{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T01:10:59Z","timestamp":1783991459832,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2009,10,8]],"date-time":"2009-10-08T00:00:00Z","timestamp":1254960000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Bilioenteric anastomosis allows reflux of bowel fluid into bile ducts, resulting in reflux cholangitis. We sought to develop a reflux\u2010free procedure of bilioenteric anastomosis endowed using an artificial bile duct (ABD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study was performed in four groups of pigs. In Group A, end\u2010to\u2010side choledochoduodenostomy using the interposed ABD with its distal end wrapped by the duodenal seromuscular layer was performed. In Group B, conventional end\u2010to\u2010side choledochoduodenostomy using the ABD was performed. In Group C, conventional end\u2010to\u2010side choledochoduodenostomy was performed. In Group D, sham operation was performed. In each groups, 12 weeks later, animals were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Bile amylase levels were significantly lower in Group A (36.9 \u00b1 21.7 U\/L) compared with Group B (469 \u00b1 140.9 U\/L). No significant differences were observed in bile amylase levels between Groups A and D or between Groups B and C. On histology, the neo\u2010bile duct in Group A was covered with the duodenal muscular layer at the orifice into the intestinal tract.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study suggests that the ABD is useful in the regeneration of extrahepatic bile ducts and that to bury the ABD in the duodenum can be a preventive measure against reflux of bowel fluid to bile ducts.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00534-009-0178-3","type":"journal-article","created":{"date-parts":[[2009,10,7]],"date-time":"2009-10-07T11:27:05Z","timestamp":1254914825000},"page":"284-290","source":"Crossref","is-referenced-by-count":9,"title":["Development of a novel reflux\u2010free bilioenteric anastomosis procedure by using a bioabsorbable polymer tube"],"prefix":"10.1002","volume":"17","author":[{"given":"Masayasu","family":"Aikawa","sequence":"first","affiliation":[{"name":"Gastrointestinal Center Saitama Medical University International Medical Center  1397\u20101 Yamane, Hidaka Saitama 350\u20101298 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuo","family":"Miyazawa","sequence":"additional","affiliation":[{"name":"Gastrointestinal Center Saitama Medical University International Medical Center  1397\u20101 Yamane, Hidaka Saitama 350\u20101298 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuya","family":"Okada","sequence":"additional","affiliation":[{"name":"Gastrointestinal Center Saitama Medical University International Medical Center  1397\u20101 Yamane, Hidaka Saitama 350\u20101298 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuko","family":"Toshimitsu","sequence":"additional","affiliation":[{"name":"Gastrointestinal Center Saitama Medical University International Medical Center  1397\u20101 Yamane, Hidaka Saitama 350\u20101298 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kojun","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Gastrointestinal Center Saitama Medical University International Medical Center  1397\u20101 Yamane, Hidaka Saitama 350\u20101298 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoe","family":"Akimoto","sequence":"additional","affiliation":[{"name":"Gastrointestinal Center Saitama Medical University International Medical Center  1397\u20101 Yamane, Hidaka Saitama 350\u20101298 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isamu","family":"Koyama","sequence":"additional","affiliation":[{"name":"Gastrointestinal Center Saitama Medical University International Medical Center  1397\u20101 Yamane, Hidaka Saitama 350\u20101298 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshito","family":"Ikada","sequence":"additional","affiliation":[{"name":"Gastrointestinal Center Saitama Medical University International Medical Center  1397\u20101 Yamane, Hidaka Saitama 350\u20101298 Japan"},{"name":"Division of Life Science Nara Medical University  Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,10,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199106000-00014"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00294736"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200108000-00011"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.51.1.128"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.147.3.513"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800760509"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000071761"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02811081"},{"key":"e_1_2_6_10_1","first-page":"200","article-title":"Hepatobiliary scintigraphy after biliary reconstruction\u2010Roux Y and RY\u2010DJ","volume":"52","author":"Hashimoto 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