{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T18:34:55Z","timestamp":1775327695558,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2010,5,12]],"date-time":"2010-05-12T00:00:00Z","timestamp":1273622400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Long\u2010term hemodynamic effects and clinical outcomes after balloon\u2010occluded retrograde transvenous obliteration (B\u2010RTO) remain unclear. The purpose of this study was to evaluate long\u2010term clinical results and effects on portal hemodynamics after B\u2010RTO for the treatment of gastric varices with spontaneous gastrorenal shunt.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 21 patients with cirrhosis and gastric varices treated by B\u2010RTO were evaluated. The cumulative survival rate was calculated, portal blood flow was measured by Doppler ultrasonography, and liver function was estimated on the basis of Child\u2010Pugh classification before and 1 year after B\u2010RTO.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Gastric varices disappeared or decreased markedly in size in all patients. Overall cumulative survival rates at 1, 3 and 5 years were 90.48, 71.11 and 53.71%, respectively. Portal blood flow increased significantly from 681.9 \u00b1 294.9 to 837.0 \u00b1 279.1 ml\/min (<jats:italic>p<\/jats:italic> = 0.0125) after B\u2010RTO. Child\u2010Pugh score was not significantly changed (<jats:italic>p<\/jats:italic> = 0.755) after obliteration, but serum albumin was elevated significantly from 3.49 \u00b1 0.49 to 3.75 \u00b1 0.53 g\/dl (<jats:italic>p<\/jats:italic> = 0.0459). The ascites score was significantly increased (<jats:italic>p<\/jats:italic> = 0.0455) after B\u2010RTO, but all cases of ascites could be controlled with medication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Balloon\u2010occluded retrograde transvenous obliteration is a safe and effective treatment for gastric varices with gastrorenal shunt. Portal blood flow and serum albumin parameters are increased, and liver function is unchanged after B\u2010RTO.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00534-010-0292-2","type":"journal-article","created":{"date-parts":[[2010,5,11]],"date-time":"2010-05-11T02:06:06Z","timestamp":1273543566000},"page":"898-903","source":"Crossref","is-referenced-by-count":9,"title":["Portal hemodynamics and clinical outcomes of patients with gastric varices after balloon\u2010occluded retrograde transvenous obliteration"],"prefix":"10.1002","volume":"17","author":[{"given":"Akiyoshi","family":"Kasuga","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Funabashi Municipal Medical Center  Chiba Japan"},{"name":"Department of Gastroenterology Chiba University School of Medicine  1\u20108\u20101 Inohana, Chuo\u2010ku Chiba Chiba 260\u20108677 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideaki","family":"Mizumoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Funabashi Municipal Medical Center  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoichi","family":"Matsutani","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Oncology, Graduate School of Medicine Chiba University  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akitoshi","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Funabashi Municipal Medical Center  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsunehiro","family":"Endo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Funabashi Municipal Medical Center  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Ando","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Funabashi Municipal Medical Center  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seigo","family":"Yukisawa","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Oncology, Graduate School of Medicine Chiba University  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Maruyama","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Oncology, Graduate School of Medicine Chiba University  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Yokosuka","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Oncology, Graduate School of Medicine Chiba University  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,5,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840160607"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.211.2.r99ma25349"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(88)90501-X"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(86)71843-9"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(81)73224-3"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.167.5.8911204"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800750809"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.1996.tb00010.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1051-0443(07)61912-5"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.184.4.01841340"},{"issue":"6","key":"e_1_2_5_12_1","first-page":"1026","article-title":"Changes in liver function parameters after occlusion of gastrorenal shunts with balloon\u2010occluded retrograde transvenous obliteration","volume":"92","author":"Akahane T","year":"1997","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.2003.03087.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.181.4.1811011"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000018874"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1443-1661.2009.00929.x"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1098252"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(83)72489-2"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510250209"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(01)21563-3"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.178.5.1781167"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-007-2077-1"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1999.0029900515"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(02)70437-9"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2008.05549.x"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1872-034X.2007.00282.x"}],"container-title":["Journal of Hepato-Biliary-Pancreatic Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1007%2Fs00534-010-0292-2","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00534-010-0292-2","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1007\/s00534-010-0292-2","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00534-010-0292-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T15:39:01Z","timestamp":1694446741000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00534-010-0292-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,12]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["10.1007\/s00534-010-0292-2"],"URL":"https:\/\/doi.org\/10.1007\/s00534-010-0292-2","archive":["Portico"],"relation":{},"ISSN":["1868-6974","1868-6982"],"issn-type":[{"value":"1868-6974","type":"print"},{"value":"1868-6982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5,12]]}}}