{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T17:36:50Z","timestamp":1778089010637,"version":"3.51.4"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2010,1,14]],"date-time":"2010-01-14T00:00:00Z","timestamp":1263427200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Gastroenterol"],"published-print":{"date-parts":[[2010,3]]},"DOI":"10.1007\/s00535-009-0192-x","type":"journal-article","created":{"date-parts":[[2010,1,13]],"date-time":"2010-01-13T05:25:08Z","timestamp":1263360308000},"page":"277-284","source":"Crossref","is-referenced-by-count":31,"title":["Colitis causes delay in puberty in female mice out of proportion to changes in leptin and corticosterone"],"prefix":"10.1007","volume":"45","author":[{"given":"Mark D.","family":"DeBoer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongli","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Cohn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,1,14]]},"reference":[{"issue":"2","key":"192_CR1","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1203\/00006450-200302000-00002","volume":"53","author":"AB Ballinger","year":"2003","unstructured":"Ballinger AB, Savage MO, Sanderson IR. Delayed puberty associated with inflammatory bowel disease. Pediatr Res. 2003;53(2):205\u201310.","journal-title":"Pediatr Res"},{"issue":"1","key":"192_CR2","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0950-3528(06)80020-5","volume":"8","author":"CE Brain","year":"1994","unstructured":"Brain CE, Savage MO. Growth and puberty in chronic inflammatory bowel disease. Baillieres Clin Gastroenterol. 1994;8(1):83\u2013100.","journal-title":"Baillieres Clin Gastroenterol"},{"issue":"6939","key":"192_CR3","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1136\/bmj.308.6939.1259","volume":"308","author":"A Ferguson","year":"1994","unstructured":"Ferguson A, Sedgwick DM. Juvenile onset inflammatory bowel disease: height and body mass index in adult life. BMJ. 1994;308(6939):1259\u201363.","journal-title":"BMJ"},{"issue":"8","key":"192_CR4","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1097\/00054725-200608000-00003","volume":"12","author":"AR Otley","year":"2006","unstructured":"Otley AR, Griffiths AM, Hale S, Kugathasan S, Pfefferkorn M, Mezoff A, et al. Health-related quality of life in the first year after a diagnosis of pediatric inflammatory bowel disease. Inflamm Bowel Dis. 2006;12(8):684\u201391.","journal-title":"Inflamm Bowel Dis"},{"issue":"4","key":"192_CR5","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1002\/ibd.20039","volume":"13","author":"M Paganelli","year":"2007","unstructured":"Paganelli M, Albanese C, Borrelli O, Civitelli F, Canitano N, Viola F, et al. Inflammation is the main determinant of low bone mineral density in pediatric inflammatory bowel disease. Inflamm Bowel Dis. 2007;13(4):416\u201323.","journal-title":"Inflamm Bowel Dis"},{"issue":"suppl 2","key":"192_CR6","first-page":"53","volume":"57","author":"D Simon","year":"2002","unstructured":"Simon D. Puberty in chronically diseased patients. Horm Res. 2002;57(suppl 2):53\u20136.","journal-title":"Horm Res"},{"issue":"6","key":"192_CR7","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1097\/MED.0b013e3282f1cfdc","volume":"14","author":"S Bluher","year":"2007","unstructured":"Bluher S, Mantzoros CS. Leptin in reproduction. Curr Opin Endocrinol Diabetes Obes. 2007;14(6):458\u201364.","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"issue":"22","key":"192_CR8","doi-asserted-by":"crossref","first-page":"8481","DOI":"10.1073\/pnas.0505429103","volume":"103","author":"JL Chan","year":"2006","unstructured":"Chan JL, Matarese G, Shetty GK, Raciti P, Kelesidis I, Aufiero D, et al. Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans. Proc Natl Acad Sci USA. 2006;103(22):8481\u20136.","journal-title":"Proc Natl Acad Sci USA"},{"issue":"3","key":"192_CR9","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1172\/JCI119172","volume":"99","author":"RS Ahima","year":"1997","unstructured":"Ahima RS, Dushay J, Flier SN, Prabakaran D, Flier JS. Leptin accelerates the onset of puberty in normal female mice. J Clin Invest. 