{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T22:24:26Z","timestamp":1776378266089,"version":"3.51.2"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Hepatobiliary Pancreat Surg"],"published-print":{"date-parts":[[2008,9]]},"DOI":"10.1007\/s00534-007-1269-7","type":"journal-article","created":{"date-parts":[[2008,10,3]],"date-time":"2008-10-03T07:19:22Z","timestamp":1223018362000},"page":"549-553","source":"Crossref","is-referenced-by-count":21,"title":["Multicentric pancreatic intraepithelial neoplasias (PanINs) presenting with the clinical features of chronic pancreatitis"],"prefix":"10.1007","volume":"15","author":[{"given":"Takayuki","family":"Aimoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiji","family":"Uchida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiharu","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Matsushita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Katsuno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazumitsu","family":"Chou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masao","family":"Kawamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zenya","family":"Naito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Tajiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,10,4]]},"reference":[{"key":"1269_CR1","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1097\/00000478-200105000-00003","volume":"25","author":"R.H. Hr\u00fcban","year":"2001","unstructured":"Hr\u00fcban RH, Adsay NV, Albores-Saavedra J, Compton C, Garrett ES, Goodman SN, et al. Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesions. Am J Surg Pathol 2001;25:579\u2013586.","journal-title":"Am J Surg Pathol"},{"key":"1269_CR2","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s00534-006-1170-9","volume":"14","author":"R.H. Hruban","year":"2007","unstructured":"Hruban RH, Takaori K, Canto M, Fishman EK, Campbell K, Brune K, et al. Clinical importance of precursor lesions in the pancreas. J Hepatobiliary Pancreat Surg 2007;14:255\u2013263.","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"1269_CR3","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1097\/01.mpa.0000186245.35716.18","volume":"31","author":"D.S. Longnecker","year":"2005","unstructured":"Longnecker DS, Adsay NV, Castillo CF, Hr\u00fcban RH, Kasugai T, Klimstra DS, et al. Histopathological diagnosis of pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms: interobserver agreement. Pancreas 2005;31:344\u2013349.","journal-title":"Pancreas"},{"key":"1269_CR4","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1097\/01.pas.0000126675.59108.80","volume":"28","author":"R.H. Hr\u00fcban","year":"2004","unstructured":"Hr\u00fcban RH, Takaori K, Klimstra D, Adsay NV, Albores-Saavedra J, Biankin AV, et al. An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms. Am J Surg Pathol 2004;28:977\u2013987.","journal-title":"Am J Surg Pathol"},{"key":"1269_CR5","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s00534-006-1169-2","volume":"14","author":"K. Nagata","year":"2007","unstructured":"Nagata K, Horinouchi M, Saitou M, Higashi M, Nomoto M, Goto M, et al. Mucin expression profile in pancreatic cancer and the precursor lesions. J Hepatobiliary Pancreat Surg 2007;14:243\u2013254.","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"1269_CR6","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1097\/01.pas.0000131556.22382.3c","volume":"28","author":"A.V. Biankin","year":"2004","unstructured":"Biankin AV, Kench JG, Biankin SA, Lee CS, Morey AL, Dijkman FP, et al. Pancreatic intraepithelial neoplasia in association with intraductal papillary mucinous neoplasms of the pancreas. Implications for disease progression and recurrence. Am J Surg Pathol 2004;28:1184\u20131192.","journal-title":"Am J Surg Pathol"},{"key":"1269_CR7","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1007\/s00428-005-0032-1","volume":"447","author":"S. Detlefsen","year":"2005","unstructured":"Detlefsen S, Sipos B, Feyerabend B, Kl\u00f6ppel G. Pancreatic fibrosis associated with age and ductal papillary hyperplasia. Virchows Arch 2005;447:800\u2013805.","journal-title":"Virchows Arch"},{"key":"1269_CR8","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1097\/00006676-199807000-00015","volume":"17","author":"K. Takaori","year":"1998","unstructured":"Takaori K, Matsusue S, Fujikawa T, Kobashi Y, Ito T, Matsuo Y, et al. Carcinoma in situ of the pancreas associated with localized fibrosis: a clue to early detection of neoplastic lesions arising from pancreatic ducts. Pancreas 1998;17:102\u2013105.","journal-title":"Pancreas"},{"key":"1269_CR9","first-page":"1067","volume":"30","author":"K. Brune","year":"2006","unstructured":"Brune K, Abe T, Canto M, O\u2019Malley L, Klein AP, Maitra A, et al. Multifocal neoplastic precursor lesions associated with lobular atrophy of the pancreas in patients having a strong family history of pancreatic cancer. Am J Surg Pathol 2006;30:1067\u20131076.","journal-title":"Am J Surg Pathol"},{"key":"1269_CR10","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/s00534-006-1146-9","volume":"14","author":"M. Inagaki","year":"2007","unstructured":"Inagaki M, Obara M, Kino S, Goto J, Suzuki S, Ishizaki A, et al. Pylorus-preserving total pancreatectomy for an intraductal papillary-mucinous neoplasm of the pancreas. J Hepatobiliary Pancreat Surg 2007;14:264\u2013269.","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"1269_CR11","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s00534-003-0756-8","volume":"10","author":"K. Takaori","year":"2003","unstructured":"Takaori K, Kobayashi Y, Matsusue S, Matsui K, Yamamoto T. Clinicopathological features of pancreatic intraepithelial neoplasias and their relationship to intraductal papillary-mucinous tumors. J Hepatobiliary Pancreat Surg 2003;10:125\u2013136.","journal-title":"J Hepatobiliary Pancreat Surg"}],"container-title":["Journal of Hepato-Biliary-Pancreatic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00534-007-1269-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00534-007-1269-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00534-007-1269-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T10:39:14Z","timestamp":1626950354000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00534-007-1269-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,9]]}},"alternative-id":["1269"],"URL":"https:\/\/doi.org\/10.1007\/s00534-007-1269-7","relation":{},"ISSN":["0944-1166","1436-0691"],"issn-type":[{"value":"0944-1166","type":"print"},{"value":"1436-0691","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9]]}}}