{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T18:46:26Z","timestamp":1792089986050,"version":"4.4.0"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Support Care Cancer"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1007\/s00520-026-11229-1","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:46:18Z","timestamp":1790675178000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Heart rate variability suppression in cancer patients versus non-cancer controls: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"34","author":[{"given":"Hsiu-Hua","family":"Shih","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsu-Chieh","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Huang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia-Lun","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeu-Hui","family":"Chuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Hung","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Made Satya Nugraha","family":"Gautama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6722-1153","authenticated-orcid":false,"given":"Tsai-Wei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"11229_CR1","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","volume":"71","author":"H Sung","year":"2021","unstructured":"Sung H, Ferlay J, Siegel RL et al (2021) Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71:209\u2013249. https:\/\/doi.org\/10.3322\/caac.21660","journal-title":"CA Cancer J Clin"},{"key":"11229_CR2","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1161\/01.CIR.93.5.1043","volume":"93","author":"Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology","year":"1996","unstructured":"Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology (1996) Heart rate variability: standards of measurement, physiological interpretation and clinical use. Circulation 93:1043\u20131065. https:\/\/doi.org\/10.1161\/01.CIR.93.5.1043","journal-title":"Circulation"},{"key":"11229_CR3","doi-asserted-by":"publisher","first-page":"623","DOI":"10.3389\/fphys.2018.00623","volume":"9","author":"S Palma","year":"2018","unstructured":"Palma S, Hern\u00e1ndez-Jim\u00e9nez E, Malpartida-Arrieta FJ et al (2018) Heart rate variability as a prognostic factor for cancer survival\u2014a systematic review. Front Physiol 9:623. https:\/\/doi.org\/10.3389\/fphys.2018.00623","journal-title":"Front Physiol"},{"key":"11229_CR4","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.jpsychores.2016.08.004","volume":"89","author":"X Zhou","year":"2016","unstructured":"Zhou X, Ma Z, Zhang L et al (2016) Heart rate variability in the prediction of survival in patients with cancer: a systematic review and meta-analysis. J Psychosom Res 89:20\u201325. https:\/\/doi.org\/10.1016\/j.jpsychores.2016.08.004","journal-title":"J Psychosom Res"},{"key":"11229_CR5","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.660860","volume":"12","author":"C Fiuza-Luces","year":"2021","unstructured":"Fiuza-Luces C, S\u00e1nchez-Pino MJ, Rodr\u00edguez-Gonz\u00e1lez P et al (2021) Can exercise reduce the autonomic dysfunction of patients with cancer and its survivors? A systematic review and meta-analysis. Front Physiol 12:660860. https:\/\/doi.org\/10.3389\/fphys.2021.660860","journal-title":"Front Physiol"},{"key":"11229_CR6","volume-title":"Cochrane handbook for systematic reviews of interventions (version 6.5)","author":"JPT Higgins","year":"2024","unstructured":"Higgins JPT, Thomas J, Chandler J (2024) Cochrane handbook for systematic reviews of interventions (version 6.5). Cochrane"},{"key":"11229_CR7","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71","volume":"372","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM et al (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71. https:\/\/doi.org\/10.1136\/bmj.n71","journal-title":"BMJ"},{"key":"11229_CR8","unstructured":"Wells GA, Shea B, O'Connell D, Peterson J, Welch V, Losos M, Tugwell P (2011) The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Ottawa Hospital Research Institute. Available from: http:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp"},{"key":"11229_CR9","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.jpainsymman.2009.06.014","volume":"39","author":"N Fadul","year":"2010","unstructured":"Fadul N, Strasser F, Palmer JL