuss the main challenges in oral rehabilitation of patients with oral cancer after surgical resection and to present viable strategies to overcome these limitations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A comprehensive literature search was conducted and the principal clinically relevant challenges identified were reduced bone height, flap volume, glossectomy, limited mouth opening, velopharyngeal dysfunction, and xerostomia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Maxillary palatal ramp prostheses, mandibular guidance prostheses, and twin occlusion prostheses are indicated for patients without reconstruction grafting who present reduced bone height and mandibular deviation. In cases of extensive hard and soft tissue loss, type 3 fixed prostheses represent an appropriate option. Patients undergoing glossectomy may benefit from palatal or lingual augmentation and mandibular obturator prostheses. Sectional and flexible prostheses are suitable for individuals with restricted mouth opening. Maxillary or pharyngeal obturator prostheses are recommended for velopharyngeal dysfunction, while prostheses incorporating salivary reservoirs may assist patients with xerostomia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Oncologic treatment may result in multiple anatomical and functional oral alterations. Clinicians must be familiar with available prosthetic rehabilitation options to adequately manage these conditions. A multidisciplinary approach is essential to achieve effective and integrated care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical significance<\/jats:title>\n                    <jats:p>Presents practical, evidence-based alternatives to optimize function, comfort, and quality of life in patients with complex oral conditions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00520-026-11070-6","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T21:23:02Z","timestamp":1787174582000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Oral rehabilitation of patients with cancer: challenges following surgical resection"],"prefix":"10.1007","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3823-5759","authenticated-orcid":false,"given":"S\u00e9rvulo","family":"da Costa Rodrigues Neto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4481-4543","authenticated-orcid":false,"given":"Tha\u00eds Cristina Ara\u00fajo","family":"Moreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6365-8852","authenticated-orcid":false,"given":"Marta Maria Alves","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5393-9036","authenticated-orcid":false,"given":"Mila Oliveira Santos","family":"Viana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,19]]},"reference":[{"issue":"3","key":"11070_CR1","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3322\/caac.21834","volume":"74","author":"F Bray","year":"2022","unstructured":"Bray F, Laversanne M, Sung H et al (2022) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 74(3):229\u2013263. https:\/\/doi.org\/10.3322\/caac.21834","journal-title":"CA Cancer J Clin"},{"issue":"1","key":"11070_CR2","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1111\/idh.12051","volume":"12","author":"KA Moore","year":"2014","unstructured":"Moore KA, Ford PJ, Farah CS (2014) Support needs and quality of life in oral cancer: a systematic review. Int J Dent Hyg 12(1):36\u201347. https:\/\/doi.org\/10.1111\/idh.12051","journal-title":"Int J Dent Hyg"},{"issue":"1","key":"11070_CR3","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3322\/caac.21871","volume":"75","author":"RL Siegel","year":"2025","unstructured":"Siegel RL, Kratzer TB, Giaquinto AN, Sung H, Jemal A (2025) Cancer statistics, 2025. CA Cancer J Clin 75(1):10\u201345. https:\/\/doi.org\/10.3322\/caac.21871","journal-title":"CA Cancer J Clin"},{"issue":"2","key":"11070_CR4","doi-asserted-by":"publisher","first-page":"42","DOI":"10.3390\/medsci11020042","volume":"11","author":"A Barsouk","year":"2023","unstructured":"Barsouk A, Aluru JS, Rawla P, Saginala K, Barsouk A (2023) Epidemiology, risk factors, and prevention of head and neck squamous cell carcinoma. Med Sci (Basel) 11(2):42. https:\/\/doi.org\/10.3390\/medsci11020042","journal-title":"Med Sci (Basel)"},{"issue":"8","key":"11070_CR5","doi-asserted-by":"publisher","first-page":"1729","DOI":"10.1002\/jso.25075","volume":"117","author":"I Petrovic","year":"2018","unstructured":"Petrovic I, Rosen EB, Matros E, Huryn JM, Shah JP (2018) Oral rehabilitation of the cancer patient: a formidable challenge. J Surg Oncol 117(8):1729\u20131735. https:\/\/doi.org\/10.1002\/jso.25075","journal-title":"J Surg Oncol"},{"issue":"2","key":"11070_CR6","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.coms.2015.01.007","volume":"27","author":"P Boonsiriphant","year":"2015","unstructured":"Boonsiriphant P, Hirsch JA, Greenberg AM, Genden EM (2015) Prosthodontic considerations in post-cancer reconstructions. Oral Maxillofac Surg Clin North Am 27(2):255\u2013263. https:\/\/doi.org\/10.1016\/j.coms.2015.01.007","journal-title":"Oral