1997;99(3):391\u20135.","journal-title":"J Clin Invest"},{"issue":"2","key":"192_CR10","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S1043-2760(00)00352-0","volume":"12","author":"M Caprio","year":"2001","unstructured":"Caprio M, Fabbrini E, Isidori AM, Aversa A, Fabbri A. Leptin in reproduction. Trends Endocrinol Metab. 2001;12(2):65\u201372.","journal-title":"Trends Endocrinol Metab"},{"issue":"2","key":"192_CR11","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1210\/endo.138.2.5054","volume":"138","author":"CC Cheung","year":"1997","unstructured":"Cheung CC, Thornton JE, Kuijper JL, Weigle DS, Clifton DK, Steiner RA. Leptin is a metabolic gate for the onset of puberty in the female rat. Endocrinology. 1997;138(2):855\u20138.","journal-title":"Endocrinology"},{"issue":"10","key":"192_CR12","doi-asserted-by":"crossref","first-page":"4601","DOI":"10.1210\/en.2007-0500","volume":"148","author":"RM Luque","year":"2007","unstructured":"Luque RM, Kineman RD, Tena-Sempere M. Regulation of hypothalamic expression of KiSS-1 and GPR54 genes by metabolic factors: analyses using mouse models and a cell line. Endocrinology. 2007;148(10):4601\u201311.","journal-title":"Endocrinology"},{"issue":"3","key":"192_CR13","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1038\/ng0396-318","volume":"12","author":"FF Chehab","year":"1996","unstructured":"Chehab FF, Lim ME, Lu R. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat Genet. 1996;12(3):318\u201320.","journal-title":"Nat Genet"},{"issue":"4","key":"192_CR14","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1111\/j.1365-2826.2006.01417.x","volume":"18","author":"JT Smith","year":"2006","unstructured":"Smith JT, Acohido BV, Clifton DK, Steiner RA. KiSS-1 neurones are direct targets for leptin in the ob\/ob mouse. J Neuroendocrinol. 2006;18(4):298\u2013303.","journal-title":"J Neuroendocrinol"},{"issue":"4","key":"192_CR15","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1006\/prep.1993.1038","volume":"4","author":"S Kawa","year":"1993","unstructured":"Kawa S, Kumar A, Smith JS, Becerra SP, Beard WA, Wilson SH, et al. Expression and purification of the HIV-1 reverse transcriptase using the baculovirus expression vector system. Protein Expr Purif. 1993;4(4):298\u2013303.","journal-title":"Protein Expr Purif"},{"issue":"2","key":"192_CR16","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1055\/s-2002-32505","volume":"20","author":"IS Farooqi","year":"2002","unstructured":"Farooqi IS. Leptin and the onset of puberty: insights from rodent and human genetics. Semin Reprod Med. 2002;20(2):139\u201344.","journal-title":"Semin Reprod Med"},{"issue":"6","key":"192_CR17","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/sj.mp.4000418","volume":"3","author":"L Audi","year":"1998","unstructured":"Audi L, Mantzoros CS, Vidal-Puig A, Vargas D, Gussinye M, Carrascosa A. Leptin in relation to resumption of menses in women with anorexia nervosa. Mol Psychiatry. 1998;3(6):544\u20137.","journal-title":"Mol Psychiatry"},{"issue":"7","key":"192_CR18","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1055\/s-1999-8834","volume":"20","author":"N Matejek","year":"1999","unstructured":"Matejek N, Weimann E, Witzel C, Molenkamp G, Schwidergall S, Bohles H. Hypoleptinaemia in patients with anorexia nervosa and in elite gymnasts with anorexia athletica. Int J Sports Med. 1999;20(7):451\u20136.","journal-title":"Int J Sports Med"},{"issue":"6588","key":"192_CR19","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1038\/382250a0","volume":"382","author":"RS Ahima","year":"1996","unstructured":"Ahima RS, Prabakaran D, Mantzoros C, Qu D, Lowell B, Maratos-Flier E, et al. Role of leptin in the neuroendocrine response to fasting. Nature. 