et al (2010) The association between autonomic dysfunction and survival in male patients with advanced cancer: a preliminary report. J Pain Symptom Manage 39:283\u2013290. https:\/\/doi.org\/10.1016\/j.jpainsymman.2009.06.014","journal-title":"J Pain Symptom Manage"},{"key":"11229_CR10","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1111\/ecc.12066","volume":"22","author":"Y Guo","year":"2013","unstructured":"Guo Y, Palmer JL, Strasser F et al (2013) Heart rate variability as a measure of autonomic dysfunction in men with advanced cancer. Eur J Cancer Care (Engl) 22:612\u2013616. https:\/\/doi.org\/10.1111\/ecc.12066","journal-title":"Eur J Cancer Care (Engl)"},{"key":"11229_CR11","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1016\/j.jclinepi.2010.09.011","volume":"64","author":"GH Guyatt","year":"2011","unstructured":"Guyatt GH, Oxman AD, Sch\u00fcnemann HJ et al (2011) GRADE guidelines: a new series of articles in the Journal of Clinical Epidemiology. J Clin Epidemiol 64:380\u2013382. https:\/\/doi.org\/10.1016\/j.jclinepi.2010.09.011","journal-title":"J Clin Epidemiol"},{"key":"11229_CR12","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1111\/j.1542-474X.2005.10101.x","volume":"10","author":"RE Kleiger","year":"2005","unstructured":"Kleiger RE, Stein PK, Bigger JT Jr. (2005) Heart rate variability: measurement and clinical utility. Ann Noninvasive Electrocardiol 10:88\u2013101. https:\/\/doi.org\/10.1111\/j.1542-474X.2005.10101.x","journal-title":"Ann Noninvasive Electrocardiol"},{"key":"11229_CR13","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1186\/s13643-023-02217-1","volume":"12","author":"KY Chi","year":"2023","unstructured":"Chi KY, Li MY, Chen C et al (2023) Ten circumstances and solutions for finding the sample mean and standard deviation for meta-analysis. Syst Rev 12:62. https:\/\/doi.org\/10.1186\/s13643-023-02217-1","journal-title":"Syst Rev"},{"key":"11229_CR14","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1177\/1099800414568100","volume":"18","author":"E Caro-Mor\u00e1n","year":"2016","unstructured":"Caro-Mor\u00e1n E, Fern\u00e1ndez-Lao C, Galiano-Castillo N et al (2016) Heart rate variability in breast cancer survivors after the first year of treatments: a case-controlled study. Biol Res Nurs 18:43\u201349. https:\/\/doi.org\/10.1177\/1099800414568100","journal-title":"Biol Res Nurs"},{"key":"11229_CR15","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.46773","volume":"15","author":"E Khandelwal","year":"2023","unstructured":"Khandelwal E, Tripathi S, Gupta A, Singh A (2023) Profile of cardiovascular autonomic dysfunctions in breast cancer patients. Cureus 15:e46773. https:\/\/doi.org\/10.7759\/cureus.46773","journal-title":"Cureus"},{"key":"11229_CR16","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10194391","volume":"10","author":"K Vargas-Rom\u00e1n","year":"2021","unstructured":"Vargas-Rom\u00e1n K, Cort\u00e9s-Mart\u00edn J, S\u00e1nchez-Garc\u00eda JC et al (2021) Autonomic imbalance in lymphoma survivors. J Clin Med 10:4391. https:\/\/doi.org\/10.3390\/jcm10194391","journal-title":"J Clin Med"},{"key":"11229_CR17","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-01779-1","volume":"11","author":"M Vigier","year":"2021","unstructured":"Vigier M, Vigier B, Andritsch E, Schwerdtfeger AR (2021) Cancer classification using machine learning and HRV analysis: preliminary evidence from a pilot study. Sci Rep 11:22292. https:\/\/doi.org\/10.1038\/s41598-021-01779-1","journal-title":"Sci Rep"},{"key":"11229_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2023.102399","volume":"66","author":"SSS Wong","year":"2023","unstructured":"Wong SSS, Liu TW, Ng SSM (2023) Performance of physical, cardiovascular, and psychological functions in middle-aged women with and without breast cancer. Eur J Oncol Nurs 66:102399. https:\/\/doi.org\/10.1016\/j.ejon.2023.102399","journal-title":"Eur J Oncol Nurs"},{"key":"11229_CR19","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1007\/s11764-015-0445-z","volume":"9","author":"C Vigo","year":"2015","unstructured":"Vigo C, Gatzemeier W, Sala R et al (2015) Evidence of altered autonomic cardiac regulation in breast cancer survivors. J Cancer Surviv 9:699\u2013706. https:\/\/doi.org\/10.1007\/s11764-015-0445-z","journal-title":"J