{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:48:41Z","timestamp":1761630521982},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2009,7,18]],"date-time":"2009-07-18T00:00:00Z","timestamp":1247875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2010,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/purpose<\/jats:title><jats:p>Living\u2010donor pancreas transplants (LDPs) were introduced at Chiba\u2010East National Hospital in 2004, and 12 LDPs have been performed at this institution to date. Based on the outcome of these 12 LDPs, the efficacy and safety of LDPs are herein discussed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twelve diabetic patients underwent LDPs; ten had simultaneous pancreas and kidney transplants from living donors, one had pancreas transplant after a kidney transplant from a living donor, and one had a pancreas transplant alone from a living donor. The donors were parents or brothers and the ABO blood types were incompatible in three LDPs. The procedures for the donor and recipient operations were performed according to the technique established by the University of Minnesota. Bladder drainage was used in 11 recipients and enteric drainage was used in one patient. Tacrolimus, basiliximab, mycophenolate mofetil, and prednisone were used for induction and immunosuppressive treatment. A splenectomy, double\u2010filtered plasmapheresis, and plasma exchange were added in the ABO\u2010incompatible LDPs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No complications were observed in the donors during hospitalization. The 1\u2010year survivals of the patients, kidney grafts, and pancreas grafts were 100, 100, and 100%, respectively. The 3\u2010year survivals were 91.7, 90, and 91.7%, respectively. Three patients developed leakage of pancreatic juice and one patient required a surgical procedure. Cytomegalovirus antigenemia was detected in five patients (42%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Based on the excellent outcome of the LDPs at this institution, LDPs is therefore expected to become a promising option for the treatment of patients with severe diabetes.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00534-009-0148-9","type":"journal-article","created":{"date-parts":[[2009,7,17]],"date-time":"2009-07-17T08:29:21Z","timestamp":1247819361000},"page":"101-107","source":"Crossref","is-referenced-by-count":32,"title":["Living donor pancreas transplantation in Japan"],"prefix":"10.1002","volume":"17","author":[{"given":"Takashi","family":"Kenmochi","sequence":"first","affiliation":[{"name":"Department of Surgery Chiba\u2010East National Hospital, National Hospital Organization (NHO)  673 Nitonacho, Chuo\u2010ku Chiba 260\u20108712 Japan"},{"name":"Clinical Research Center Chiba\u2010East National Hospital, National Hospital Organization (NHO)  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takehide","family":"Asano","sequence":"additional","affiliation":[{"name":"Department of Surgery Teikyo University, School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michihiro","family":"Maruyama","sequence":"additional","affiliation":[{"name":"Department of Surgery Chiba\u2010East National Hospital, National Hospital Organization (NHO)  673 Nitonacho, Chuo\u2010ku Chiba 260\u20108712 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Saigo","sequence":"additional","affiliation":[{"name":"Department of Surgery Chiba\u2010East National Hospital, National Hospital Organization (NHO)  673 Nitonacho, Chuo\u2010ku Chiba 260\u20108712 Japan"},{"name":"Clinical Research Center Chiba\u2010East National Hospital, National Hospital Organization (NHO)  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naotake","family":"Akutsu","sequence":"additional","affiliation":[{"name":"Department of Surgery Chiba\u2010East National Hospital, National Hospital Organization (NHO)  673 Nitonacho, Chuo\u2010ku Chiba 260\u20108712 Japan"},{"name":"Clinical Research Center Chiba\u2010East National Hospital, National Hospital Organization (NHO)  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chikara","family":"Iwashita","sequence":"additional","affiliation":[{"name":"Department of Surgery Chiba\u2010East National Hospital, National Hospital Organization (NHO)  673 Nitonacho, Chuo\u2010ku Chiba 260\u20108712 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunori","family":"Ohtsuki","sequence":"additional","affiliation":[{"name":"Department of Surgery Chiba\u2010East National Hospital, National Hospital Organization (NHO)  673 Nitonacho, Chuo\u2010ku Chiba 260\u20108712 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Clinical Research Center Chiba\u2010East National Hospital, National Hospital Organization (NHO)  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko","family":"Miyazaki","sequence":"additional","affiliation":[{"name":"Clinical Research Center Chiba\u2010East National Hospital, National Hospital Organization (NHO)  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,7,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2005.00378.x"},{"key":"e_1_2_6_3_1","unstructured":"International Pancreas Transplant Registry.Annual reports. (http:\/\/www.iptr.umn.edu\/IPTR\/annual_reports.html) (2004)."},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200104000-00003"},{"key":"e_1_2_6_5_1","first-page":"331","article-title":"A case of simultaneous pancreas and kidney transplantation from brain dead donor (in Japanese)","volume":"21","author":"Fukao K","year":"1986","journal-title":"Jpn J Transplant"},{"key":"e_1_2_6_6_1","unstructured":"ItoT IshibashiM SugitaniA NakajimaI TeraokaS GotohM et al.Present status of pancreas transplantation in Japan.Clin Transpl2004;167\u201375."},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2008.01.047"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00253405"},{"key":"e_1_2_6_9_1","first-page":"19","article-title":"Living\u2010related donor segmental pancreatectomy for transplantation","volume":"12","author":"Sutherland DER","year":"1980","journal-title":"Transplant Proc."},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199604270-00025"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199710000-00008"},{"key":"e_1_2_6_12_1","first-page":"466","article-title":"The first case of simultaneous pancreas\u2010kidney transplant from living donor in our country (in Japanese)","volume":"40","author":"Kenmochi T","year":"2005","journal-title":"Jpn J Transplant"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1965.tb01810.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/meta.2001.24217"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2008.08.067"},{"key":"e_1_2_6_16_1","first-page":"443","article-title":"Pancreas transplants from living\u2010related donors","volume":"26","author":"Sutherland DER","year":"1994","journal-title":"Transplant Proc."},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(00)02329-0"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(01)01010-9"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2008.08.070"}],"container-title":["Journal of Hepato-Biliary-Pancreatic Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1007%2Fs00534-009-0148-9","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00534-009-0148-9","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1007\/s00534-009-0148-9","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00534-009-0148-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T15:28:54Z","timestamp":1694446134000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00534-009-0148-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7,18]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["10.1007\/s00534-009-0148-9"],"URL":"https:\/\/doi.org\/10.1007\/s00534-009-0148-9","archive":["Portico"],"relation":{},"ISSN":["1868-6974","1868-6982"],"issn-type":[{"value":"1868-6974","type":"print"},{"value":"1868-6982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,7,18]]}}}