1996;382(6588):250\u20132.","journal-title":"Nature"},{"issue":"6","key":"192_CR20","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1542\/peds.2004-0540","volume":"114","author":"M Misra","year":"2004","unstructured":"Misra M, Aggarwal A, Miller KK, Almazan C, Worley M, Soyka LA, et al. Effects of anorexia nervosa on clinical, hematologic, biochemical, and bone density parameters in community-dwelling adolescent girls. Pediatrics. 2004;114(6):1574\u201383.","journal-title":"Pediatrics"},{"issue":"7","key":"192_CR21","doi-asserted-by":"crossref","first-page":"3486","DOI":"10.1210\/jc.2003-032251","volume":"89","author":"M Misra","year":"2004","unstructured":"Misra M, Miller KK, Almazan C, Ramaswamy K, Aggarwal A, Herzog DB, et al. Hormonal and body composition predictors of soluble leptin receptor, leptin, and free leptin index in adolescent girls with anorexia nervosa and controls and relation to insulin sensitivity. J Clin Endocrinol Metab. 2004;89(7):3486\u201395.","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"192_CR22","doi-asserted-by":"crossref","first-page":"R1483","DOI":"10.1152\/ajpregu.2001.281.5.R1483","volume":"281","author":"OG Azooz","year":"2001","unstructured":"Azooz OG, Farthing MJ, Savage MO, Ballinger AB. Delayed puberty and response to testosterone in a rat model of colitis. Am J Physiol Regul Integr Comp Physiol. 2001;281(5):R1483\u201391.","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"6","key":"192_CR23","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1136\/gut.43.6.783","volume":"43","author":"M Barbier","year":"1998","unstructured":"Barbier M, Cherbut C, Aube AC, Blottiere HM, Galmiche JP. Elevated plasma leptin concentrations in early stages of experimental intestinal inflammation in rats. Gut. 1998;43(6):783\u201390.","journal-title":"Gut"},{"issue":"3","key":"192_CR24","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/nprot.2007.41","volume":"2","author":"S Wirtz","year":"2007","unstructured":"Wirtz S, Neufert C, Weigmann B, Neurath MF. Chemically induced mouse models of intestinal inflammation. Nat Protoc. 2007;2(3):541\u20136.","journal-title":"Nat Protoc"},{"issue":"4","key":"192_CR25","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1095\/biolreprod42.4.649","volume":"42","author":"JF Nelson","year":"1990","unstructured":"Nelson JF, Karelus K, Felicio LS, Johnson TE. Genetic influences on the timing of puberty in mice. Biol Reprod. 1990;42(4):649\u201355.","journal-title":"Biol Reprod"},{"issue":"6","key":"192_CR26","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1095\/biolreprod.109.079301","volume":"81","author":"DS Brill","year":"2009","unstructured":"Brill DS, Moenter SM. Androgen receptor antagonism and an insulin sensitizer block the advancement of vaginal opening by high-fat diet in mice. Biol Reprod. 2009;81(6):1093\u20138.","journal-title":"Biol Reprod"},{"issue":"12","key":"192_CR27","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1289\/ehp.10165","volume":"115","author":"JE Thigpen","year":"2007","unstructured":"Thigpen JE, Setchell KD, Padilla-Banks E, Haseman JK, Saunders HE, Caviness GF, et al. Variations in phytoestrogen content between different mill dates of the same diet produces significant differences in the time of vaginal opening in CD-1 mice and F344 rats but not in CD Sprague-Dawley rats. Environ Health Perspect. 2007;115(12):1717\u201326.","journal-title":"Environ Health Perspect"},{"issue":"3","key":"192_CR28","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1677\/joe.1.07049","volume":"193","author":"Y Zhou","year":"2007","unstructured":"Zhou Y, Zhu W, Guo Z, Zhao Y, Song Z, Xiao J. Effects of maternal nuclear genome on the timing of puberty in mice offspring. J Endocrinol. 2007;193(3):405\u201312.","journal-title":"J Endocrinol"},{"issue":"11","key":"192_CR29","doi-asserted-by":"crossref","first-page":"5132","DOI":"10.1210\/en.2006-0745","volume":"147","author":"BM Nathan","year":"2006","unstructured":"Nathan BM, Hodges CA, Supelak PJ, Burrage LC, Nadeau JH, Palmert MR. A quantitative trait locus on chromosome 6 regulates the onset of puberty in mice. Endocrinology. 