Maxillofac Surg Clin North Am"},{"issue":"3","key":"11070_CR7","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.3390\/jcm12031122","volume":"12","author":"K Onodera","year":"2023","unstructured":"Onodera K, Miyamoto I, Hoshi I et al (2023) Towards optimum mandibular reconstruction for dental occlusal rehabilitation: from preoperative virtual surgery to autogenous particulate cancellous bone and marrow graft with custom-made titanium mesh-a retrospective study. J Clin Med 12(3):1122. https:\/\/doi.org\/10.3390\/jcm12031122","journal-title":"J Clin Med"},{"issue":"3","key":"11070_CR8","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1111\/cid.12912","volume":"22","author":"F Wiedenmann","year":"2020","unstructured":"Wiedenmann F, Liebermann A, Probst F et al (2020) A pattern of care analysis: prosthetic rehabilitation of head and neck cancer patients after radiotherapy. Clin Implant Dent Relat Res 22(3):333\u2013341. https:\/\/doi.org\/10.1111\/cid.12912","journal-title":"Clin Implant Dent Relat Res"},{"key":"11070_CR9","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-025-01861-x","volume-title":"Can prosthodontic rehabilitation support social eating and return to work in head and neck cancer survivors?","author":"A Brodeur","year":"2025","unstructured":"Brodeur A, Bach N, Zerbo A, Hovey R, Idrissi Janati A (2025) Can prosthodontic rehabilitation support social eating and return to work in head and neck cancer survivors? J Cancer Surviv, A scoping review. https:\/\/doi.org\/10.1007\/s11764-025-01861-x"},{"issue":"Suppl 1","key":"11070_CR10","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1007\/s12663-023-01883-x","volume":"22","author":"V Manju","year":"2023","unstructured":"Manju V, Krishnapriya VN, Babu AS, Krishnadas A, Subash P, Iyer S (2023) Prosthetic rehabilitation options in post-ablative maxillomandibular microvascular reconstructions. J Maxillofac Oral Surg 22(Suppl 1):10\u201319. https:\/\/doi.org\/10.1007\/s12663-023-01883-x","journal-title":"J Maxillofac Oral Surg"},{"issue":"12","key":"11070_CR11","doi-asserted-by":"publisher","first-page":"7121","DOI":"10.1007\/s00784-022-04673-w","volume":"26","author":"K Zierden","year":"2022","unstructured":"Zierden K, W\u00f6stmann J, W\u00f6stmann B, Rehmann P (2022) Clinical performance of different types of dental prosthesis in patients with head and neck tumors-a retrospective cohort study. Clin Oral Investig 26(12):7121\u20137133. https:\/\/doi.org\/10.1007\/s00784-022-04673-w","journal-title":"Clin Oral Investig"},{"issue":"1","key":"11070_CR12","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1111\/odi.13374","volume":"27","author":"N Vosselman","year":"2021","unstructured":"Vosselman N, Alberga J, Witjes MHJ, Raghoebar GM, Reintsema H, Vissink A, Korfage A (2021) Prosthodontic rehabilitation of head and neck cancer patients-challenges and new developments. Oral Dis 27(1):64\u201372. https:\/\/doi.org\/10.1111\/odi.13374","journal-title":"Oral Dis"},{"issue":"5","key":"11070_CR13","doi-asserted-by":"publisher","first-page":"960","DOI":"10.3390\/healthcare10050960.PMID:35628095;PMCID:PMC9140416","volume":"10","author":"Y Matsuda","year":"2022","unstructured":"Matsuda Y, Jayasinghe RD, Zhong H, Arakawa S, Kanno T (2022) Oral health management and rehabilitation for patients with oral cancer: a narrative review. Healthcare (Basel) 10(5):960. https:\/\/doi.org\/10.3390\/healthcare10050960","journal-title":"Healthcare (Basel)"},{"issue":"3","key":"11070_CR14","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1007\/s11912-024-01507-8","volume":"26","author":"M Florimond","year":"2024","unstructured":"Florimond M, Duong LT, Lours E et al (2024) Oral health in patients with history of head and neck cancer: complexity and benefits of a targeted oral healthcare pathway. Curr Oncol Rep 26(3):258\u2013271. https:\/\/doi.org\/10.1007\/s11912-024-01507-8","journal-title":"Curr Oncol Rep"},{"issue":"9","key":"11070_CR15","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.44647","volume":"15","author":"S Kumar","year":"2023","unstructured":"Kumar S, Dwivedi H, Singh B, Jha AK, Jain R, Singh S (2023) A systematic review on prosthodontic rehabilitation of hemimandibulectomy defects. Cureus 15(9):e44647. https:\/\/doi.org\/10.7759\/cureus.44647","journal-title":"Cureus"},{"issue":"2","key":"11070_CR16","doi-asserted-by":"publisher","first-page":"208","DOI":"10.4103\/0972-4052.164914","volume":"16","author":"AS Marathe","year":"2016","unstructured":"Marathe AS, Kshirsagar PS (2016) A systematic approach in rehabilitation of hemimandibulectomy: a case report. J Indian Prosthodont Soc 16(2):208\u201312. https:\/\/doi.org\/10.4103\/0972-4052.164914","journal-title":"J Indian Prosthodont Soc"},{"issue":"Suppl 1","key":"11070_CR17","doi-asserted-by":"publisher","first-page":"S111","DOI":"10.4103\/0976-237X.152961","volume":"6","author":"SR Bhattacharya","year":"2015","unstructured":"Bhattacharya SR, Majumdar D, Singh DK, Islam MD, Ray PK, Saha N (2015) Maxillary