Cancer Surviv"},{"key":"11229_CR20","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-93713-8","volume":"11","author":"D Escutia-Reyes","year":"2021","unstructured":"Escutia-Reyes D, de Jes\u00fas Gardu\u00f1o-Garc\u00eda J, Emilio-L\u00f3pez-Ch\u00e1vez G et al (2021) Differences in heart rate variability and body composition in breast cancer survivors and women without cancer. Sci Rep 11:14460. https:\/\/doi.org\/10.1038\/s41598-021-93713-8","journal-title":"Sci Rep"},{"key":"11229_CR21","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1038\/bmt.2016.176","volume":"52","author":"G Deuring","year":"2016","unstructured":"Deuring G, Kiss A, Halter JP et al (2016) Cardiac autonomic functioning is impaired among allogeneic hematopoietic stem cell transplantation survivors: a controlled study. Bone Marrow Transplant 52:66\u201372. https:\/\/doi.org\/10.1038\/bmt.2016.176","journal-title":"Bone Marrow Transplant"},{"key":"11229_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2024.102587","volume":"70","author":"TL Chou","year":"2024","unstructured":"Chou TL, Shih CH, Chou PC et al (2024) Use of a wearable device to compare subjective and objective fatigue in lung cancer patients and cancer-free controls. Eur J Oncol Nurs 70:102587. https:\/\/doi.org\/10.1016\/j.ejon.2024.102587","journal-title":"Eur J Oncol Nurs"},{"key":"11229_CR23","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16050962","volume":"16","author":"K Ben-David","year":"2024","unstructured":"Ben-David K, Wittels HL, Wishon MJ et al (2024) Tracking cancer: exploring heart rate variability patterns by cancer location and progression. Cancers 16:962. https:\/\/doi.org\/10.3390\/cancers16050962","journal-title":"Cancers"},{"key":"11229_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e34453","volume":"10","author":"I Mikolaskova","year":"2024","unstructured":"Mikolaskova I, Zvarik M, Hesko P et al (2024) Increased stress burden and electrodermal reactivity in bladder cancer patients in comparison to healthy controls. Heliyon 10:e34453. https:\/\/doi.org\/10.1016\/j.heliyon.2024.e34453","journal-title":"Heliyon"},{"key":"11229_CR25","doi-asserted-by":"publisher","unstructured":"Petrescu M, Udristoiu I, Militaru F et al (2023) The assessment of heart rate variability in patients with pancreatic cancer. Curr Health Sci J 49:172\u2013178. https:\/\/doi.org\/10.12865\/chsj.49.02.172","DOI":"10.12865\/chsj.49.02.172"},{"key":"11229_CR26","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1186\/s13014-023-02362-w","volume":"18","author":"M Aoki","year":"2023","unstructured":"Aoki M, Kuratsune H, Yamamoto S et al (2023) Autonomic function measurements for evaluating fatigue and quality of life in patients with breast cancer undergoing radiation therapy: a prospective longitudinal study. Radiat Oncol 18:171. https:\/\/doi.org\/10.1186\/s13014-023-02362-w","journal-title":"Radiat Oncol"},{"key":"11229_CR27","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.psyneuen.2014.03.011","volume":"45","author":"AD Crosswell","year":"2014","unstructured":"Crosswell AD, Lockwood KG, Ganz PA, Bower JE (2014) Low heart rate variability and cancer-related fatigue in breast cancer survivors. Psychoneuroendocrinology 45:58\u201366. https:\/\/doi.org\/10.1016\/j.psyneuen.2014.03.011","journal-title":"Psychoneuroendocrinology"},{"key":"11229_CR28","doi-asserted-by":"publisher","unstructured":"Fagundes CP, Murray DM, Hwang BS, et al (2011) Sympathetic and parasympathetic activity in cancer-related fatigue: more evidence for a physiological substrate in cancer survivors. Psychoneuroendocrinology 36:1137\u20131147. https:\/\/doi.org\/10.1016\/j.psyneuen.2011.02.005","DOI":"10.1016\/j.psyneuen.2011.02.005"},{"key":"11229_CR29","doi-asserted-by":"publisher","unstructured":"Farbood A, Sahmeddini MA, Bayat S, Karami N\u00a0(2020) The effect of preoperative depression and anxiety on heart rate variability in women with breast cancer. Breast Cancer 27(5):912\u2013918. https:\/\/doi.org\/10.1007\/s12282-020-01087-y","DOI":"10.1007\/s12282-020-01087-y"},{"key":"11229_CR30","doi-asserted-by":"publisher","unstructured":"Guimond AJ, Ivers H, Savard J (2019) Is emotion regulation associated with cancer-related psychological symptoms? Psychol Health 