2006;147(11):5132\u20138.","journal-title":"Endocrinology"},{"issue":"6","key":"192_CR30","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1053\/gast.2001.29568","volume":"121","author":"RC Burns","year":"2001","unstructured":"Burns RC, Rivera-Nieves J, Moskaluk CA, Matsumoto S, Cominelli F, Ley K. Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1\/Yit adoptive transfer model of Crohn\u2019s disease in mice. Gastroenterology. 2001;121(6):1428\u201336.","journal-title":"Gastroenterology"},{"issue":"14","key":"192_CR31","doi-asserted-by":"crossref","first-page":"8366","DOI":"10.1073\/pnas.1432897100","volume":"100","author":"M Marini","year":"2003","unstructured":"Marini M, Bamias G, Rivera-Nieves J, Moskaluk CA, Hoang SB, Ross WG, et al. TNF-alpha neutralization ameliorates the severity of murine Crohn\u2019s-like ileitis by abrogation of intestinal epithelial cell apoptosis. Proc Natl Acad Sci USA. 2003;100(14):8366\u201371.","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"192_CR32","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1095\/biolreprod53.1.103","volume":"53","author":"PC Fallest","year":"1995","unstructured":"Fallest PC, Trader GL, Darrow JM, Shupnik MA. Regulation of rat luteinizing hormone beta gene expression in transgenic mice by steroids and a gonadotropin-releasing hormone antagonist. Biol Reprod. 1995;53(1):103\u20139.","journal-title":"Biol Reprod"},{"issue":"4","key":"192_CR33","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1210\/endo.132.4.8462469","volume":"132","author":"AM Haavisto","year":"1993","unstructured":"Haavisto AM, Pettersson K, Bergendahl M, Perheentupa A, Roser JF, Huhtaniemi I. A supersensitive immunofluorometric assay for rat luteinizing hormone. Endocrinology. 1993;132(4):1687\u201391.","journal-title":"Endocrinology"},{"issue":"3","key":"192_CR34","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0739-7240(87)90011-7","volume":"4","author":"RL Matteri","year":"1987","unstructured":"Matteri RL, Roser JF, Baldwin DM, Lipovetsky V, Papkoff H. Characterization of a monoclonal antibody which detects luteinizing hormone from diverse mammalian species. Domest Anim Endocrinol. 1987;4(3):157\u201365.","journal-title":"Domest Anim Endocrinol"},{"issue":"6","key":"192_CR35","first-page":"1880","volume":"29","author":"VL Gay","year":"1970","unstructured":"Gay VL, Midgley AR Jr, Niswender GD. Patterns of gonadotrophin secretion associated with ovulation. Fed Proc. 1970;29(6):1880\u20137.","journal-title":"Fed Proc"},{"issue":"7447","key":"192_CR36","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1136\/bmj.328.7447.1073","volume":"328","author":"JM Bland","year":"2004","unstructured":"Bland JM, Altman DG. The logrank test. BMJ. 2004;328(7447):1073.","journal-title":"BMJ"},{"issue":"11","key":"192_CR37","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1111\/j.1651-2227.2004.tb02628.x","volume":"93","author":"I Swenne","year":"2004","unstructured":"Swenne I. Weight requirements for return of menstruations in teenage girls with eating disorders, weight loss and secondary amenorrhoea. Acta Paediatr. 2004;93(11):1449\u201355.","journal-title":"Acta Paediatr"},{"issue":"10","key":"192_CR38","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1056\/NEJMoa040388","volume":"351","author":"CK Welt","year":"2004","unstructured":"Welt CK, Chan JL, Bullen J, Murphy R, Smith P, DePaoli AM, et al. Recombinant human leptin in women with hypothalamic amenorrhea. N Engl J Med. 2004;351(10):987\u201397.","journal-title":"N Engl J Med"},{"issue":"5","key":"192_CR39","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1097\/00005176-199805000-00003","volume":"26","author":"AG Hoppin","year":"1998","unstructured":"Hoppin AG, Kaplan LM, Zurakowski D, Leichtner AM, Bousvaros A. Serum leptin in children and