palatal ramp prosthesis: a prosthodontic solution to manage mandibular deviation following surgery. Contemp Clin Dent 6(Suppl 1):S111\u2013S113. https:\/\/doi.org\/10.4103\/0976-237X.152961","journal-title":"Contemp Clin Dent"},{"issue":"10","key":"11070_CR18","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.30132","volume":"14","author":"V Sharma","year":"2022","unstructured":"Sharma V, Paliwal J, Dadarwal A, Meena KK (2022) Guidance prostheses for partial mandibulectomy patients: a case series. Cureus 14(10):e30132. https:\/\/doi.org\/10.7759\/cureus.30132","journal-title":"Cureus"},{"issue":"2","key":"11070_CR19","doi-asserted-by":"publisher","first-page":"208","DOI":"10.4103\/jips.jips_12_21","volume":"21","author":"R Hazra","year":"2021","unstructured":"Hazra R, Srivastava A, Kumar D (2021) Mandibular guidance prosthesis: conventional and innovative approach: A case series. J Indian Prosthodont Soc 21(2):208\u2013214. https:\/\/doi.org\/10.4103\/jips.jips_12_21","journal-title":"J Indian Prosthodont Soc"},{"issue":"4","key":"11070_CR20","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1007\/s13191-011-0091-8","volume":"11","author":"S Agarwal","year":"2011","unstructured":"Agarwal S, Praveen G, Agarwal SK, Sharma S (2011) Twin occlusion: a solution to rehabilitate hemimandibulectomy patient-a case report. J Indian Prosthodont Soc 11(4):254\u2013257. https:\/\/doi.org\/10.1007\/s13191-011-0091-8","journal-title":"J Indian Prosthodont Soc"},{"issue":"2","key":"11070_CR21","doi-asserted-by":"publisher","first-page":"449","DOI":"10.4103\/0976-9668.160036","volume":"6","author":"PR Koralakunte","year":"2015","unstructured":"Koralakunte PR, Shamnur SN, Iynalli RV, Shivmurthy S (2015) Prosthetic management of hemimandibulectomy patient with guiding plane and twin occlusion prosthesis. J Nat Sci Biol Med 6(2):449\u2013453. https:\/\/doi.org\/10.4103\/0976-9668.160036","journal-title":"J Nat Sci Biol Med"},{"key":"11070_CR22","doi-asserted-by":"publisher","unstructured":"Adil H, Ahmed N, Heboyan A (2023) Prosthetic rehabilitation of a patient with hemimandibulectomy by a double occlusal table prosthesis. SAGE Open Med Case Rep 11:2050313X231181976. https:\/\/doi.org\/10.1177\/2050313X231181976","DOI":"10.1177\/2050313X231181976"},{"issue":"11","key":"11070_CR23","doi-asserted-by":"publisher","first-page":"1739","DOI":"10.1002\/ccr3.1125","volume":"5","author":"SK Sahu","year":"2017","unstructured":"Sahu SK, Motwani BK, Dani A (2017) Prosthetic rehabilitation of edentulous hemimandibulectomy patient: a clinical report. Clin Case Rep 5(11):1739\u20131742. https:\/\/doi.org\/10.1002\/ccr3.1125","journal-title":"Clin Case Rep"},{"key":"11070_CR24","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/475186","volume":"2013","author":"U Romeo","year":"2013","unstructured":"Romeo U, Lollobrigida M, Palaia G, Laurito D, Cugnetto R, De Biase A (2013) Soft tissue management and prosthetic rehabilitation in a tongue cancer patient. Case Rep Dent 2013:475186. https:\/\/doi.org\/10.1155\/2013\/475186","journal-title":"Case Rep Dent"},{"issue":"1","key":"11070_CR25","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1186\/s12903-019-0821-6","volume":"19","author":"A Abe","year":"2019","unstructured":"Abe A, Kurita K, Hayashi H, Ito Y (2019) Technique for secondary modification after maxillary resection and reconstruction for soft tissue flap fixation before prosthesis addition: a case report. BMC Oral Health 19(1):125. https:\/\/doi.org\/10.1186\/s12903-019-0821-6","journal-title":"BMC Oral Health"},{"issue":"7","key":"11070_CR26","doi-asserted-by":"publisher","first-page":"e41","DOI":"10.1016\/j.bjoms.2017.04.017","volume":"55","author":"G Tirelli","year":"2017","unstructured":"Tirelli G, Tofanelli M, Boscolo Nata F, Ramella V, Arne\u017e ZM (2017) Anchors for sutures to fix pedicled flaps to the floor of the mouth in reconstructions for cancer. Br J Oral Maxillofac Surg 55(7):e41\u2013e42. https:\/\/doi.org\/10.1016\/j.bjoms.2017.04.017","journal-title":"Br J Oral Maxillofac Surg"},{"issue":"8","key":"11070_CR27","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1016\/j.adaj.2019.04.015","volume":"150","author":"J Carpentieri","year":"2019","unstructured":"Carpentieri J, Greenstein G, Cavallaro J (2019) Hierarchy of restorative space required for different types of dental implant prostheses. J Am Dent Assoc 150(8):695\u2013706. https:\/\/doi.org\/10.1016\/j.adaj.2019.04.015","journal-title":"J Am Dent Assoc"},{"issue":"1","key":"11070_CR28","doi-asserted-by":"publisher","first-page":"146","DOI":"10.4103\/njms.NJMS_22_19","volume":"11","author":"H Kaur","year":"2020","unstructured":"Kaur H, Bhatia V, Singh M, Buragohain A (2020) Full-mouth rehabilitation of screw-retained maxillary and mandibular hybrid denture. Natl J Maxillofac Surg 11(1):146\u2013149. https:\/\/doi.org\/10.4103\/njms.NJMS_22_19","journal-title":"Natl J Maxillofac Surg"},{"key":"11070_CR29","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2024.110433","volume":"124","author":"S