34:44\u201363. https:\/\/doi.org\/10.1080\/08870446.2018.1514462","DOI":"10.1080\/08870446.2018.1514462"},{"key":"11229_CR31","doi-asserted-by":"publisher","unstructured":"Hansen MV, Rosenberg J, G\u00f8genur I (2013) Lack of circadian variation and reduction of heart rate variability in women with breast cancer undergoing lumpectomy: a descriptive study. Breast Cancer Res Treat 140:317\u2013322. https:\/\/doi.org\/10.1007\/s10549-013-2631-x","DOI":"10.1007\/s10549-013-2631-x"},{"key":"11229_CR32","doi-asserted-by":"publisher","unstructured":"Harel K, Czamanski-Cohen J, Cohen M et al (2025) Cardiac vagal control and emotional awareness associated with pain among breast cancer survivors. Psychophysiology 62:e70086. https:\/\/doi.org\/10.1111\/psyp.70086","DOI":"10.1111\/psyp.70086"},{"key":"11229_CR33","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1186\/s12957-018-1348-z","volume":"16","author":"S Hu","year":"2018","unstructured":"Hu S, Lou J, Zhang Y, Chen P (2018) Low heart rate variability relates to the progression of gastric cancer. World J Surg Oncol 16:49. https:\/\/doi.org\/10.1186\/s12957-018-1348-z","journal-title":"World J Surg Oncol"},{"key":"11229_CR34","doi-asserted-by":"publisher","unstructured":"Kim E-H, Park J-H, Lee S-M, Gwak M-S, Kim G-S, Kim M-H (2016) Preoperative depressed mood and perioperative heart rate variability in patients with hepatic cancer.\u00a0J Clin Anesth\u00a035332\u2013338. https:\/\/doi.org\/10.1016\/j.jclinane.2016.09.012","DOI":"10.1016\/j.jclinane.2016.09.012"},{"key":"11229_CR35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2022.110766","volume":"156","author":"WM Kitselaar","year":"2022","unstructured":"Kitselaar WM, de Morree HM, Trompenaars MW et al (2022) Fatigue after neurosurgery in patients with a brain tumor: the role of autonomic dysregulation and disturbed sleep. J Psychosom Res 156:110766. https:\/\/doi.org\/10.1016\/j.jpsychores.2022.110766","journal-title":"J Psychosom Res"},{"key":"11229_CR36","doi-asserted-by":"publisher","DOI":"10.2196\/25791","volume":"23","author":"CH Shih","year":"2021","unstructured":"Shih CH, Chou PC, Chou TL, Huang TW (2021) Measurement of cancer-related fatigue based on heart rate variability: observational study. J Med Internet Res 23:e25791. https:\/\/doi.org\/10.2196\/25791","journal-title":"J Med Internet Res"},{"key":"11229_CR37","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2023.1103979","volume":"10","author":"CH Shih","year":"2023","unstructured":"Shih CH, Chou PC, Chen JH et al (2023) Cancer-related fatigue classification based on heart rate variability signals from wearables. Front Med 10:1103979. https:\/\/doi.org\/10.3389\/fmed.2023.1103979","journal-title":"Front Med"},{"key":"11229_CR38","doi-asserted-by":"publisher","unstructured":"Tanigaiselvane DJ, Ravi RS, Singh AK\u00a0(2024) Cancer-related fatigue across sensory behavioral cognitive affective domains and HRV metrics: a prevalence study.\u00a0Int J Adv Sci Technol 21(1):473\u2013484. https:\/\/doi.org\/10.29070\/sd9zwm05","DOI":"10.29070\/sd9zwm05"},{"key":"11229_CR39","doi-asserted-by":"publisher","first-page":"71","DOI":"10.30773\/pi.2018.10.26","volume":"16","author":"HY Park","year":"2019","unstructured":"Park HY, Jeon HJ, Bang YR, Yoon IY (2019) Multidimensional comparison of cancer-related fatigue and chronic fatigue syndrome: the role of psychophysiological markers. Psychiatry Investig 16:71\u201379. https:\/\/doi.org\/10.30773\/pi.2018.10.26","journal-title":"Psychiatry Investig"},{"key":"11229_CR40","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1111\/j.1540-8167.2005.40788.x","volume":"16","author":"PK Stein","year":"2005","unstructured":"Stein PK, Domitrovich PP, Hui N et al (2005) Sometimes higher heart rate variability is not better heart rate variability: results of graphical and nonlinear analyses. J Cardiovasc Electrophysiol 16:954\u2013959. https:\/\/doi.org\/10.1111\/j.1540-8167.2005.40788.x","journal-title":"J Cardiovasc Electrophysiol"},{"key":"11229_CR41","doi-asserted-by":"publisher","first-page":"1395","DOI":"10.1016\/s0735-1097(01)01171-8","volume":"37","author":"TH M\u00e4kikallio","year":"2001","unstructured":"M\u00e4kikallio TH, Huikuri HV, M\u00e4kikallio A et al (2001) Prediction of sudden cardiac death by fractal analysis of heart rate variability in elderly subjects. J Am