young adults with inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 1998;26(5):500\u20135.","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"5","key":"192_CR40","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1136\/gut.44.5.588","volume":"44","author":"A Ballinger","year":"1999","unstructured":"Ballinger A. Divergency of leptin response in intestinal inflammation. Gut. 1999;44(5):588\u20139.","journal-title":"Gut"},{"issue":"12","key":"192_CR41","doi-asserted-by":"crossref","first-page":"4080","DOI":"10.1210\/jcem.82.12.4408","volume":"82","author":"MS Zumbach","year":"1997","unstructured":"Zumbach MS, Boehme MW, Wahl P, Stremmel W, Ziegler R, Nawroth PP. Tumor necrosis factor increases serum leptin levels in humans. J Clin Endocrinol Metab. 1997;82(12):4080\u20132.","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"192_CR42","doi-asserted-by":"crossref","first-page":"R1348","DOI":"10.1152\/ajpregu.00260.2001","volume":"282","author":"K Kojima","year":"2002","unstructured":"Kojima K, Naruse Y, Iijima N, Wakabayashi N, Mitsufuji S, Ibata Y, et al. HPA-axis responses during experimental colitis in the rat. Am J Physiol Regul Integr Comp Physiol. 2002;282(5):R1348\u201355.","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"2","key":"192_CR43","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1097\/00130478-200204000-00004","volume":"3","author":"K Menon","year":"2002","unstructured":"Menon K, Clarson C. Adrenal function in pediatric critical illness. Pediatr Crit Care Med. 2002;3(2):112\u20136.","journal-title":"Pediatr Crit Care Med"},{"issue":"10","key":"192_CR44","doi-asserted-by":"crossref","first-page":"4968","DOI":"10.1210\/en.2006-0347","volume":"147","author":"SO Reber","year":"2006","unstructured":"Reber SO, Obermeier F, Straub RH, Falk W, Neumann ID. Chronic intermittent psychosocial stress (social defeat\/overcrowding) in mice increases the severity of an acute DSS-induced colitis and impairs regeneration. Endocrinology. 2006;147(10):4968\u201376.","journal-title":"Endocrinology"},{"issue":"4","key":"192_CR45","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1210\/endo.138.4.5044","volume":"138","author":"RE Nappi","year":"1997","unstructured":"Nappi RE, Rivest S. Effect of immune and metabolic challenges on the luteinizing hormone-releasing hormone neuronal system in cycling female rats: an evaluation at the transcriptional level. Endocrinology. 1997;138(4):1374\u201384.","journal-title":"Endocrinology"},{"issue":"9","key":"192_CR46","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1056\/NEJMoa066494","volume":"357","author":"T Raivio","year":"2007","unstructured":"Raivio T, Falardeau J, Dwyer A, Quinton R, Hayes FJ, Hughes VA, et al. Reversal of idiopathic hypogonadotropic hypogonadism. N Engl J Med. 2007;357(9):863\u201373.","journal-title":"N Engl J Med"},{"issue":"4","key":"192_CR47","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1159\/000126155","volume":"55","author":"KJ Darney Jr","year":"1992","unstructured":"Darney KJ Jr, Goldman JM, Vandenbergh JG. Neuroendocrine responses to social regulation of puberty in the female house mouse. Neuroendocrinology. 1992;55(4):434\u201343.","journal-title":"Neuroendocrinology"}],"container-title":["Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00535-009-0192-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00535-009-0192-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00535-009-0192-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T02:37:47Z","timestamp":1559097467000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00535-009-0192-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,14]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["192"],"URL":"https:\/\/doi.org\/10.1007\/s00535-009-0192-x","relation":{},"ISSN":["0944-1174","1435-5922"],"issn-type":[{"value":"0944-1174","type":"print"},{"value":"1435-5922","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,14]]}}}