Akifuddin","year":"2024","unstructured":"Akifuddin S, Awadalkreem F (2024) Prosthetic rehabilitation of segmental mandibulectomy patient using a free fibula flap and Corticobasal implant supported prosthesis: a case report. Int J Surg Case Rep 124:110433. https:\/\/doi.org\/10.1016\/j.ijscr.2024.110433","journal-title":"Int J Surg Case Rep"},{"issue":"10","key":"11070_CR30","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1038\/s41415-019-0318-3","volume":"226","author":"S Nayar","year":"2019","unstructured":"Nayar S (2019) Current concepts and novel techniques in the prosthodontic management of head and neck cancer patients. Br Dent J 226(10):725\u2013737. https:\/\/doi.org\/10.1038\/s41415-019-0318-3","journal-title":"Br Dent J"},{"issue":"2","key":"11070_CR31","doi-asserted-by":"publisher","first-page":"190","DOI":"10.4103\/jips.jips_304_18","volume":"19","author":"PR Kumar","year":"2019","unstructured":"Kumar PR, Hasti A, Jagadeesh HG, Thoudam B (2019) Rehabilitation of a partial glossectomy patient: palatal augmentation prosthesis. J Indian Prosthodont Soc 19(2):190\u2013196. https:\/\/doi.org\/10.4103\/jips.jips_304_18","journal-title":"J Indian Prosthodont Soc"},{"issue":"7","key":"11070_CR32","doi-asserted-by":"publisher","DOI":"10.1002\/cnr2.1516","volume":"5","author":"I Kuniyuki","year":"2022","unstructured":"Kuniyuki I, Hisaoka T, Ikeda R et al (2022) Changes in tongue pressure and dysphagia at oral cancer patients by palatal augmentation prosthesis. Cancer Rep 5(7):e1516. https:\/\/doi.org\/10.1002\/cnr2.1516","journal-title":"Cancer Rep"},{"issue":"6","key":"11070_CR33","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1016\/j.prosdent.2016.08.025","volume":"117","author":"T Ohno","year":"2017","unstructured":"Ohno T, Fujishima I (2017) Palatal and lingual augmentation prosthesis for patients with dysphagia and functional problems: a clinical report. J Prosthet Dent 117(6):811\u2013813. https:\/\/doi.org\/10.1016\/j.prosdent.2016.08.025","journal-title":"J Prosthet Dent"},{"issue":"2","key":"11070_CR34","doi-asserted-by":"publisher","first-page":"ZE01","DOI":"10.7860\/JCDR\/2016\/15868.7184","volume":"10","author":"MK Balasubramaniam","year":"2016","unstructured":"Balasubramaniam MK, Chidambaranathan AS, Shanmugam G, Tah R (2016) Rehabilitation of glossectomy cases with tongue prosthesis: a literature review. J Clin Diagn Res 10(2):ZE01-4. https:\/\/doi.org\/10.7860\/JCDR\/2016\/15868.7184","journal-title":"J Clin Diagn Res"},{"issue":"3","key":"11070_CR35","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/s00520-025-09241-y","volume":"33","author":"II Artopoulou","year":"2025","unstructured":"Artopoulou II, Dereka X, Papalexopoulos D, Kouri M, Giannakopoulos NN (2025) Is palatal augmentation prosthesis effective in restoring speech, swallowing, and quality of life following cancer associated glossectomy? A systematic review. Support Care Cancer 33(3):215. https:\/\/doi.org\/10.1007\/s00520-025-09241-y","journal-title":"Support Care Cancer"},{"key":"11070_CR36","doi-asserted-by":"publisher","first-page":"6548014","DOI":"10.1155\/2016\/6548014","volume":"2016","author":"V Carvalho","year":"2016","unstructured":"Carvalho V, Sennes LU (2016) Speech and swallowing data in individual patients who underwent glossectomy after prosthetic rehabilitation. Int J Dent 2016:6548014. https:\/\/doi.org\/10.1155\/2016\/6548014","journal-title":"Int J Dent"},{"issue":"8","key":"11070_CR37","doi-asserted-by":"publisher","first-page":"1882","DOI":"10.1002\/hed.26124","volume":"42","author":"H L\u00f6fhede","year":"2020","unstructured":"L\u00f6fhede H, Werts\u00e9n M, Havstam C (2020) Palatal augmentation prostheses in individuals treated for head and neck cancer: effects on speech and oral transport. Head Neck 42(8):1882\u20131892. https:\/\/doi.org\/10.1002\/hed.26124","journal-title":"Head Neck"},{"issue":"8","key":"11070_CR38","doi-asserted-by":"publisher","first-page":"20230006","DOI":"10.2490\/prm.20230006","volume":"1","author":"M Hirasaki","year":"2023","unstructured":"Hirasaki M, Takagi D, Umeda Y, Moriwaki M, Katagiri N, Nomoto A, Ohno T, Fujishima I (2023) A case of dysphagia and dysarthria improved by flexible-palatal lift\/augmentation combination prosthesis. Prog Rehabil Med 1(8):20230006. https:\/\/doi.org\/10.2490\/prm.20230006","journal-title":"Prog Rehabil Med"},{"issue":"3","key":"11070_CR39","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1007\/s13191-010-0029-6","volume":"10","author":"GK Bachher","year":"2010","unstructured":"Bachher GK, Dholam KP (2010) Long term rehabilitation of a total glossectomy patient. J Indian Prosthodont Soc 10(3):194\u20136. https:\/\/doi.org\/10.1007\/s13191-010-0029-6","journal-title":"J Indian Prosthodont Soc"},{"issue":"5","key":"11070_CR40","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.prosdent.2007.03.009","volume":"97","author":"M Penn","year":"2007","unstructured":"Penn M, Grossmann Y, Shifman A, Taicher S (2007) Implant-retained feeding aid prosthesis for a patient following total glossectomy