Coll Cardiol 37:1395\u20131402. https:\/\/doi.org\/10.1016\/s0735-1097(01)01171-8","journal-title":"J Am Coll Cardiol"},{"key":"11229_CR42","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1111\/j.1540-8167.2008.01232.x","volume":"19","author":"PK Stein","year":"2008","unstructured":"Stein PK, Barzilay JI, Chaves PHM et al (2008) Novel measures of heart rate variability predict cardiovascular mortality in older adults independent of traditional cardiovascular risk factors: the Cardiovascular Health Study (CHS). J Cardiovasc Electrophysiol 19:1169\u20131174. https:\/\/doi.org\/10.1111\/j.1540-8167.2008.01232.x","journal-title":"J Cardiovasc Electrophysiol"},{"key":"11229_CR43","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.jelectrocard.2007.11.005","volume":"41","author":"PK Stein","year":"2008","unstructured":"Stein PK, Le Q, Domitrovich PP (2008) Development of more erratic heart rate patterns is associated with mortality post-myocardial infarction. J Electrocardiol 41:110\u2013115. https:\/\/doi.org\/10.1016\/j.jelectrocard.2007.11.005","journal-title":"J Electrocardiol"},{"key":"11229_CR44","doi-asserted-by":"publisher","first-page":"2637","DOI":"10.21873\/anticanres.15044","volume":"41","author":"A Jang","year":"2021","unstructured":"Jang A, Seol YM (2021) Heart rate variability as a non-invasive objective parameter for predicting the occurrence of chemotherapy-induced peripheral neuropathy in patients with gastrointestinal cancer. Anticancer Res 41:2637\u20132645. https:\/\/doi.org\/10.21873\/anticanres.15044","journal-title":"Anticancer Res"},{"key":"11229_CR45","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2022.987835","volume":"13","author":"G Li","year":"2022","unstructured":"Li G, Wu S, Zhao H et al (2022) Non-invasive prognostic biomarker of lung cancer patients with brain metastases: recurrence quantification analysis of heart rate variability. Front Physiol 13:987835. https:\/\/doi.org\/10.3389\/fphys.2022.987835","journal-title":"Front Physiol"},{"key":"11229_CR46","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-35396-x","volume":"13","author":"J McGovern","year":"2023","unstructured":"McGovern J, Leadbitter S, Miller G et al (2023) The relationship between heart rate variability and TNM stage, co-morbidity, systemic inflammation and survival in patients with primary operable colorectal cancer. Sci Rep 13:8157. https:\/\/doi.org\/10.1038\/s41598-023-35396-x","journal-title":"Sci Rep"},{"key":"11229_CR47","doi-asserted-by":"publisher","DOI":"10.1186\/s40959-020-00065-9","volume":"6","author":"B Noor","year":"2020","unstructured":"Noor B, Akhavan S, Leuchter M et al (2020) Quantitative assessment of cardiovascular autonomic impairment in cancer survivors: a single center case series. Cardiooncology 6:11. https:\/\/doi.org\/10.1186\/s40959-020-00065-9","journal-title":"Cardiooncology"},{"key":"11229_CR48","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/503421","volume":"2013","author":"YM Wang","year":"2013","unstructured":"Wang YM, Wu HT, Huang EY et al (2013) Heart rate variability is associated with survival in patients with brain metastasis: a preliminary report. BioMed Res Int 2013:503421. https:\/\/doi.org\/10.1155\/2013\/503421","journal-title":"BioMed Res Int"}],"container-title":["Supportive Care in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-026-11229-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-026-11229-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00520-026-11229-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:48:52Z","timestamp":1792086532000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00520-026-11229-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,29]]},"references-count":48,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["11229"],"URL":"https:\/\/doi.org\/10.1007\/s00520-026-11229-1","relation":{},"ISSN":["0941-4355","1433-7339"],"issn-type":[{"value":"0941-4355","type":"print"},{"value":"1433-7339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,29]]},"assertion":[{"value":"28 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable. This study is a systematic review and meta-analysis of previously published studies and did not involve direct human participants.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"1034"}}