and laryngectomy: a clinical report. J Prosthet Dent 97(5):261\u2013265. https:\/\/doi.org\/10.1016\/j.prosdent.2007.03.009","journal-title":"J Prosthet Dent"},{"issue":"4","key":"11070_CR41","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1055\/s-0043-1772455","volume":"56","author":"K Jagtiani","year":"2023","unstructured":"Jagtiani K, Bhatia P, Jain R, Singh GP, Gurav S (2023) Prosthetic management of flap-related complications following glossectomy in locally advanced tongue cancer. Indian J Plast Surg 56(4):382\u2013385. https:\/\/doi.org\/10.1055\/s-0043-1772455","journal-title":"Indian J Plast Surg"},{"issue":"9","key":"11070_CR42","doi-asserted-by":"publisher","first-page":"2120","DOI":"10.1016\/j.bjps.2020.12.096","volume":"74","author":"MJW Khoo","year":"2021","unstructured":"Khoo MJW, Ooi ASH (2021) Management of postreconstructive head and neck salivary fistulae: a review of current practices. J Plast Reconstr Aesthet Surg 74(9):2120\u20132132. https:\/\/doi.org\/10.1016\/j.bjps.2020.12.096","journal-title":"J Plast Reconstr Aesthet Surg"},{"issue":"1","key":"11070_CR43","doi-asserted-by":"publisher","first-page":"74","DOI":"10.4103\/0976-237X.111597","volume":"4","author":"A Sharma","year":"2013","unstructured":"Sharma A, Arora P, Wazir SS (2013) Hinged and sectional complete dentures for restricted mouth opening: a case report and review. Contemp Clin Dent 4(1):74\u201377. https:\/\/doi.org\/10.4103\/0976-237X.111597","journal-title":"Contemp Clin Dent"},{"issue":"4","key":"11070_CR44","doi-asserted-by":"publisher","first-page":"508","DOI":"10.5005\/jp-journals-10024-2548","volume":"20","author":"S Patil","year":"2019","unstructured":"Patil S, Raj AT, Sarode SC et al (2019) Prosthetic rehabilitation of microstomia patients: a systematic review of published case reports and case series. J Contemp Dent Pract 20(4):508\u2013515","journal-title":"J Contemp Dent Pract"},{"issue":"2","key":"11070_CR45","doi-asserted-by":"publisher","first-page":"162","DOI":"10.4103\/1735-3327.280895","volume":"17","author":"SH Shams","year":"2020","unstructured":"Shams SH, Shams SS, Ghasemi E (2020) A sectional complete denture for microstomic patients. Dent Res J (Isfahan) 17(2):162\u2013166","journal-title":"Dent Res J (Isfahan)"},{"issue":"3","key":"11070_CR46","doi-asserted-by":"publisher","first-page":"38","DOI":"10.17096\/jiufd.17015","volume":"51","author":"T Celakil","year":"2017","unstructured":"Celakil T, Demir A, Keskin H (2017) Sectional mandibular complete denture for a total maxillectomy patient with trismus: a clinical report. J Istanb Univ Fac Dent 51(3):38\u201344. https:\/\/doi.org\/10.17096\/jiufd.17015","journal-title":"J Istanb Univ Fac Dent"},{"issue":"3","key":"11070_CR47","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1007\/s13191-013-0263-9","volume":"13","author":"M Gauri","year":"2013","unstructured":"Gauri M, Ramandeep D (2013) Prosthodontic management of a completely edentulous patient with microstomia: a case report. J Indian Prosthodont Soc 13(3):338\u201342. https:\/\/doi.org\/10.1007\/s13191-013-0263-9","journal-title":"J Indian Prosthodont Soc"},{"issue":"1","key":"11070_CR48","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/s0022-3913(99)70135-6","volume":"82","author":"AC Cheng","year":"1999","unstructured":"Cheng AC, Wee AG, Morrison D, Maxymiw WG (1999) Hinged mandibular removable complete denture for post-mandibulectomy patients. J Prosthet Dent 82(1):103\u2013106. https:\/\/doi.org\/10.1016\/s0022-3913(99)70135-6","journal-title":"J Prosthet Dent"},{"issue":"4","key":"11070_CR49","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1111\/j.1754-4505.2012.00256.x","volume":"32","author":"JG Egan","year":"2012","unstructured":"Egan JG, Swindells SA (2012) A novel prosthodontic alternative for patients who are edentulous and have microstomia: a case report. Spec Care Dentist 32(4):160\u20134. https:\/\/doi.org\/10.1111\/j.1754-4505.2012.00256.x","journal-title":"Spec Care Dentist"},{"issue":"3","key":"11070_CR50","first-page":"60","volume":"2","author":"J Gandhimathi","year":"2015","unstructured":"Gandhimathi J, Krishnameera N, Sriramaprabu G, Vinayagavel K, Sabarigirinathan C, Rupkumar P, Sivasakthikumar S, Srividya S, Sangeethameena N (2015) A systematic approach for functional rehabilitation of hemimandibulectomy patient. Int J Oral Health Med Res 2(3):60\u201362","journal-title":"Int J Oral Health Med Res"},{"issue":"1","key":"11070_CR51","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1055\/s-0039-1697813","volume":"4","author":"SH Tuna","year":"2010","unstructured":"Tuna SH, Pekkan G, Gumus HO, Aktas A (2010) Prosthetic rehabilitation of velopharyngeal insufficiency: pharyngeal obturator prostheses with different retention mechanisms. Eur J Dent 4(1):81\u20137","journal-title":"Eur J Dent"},{"issue":"3","key":"11070_CR52","doi-asserted-by":"publisher","first-page":"249","DOI":"10.4103\/jips.jips_98_21","volume":"21","author":"R Grover","year":"2021","unstructured":"Grover R, Jurel SK, Agarwal B et al (2021) Speech intelligibility, nasal resonance, and swallowing ability of maxillectomy patients with customized obturator: a non randomized controlled study. J Indian Prosthodont Soc 21(3):249\u2013255. https:\/\/doi.org\/10.4103\/jips.jips_98_21","journal-title":"J Indian Prosthodont Soc"},{"key":"11070_CR53","doi-asserted-by":"publisher","first-page":"bcr2013008892","DOI":"10.1136\/bcr-2013-008892","volume":"2013","author":"YG Naveen","year":"2013","unstructured":"Naveen YG, Jagadeesh MS, Prajapati P, Mallikarjuna R (2013) Complete denture with pharyngeal bulb prosthesis. BMJ Case Rep 2013:bcr2013008892. https:\/\/doi.org\/10.1136\/bcr-2013-008892","journal-title":"BMJ Case Rep"},{"issue":"3","key":"11070_CR54","doi-asserted-by":"publisher","first-page":"281","DOI":"10.4103\/0972-4052.161573","volume":"15","author":"A Nanda","year":"2015","unstructured":"Nanda A, Koli D, Sharma S, Suryavanshi S, Verma M (2015) Alleviating speech and deglutition: role of a prosthodontist in multidisciplinary management of velopharyngeal insufficiency. J Indian Prosthodont Soc 15(3):281\u20133. https:\/\/doi.org\/10.4103\/0972-4052.161573","journal-title":"J Indian Prosthodont Soc"},{"issue":"23","key":"11070_CR55","doi-asserted-by":"publisher","first-page":"12524","DOI":"10.3390\/ijerph182312524","volume":"18","author":"M Corsalini","year":"2021","unstructured":"Corsalini M, Barile G, Catapano S, Ciocia A, Casorelli A, Siciliani R, Di Venere D, Capodiferro S (2021) Obturator prosthesis rehabilitation after maxillectomy: functional and aesthetical analysis in 25 patients. Int J Environ Res Public Health 18(23):12524. https:\/\/doi.org\/10.3390\/ijerph182312524","journal-title":"Int J Environ Res Public Health"},{"issue":"3","key":"11070_CR56","doi-asserted-by":"publisher","first-page":"283","DOI":"10.7860\/JCDR\/2014\/6220.4188","volume":"8","author":"NB Shetty","year":"2014","unstructured":"Shetty NB, Shetty S, D\u2019Souza R, Shetty O (2014) Management of velopharyngeal defects: a review. J Clin Diagn Res 8(3):283\u20137. https:\/\/doi.org\/10.7860\/JCDR\/2014\/6220.4188","journal-title":"J Clin Diagn Res"},{"issue":"4","key":"11070_CR57","doi-asserted-by":"publisher","first-page":"406","DOI":"10.4103\/jips.jips_106_17","volume":"17","author":"G Michelinakis","year":"2017","unstructured":"Michelinakis G (2017) The use of cone beam computed tomography and three dimensional printing technology in the restoration of a maxillectomy patient using a dental implant retained obturator. J Indian Prosthodont Soc 17(4):406\u2013411. https:\/\/doi.org\/10.4103\/jips.jips_106_17","journal-title":"J Indian Prosthodont Soc"},{"issue":"1","key":"11070_CR58","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.prosdent.2023.11.023","volume":"133","author":"J K\u00f6nig","year":"2025","unstructured":"K\u00f6nig J, Kelemen K, V\u00e1ncsa S, Szab\u00f3 B, Varga G, Mikul\u00e1s K, Borb\u00e9ly J, Hegyi P, Hermann P (2025) Comparative analysis of surgical and prosthetic rehabilitation in maxillectomy: a systematic review and meta-analysis on quality-of-life scores and objective speech and masticatory measurements. J Prosthet Dent 133(1):305\u2013314. https:\/\/doi.org\/10.1016\/j.prosdent.2023.11.023","journal-title":"J Prosthet Dent"},{"key":"11070_CR59","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/j.oraloncology.2018.05.019","volume":"82","author":"Y Cao","year":"2018","unstructured":"Cao Y, Yu C, Liu W, Miao C, Han B, Yang J, Li L, Li C (2018) Obturators versus flaps after maxillary oncological ablation: a systematic review and best evidence synthesis. Oral Oncol 82:152\u2013161. https:\/\/doi.org\/10.1016\/j.oraloncology.2018.05.019","journal-title":"Oral Oncol"},{"issue":"4","key":"11070_CR60","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/j.bjoms.2018.03.001","volume":"56","author":"DM Dos Santos","year":"2018","unstructured":"Dos Santos DM, de Caxias FP, Bitencourt SB, Turcio KH, Pesqueira AA, Goiato MC (2018) Oral rehabilitation of patients after maxillectomy. A systematic review. J Oral Maxillofac Surg 56(4):256\u2013266. https:\/\/doi.org\/10.1016\/j.bjoms.2018.03.001","journal-title":"J Oral Maxillofac Surg"},{"issue":"2","key":"11070_CR61","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-2358.2011.00519.x","volume":"29","author":"Y Singh","year":"2012","unstructured":"Singh Y, Saini M, Siwach A, Mittal R (2012) Management of a post-radiotherapy xerostomic patient--a case report. Gerodontology 29(2):e1172-5. https:\/\/doi.org\/10.1111\/j.1741-2358.2011.00519.x","journal-title":"Gerodontology"},{"issue":"1","key":"11070_CR62","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1007\/s13191-011-0096-3","volume":"12","author":"RB Hallikerimath","year":"2012","unstructured":"Hallikerimath RB, Jain M (2012) Managing the edentulous dry mouth: the two part mandibular denture. J Indian Prosthodont Soc 12(1):51\u201354. https:\/\/doi.org\/10.1007\/s13191-011-0096-3","journal-title":"J Indian Prosthodont Soc"},{"issue":"3","key":"11070_CR63","doi-asserted-by":"publisher","first-page":"693","DOI":"10.4103\/jcrt.JCRT_851_18","volume":"16","author":"S Srivastava","year":"2020","unstructured":"Srivastava S, Negi P, Chopra D, Misra S (2020) Maxillary reservoir denture to overcome radiation-induced xerostomia - light at the end of the tunnel. J Cancer Res Ther 16(3):693\u2013696. https:\/\/doi.org\/10.4103\/jcrt.JCRT_851_18","journal-title":"J Cancer Res Ther"},{"key":"11070_CR64","doi-asserted-by":"publisher","first-page":"8905891","DOI":"10.1155\/2016\/8905891","volume":"2016","author":"H Gurkar","year":"2016","unstructured":"Gurkar H, Venkatesh OY, Somashekar JM, Gowda MH, Dwivedi M, Ningthoujam I (2016) Prosthodontic management of xerostomic patient: a technical modification. Case Rep Dent 2016:8905891. https:\/\/doi.org\/10.1155\/2016\/8905891","journal-title":"Case Rep Dent"},{"issue":"12","key":"11070_CR65","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1002\/ccr3.640","volume":"4","author":"AM Joseph","year":"2016","unstructured":"Joseph AM, Joseph S, Mathew N, Koshy AT (2016) Functional salivary reservoir in maxillary complete denture - technique redefined. Clin Case Rep 4(12):1082\u20131087. https:\/\/doi.org\/10.1002\/ccr3.640","journal-title":"Clin Case Rep"},{"issue":"Suppl 1","key":"11070_CR66","doi-asserted-by":"publisher","first-page":"S190","DOI":"10.1016\/j.mjafi.2012.03.001","volume":"71","author":"K Verma","year":"2015","unstructured":"Verma K, Gowda EM, Pawar VR, Kalra A (2015) Salivary reservoir denture - a novel approach to battle xerostomia. Med J Armed Forces Indi 71(Suppl 1):S190-3. https:\/\/doi.org\/10.1016\/j.mjafi.2012.03.001","journal-title":"Med J Armed Forces Indi"},{"key":"11070_CR67","doi-asserted-by":"publisher","first-page":"bcr1120115250","DOI":"10.1136\/bcr.11.2011.5250","volume":"2012","author":"V Murthy","year":"2012","unstructured":"Murthy V, Yuvraj V, Nair PP, Thomas S (2012) Prosthodontic management of radiation induced xerostomic patient using flexible dentures. BMJ Case Rep 2012:bcr1120115250","journal-title":"BMJ Case Rep"},{"issue":"2","key":"11070_CR68","doi-asserted-by":"publisher","first-page":"271","DOI":"10.4103\/2141-9248.129062","volume":"4","author":"R Ladda","year":"2014","unstructured":"Ladda R, Kasat V, Gangadhar S, Baheti S, Bhandari A (2014) Reservoir complete denture in a patient with xerostomia secondary to radiotherapy for oral carcinoma: a case report and review of literature. Ann Med Health Sci Res 4(2):271\u2013275. https:\/\/doi.org\/10.4103\/2141-9248.129062","journal-title":"Ann Med Health Sci Res"},{"issue":"10","key":"11070_CR69","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.95691","volume":"17","author":"MA Dodia","year":"2025","unstructured":"Dodia MA, Patel N, Desai C, Chakraborty B (2025) Comparative evaluation of conventional and digital techniques for maxillofacial prosthesis fabrication: a systematic review of the literature. Cureus 17(10):e95691. https:\/\/doi.org\/10.7759\/cureus.95691","journal-title":"Cureus"},{"issue":"83","key":"11070_CR70","doi-asserted-by":"publisher","first-page":"392","DOI":"10.2340\/aos.v83.40870","volume":"19","author":"G Srivastava","year":"2024","unstructured":"Srivastava G, Padhiary SK, Mohanty N, Patil PG, Panda S, Cobo-Vazquez C, \u00c7akmak G, Molinero-Mourelle P (2024) Digital workflow feasibility for the fabrication of intraoral maxillofacial prosthetics after surgical resection: a systematic literature review. Acta Odontol Scand 19(83):392\u2013403. https:\/\/doi.org\/10.2340\/aos.v83.40870","journal-title":"Acta Odontol Scand"},{"issue":"6","key":"11070_CR71","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1563\/aaid-joi-D-24-00115","volume":"50","author":"S Xu","year":"2024","unstructured":"Xu S, Lv J, Zhou Y, Wang K (2024) Utilizing a fully digital approach for oral squamous cell carcinoma treatment and zygomatic implant-based rehabilitation for maxillary defects. J Oral Implantol 50(6):595\u2013604. https:\/\/doi.org\/10.1563\/aaid-joi-D-24-00115","journal-title":"J Oral Implantol"},{"issue":"3","key":"11070_CR72","doi-asserted-by":"publisher","first-page":"266","DOI":"10.4103\/jips.jips_64_25","volume":"25","author":"G Chouksey","year":"2025","unstructured":"Chouksey G, Singh GP, Gupta V, Sahoo P, Choure R, Goyal A (2025) A pilot study comparing conventional and digital impression techniques for speech analysis using Hindi vowels in maxillectomy patients rehabilitated with an obturator. J Indian Prosthodont Soc 25(3):266\u2013275. https:\/\/doi.org\/10.4103\/jips.jips_64_25","journal-title":"J Indian Prosthodont Soc"},{"issue":"1","key":"11070_CR73","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1007\/s10006-025-01379-7","volume":"29","author":"G De Riu","year":"2025","unstructured":"De Riu G, Biglio A, Baj A, Maniaci A, Lechien JR, Vaira LA (2025) Primary reconstruction of total maxillectomy defect with additively manufactured subperiosteal implant and fibula free flap: a case report. Oral Maxillofac Surg 29(1):86. https:\/\/doi.org\/10.1007\/s10006-025-01379-7","journal-title":"Oral Maxillofac Surg"},{"issue":"1","key":"11070_CR74","doi-asserted-by":"publisher","first-page":"151","DOI":"10.3390\/medicina62010151","volume":"62","author":"M Tousidonis","year":"2026","unstructured":"Tousidonis M, Salmeron JI, Ochandiano S, Perez-Ma\u00f1anes R, Gomez-Larren E, Aguilera-Jimenez E, de Gregorio-Bermejo C, Fern\u00e1ndez-Acosta D, Gonzalez-Moure B, Khayat S, Navarro-Cuellar C (2026) Guided implant surgery in oral cancer patients: initial clinical experience from an academic point-of-care manufacturing unit. Medicina (Kaunas) 62(1):151. https:\/\/doi.org\/10.3390\/medicina62010151","journal-title":"Medicina (Kaunas)"},{"issue":"11","key":"11070_CR75","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.754943","volume":"28","author":"S Ochandiano","year":"2022","unstructured":"Ochandiano S, Garc\u00eda-Mato D, Gonzalez-Alvarez A, Moreta-Martinez R, Tousidonis M, Navarro-Cuellar C, Navarro-Cuellar I, Salmer\u00f3n JI, Pascau J (2022) Computer-assisted dental implant placement following free flap reconstruction: virtual planning, CAD\/CAM templates, dynamic navigation and augmented reality. Front Oncol 28(11):754943. https:\/\/doi.org\/10.3389\/fonc.2021.754943","journal-title":"Front Oncol"},{"issue":"12","key":"11070_CR76","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1007\/s00520-023-08088-5","volume":"31","author":"GCV Camolesi","year":"2023","unstructured":"Camolesi GCV, Veronese HRM, Celestino MA, Blum DFC, M\u00e1rquez-Zambrano JA, Carmona-P\u00e9rez FA, Jara-Venegas TA, Pellizzon ACA, Bernaola-Paredes WE (2023) Survival of osseointegrated implants in head and neck cancer patients submitted to multimodal treatment: a systematic review and meta-analysis. Support Care Cancer 31(12):641. https:\/\/doi.org\/10.1007\/s00520-023-08088-5","journal-title":"Support Care Cancer"},{"issue":"10","key":"11070_CR77","doi-asserted-by":"publisher","first-page":"5579","DOI":"10.1007\/s00784-021-04065-6","volume":"25","author":"DJ Toneatti","year":"2021","unstructured":"Toneatti DJ, Graf RR, Burkhard JP, Schaller B (2021) Survival of dental implants and occurrence of osteoradionecrosis in irradiated head and neck cancer patients: a systematic review and meta-analysis. Clin Oral Investig 25(10):5579\u20135593. https:\/\/doi.org\/10.1007\/s00784-021-04065-6","journal-title":"Clin Oral Investig"},{"issue":"7","key":"11070_CR78","doi-asserted-by":"publisher","first-page":"2767","DOI":"10.3390\/jcm15072767","volume":"15","author":"SX Chen","year":"2026","unstructured":"Chen SX, Feucht M, Bhatt A, Farlow JL (2026) Artificial intelligence in head and neck surgical oncology: a state-of-the-art review. J Clin Med 15(7):2767. https:\/\/doi.org\/10.3390\/jcm15072767","journal-title":"J Clin Med"},{"issue":"1","key":"11070_CR79","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1186\/s12903-019-0853-y","volume":"19","author":"G Pellegrino","year":"2019","unstructured":"Pellegrino G, Mangano C, Mangano R, Ferri A, Taraschi V, Marchetti C (2019) Augmented reality for dental implantology: a pilot clinical report of two cases. BMC Oral Health 19(1):158. https:\/\/doi.org\/10.1186\/s12903-019-0853-y","journal-title":"BMC Oral Health"},{"issue":"1","key":"11070_CR80","doi-asserted-by":"publisher","DOI":"10.1002\/osi2.1277","volume":"22","author":"TS Biju","year":"2025","unstructured":"Biju TS, Veeraraghavan VP, Francis AP (2025) Theranostic potential of miRNAs in oral cancer: an emerging approach for precision oncology. Oral Sci Int 22(1):e1277. https:\/\/doi.org\/10.1002\/osi2.1277","journal-title":"Oral Sci Int"},{"issue":"4","key":"11070_CR81","doi-asserted-by":"publisher","DOI":"10.2174\/0122103155351726250123083250","volume":"16","author":"S Chandra","year":"2026","unstructured":"Chandra S, Veeraraghavan VP, Woon CK, Sirasanagandla SR, Jayaraman S (2026) Mechanistic overview on therapeutic potential of phenols targeting the breast cancer: molecular insights and future road to drug design. Nat Prod J 16(4):e22103155351726. https:\/\/doi.org\/10.2174\/0122103155351726250123083250","journal-title":"Nat Prod J"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-026-11070-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-026-11070-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-026-11070-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T20:07:24Z","timestamp":1790366844000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00520-026-11070-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,19]]},"references-count":81,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["11070"],"URL":"https:\/\/doi.org\/10.1007\/s00520-026-11070-6","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,19]]},"assertion":[{"value":"24 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 August 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 August 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All procedures performed were in accordance with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":1,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"876"}}